O8 OGG1 Inhibitor
Chemical Name: 3,4-Dichlorobenzo[b]thiophene-2-carbohydrazide
Purity: ≥98%
Biological Activity
O8 OGG1 Inhibitor is a potent and selective 8-oxoguanine DNA glycosylase 1 (OGG1) inhibitor (IC50 = 0.2 μM in a gel based assay). Exhibits > 200-fold selectivity for OGG1 over other DNA glycosylases, NEIL1 and NTH1.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Small molecule inhibitors of 8-oxoguanine DNA glycosylase-1 (OGG1).
Donley et al.
ACS Chem.Biol., 2015;10:2334
Product Datasheets
Citation for O8 OGG1 Inhibitor
The citations listed below are publications that use Tocris products. Selected citations for O8 OGG1 Inhibitor include:
1 Citation: Showing 1 - 1
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Ginkgolic Acid Inhibits Coronavirus Strain 229E Infection of Human Epithelial Lung Cells.
Authors: Gustavo F Et al.
Pharmaceuticals (Basel) 2021;14
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