Mpro 61

Catalog #: 7695 Datasheet

Catalog #	Availability	Size / Price	Qty
7695/5

Mpro 61 | CAS No. 2679814-93-6 | 3C and 3CL Protease Inhibitors

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Description: Potent non-covalent inhibitor of SARS-CoV-2 main protease

Chemical Name: 5-[5-[3-Chloro-5-[(2-chlorophenyl)methoxy]-4-fluorophenyl]-6-oxo[1(6H),3'-bipyridin]-3-yl]-1-methyl-2,4(1H,3H)-pyrimidinedione

Purity: ≥95%

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Product Details

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Biological Activity Technical Data Additional Information Product Datasheets Calculators

Biological Activity

Mpro 61 is a potent non-covalent inhibitor of SARS-CoV-2 main protease (IC₅₀ = 44 nM, EC₅₀ = 0.175 μM in the replicon assay and EC₅₀ = 0.08 μM in the infectious SARS-CoV-2 assay); it is cell permable and exhibits no apparent cytotoxicity.

Technical Data

M.Wt:

565.38

Formula:

C₂₈H₁₉Cl₂FN₄O₄

Solubility:

Soluble to 20 mM in DMSO

Purity:

≥95%

Storage:

Store at -20°C

CAS No:

2679814-93-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:

Sold under license from Yale University. U.S. patent application number 63/135,062.

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