Neurokinin B (human, porcine)
Purity: ≥95%
Biological Activity
Neurokinin B (human, porcine) is an endogenous tachykinin agonist peptide that shows preference for the NK3 receptor (EC50 = 1 nM).Technical Data
(Modifications: Met-10 = C-terminal amide)
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Neurokinin B is a preferred agonist for a neuronal substance P receptor and its action is antagonized by enkephalin.
Laufer et al.
Proc.Natl.Acad.Sci.U.S.A., 1985;82:7444 -
The tachykinin peptide family.
Severini et al.
Pharmacol.Rev., 2002;54:285 -
Neurokinin B potentiates ATP-activated currents in rat DRG neurons.
Wang et al.
Brain Res., 2001;923:157
Product Datasheets
Citation for Neurokinin B (human, porcine)
The citations listed below are publications that use Tocris products. Selected citations for Neurokinin B (human, porcine) include:
1 Citation: Showing 1 - 1
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Evidence That Dynorphin Acts Upon KNDy and GnRH Neurons During GnRH Pulse Termination in the Ewe.
Authors: Weems Et al.
Endocrinology 2018;159:3187
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