Quinelorane hydrochloride
Chemical Name: (5aR,9aR)-5,5a,6,7,8,9,9a,10-Octahydro-6-propylpyrido[2,3-g]quinazolin-2-amine dihydrochloride
Purity: ≥99%
Biological Activity
Quinelorane hydrochloride is a dopamine D2 and D3 receptor agonist; Ki values are 5.7 and 3.4 nM respectively.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Additional Information
Background References
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Preclinical studies on quinelorane, a potent and highly selective D2-DArgic agonist.
Foreman et al.
J.Pharmacol.Exp.Ther., 1989;250:227 -
Effects of the selective DArgic D2 agonist quinelorane on the activity of DArgic and noradrenergic neurons projecting to the diencephalon of the rat.
Eaton et al.
J.Pharmacol.Exp.Ther., 1994;268:645 -
Comparison of D2 and D3 DA receptor affinity of DArgic compounds in the rat brain.
Flietstra and Levant
Life Sci., 1998;62:1825
Product Datasheets
Citation for Quinelorane hydrochloride
The citations listed below are publications that use Tocris products. Selected citations for Quinelorane hydrochloride include:
1 Citation: Showing 1 - 1
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Gene-environment interactions affect long-term depression (LTD) through changes in DA receptor affinity in Snap25 deficient mice.
Authors: Baca Et al.
Brain Res 2013;1532:85
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