PD 4'-oxyacetic acid

Catalog #: 7858 Datasheet
Catalog # Availability Size / Price Qty
7858/50
PD 4'-oxyacetic acid | CAS No. 2633633-12-0 | Degrader Building Blocks
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Description: Functionalized cereblon ligand for PROTAC development

Chemical Name: 2-[4-(Tetrahydro-2,4-dioxo-1(2H)-pyrimidinyl)phenoxy]acetic acid

Purity: ≥95%

Product Details
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Biological Activity

PD 4'-oxyacetic is a carboxylic acid-functionalized cereblon ligand that can be used for PROTAC® Degrader development. The compound can be used to develop PD-PROTACs that exhibit improved stability and potency compared with PROTACs synthesized using IMiD (immunomodulatory imide drug) analogs.

Please contact us for SD files of our available Degrader Building Blocks.

PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Usage Guidelines

This product is provided for use in onward chemistry. Suitable solvents can be used.

Technical Data

M.Wt:
264.24
Formula:
C12H12N2O5
Purity:
≥95%
Storage:
Store at -20°C
CAS No:
2633633-12-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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