Pomalidomide 4'-PEG3-acid

Catalog #: 6681 Datasheet
Catalog # Availability Size / Price Qty
6681/25
Pomalidomide 4'-PEG3-acid | CAS No. 2138440-82-9 | Degrader Building Blocks
1 Image
Description: Cereblon ligand with PEG linker and terminal acid for onward chemistry
Alternative Names: Pomalidomide - linker 2

Chemical Name: 3-[2-[2-[2-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethoxy]ethoxy]ethoxy]propanoic acid

Purity: ≥95%

Product Details
Reviews

Biological Activity

Pomalidomide 4'-PEG3-acid is a functionalized cereblon ligand for PROTAC® research and development; incorporates an E3 ligase ligand plus a PEG3 linker with terminal carboxylic acid ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D.

This product has been recently renamed. The previous name for this product was Pomalidomide - linker 2

Please contact us for SD files of our available Degrader Building Blocks.

PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Usage Guidelines

This product is provided for use in onward chemistry. Suitable solvents can be used.

Technical Data

M.Wt:
477.46
Formula:
C22H27N3O9
Purity:
≥95%
Storage:
Store at -20°C
CAS No:
2138440-82-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Degradation of the BAF complex factor BRD9 by heterobifunctional ligands.
    Remillard et al.
    Angew.Chem.Int.Ed.Engl., 2017;56:5738

Product Datasheets

Or select another batch:
View Batch

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for Pomalidomide 4'-PEG3-acid

There are currently no reviews for this product. Be the first to review Pomalidomide 4'-PEG3-acid and earn rewards!

Have you used Pomalidomide 4'-PEG3-acid?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.