PD 334581
Chemical Name: N-[5-[3,4-Difluoro-2-[(2-fluoro-4-iodophenyl)amino]phenyl]-1,3,4-oxadiazol-2-yl]-4-morpholineethanamine
Purity: ≥98%
Biological Activity
PD 334581 is an inhibitor of MEK1. Analog of PD 184352 (Cat. No. 4237).Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Targeting cancer with small molecule kinase inhibitors.
Zhang et al.
Nat.Rev.Cancer, 2009;9:28 -
Structures of human MAP kinase kinase 1 (MEK1) and MEK2 describe novel competitive kinase inhibition.
Ohren et al.
Nat.Struct.Mol.Biol., 2004;11:1192
Product Datasheets
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