Nicotinamide

Biological Activity

Nicotinamide synthesized to Ancillary Material Grade also available.

For more information about how Nicotinamide may be used, see our protocol:

Technical Data

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

1. Organoid Models of Human and Mouse Ductal Pancreatic Cancer.
   Boj SF, Hwang C, Baker LA et al.
   Cell.
2. Nicotinamide rescues human embryonic stem cell-derived neuroectoderm from parthanatic cell death.
   Cimadamore et al.
   Stem Cells., 2009;27:1772
3. A modified method of Ins producing cells' generation from bone marrow-derived mesenchymal stem cells.
   Czubak et al.
   J.Diabetes Res., 2014;2014:628591
4. Protective effect of nicotinamide against poly(ADP-ribose) polymerase-1-mediated astrocyte death depends on its transporter-mediated uptake.
   Suzuki et al.
   Life.Sci., 2010;86:676
5. SnapShot: Growing Organoids from Stem Cells.
   Sato et al.
   Cell, 2015;161:1700
6. In vitro expansion of human gastric epithelial stem cells and their responses to bacterial infection.
   Bartfeld et al.
   Gastroenterology, 2015;148:126
7. Isolation and in vitro expansion of human colonic stem cells.
   Jung et al.
   Nat.Med., 2011;17:1227

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