Naspm trihydrochloride

Biological Activity

Technical Data

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

1. SynGAP regulates protein synthesis and homeostatic synaptic plasticity in developing cortical networks.
   Wang C, Held R, Hall B
   PLoS ONE, 2013;8(12):e83941.
2. Re-silencing of silent synapses unmasks anti-relapse effects of environmental enrichment
   YY Ma, X Wang, Y Huang, H Marie, EJ Nestler, OM Schlüter, Y Dong
   Proc Natl Acad Sci USA, 2016;0(0):.
3. A subtype-selective, use-dependent inhibitor of native AMPA receptors.
   Nilsen and England
   J.Am.Chem.Soc., 2007;129:4902
4. Effects of spider toxin and its analogue on glutamate-activated currents in the hippocampal CA1 neuron after ischaemia.
   Tsubokawa et al.
   J.Neurophysiol., 1995;74:218
5. Blocking effect of 1-naphthyl acetyl spermine on Ca²⁺-permeable AMPA receptors in cultured rat hippocampal neurons.
   Koike et al.
   Neurosci.Res., 1997;29:27
6. Blockade of calcium-permeable AMPA receptors protects hippocampal neurons against global ischemia-induced death.
   Noh et al.
   Proc.Natl.Acad.Sci.USA, 2005;102:12230
7. Slow AMPA receptors in hippocampal principal cells
   NP Pampaloni, I Riva, AL Carbone, AJR Plested
   Cell Reports, 2021;36(5):109496.

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