PD 334581

Catalog #: 4824 Datasheet
Catalog # Availability Size / Price Qty
4824/10
4824/50
PD 334581 | CAS No. 548756-68-9 | MEK Inhibitors
1 Image
Description: MEK1 inhibitor

Chemical Name: N-[5-[3,4-Difluoro-2-[(2-fluoro-4-iodophenyl)amino]phenyl]-1,3,4-oxadiazol-2-yl]-4-morpholineethanamine

Purity: ≥98%

Product Details
Reviews

Biological Activity

PD 334581 is an inhibitor of MEK1. Analog of PD 184352 (Cat. No. 4237).

Technical Data

M.Wt:
545.3
Formula:
C20H19F3IN5O2
Solubility:
Soluble to 100 mM in DMSO and to 10 mM in ethanol
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
548756-68-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Targeting cancer with small molecule kinase inhibitors.
    Zhang et al.
    Nat.Rev.Cancer, 2009;9:28
  2. Structures of human MAP kinase kinase 1 (MEK1) and MEK2 describe novel competitive kinase inhibition.
    Ohren et al.
    Nat.Struct.Mol.Biol., 2004;11:1192

Product Datasheets

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