Pancreatic Polypeptide (human)
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Description: NPY Y4 agonist; involved in gastrointestinal tract function
Purity: ≥95%
Biological Activity
Pancreatic Polypeptide (human) is an endogenous high affinity agonist for human NPY Y4 receptor (Ki = 0.056 nM). Believed to play an important role in the function of the gastrointestinal tract.Technical Data
M.Wt:
4181.7
Formula:
C185H287N53O54S2
Sequence:
APLEPVYPGDNATPEQMAQYAADLRRYINMLTRPRY
(Modification: Tyr-36 = C-terminal amide)
Solubility:
Soluble to 0.70 mg/ml in water
Purity:
≥95%
Storage:
Store at -20°C
CAS No:
75976-10-2
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
-
Cloning and functional expression of a human Y4 subtype receptor for pancreatic polypeptide, neuropeptide Y, and peptide YY.
Bard et al.
J.Biol.Chem., 1995;270:26762 -
Multiple receptors for the pancreatic polypeptide (PP-fold) family: physiological implications.
Gehlert
Proc.Soc.Exp.Biol.Med., 1998;218:7 -
XVI. International Union of Pharmacology recommendations for the nomenclature of neuropeptide Y, peptide YY, and pancreatic polypeptide receptors.
Michel et al.
Pharmacol.Rev., 1998;50:143
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For pancreatic cancer detection
By Ahmed Ali
on 07/16/2018
Good quality, I gave 4 stars because the delivery was without ice
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