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PA Janelia Fluor® 646, Maleimide

Catalog #: 8133 Datasheet
Catalog # Availability Size / Price Qty
8133/300U
PA Janelia Fluor® 646, Maleimide | Photoactivatable Dyes
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Description: Red photoactivatable dye (Reactive group: maleimide). Application: flow cytometry, confocal microscopy, super resolution microscopy including dSTORM & STED. Suitable for live cell imaging

Chemical Name: 3,7-Di(azetidin-1-yl)-2'-diazo-N-(2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethyl)-5,5-dimethyl-3'-oxo-2',3'-dihydro-5H-spiro[dibenzo[b,e]siline-10,1'-indene]-6'-carboxamide

Purity: ≥90%

Product Details
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Biological Activity Technical Data Additional Information Background Product Datasheets Calculators

Biological Activity

Key information: PA Janelia Fluor® 646, Maleimide is a red cell-permeable photoactivatable fluorescent dye; supplied with a maleimide reactive group for conjugation (thiol reactivity). Suitable for live and fixed cell imaging.

Application: Suitable for flow cytometry, confocal microscopy, super resolution microscopy (SRM) including dSTORM (in both live and fixed cells) and STED.

Properties and Photophysical Data: Excitation and emission maxima (λ) are 649 - 651 nm and 663 - 665 nm, respectively.

Please see the product protocol for further information and a guide to protein/antibody labeling.

Janelia Fluor is a registered trademark of Howard Hughes Medical Institute.

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Technical Data

M.Wt:
642.79
Formula:
C36H34N6O4Si
Solubility:
Soluble to 10 mM in DMSO
Purity:
≥90%
Storage:
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus

Background References

  1. Bright photoactivatable fluorophores for single-molecule imaging.
    Grimm et al.
    Nat.Methods, 2016;13:985

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