Mouse/Rat MyD88 Alexa Fluor® 405-conjugated Antibody

Catalog #: AF3109V Datasheet

Catalog #	Availability	Size / Price	Qty
AF3109V-100UG

All MyD88 Antibodies

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Mouse/Rat MyD88 Alexa Fluor® 405-conjugated Antibody Summary

Species Reactivity

Mouse, Rat

Specificity

Detects mouse and rat MyD88 in Western blots.

Source

Polyclonal Goat IgG

Purification

Antigen Affinity-purified

Immunogen

E. coli-derived recombinant mouse MyD88
Met1-Pro296
Accession # Q3U7M4

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 405 (Excitation= 405 nm, Emission= 421 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

CyTOF-ready

Optimal dilution of this antibody should be experimentally determined.

Immunocytochemistry

Optimal dilution of this antibody should be experimentally determined.

Intracellular Staining by Flow Cytometry

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: MyD88

Myeloid Differentiation primary response protein 88 (MyD88) is a 296 amino acid, 34 kDa, ubiquitously expressed, cytoplasmic adaptor protein involved in the signaling of TLR and IL-1 R family members. MyD88 contains an N-terminal death domain and a C-terminal Toll/IL-1 R (TIR) domain. Each domain seems to participate in protein-protein interactions, as the death domain is inactive. Upon Toll receptor ligation, MyD88 is recruited to the receptor and initiates a signaling cascade that results in NK kappa B and JNK activation. The amino acid sequence of mouse MyD88 is 93% identical to that of rat MyD88.

Long Name

Myeloid Differentiation Primary Response Gene 88

Entrez Gene IDs

4615 (Human); 17874 (Mouse)

Alternate Names

MyD88; MYD88D; myeloid differentiation primary response gene (88); myeloid differentiation primary response protein MyD88