Mouse RARRES1 Alexa Fluor® 750-conjugated Antibody

Catalog #: AF4657S Datasheet

Catalog #	Availability	Size / Price	Qty
AF4657S-100UG

All RARRES1 Antibodies

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Mouse RARRES1 Alexa Fluor® 750-conjugated Antibody Summary

Species Reactivity

Mouse

Specificity

Detects mouse RARRES1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 1% cross-reactivity with recombinant human RARRES1 is observed.

Source

Polyclonal Goat IgG

Purification

Antigen Affinity-purified

Immunogen

E. coli-derived recombinant mouse RARRES1
Pro42-Phe283
Accession # F6ZIS7

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 750 (Excitation= 749 nm, Emission= 775 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: RARRES1

RARRES1 (retinoic acid receptor responder 1; also Tig1) is a member of the protease inhibitor I47 family of proteins. It is expressed in epithelium, including keratinocytes, plus prostate and breast epithelium. It is considered to be a tumor-suppressor molecule, presumably acting as an inhibitor of carboxypeptidase A. Mouse RARRES1 is 283 amino acids (aa) in length. Based on human, it is a type II transmembrane (TM) protein with a TM segment at, or near, aa 75‑95. Over
aa 42-283, mouse RARRES1 shares 85% and 74% aa identity with rat and human RARRES1, respectively.

Long Name

Retinoic Acid Receptor Responder [Tazarotene-induced] 1

Entrez Gene IDs

5918 (Human); 109222 (Mouse); 310486 (Rat)

Alternate Names

RARRES1; RAR-responsive protein TIG1; retinoic acid receptor responder (tazarotene induced) 1; retinoic acid receptor responder protein 1; TIG1; TIG1Tazarotene-induced gene 1 protein

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