Proteome Profiler Mouse Angiogenesis Array Kit
Proteome Profiler Mouse Angiogenesis Array Kit Summary
A membrane-based antibody array for the parallel determination of the relative levels of selected angiogenesis-related proteins. Validated for analyte detection in cell culture supernates, cell lysates, tissue lysates or serum.
Key Benefits
- Detects 53 mouse angiogenesis-related proteins simultaneously
- Requires no specialized equipment
Principle of the Array
The Proteome Profiler Mouse Angiogenesis Array Kit is a membrane-based sandwich immunoassay. Samples are mixed with a cocktail of biotinylated detection antibodies (Step 1) and then incubated with the array membrane which is spotted in duplicate with capture antibodies to specific target proteins (Step 2). Captured proteins are visualized using chemiluminescent detection reagents (Step 3). The signal produced is proportional to the amount of analyte bound. Analytes include soluble growth and differentiation factors, extracellular matrix components, proteases, membrane-bound receptors, and intracellular signaling molecules.
Why Use an Antibody Array to Detect Angiogenesis-Related Proteins?
Determining the expression of multiple cytokines in a single sample can be expensive, time consuming and can require specialized equipment. Performing multiple immunoprecipitations and Western blots requires time, labor, and reagents. The use of a multiplex antibody array to detect multiple cytokines in a single sample can be cost-effective and also save time and sample.
- 4 Array Membranes
- 4-Well Multi-dish
- Array Buffers
- Wash Buffer
- Detection Antibody Cocktail
- Streptavidin-HRP
- Chemiluminescent Detection Reagents
- Transparency Overlay Template
- Detailed Protocol
For a complete list of the kit contents and necessary materials, please see the Materials Provided/Other Supplies Required sections of the product datasheet.
Stability and Storage
Store the unopened kit at 2°C to 8°C. Do not use past kit expiration date.
Simultaneously detect the relative levels of these angiogenesis-related proteins in a single sample. | ||
ADAMTS1 | Endothelin-1 | NOV/CCN3/IGFBP-9 |
Amphiregulin | FGF acidic | Osteopontin |
Angiogenin | FGF basic | PD-ECGF |
Angiopoietin-1 | FGF-7/KGF | PDGF-AA |
Angiopoietin-3 | Fractalkine | PDGF-AB/BB |
CCL2/JE/MCP-1 | GM-CSF | Pentraxin-3 |
CCL3/MIP-1 alpha | HB-EGF | PlGF-2 |
CXCL1/KC | HGF | Prolactin |
CXCL10/IP-10/CRG-2 | IGFBP-1 | Proliferin |
CXCL12/SDF-1 | IGFBP-2 | Serpin E1/PAI-1 |
CXCL16 | IGFBP-3 | Serpin F1/PEDF |
CXCL4/PF4 | IL-1 alpha | Thrombospondin-2 |
Cyr61/CNN1/IGFBP-10 | IL-1 beta | TIMP-1 |
DLL4 | IL-10 | TIMP-4 |
DPPIV/CD26 | Leptin | Coagulation Factor III |
EGF | MMP-3 (pro and mature) | VEGF |
Endoglin/CD105 | MMP-8 (pro) | VEGF-B |
Endostatin/Collagen XVIII | MMP-9 (pro and active) |
Assays for analytes represented in the Mouse Angiogenesis Antibody Array Kit
Quantkine® ELISA kit | DuoSet® ELISA Development Reagents | |
ADAMTS1 | ||
Amphiregulin | DY989 | |
Angiogenin | ||
Angiopoietin-1 | ||
Angiopoietin-3 | MANL30 | DY738 |
CCL2/JE/MCP-1 | MJE00 | DY479 |
CCL3/MIP-1 alpha | MMA00 | DY450 |
CXCL1/KC | MKC00B | DY453 |
CXCL10/IP-10/CRG-2 | MCX100 | DY466 |
CXCL12/SDF-1 | MCX120 | DY460 |
CXCL16 | DY503 | |
CXCL4/PF4 | MCX400 | DY595 |
Cyr61/CNN1/IGFBP-10 | ||
DLL4 | DY1389 | |
DPPIV/CD26 | DY954 | |
EGF | MEG00 | DY2028 |
Endoglin/CD105 | MNDG00 | DY1320 |
Endostatin/Collagen XVIII | ||
Endothelin-1 | DET100 | |
FGF acidic | ||
FGF basic | ||
FGF-7/KGF | ||
Fractalkine | MCX310 | DY472 |
GM-CSF | MGM00 | DY415 |
HB-EGF | ||
HGF | MHG00 | DY2207 |
IGFBP-1 | ||
IGFBP-2 | DY797 | |
IGFBP-3 | MGB300 | DY775 |
IL-1 alpha | MLA00 | DY400 |
IL-1 beta | MLB00C | DY401 |
IL-10 | M1000B | DY417 |
Leptin | MOB00 | DY498 |
MMP-3 (pro and mature) | MMP300 | |
MMP-8 (pro) | ||
MMP-9 (pro and active) | MMPT90 | |
NOV/CCN3/IGFBP-9 | DY1976 | |
Osteopontin | MOST00 | DY441 |
PD-ECGF | ||
PDGF-AA | DAA00B | |
PDGF-AB/BB | MHD00/MBB00 | |
Pentraxin-3 | MPTX30 | DY2166 |
PlGF-2 | MP200 | DY465 |
Prolactin | DY1445 | |
Proliferin | ||
Serpin E1/PAI-1 | ||
Serpin F1/PEDF | ||
Thrombospondin-2 | ||
TIMP-1 | MTM100 | DY980 |
TIMP-4 | ||
Coagulation Factor III | ||
VEGF | MMV00 | DY493 |
VEGF-B | DY469 |
Specifications
Product Datasheets
Scientific Data
Multiple Proteins in TNF-alpha-treated Balb/3T3 Cells were Assessed using the Mouse Angiogenesis Array. A. The Proteome Profiler Mouse Angiogenesis Array Kit (Catalog # ARY015) was used to simultaneously assess the relative levels of 53 mouse angiogenesis-related proteins in cell lysates from Balb/3T3 mouse embryonic fibroblast cells that had been left untreated or treated with recombinant mouse TNF-alpha (Catalog # 410-MT) for 24 hours. B. Histogram profiles for select proteins were generated by quantifying the mean spot pixel density from the arrays using image software analysis. Green bars represent protein levels in lysates from untreated cells, purple bars represent protein levels in lysates from TNF-alpha-treated cells.
Citations for Proteome Profiler Mouse Angiogenesis Array Kit
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Tumor cell derived osteopontin and prostaglandin E2 synergistically promote the expansion of myeloid derived suppressor cells during the tumor immune escape phase
Authors: Mamand, DR;Bazaz, S;Mohammad, DK;Saher, O;Wiklander, OPB;Sadeghi, B;Hassan, M;El-Andaloussi, S;Abedi-Valugerdi, M;
International immunopharmacology 2024-02-15
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Urokinase-Type Plasminogen Activator Receptor Regulates Prosurvival and Angiogenic Properties of Cardiac Mesenchymal Stromal Cells
Authors: Dergilev, K;Tsokolaeva, Z;Goltseva, Y;Beloglazova, I;Ratner, E;Parfyonova, Y;
International journal of molecular sciences 2023-10-25
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Inhibiting the cytosolic function of CXXC5 accelerates diabetic wound healing by enhancing angiogenesis and skin repair
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Experimental & molecular medicine 2023-08-01
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Normal saline remodels the omentum and stimulates its receptivity for transcoelomic metastasis
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JCI insight 2023-06-22
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Defective extracellular matrix remodeling in brown adipose tissue is associated with fibro-inflammation and reduced diet-induced thermogenesis
Authors: Pellegrinelli, V;Figueroa-Juárez, E;Samuelson, I;U-Din, M;Rodriguez-Fdez, S;Virtue, S;Leggat, J;Çubuk, C;Peirce, VJ;Niemi, T;Campbell, M;Rodriguez-Cuenca, S;Blázquez, JD;Carobbio, S;Virtanen, KA;Vidal-Puig, A;
Cell reports 2023-06-13
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CD248 regulates Wnt signaling in pericytes to promote angiogenesis and tumor growth in lung cancer
Authors: CL Hong, IS Yu, CH Pai, JS Chen, MS Hsieh, HL Wu, SW Lin, HP Huang
Cancer Research, 2022-10-17;0(0):. 2022-10-17
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Pulmonary Thrombosis Promotes Tumorigenesis via Myeloid Hypoxia-Inducible Factors
Authors: X Lu, A Prodger, J Sim, CE Evans
Biomolecules, 2022-09-23;12(10):. 2022-09-23
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Stearoyl-CoA Desaturase Regulates Angiogenesis and Energy Metabolism in Ischemic Cardiomyocytes
Authors: AM Gan, Z Tracz-Gasz, A Ellert-Mik, VO Navrulin, JM Ntambi, P Dobrzyn
International Journal of Molecular Sciences, 2022-09-09;23(18):. 2022-09-09
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Macrophage-Specific, Mafb-Deficient Mice Showed Delayed Skin Wound Healing
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International Journal of Molecular Sciences, 2022-08-19;23(16):. 2022-08-19
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A stromal Integrated Stress Response activates perivascular cancer-associated fibroblasts to drive angiogenesis and tumour progression
Authors: II Verginadis, H Avgousti, J Monslow, G Skoufos, F Chinga, K Kim, NM Leli, IV Karagounis, BI Bell, A Velalopoul, CS Salinas, VS Wu, Y Li, J Ye, DA Scott, AL Osterman, A Sengupta, A Weljie, M Huang, D Zhang, Y Fan, E Radaelli, JW Tobias, F Rambow, P Karras, JC Marine, X Xu, AG Hatzigeorg, S Ryeom, JA Diehl, SY Fuchs, E Puré, C Koumenis
Nature Cell Biology, 2022-06-02;0(0):. 2022-06-02
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The ischemic time window of ectopic endometrial tissue crucially determines its ability to develop into endometriotic lesions
Authors: J Rudzitis-A, SI Huwer, C Scheuer, MD Menger, MW Laschke
Scientific Reports, 2022-04-04;12(1):5625. 2022-04-04
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Eicosanoid regulation of debris-stimulated metastasis
Authors: J Deng, H Yang, VM Haak, J Yang, FC Kipper, C Barksdale, SH Hwang, A Gartung, DR Bielenberg, S Subbian, KK Ho, X Ye, D Fan, Y Sun, BD Hammock, D Panigrahy
Proceedings of the National Academy of Sciences of the United States of America, 2021-10-12;118(41):. 2021-10-12
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DUOX2, a New Biomarker for Disseminated Gastric Cancer's Response to Low Dose Radiation in Mice
Authors: PR Parekh, E Solano-Gon, MB Martins, X Ma, K Tighe, A Casildo, A Zodda, C Johnstone, Y Poirier, J Mahmood, K Bhalla, S Li, RG Lapidus, F Carrier
Cancers, 2021-08-20;13(16):. 2021-08-20
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Three-Dimensional Vascularized Lung Cancer-on-a-Chip with Lung Extracellular Matrix Hydrogels for In Vitro Screening
Authors: S Park, TH Kim, SH Kim, S You, Y Jung
Cancers, 2021-08-05;13(16):. 2021-08-05
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Low RECK Expression Is Part of the Cervical Carcinogenesis Mechanisms
Authors: S Herbster, M Trombetta-, PT de Souza-S, A Paladino, CRF Silveira, MC Sogayar, LL Villa, AP Lepique, E Boccardo
Cancers, 2021-05-06;13(9):. 2021-05-06
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Persistent Airway Hyperresponsiveness Following Recovery from Infection with Pneumonia Virus of Mice
Authors: AR Limkar, CM Percopo, JL Redes, KM Druey, HF Rosenberg
Viruses, 2021-04-22;13(5):. 2021-04-22
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Seed- and Soil-Dependent Differences in Murine Breast Tumor Microenvironments Dictate Anti-PD-L1 IgG Delivery and Therapeutic Efficacy
Authors: YT Liu, S Goel, M Kai, JA Moran Guer, T Nguyen, J Mai, H Shen, A Ziemys, K Yokoi
Pharmaceutics, 2021-04-10;13(4):. 2021-04-10
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Osteoclasts protect bone blood vessels against senescence through the angiogenin/plexin-B2 axis
Authors: X Liu, Y Chai, G Liu, W Su, Q Guo, X Lv, P Gao, B Yu, G Ferbeyre, X Cao, M Wan
Nature Communications, 2021-03-23;12(1):1832. 2021-03-23
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Plasminogen regulates mesenchymal stem cell-mediated tissue repair after ischemia through Cyr61 activation
Authors: H Duan, Z He, M Lin, Y Wang, F Yang, RA Mitteer, HJ Kim, E Yeo, H Han, L Qin, Y Fan, Y Gong
JCI Insight, 2020-08-06;5(15):. 2020-08-06
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Loss of Osteopontin Expression Reduces HSV-1-Induced Corneal Opacity
Authors: A Filiberti, GB Gmyrek, ML Montgomery, R Sallack, DJJ Carr
Invest. Ophthalmol. Vis. Sci., 2020-08-03;61(10):24. 2020-08-03
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CNTF Prevents Development of Outer Retinal Neovascularization Through Upregulation of CxCl10
Authors: F Bucher, E Aguilar, KV Marra, J Rapp, J Arnold, S Diaz-Aguil, C Lange, H Agostini, G Schlunck, A Stahl, M Friedlande
Invest. Ophthalmol. Vis. Sci., 2020-08-03;61(10):20. 2020-08-03
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CD38 in cancer-associated fibroblasts promotes pro-tumoral activity
Authors: B Ben Baruch, E Mantsur, J Franco-Bar, E Blacher, E Cukierman, R Stein
Lab. Invest., 2020-07-01;0(0):. 2020-07-01
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Role of Insulin-Like Growth Factor Binding Protein-3 in the Pathogenesis of Herpes Stromal Keratitis
Authors: P Rao, PK Suvas, AD Jerome, JJ Steinle, S Suvas
Invest. Ophthalmol. Vis. Sci., 2020-02-07;61(2):46. 2020-02-07
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PLF-1 (Proliferin-1) Modulates Smooth Muscle Cell Proliferation and Development of Experimental Intimal Hyperplasia
Authors: L Hu, Z Huang, H Ishii, H Wu, S Suzuki, A Inoue, W Kim, H Jiang, X Li, E Zhu, L Piao, G Zhao, Y Lei, K Okumura, GP Shi, T Murohara, M Kuzuya, XW Cheng
J Am Heart Assoc, 2019-12-16;8(24):e005886. 2019-12-16
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Hearing impairment and associated morphological changes in pituitary adenylate cyclase activating polypeptide (PACAP)-deficient mice
Authors: DB Fulop, V Humli, J Szepesy, V Ott, D Reglodi, B Gaszner, A Nemeth, A Szirmai, L Tamas, H Hashimoto, T Zelles, A Tamas
Sci Rep, 2019-10-10;9(1):14598. 2019-10-10
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Intragenic antagonistic roles of protein and circRNA in tumorigenesis
Authors: J Guarnerio, Y Zhang, G Cheloni, R Panella, J Mae Katon, M Simpson, A Matsumoto, A Papa, C Loretelli, A Petri, S Kauppinen, C Garbutt, G Petur Niel, V Deshpande, M Castillo-M, C Cordon-Car, S Dimitrios, JG Clohessy, M Batish, PP Pandolfi
Cell Res., 2019-06-17;0(0):. 2019-06-17
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Deletion of calcineurin promotes a pro-tumorigenic fibroblast phenotype
Authors: A Lieberman, R Barrett, J Kim, KL Zhang, D Avery, J Monslow, H Kim, BJ Kim, E Pure, S Ryeom
Cancer Res., 2019-06-12;0(0):. 2019-06-12
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Metformin inhibits metastatic breast cancer progression and improves chemosensitivity by inducing vessel normalization via PDGF-B downregulation
Authors: JC Wang, GY Li, B Wang, SX Han, X Sun, YN Jiang, YW Shen, C Zhou, J Feng, SY Lu, JL Liu, MD Wang, PJ Liu
J. Exp. Clin. Cancer Res., 2019-06-04;38(1):235. 2019-06-04
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Targeting AU-rich element-mediated mRNA decay with a truncated active form of the zinc-finger protein TIS11b/BRF1 impairs major hallmarks of mammary tumorigenesis
Authors: F Rataj, S Planel, J Denis, C Roelants, O Filhol, L Guyon, JJ Feige, N Cherradi
Oncogene, 2019-03-26;0(0):. 2019-03-26
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A Transient Pseudosenescent Secretome Promotes Tumor Growth after Antiangiogenic Therapy Withdrawal
Authors: M Mastri, A Tracz, CR Lee, M Dolan, K Attwood, JG Christense, S Liu, JML Ebos
Cell Rep, 2018-12-26;25(13):3706-3720.e8. 2018-12-26
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A paradoxical method to enhance compensatory lung growth: Utilizing a VEGF inhibitor
Authors: DT Dao, L Anez-Busti, SS Jabbouri, A Pan, H Kishikawa, PD Mitchell, GL Fell, MA Baker, RS Watnick, H Chen, MS Rogers, DR Bielenberg, M Puder
PLoS ONE, 2018-12-19;13(12):e0208579. 2018-12-19
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Caspase-11 regulates the tumour suppressor function of STAT1 in a murine model of colitis-associated carcinogenesis
Authors: B Flood, J Manils, C Nulty, E Flis, S Kenealy, G Barber, J Fay, KHG Mills, EW Kay, EM Creagh
Oncogene, 2018-12-11;0(0):. 2018-12-11
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Adipocyte-secreted BMP8b mediates adrenergic-induced remodeling of the neuro-vascular network in adipose tissue
Authors: V Pellegrine, VJ Peirce, L Howard, S Virtue, D Türei, M Senzacqua, A Frontini, JW Dalley, AR Horton, G Bidault, I Severi, A Whittle, K Rahmouni, J Saez-Rodri, S Cinti, AM Davies, A Vidal-Puig
Nat Commun, 2018-11-26;9(1):4974. 2018-11-26
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The TRPC5 channel regulates angiogenesis and promotes recovery from ischemic injury in mice
Authors: Y Zhu, M Gao, T Zhou, M Xie, A Mao, L Feng, X Yao, WT Wong, X Ma
J. Biol. Chem., 2018-11-09;294(1):28-37. 2018-11-09
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Zika virus impairs the development of blood vessels in a mouse model of congenital infection
Authors: PP Garcez, HB Stolp, S Sravanam, RR Christoff, JCCG Ferreira, AA Dias, P Pezzuto, LM Higa, J Barbeito-A, RO Ferreira, CBV Andrade, M Siqueira, TMP Santos, J Drumond, A Hoerder-Su, CVF de Lima, F Tovar-Moll, RT Lopes, L Fragel-Mad, R Lent, TM Ortiga-Car, J Stipursky, M Bellio, A Tanuri, Z Molnár
Sci Rep, 2018-08-24;8(1):12774. 2018-08-24
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Decellularized Diaphragmatic Muscle Drives a Constructive Angiogenic Response In Vivo
Authors: ME Alvarèz Fa, M Piccoli, C Franzin, A Sgrò, A Dedja, L Urbani, E Bertin, C Trevisan, P Gamba, AJ Burns, P De Coppi, M Pozzobon
Int J Mol Sci, 2018-04-28;19(5):. 2018-04-28
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Late neuroprogenitors contribute to normal retinal vascular development in aHif2a-dependent manner
Authors: E Cristante, SE Liyanage, RD Sampson, A Kalargyrou, G De Rossi, M Rizzi, J Hoke, J Ribeiro, RN Maswood, Y Duran, T Matsuki, N Aghaizu, UF Luhmann, AJ Smith, RR Ali, JWB Bainbridge
Development, 2018-04-25;0(0):. 2018-04-25
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Mousetap, a Novel Technique to Collect Uncontaminated Vitreous or Aqueous and Expand Usefulness of Mouse Models
Authors: SD Fortmann, VE Lorenc, J Shen, SF Hackett, PA Campochiar
Sci Rep, 2018-04-23;8(1):6371. 2018-04-23
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Endothelial Progenitor Cell Secretome and Oligovascular Repair in a Mouse Model of Prolonged Cerebral Hypoperfusion
Authors: T Maki, A Morancho, P Martinez-S, K Hayakawa, H Takase, AC Liang, M Gabriel-Sa, E Medina-Gut, K Washida, J Montaner, J Lok, EH Lo, K Arai, A Rosell
Stroke, 2018-03-06;0(0):. 2018-03-06
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Multipotent Adult Progenitor Cells Support Lymphatic Regeneration at Multiple Anatomical Levels during Wound Healing and Lymphedema
Authors: M Beerens, XL Aranguren, B Hendrickx, W Dheedene, T Dresselaer, U Himmelreic, C Verfaillie, A Luttun
Sci Rep, 2018-03-01;8(1):3852. 2018-03-01
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Pituitary adenylate cyclase-activating polypeptide ameliorates vascular dysfunction induced by hyperglycaemia
Authors: M Solymar, I Ivic, M Balasko, BD Fulop, G Toth, A Tamas, G Reman, A Koller, D Reglodi
Diab Vasc Dis Res, 2018-02-21;0(0):1479164118757. 2018-02-21
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A non-cell-autonomous role for Pml in the maintenance of leukemia from the niche
Authors: J Guarnerio, LM Mendez, N Asada, AV Menon, J Fung, K Berry, PS Frenette, K Ito, PP Pandolfi
Nat Commun, 2018-01-04;9(1):66. 2018-01-04
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Fractalkine induces angiogenic potential in CX3CR1-expressing monocytes
Authors: Y Park, J Lee, JY Kwak, K Noh, E Yim, HK Kim, YJ Kim, HE Broxmeyer, JA Kim
J. Leukoc. Biol., 2017-12-28;0(0):. 2017-12-28
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Effects of collagen peptides intake on skin ageing and platelet release in chronologically aged mice revealed by cytokine array analysis
Authors: H Song, L Zhang, Y Luo, S Zhang, B Li
J. Cell. Mol. Med., 2017-09-18;0(0):. 2017-09-18
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Nuclear FAK and Runx1 cooperate to regulate IGFBP3, cell cycle progression and tumor growth
Authors: M Canel, A Byron, AH Sims, J Cartier, H Patel, MC Frame, VG Brunton, B Serrels, A Serrels
Cancer Res., 2017-08-14;0(0):. 2017-08-14
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Integrin ?3/Akt signaling contributes to platelet-induced hemangioendothelioma growth
Authors: R Gu, X Sun, Y Chi, Q Zhou, H Xiang, DB Bosco, X Lai, C Qin, KF So, Y Ren, XM Chen
Sci Rep, 2017-07-25;7(1):6455. 2017-07-25
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Mesenchymal stem cell carriers enhance antitumor efficacy of oncolytic adenoviruses in an immunocompetent mouse model
Authors: E Rincón, T Cejalvo, D Kanojia, A Alfranca, MÁ Rodríguez-, RAG Hoyos, Y Han, L Zhang, R Alemany, MS Lesniak, J García-Cas
Oncotarget, 2017-07-11;0(0):. 2017-07-11
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Downregulation of adaptor protein MyD88 compromises the angiogenic potential of B16 murine melanoma
Authors: LD Trucco, E Roselli, P Araya, NG Nuñez, HA Mena, JL Bocco, S Negrotto, M Maccioni
PLoS ONE, 2017-06-29;12(6):e0179897. 2017-06-29
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Mdivi-1 induced acute changes in the angiogenic profile after ischemia-reperfusion injury in female mice
Authors: S Veeranki, SC Tyagi
Physiol Rep, 2017-06-01;5(11):. 2017-06-01
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Regulatory T cells promote myelin regeneration in the central nervous system
Authors: Y Dombrowski, T O'Hagan, M Dittmer, R Penalva, SR Mayoral, P Bankhead, S Fleville, G Eleftheria, C Zhao, M Naughton, R Hassan, J Moffat, J Falconer, A Boyd, P Hamilton, IV Allen, A Kissenpfen, PN Moynagh, E Evergren, B Perbal, AC Williams, RJ Ingram, JR Chan, RJ Franklin, DC Fitzgerald
Nat. Neurosci, 2017-03-13;0(0):. 2017-03-13
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Inhibition of PHD3 by salidroside promotes neovascularization through cell-cell communications mediated by muscle-secreted angiogenic factors
Authors: J Zhang, V Kasim, YD Xie, C Huang, J Sisjayawan, A Dwi Ariyan, XS Yan, XY Wu, CP Liu, L Yang, M Miyagishi, SR Wu
Sci Rep, 2017-03-07;7(0):43935. 2017-03-07
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Autophagy gene ATG7 regulates ultraviolet radiation-induced inflammation and skin tumorigenesis
Authors: L Qiang, A Sample, CR Shea, K Soltani, KF Macleod, YY He
Autophagy, 2017-01-01;0(0):0. 2017-01-01
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High-fat Diet Enhances Mammary Tumorigenesis and Pulmonary Metastasis and Alters Inflammatory and Angiogenic Profiles in MMTV-PyMT Mice
Authors: Sneha Sundaram
Anticancer Res, 2016-12-01;36(12):6279-6287. 2016-12-01
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C-reactive protein can upregulate VEGF expression to promote ADSC-induced angiogenesis by activating HIF-1? via CD64/PI3k/Akt and MAPK/ERK signaling pathways
Stem Cell Res Ther, 2016-08-16;7(1):114. 2016-08-16
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Granulocytic myeloid-derived suppressor cells promote angiogenesis in the context of multiple myeloma
Oncotarget, 2016-06-21;7(25):37931-37943. 2016-06-21
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Targeting Serglycin Prevents Metastasis in Murine Mammary Carcinoma
PLoS ONE, 2016-05-25;11(5):e0156151. 2016-05-25
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Neutrophils suppress intraluminal NK-mediated tumor cell clearance and enhance extravasation of disseminated carcinoma cells
Authors: A Spiegel, MW Brooks, S Houshyar, F Reinhardt, M Ardolino, E Fessler, MB Chen, JA Krall, J DeCock, IK Zervantona, A Iannello, Y Iwamoto, V Cortez-Ret, RD Kamm, MJ Pittet, DH Raulet, RA Weinberg
Cancer Discov, 2016-04-12;0(0):. 2016-04-12
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FAK regulates platelet extravasation and tumor growth after antiangiogenic therapy withdrawal
Authors: M Haemmerle, J Bottsford-, S Pradeep, ML Taylor, HJ Choi, JM Hansen, HJ Dalton, RL Stone, MS Cho, AM Nick, AS Nagaraja, T Gutschner, KM Gharpure, LS Mangala, R Rupaimoole, HD Han, B Zand, GN Armaiz-Pen, SY Wu, CV Pecot, AR Burns, G Lopez-Bere
J Clin Invest, 2016-04-11;0(0):. 2016-04-11
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Wnt5a-Ror2 signaling in mesenchymal stem cells promotes proliferation of gastric cancer cells by activating CXCL16-CXCR6 axis.
Authors: Gosuke Takiguchi, Michiru Nishita, Kana Kurita, Yoshihiro Kakeji, Yasuhiro Minami
Cancer Science, 2016-02-09;0(0):1349-7006. 2016-02-09
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Monocyte Chemoattractant Protein-Induced Protein 1 (MCPIP1) Enhances Angiogenic and Cardiomyogenic Potential of Murine Bone Marrow-Derived Mesenchymal Stem Cells.
Authors: Labedz-Maslowska A, Lipert B, Berdecka D, Kedracka-Krok S, Jankowska U, Kamycka E, Sekula M, Madeja Z, Dawn B, Jura J, Zuba-Surma E
PLoS ONE, 2015-07-27;10(7):e0133746. 2015-07-27
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Lysophosphatidic acid alters the expression profiles of angiogenic factors, cytokines, and chemokines in mouse liver sinusoidal endothelial cells.
Authors: Chou C, Lai S, Ho C, Lin W, Chen C, Lee P, Peng F, Kuo S, Wu S, Lai H
PLoS ONE, 2015-03-30;10(3):e0122060. 2015-03-30
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Regional and stage-specific effects of prospectively purified vascular cells on the adult V-SVZ neural stem cell lineage.
Authors: Crouch E, Liu C, Silva-Vargas V, Doetsch F
J Neurosci, 2015-03-18;35(11):4528-39. 2015-03-18
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Application of VEGFA and FGF-9 enhances angiogenesis, osteogenesis and bone remodeling in type 2 diabetic long bone regeneration.
Authors: Wallner C, Schira J, Wagner J, Schulte M, Fischer S, Hirsch T, Richter W, Abraham S, Kneser U, Lehnhardt M, Behr B
PLoS ONE, 2015-03-05;10(3):e0118823. 2015-03-05
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Acellular lung scaffolds direct differentiation of endoderm to functional airway epithelial cells: requirement of matrix-bound HS proteoglycans.
Authors: Shojaie S, Ermini L, Ackerley C, Wang J, Chin S, Yeganeh B, Bilodeau M, Sambi M, Rogers I, Rossant J, Bear C, Post M
Stem Cell Reports, 2015-02-05;4(3):419-30. 2015-02-05
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F-box protein FBXW7 inhibits cancer metastasis in a non-cell-autonomous manner.
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Cessation of CCL2 inhibition accelerates breast cancer metastasis by promoting angiogenesis.
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Platelet secretion and hemostasis require syntaxin-binding protein STXBP5.
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J Clin Invest, 2014-09-17;124(10):4517-28. 2014-09-17
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Capillary force seeding of hydrogels for adipose-derived stem cell delivery in wounds.
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Pathophysiology of lung injury induced by common bile duct ligation in mice.
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TLR9 agonist regulates angiogenesis and inhibits corneal neovascularization.
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Lysyl oxidase-like 2 (LOXL2) and E47 EMT factor: novel partners in E-cadherin repression and early metastasis colonization.
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c-Met inhibition in a HOXA9/Meis1 model of CN-AML.
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Exosomes from retinal astrocytes contain antiangiogenic components that inhibit laser-induced choroidal neovascularization.
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ADAMTS4 and its proteolytic fragments differentially affect melanoma growth and angiogenesis in mice.
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Int J Cancer, 2013-02-12;133(2):294-306. 2013-02-12
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ADAMTS5 functions as an anti-angiogenic and anti-tumorigenic protein independent of its proteoglycanase activity.
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Differentiation state determines neural effects on microvascular endothelial cells.
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The synthetic triterpenoid CDDO-methyl ester delays estrogen receptor-negative mammary carcinogenesis in polyoma middle T mice.
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Vascular normalization by loss of Siah2 results in increased chemotherapeutic efficacy.
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Antimycotic ciclopirox olamine in the diabetic environment promotes angiogenesis and enhances wound healing.
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