NMDA

Transient Oxygen/Glucose Deprivation Causes a Delayed Loss of Mitochondria and Increases Spontaneous Calcium Signaling in Astrocytic Processes.
Authors: O'Donnell Et al.
J Neurosci  2016;36:7109

Activation of calcineurin underlies altered trafficking of α2 subunit containing GABAA receptors during prolonged epileptiform activity.
Authors: Eckel Et al.
Neuropharmacology  2015;88:82

Conformations of tissue plasminogen activator (tPA) orchestrate neuronal survival by a crosstalk between EGFR and NMDAR.
Authors: Bertrand Et al.
Cell Death Dis  2015;6:e1924

Brain ischemia downregulates the neuroprotective GDNF-Ret signaling by a calpain-dependent mechanism in cultured hippocampal neurons.
Authors: Curcio Et al.
Cell Death Dis  2015;6:e1645

The higher order auditory cortex is involved in the assignment of affective value to sensory stimuli.
Authors: Grosso Et al.
Nat Commun  2015;6:8886

Neuronal development is promoted by weakened intrinsic antioxidant defences due to epigenetic repression of Nrf2.
Authors: Bell Et al.
Nat Commun  2015;6:7066

The ON:OFF switch, σ1R-HINT1 protein, controls GPCR-NMDA receptor cross-regulation: implications in neurological disorders.
Authors: Rodríguez-Muñoz Et al.
Oncotarget  2015;6:35458

Nitric oxide targets oligodendrocytes and promotes their morphological differentiation.
Authors: Garthwaite Et al.
Glia  2015;63:383

Impact of subanesthetic doses of KA on AMPA-mediated responses in rats: An in vivo electrophysiological study on monoaminergic and glutamatergic neurons.
Authors: Iskandrani Et al.
J Psychopharmacol  2015;29:792

CaMKII mediates recruitment and activation of the deubiquitinase CYLD at the postsynaptic density.
Authors: Thein Et al.
PLoS One  2014;9:e91312

Neuritin can normalize neural deficits of Alzheimer's disease.
Authors: An Et al.
Cell Death Dis  2014;5:e1523

KA alters cortical integration of GABAergic interneurons and induces long-term sex-dependent impairments in transgenic Gad67-GFP mice.
Authors: Aligny Et al.
Cell Death Dis  2014;5:e1311

Presynaptic GABAergic inhibition regulated by BDNF contributes to neuropathic pain induction.
Authors: Chen Et al.
Nat Commun  2014;5:5331

IKK regulates the deubiquitinase CYLD at the postsynaptic density.
Authors: Thein Et al.
Biochem Biophys Res Commun  2014;450:550

STAT1 negatively regulates spatial memory formation and mediates the memory-impairing effect of Aβ.
Authors: Hsu Et al.
Neuropsychopharmacology  2014;39:746

Long-term depression-inducing stimuli promote cleavage of the synaptic adhesion molecule NGL-3 through NMDA receptors, matrix metalloproteinases and presenilin/γ-secretase.
Authors: Lee Et al.
Philos Trans R Soc Lond B Biol Sci  2014;369:20130158

Rapid and reversible knockdown of endogenous proteins by peptide-directed lysosomal degradation.
Authors: Fan Et al.
Nat Neurosci  2014;17:471

The calcium-sensitive σ-1 receptor prevents cannabinoids from provoking glutamate NMDA receptor hypofunction: implications in antinociception and psychotic diseases.
Authors: Sánchez-Blázquez Et al.
Int J Neuropsychopharmacol  2014;17:1943

PICK1 links Argonaute 2 to endosomes in neuronal dendrites and regulates miRNA activity.
Authors: Antoniou Et al.
EMBO Rep  2014;15:548

Camkii-mediated phosphorylation regulates distributions of Syngap-α1 and -α2 at the postsynaptic density.
Authors: Yang Et al.
PLoS One  2013;8:e71795

Evidence for glutamate as a neuroglial transmitter within sensory ganglia.
Authors: Kung Et al.
PLoS One  2013;8:e68312

Membrane potential measurements of isolated neurons using a voltage-sensitive dye.
Authors: Fairless Et al.
PLoS One  2013;8:e58260

Activation of group I metabotropic glutamate receptors potentiates heteromeric kainate receptors.
Authors: Rojas Et al.
Mol Pharmacol  2013;83:106

HINT1 protein cooperates with cannabinoid 1 receptor to negatively regulate glutamate NMDA receptor activity.
Authors: Vicente-Sánchez Et al.
Mol Brain  2013;6:42

Central activation of the A1 adenosine receptor (A1AR) induces a hypothermic, torpor-like state in the rat.
Authors: Tupone Et al.
J Neurosci  2013;33:14512

An essential role for inhibitor-2 regulation of protein phosphatase-1 in synaptic scaling.
Authors: Siddoway Et al.
J Neurosci  2013;33:11206

On the selectivity of neuronal NOS inhibitors.
Authors: Pigott Et al.
Br J Pharmacol  2013;168:1255

Physiological release of endogenous tau is stimulated by neuronal activity.
Authors: Pooler Et al.
EMBO Rep  2013;14:389

S-nitrosylation of AMPA receptor GluA1 regulates phosphorylation, single-channel conductance, and endocytosis.
Authors: Selvakumar Et al.
Proc Natl Acad Sci U S A  2013;110:1077

Gephyrin-independent GABA(A)R mobility and clustering during plasticity.
Authors: Niwa Et al.
PLoS One  2012;7:e36148

Glutamate may be an efferent transmitter that elicits inhibition in mouse taste buds.
Authors: Huang Et al.
PLoS One  2012;7:e30662

Molecular pharmacology of human NMDA receptors.
Authors: Hedegaard Et al.
Neurochem Int  2012;61:601

Metabotropic glutamate receptor 5 mediates phosphorylation of vascular endothelial cadherin and nuclear localization of β-catenin in response to homocysteine.
Authors: Beard Et al.
Vascul Pharmacol  2012;56:159

Glissandi: transient fast electrocorticographic oscillations of steadily increasing frequency, explained by temporally increasing gap junction conductance.
Authors: Cunningham Et al.
Epilepsia  2012;53:1205

In vivo comparison of harmine efficacy against psychostimulants: preferential inhibition of the cocaine response through a glutamatergic mechanism.
Authors: Owaisat Et al.
Neurosci Lett  2012;525:12

Bidirectional control of mRNA translation and synaptic plasticity by the cytoplasmic polyadenylation complex.
Authors: Udagawa Et al.
Mol Cell  2012;47:253

Glutamate carboxypeptidase II (GCPII) inhibitor displays anti-glutamate and anti-cocaine effects in an invertebrate assay.
Authors: Tallarida Et al.
Amino Acids  2012;42:2521

The mu-opioid receptor and the NMDA receptor associate in PAG neurons: implications in pain control.
Authors: Rodríguez-Muñoz Et al.
Neuropsychopharmacology  2012;37:338

Reducing amyloid-related Alzheimer's disease pathogenesis by a small molecule targeting filamin A.
Authors: Wang Et al.
J Neurosci  2012;32:9773

Glutamate controls tPA recycling by astrocytes, which in turn influences glutamatergic signals.
Authors: Cassé Et al.
J Neurosci  2012;32:5186

Genetic deletion of TNF receptor suppresses excitatory synaptic transmission via reducing AMPA receptor synaptic localization in cortical neurons.
Authors: He Et al.
FASEB J  2012;26:334

Neuroprotective effects of phenolic antioxidant tBHQ associate with inhibition of FoxO3a nuclear translocation and activity.
Authors: Bahia Et al.
J Neurochem  2012;123:182

Soybean-derived Bowman-Birk inhibitor inhibits neurotoxicity of LPS-activated macrophages.
Authors: Li Et al.
J Neuroinflammation  2011;8:15

Microglial morphology and dynamic behavior is regulated by ionotropic glutamatergic and GABAergic neurotransmission.
Authors: Fontainhas Et al.
PLoS One  2011;6:e15973

Functional role of neurotrophin-3 in synapse regeneration by spiral ganglion neurons on inner hair cells after excitotoxic trauma in vitro.
Authors: Wang and Green
J Neurosci  2011;31:7938

Activity-dependent ubiquitination of the AMPA receptor subunit GluA2.
Authors: Lussier Et al.
J Neurosci  2011;31:3077

SynGAP moves out of the core of the postsynaptic density upon depolarization.
Authors: Yang Et al.
Neuroscience  2011;192:132

Exposure of neurons to excitotoxic levels of glutamate induces cleavage of the RNA editing enzyme, adenosine deaminase acting on RNA 2, and loss of GLUR2 editing.
Authors: Mahajan Et al.
Neuroscience  2011;189:305

VEGF modulates NMDA receptors activity in cerebellar granule cells through Src-family kinases before synapse formation.
Authors: Meissirel Et al.
Proc Natl Acad Sci U S A  2011;108:13782

CB1 modulation of temporally distinct synaptic facilitation among local circuit interneurons mediated by N-type calcium channels in CA1.
Authors: Ali
J Neurophysiol  2011;105:1051

Neuroprotective effect of inhaled nitric oxide on excitotoxic-induced brain damage in neonatal rat.
Authors: Pansiot Et al.
PLoS One  2010;5:e10916

Calcium binding to PICK1 is essential for the intracellular retention of AMPA receptors underlying long-term depression.
Authors: Citri Et al.
J Neurosci  2010;30:16437

Sustained glutamate receptor activation down-regulates GABAB receptors by shifting the balance from recycling to lysosomal degradation.
Authors: Maier Et al.
J Biol Chem  2010;285:35606

NR2D-containing NMDA receptors mediate tissue plasminogen activator-promoted neuronal excitotoxicity.
Authors: Baron Et al.
Cell Death Differ  2010;17:860

Oligodendrocytes are damaged by neuromyelitis optica immunoglobulin G via astrocyte injury.
Authors: Marignier Et al.
Brain  2010;133:2578

Disassembly of shank and homer synaptic clusters is driven by soluble beta-amyloid(1-40) through divergent NMDAR-dependent signalling pathways.
Authors: Roselli Et al.
PLoS One  2009;4:e6011

N-MthD.-aspartate receptor- and metabotropic glutamate receptor-dependent long-term depression are differentially regulated by the ubiquitin-proteasome system.
Authors: Citri Et al.
Eur J Neurosci  2009;30:1443

Cortical adenylyl cyclase 1 is required for thalamocortical synapse maturation and aspects of layer IV barrel development.
Authors: Iwasato Et al.
J Neurosci  2008;28:5931

A quantitative assessment of glutamate uptake into hippocampal synaptic terminals and astrocytes: new insights into a neuronal role for excitatory amino acid transporter 2 (EAAT2).
Authors: Furness Et al.
Neuroscience  2008;157:80

An activity-regulated microRNA controls dendritic plasticity by down-regulating p250GAP.
Authors: Wayman Et al.
Proc Natl Acad Sci U S A  2008;105:9093

AMPAR exocytosis through NO modulation of PICK1.
Authors: Sossa Et al.
Neuropharmacology  2007;53:92

Differential redistribution of native AMPA receptor complexes following LTD induction in acute hippocampal slices.
Authors: Holman Et al.
Neuropharmacology  2007;52:92

Synaptic scaffolding molecule alpha is a scaffold to mediate N-MthD.-aspartate receptor-dependent RhoA activation in dendrites.
Authors: Iida Et al.
Mol Cell Biol  2007;27:4388

NMDA receptor activation potentiates inhibitory transmission through GABA receptor-associated protein-dependent exocytosis of GABA(A) receptors.
Authors: Marsden Et al.
J Neurosci  2007;27:14326

Characterization of the role of microtubule-associated protein 1B in metabotropic glutamate receptor-mediated endocytosis of AMPA receptors in hippocampus.
Authors: Davidkova and Carroll
J Neurosci  2007;27:13273

Vesicular release of glutamate from unmyelinated axons in white matter.
Authors: Ziskin Et al.
Nat Neurosci  2007;10:321

Activation of group III metabotropic glutamate receptors attenuates rotenone toxicity on DArgic neurons through a microtubule-dependent mechanism.
Authors: Jiang Et al.
J Neurosci  2006;26:4318

cAMP-dependent protein kinase postsynaptic localization regulated by NMDA receptor activation through translocation of an A-kinase anchoring protein scaffold protein.
Authors: Smith Et al.
J Neurosci  2006;26:2391

Analgesia mediated by the TRPM8 cold receptor in chronic neuropathic pain.
Authors: Proudfoot Et al.
Curr Biol  2006;16:1591

Glutamatergic regulation of the p70S6 kinase in primary mouse neurons.
Authors: Lenz and Avruch
J Biol Chem  2005;280:38121

Akt-dependent expression of NAIP-1 protects neurons against amyloid-{beta} toxicity.
Authors: Lesne Et al.
J Biol Chem  2005;280:24941

Behavioral stress enhances hippocampal CA1 long-term depression through the blockade of the glutamate uptake.
Authors: Yang Et al.
J Neurosci  2005;25:4288

Diminished neuronal activity increases neuron-neuron connectivity underlying silent synapse formation and the rapid conversion of silent to functional synapses.
Authors: Nakayama Et al.
J Neurosci  2005;25:4040

Neuroprotective activity of the mGluR5 antagonists MPEP and MTEP against acute excitotoxicity differs and does not reflect actions at mGluR5 receptors.
Authors: Lea Et al.
Br J Pharmacol  2005;145:527

beta-OE, dehydroepiandrosterone, and dehydroepiandrosterone sulfate protect against N-MthD.-aspartate-induced neurotoxicity in rat hippocampal neurons by different mechanisms.
Authors: Kurata Et al.
J Pharmacol Exp Ther  2004;311:237

Cell type-specific interleukin-1beta signaling in the CNS.
Authors: Srinivasan Et al.
J Neurosci  2004;24:6482

Subpallial origin of a population of projecting pioneer neurons during corticogenesis.
Authors: Morante-Oria Et al.
Proc Natl Acad Sci U S A  2003;100:12468

Presynaptic N-MthD.-aspartate receptors at the parallel fiber-Purkinje cell synapse.
Authors: Casado Et al.
Proc Natl Acad Sci U S A  2000;97:11593

Investigations into the mechanism of action of the new anticonvulsant retigabine. Interaction with GABAergic and glutamatergic neurotransmission and with voltage gated ion channels.
Authors: Rundfeldt
Arzneimittelforschung  2000;50:1063

Selective mGluR5 antagonists MPEP and SIB-1893 decrease NMDA or glutamate-mediated neuronal toxicity through actions that reflect NMDA receptor antagonism.
Authors: O'Leary Et al.
Br J Pharmacol  2000;131:1429

In vivo microdialysis study of a specific inhibitor of soluble guanylyl cyclase on the glutamate receptor/nitric oxide/cyclic GMP pathway.
Authors: Fedele Et al.
Br J Pharmacol  1996;119:590