pCPA methyl ester hydrochloride
Chemical Name: 4-Chloro-DL-Phenylalanine methyl ester hydrochloride
Purity: ≥98%
Biological Activity
pCPA methyl ester hydrochloride is a tryptophan hydroxylase inhibitor. Inhibits 5-HT synthesis. Depletes 5-HT levels in orbitofrontal cortex and impairs reversal learning in rats. Methyl ester of p-Chlorophenylalanine (Cat. No. 0938).Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Involvement of monoaminergic system in the antidepressant-like effect of (octylseleno)-xylofuranoside in the mouse tail suspension test.
Pinto Brod et al.
Prog.Neuropsychopharmacol.Biol.Psychiatry., 2016;65:201 -
Vort. restores reversal learning impaired by 5-HT depletion or chronic intermittent cold stress in rats.
Wallace et al.
Int.J.Neuropsychopharmacol., 2014;17:1695
Product Datasheets
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