Mouse p53 Alexa Fluor® 488-conjugated Antibody

Applications

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Preparation and Storage

Background: p53

The p53 tumor suppressor protein is a multi-functional transcription factor that regulates cellular decisions regarding proliferation, cell cycle checkpoints, and apoptosis. The importance of p53 is underscored by its mutation in over 50% of human cancers. Mice that lack one or both copies of p53 also showed an increased incidence of tumors, which makes the p53 deficient mouse a model system for studying cancer generation and progression.

Product Datasheets

Related Research Areas

• Apoptosis Transcription Factors and Regulators
• Cancer Biomarkers
• Cancer Stem Cell Transcription Factors
• Cell Cycle
• Checkpoint
• DNA Damage and Repair
• Epithelial Stem Cell Transcription Factors
• Hematopoietic Stem Cell Transcription Factors and Regulators
• Immunoglobulin-Like Domain Transcription Factors
• Mesenchymal Stem Cell Transcription Factors
• Neural Stem Cell Transcription Factors
• p53 Pathway
• Parkinson's Disease Related Molecules
• Pluripotent Stem Cell Transcription Factors
• TNF Superfamily Regulators
• Transcription Factors and Regulators
• Transcription Factors in the Akt Pathway