Home / Active Degraders / PROTAC®(H-PGDS)-7

PROTAC®(H-PGDS)-7

Catalog #: 8004 Datasheet
Catalog # Availability Size / Price Qty
8004/5
PROTAC®(H-PGDS)-7 | CAS No. 2761281-50-7 | Active Degraders
1 Image
Description: Potent hematopoietic prostaglandin D2 synthase Degrader (PROTAC®)

Chemical Name: N-[4-[4-[[4-[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-1-piperazinyl]carbonyl]-1-piperidinyl]phenyl]-2-phenoxy-5-pyrimidinecarboxamide

Purity: ≥98%

Product Details
Reviews
Biological Activity Technical Data Additional Information Product Datasheets Calculators

Biological Activity

PROTAC®(H-PGDS)-7 is a potent Degrader of hematopoietic prostaglandin D2 synthase (H-PGDS; DC50 = 17pM after 24 hours). Comprises the H-PGDS inhibitor TFC-007 (Cat. No. 5108) directly linked to E3 ligase cereblon. Suppresses prostaglandin D2 production in vitro and in vivo.

PROTAC®(H-PGDS)-8 negative control (Cat. No. 8005) also available.

PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Technical Data

M.Wt:
742.79
Formula:
C40H38N8O7
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
2761281-50-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold under license from National Institute of Health Sciences, Japan and Tsuzuki Gakuen.

Product Datasheets

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for PROTAC®(H-PGDS)-7

There are currently no reviews for this product. Be the first to review PROTAC®(H-PGDS)-7 and earn rewards!

Have you used PROTAC®(H-PGDS)-7?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.