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Mouse S100A11 Alexa Fluor® 350-conjugated Antibody

Catalog #: FAB5167U Datasheet
Catalog # Availability Size / Price Qty
FAB5167U-100UG
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Mouse S100A11 Alexa Fluor® 350-conjugated Antibody Summary

Species Reactivity
Mouse
Specificity
Detects mouse S100A11 in direct ELISAs and Western blots. In direct ELISAs, ;no cross-reactivity with recombinant mouse S100A1, 4, 6, 8, 9, 10, 13, or 16 is observed, and approximately 75% cross‑reactivity with recombinant human (rh) S100A11 is observed.
Source
Monoclonal Rat IgG2a Clone # 493804
Purification
Protein A or G purified
Immunogen
E. coli-derived recombinant mouse S100A11
Met1-Ile98
Accession # P50543
Formulation
Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide
Label
Alexa Fluor 350 (Excitation= 346 nm, Emission= 442 nm)

Applications

Recommended Concentration
Sample
Western Blot
Optimal dilution of this antibody should be experimentally determined.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: S100A11

S100A11, also called calgizzarin or S100C, is an antiproliferative 10 kDa protein that is a member of the S100 family of EF-hand calcium binding proteins. It is found in the cytosol of proliferating fibroblasts and keratinocytes, but in the nucleus in differentiating cells. TGF-beta treatment or calcium-induced S100A11 serine phosphorylation induces nuclear translocation of S100A11 and subsequent growth inhibition in normal cells. The 98 amino acid (aa) mouse S100A11 shares 82% and 94% aa identity with human and rat S100A11, respectively.

Long Name
S100 Calcium Binding Protein A11
Entrez Gene IDs
6282 (Human); 20195 (Mouse); 445415 (Rat)
Alternate Names
Calgizzarin; Metastatic lymph node gene 70 protein; MLN 70; MLN70; protein S100-A11; Protein S100-C; S100 calcium binding protein A11; S100 calcium-binding protein A11 (calgizzarin); S100 calcium-binding protein A11; S100A11; S100C; S100CS100 calcium binding protein A11 (calgizzarin)

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