Home / Non-selective 5-HT2 Receptor Antagonists / Quetiapine hemifumarate

Quetiapine hemifumarate

Catalog #: 4735 Datasheet
Catalog # Availability Size / Price Qty
4735/50
Quetiapine hemifumarate | CAS No. 111974-72-2 | Non-selective 5-HT2 Receptor Antagonists
1 Image
Description: 5-HT2 antagonist; also D2 antagonist; atypical antipsychotic
Alternative Names: ICI 204,636

Chemical Name: 2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol hemifumarate

Purity: ≥99%

Product Details
Supplemental Products
Reviews
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

Quetiapine hemifumarate is an atypical antipsychotic. Displays antagonist activity at serotonin (5-HT2) and dopamine (D2) receptors (IC50 values are 148 and 329 nM respectively). Lacks affinity at either D1 or muscarinic receptors.

Technical Data

M.Wt:
441.54
Formula:
C21H25N3O2S.0.5C4H4O4
Solubility:
Soluble to 50 mM in DMSO
Purity:
≥99%
Storage:
Store at +4°C
CAS No:
111974-72-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Seroquel: biochemical profile of a potential atypical antipsychotic.
    Saller and Salama
    Psychopharmacology (Berl.), 1993;112:285
  2. Activity of "seroquel" (ICI 204,636) in animal models for atypical properties of antipsychotics: a comparison with cloz.
    Ellenbroek et al.
    Neuropsychopharmacology, 1996;15:406

Product Datasheets

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for Quetiapine hemifumarate

There are currently no reviews for this product. Be the first to review Quetiapine hemifumarate and earn rewards!

Have you used Quetiapine hemifumarate?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.