Rat CXCL7/Thymus Chemokine-1 Antibody Summary
Ile46-Ile107
Accession # NP_714943
Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Scientific Data
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Chemotaxis Induced by CXCL7/Thymus Chemokine‑1 and Neutralization by Rat CXCL7/Thymus Chemokine‑1 Antibody. Recombinant Rat CXCL7/Thymus Chemokine-1 (Catalog # 1116-CK) chemo-attracts the BaF3 mouse pro-B cell line transfected with human CXCR2 in a dose-dependent manner (orange line). The amount of cells that migrated through to the lower chemotaxis chamber was measured by Resazurin (Catalog # AR002). Chemotaxis elicited by Recombinant Rat CXCL7/Thymus Chemokine-1 (0.04 µg/mL) is neutralized (green line) by increasing concentrations of Goat Anti-Rat CXCL7/Thymus Chemokine-1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1116). The ND50 is typically 0.8-4.0 µg/mL.
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: CXCL7/Thymus Chemokine-1
CXCL7 is a member of the alpha (CXC) subfamily of chemokines. Rat CXCL7 cDNA encodes a 111 amino acid residue precursor protein. Rat CXCL7 shares 72% amino acid sequence identity with mouse CXCL7 (accession number AAG36786). The recombinant rat CXCL7 produced by R&D Systems has been shown to chemoattract human CXCR2 transfected mouse BaF/3 cells, but not human CXCR1 transfected mouse BaF/3 cells.
1rh6Ckine, rm6Ckine, rhBLC/BCA‑1, rmBLC, rhBRAK, rmBRAK, rmC10, rhCCL28, rmCCL28, rrCINC‑2a, rrCINC‑2b, rrCINC‑3, rhCKb8‑1, rvCMV UL146, rmCRG‑2, rhCTACK, rmCTACK, rhCXCL16, rmCXCL16, rhENA‑78, rhEotaxin, rmEotaxin, rhEotaxin‑2, rmEotaxin‑2, rhEotaxin‑3, rhFractalkine, rmFractalkine, rrFractalkine, rhGCP‑2, rmGCP‑2, rhGROa, rhGROb, rhGROg, rhHCC‑1, rhHCC‑4, rhI‑309, rhIL‑8, rpIL‑8, rcrIP‑10, rhIP‑10, rhI‑TAC, rmI‑TAC, rmJE, rmKC, rhLeukotactin-1, rrLIX, rmLungkine, rhLymphotactin, rmLymphotactin, rmMARC, rhMCP‑1, rhMCP‑2, rmMCP‑2, rhMCP‑3, rhMCP‑4, rmMCP‑5, rvMCV type 2, rhMDC, rmMDC, rhMIG, rmMIG, rcrMIP‑1a, rhMIP‑1a, rmMIP‑1a, rcrMIP‑1b, rhMIP‑1b, rmMIP‑1b, rhMIP‑1d, rmMIP‑1g, rmMIP‑2, rhMIP‑3a, rmMIP‑3a, rrMIP‑3a, rhMIP‑3b, rmMIP‑3b, rvMIP‑I, rvMIP‑II, rvMIP‑III, rhMPIF‑1, rhNAP‑2, rhPARC, rhPF4, rcrRANTES, rhRANTES, rmRANTES, rhSDF‑1a, rmSDF‑1a, rhSDF‑1b, rhTARC, rmTARC, rmTCA‑3, rhTeck, rmTeck
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Product Datasheets
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