Photo-lenalidomide-acid
Chemical Name: (E)-2-(4-((2-(2,6-Dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)diazenyl)-2,6-dimethoxyphenoxy)acetic acid
Purity: ≥95%
Biological Activity
Photo-lenalidomide-acid is a functionalized cereblon ligand containing a dimethoxy azo-benzene photoswitch; for use as a precursor to photoswitchable Degraders (PHOTACs). Photo-lenalidomide-acid is supplied with a carboxylic acid functional handle for ready conjugation to a linker/target protein ligand. Part of a range of functionalized tool molecules for Degrader R&D.Usage Guidelines
This product is provided for use in onward chemistry. Suitable solvents can be used.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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PHOTACs enable optical control of protein degradation.
Reynders et al.
Sci.Adv., 2020;6:eaay5064
Product Datasheets
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