Pimonidazole
Chemical Name: α-[(2-Nitro-1H-imidazol-1-yl)methyl]-1-piperidineethanol
Purity: ≥98%
Biological Activity
Pimonidazole is a hypoxia detection reagent. Labels hypoxic tumor cells in vivo. Also labels hypoxic mesenchymal stem cells in mouse bone marrow.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Notch2 signaling regulates the proliferation of murine bone marrow-derived mesenchymal stem/stromal cells via c-Myc expression.
Sato et al.
PLoS One, 2016;11:e0165946 -
Orally administered pimonidazole to label hypoxic tumor cells.
Bennewith et al.
Cancer Res., 2002;62:6827
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