Mouse Lipocalin-2/NGAL DuoSet ELISA Summary
* Provided that the recommended microplates, buffers, diluents, substrates and solutions are used, and the assay is run as summarized in the Assay Procedure provided.
This DuoSet ELISA Development kit contains the basic components required for the development of sandwich ELISAs to measure natural and recombinant mouse Lipocalin-2. The suggested diluent is suitable for the analysis of most cell culture supernate, serum, and plasma samples. Diluents for complex matrices, such as serum and plasma, should be evaluated prior to use in this DuoSet.
Product Features
- Optimized capture and detection antibody pairings with recommended concentrations save lengthy development time
- Development protocols are provided to guide further assay optimization
- Assay can be customized to your specific needs
- Economical alternative to complete kits
Kit Content
- Capture Antibody
- Detection Antibody
- Recombinant Standard
- Streptavidin conjugated to horseradish-peroxidase (Streptavidin-HRP)
Other Reagents Required
DuoSet Ancillary Reagent Kit 2 (5 plates): (Catalog # DY008) containing 96 well microplates, plate sealers, substrate solution, stop solution, plate coating buffer (PBS), wash buffer, and Reagent Diluent Concentrate 2.
The components listed above may be purchased separately:
PBS: (Catalog # DY006), or 137 mM NaCl, 2.7 mM KCl, 8.1 mM Na2HPO4, 1.5 mM KH2PO4, pH 7.2 - 7.4, 0.2 µm filtered
Wash Buffer: (Catalog # WA126), or 0.05% Tween® 20 in PBS, pH 7.2-7.4
Reagent Diluent: (Catalog # DY995), or 1% BSA in PBS, pH 7.2-7.4, 0.2 µm filtered
Substrate Solution: 1:1 mixture of Color Reagent A (H2O2) and Color Reagent B (Tetramethylbenzidine) (Catalog # DY999)
Stop Solution: 2 N H2SO4 (Catalog # DY994)
Microplates: R&D Systems (Catalog # DY990)
Plate Sealers: ELISA Plate Sealers (Catalog # DY992)
Scientific Data
Product Datasheets
Preparation and Storage
Background: Lipocalin-2/NGAL
The Lipocalin family comprises a diverse group of mostly secreted soluble proteins that bind hydrophobic ligands and act as transporters, carrying small molecules to specific cells. Lipocalins are related by possessing an 8-stranded beta-barrel structure. Lipocalin-1, also named tear lipocalin (TL), von Ebners gland protein (VEG) and tear pre-albumin, binds a large number of hydrophobic molecules and exhibits cysteine proteinase inhibitor and endonuclear activities. Lipocalin-2, also known as neutrophil gelatinase-associated lipocalin (NGAL), is a component of granules in neutrophils from tissues that are normally exposed to microorganisms and is upregulated during inflammation. Lipocalin-2 can form homodimers and can heterodimerize with the neutrophil gelatinase MMP-9.
Assay Procedure
GENERAL ELISA PROTOCOL
Plate Preparation
- Dilute the Capture Antibody to the working concentration in PBS without carrier protein. Immediately coat a 96-well microplate with 100 μL per well of the diluted Capture Antibody. Seal the plate and incubate overnight at room temperature.
- Aspirate each well and wash with Wash Buffer, repeating the process two times for a total of three washes. Wash by filling each well with Wash Buffer (400 μL) using a squirt bottle, manifold dispenser, or autowasher. Complete removal of liquid at each step is essential for good performance. After the last wash, remove any remaining Wash Buffer by aspirating or by inverting the plate and blotting it against clean paper towels.
- Block plates by adding 300 μL Reagent Diluent to each well. Incubate at room temperature for a minimum of 1 hour.
- Repeat the aspiration/wash as in step 2. The plates are now ready for sample addition.
Assay Procedure
- Add 100 μL of sample or standards in Reagent Diluent, or an appropriate diluent, per well. Cover with an adhesive strip and incubate 2 hours at room temperature.
- Repeat the aspiration/wash as in step 2 of Plate Preparation.
- Add 100 μL of the Detection Antibody, diluted in Reagent Diluent, to each well. Cover with a new adhesive strip and incubate 2 hours at room temperature.
- Repeat the aspiration/wash as in step 2 of Plate Preparation.
- Add 100 μL of the working dilution of Streptavidin-HRP to each well. Cover the plate and incubate for 20 minutes at room temperature. Avoid placing the plate in direct light.
- Repeat the aspiration/wash as in step 2.
- Add 100 μL of Substrate Solution to each well. Incubate for 20 minutes at room temperature. Avoid placing the plate in direct light.
- Add 50 μL of Stop Solution to each well. Gently tap the plate to ensure thorough mixing.
- Determine the optical density of each well immediately, using a microplate reader set to 450 nm. If wavelength correction is available, set to 540 nm or 570 nm. If wavelength correction is not available, subtract readings at 540 nm or 570 nm from the readings at 450 nm. This subtraction will correct for optical imperfections in the plate. Readings made directly at 450 nm without correction may be higher and less accurate.
Citations for Mouse Lipocalin-2/NGAL DuoSet ELISA
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Select gut microbiota impede rotavirus vaccine efficacy
Authors: Ngo, VL;Wang, Y;Wang, Y;Shi, Z;Britton, R;Zou, J;Ramani, S;Jiang, B;Gewirtz, AT;
Cellular and molecular gastroenterology and hepatology
Species: Mouse
Sample Types: Serum
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Salmonella Typhimurium exploits host polyamines for assembly of the type 3 secretion machinery
Authors: Miki, T;Uemura, T;Kinoshita, M;Ami, Y;Ito, M;Okada, N;Furuchi, T;Kurihara, S;Haneda, T;Minamino, T;Kim, YG;
PLoS biology
Species: Mouse
Sample Types: Fecal Extracts
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Remote organ cancer adversely alters renal function and induces kidney injury, inflammation, and fibrosis
Authors: Hammouri, D;Orwick, A;Doll, M;Vega, DS;Shah, PP;Clarke, CJ;Clem, B;Beverly, LJ;Siskind, LJ;
bioRxiv : the preprint server for biology
Species: Mouse
Sample Types: Plasma
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Harnessing intestinal tryptophan catabolism to relieve atherosclerosis in mice
Authors: Chajadine, M;Laurans, L;Radecke, T;Mouttoulingam, N;Al-Rifai, R;Bacquer, E;Delaroque, C;Rytter, H;Bredon, M;Knosp, C;Vilar, J;Fontaine, C;Suffee, N;Vandestienne, M;Esposito, B;Dairou, J;Launay, JM;Callebert, J;Tedgui, A;Ait-Oufella, H;Sokol, H;Chassaing, B;Taleb, S;
Nature communications
Species: Mouse
Sample Types: Feces
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Gut microbial factors predict disease severity in a mouse model of multiple sclerosis
Authors: Steimle, A;Neumann, M;Grant, ET;Willieme, S;De Sciscio, A;Parrish, A;Ollert, M;Miyauchi, E;Soga, T;Fukuda, S;Ohno, H;Desai, MS;
Nature microbiology
Species: Transgenic Mouse
Sample Types: Fecal Extract
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Preclinical and clinical evidence of the association of colibactin-producing Escherichia coli with anxiety and depression in colon cancer
Authors: Rondepierre, F;Meynier, M;Gagniere, J;Deneuvy, V;Deneuvy, A;Roche, G;Baudu, E;Pereira, B;Bonnet, R;Barnich, N;Carvalho, FA;Pezet, D;Bonnet, M;Jalenques, I;
World journal of gastroenterology
Species: Mouse
Sample Types: Fecal Extract
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Commensal E. coli limits Salmonella gut invasion during inflammation by producing toxin-bound siderophores in a tonB-dependent manner
Authors: Cherrak, Y;Salazar, MA;Yilmaz, K;Kreuzer, M;Hardt, WD;
PLoS biology
Species: Mouse
Sample Types: Feces
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Further Evaluation of Enterohemorrhagic Escherichia coli Gold Nanoparticle Vaccines Utilizing Citrobacter rodentium as the Model Organism
Authors: Bowser, S;Melton-Celsa, A;Chapartegui-González, I;Torres, AG;
Vaccines
Species: Mouse
Sample Types: Feces
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Neutrophils and NADPH Oxidases Are Major Contributors to Mild but Not Severe Ischemic Acute Kidney Injury in Mice
Authors: Révész, C;Kaucsár, T;Godó, M;Bocskai, K;Krenács, T;Mócsai, A;Szénási, G;Hamar, P;
International journal of molecular sciences
Species: Mouse
Sample Types: Plasma
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Time resolved multi-omics reveals diverse metabolic strategies of Salmonella during diet-induced inflammation
Authors: Kokkinias, K;Sabag-Daigle, A;Kim, Y;Leleiwi, I;Shaffer, M;Kevorkian, R;Daly, RA;Wysocki, VH;Borton, MA;Ahmer, BMM;Wrighton, KC;
bioRxiv : the preprint server for biology
Species: Mouse
Sample Types: Feces
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Evaluating the Effects of Chronic Oral Exposure to the Food Additive Silicon Dioxide on Oral Tolerance Induction and Food Sensitivities in Mice
Authors: Lamas, B;Martins Breyner, N;Malaisé, Y;Wulczynski, M;Galipeau, HJ;Gaultier, E;Cartier, C;Verdu, EF;Houdeau, E;
Environmental health perspectives
Species: Mouse
Sample Types: Cell Culture Supernates
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Optogenetic activation of cholinergic enteric neurons reduces inflammation in experimental colitis
Authors: Rahman, AA;Stavely, R;Pan, W;Ott, L;Ohishi, K;Ohkura, T;Han, C;Hotta, R;Goldstein, AM;
Cellular and molecular gastroenterology and hepatology
Species: Mouse
Sample Types: Fecal Extract
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Inflammatory Bowel Disease Increases the Severity of Myocardial Infarction after Acute Ischemia-Reperfusion Injury in Mice
Authors: Mami, W;Znaidi-Marzouki, S;Doghri, R;Ben Ahmed, M;Znaidi, S;Messadi, E;
Biomedicines
Species: Mouse
Sample Types: Feces
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Suppression of epithelial proliferation and tumorigenesis by immunoglobulin A
Authors: Donaldson, GP;Reis, GL;Saad, M;Mamede, I;Chen, G;DelGaudio, NL;Zhang, D;Aydin, B;Harrer, CE;Castro, TB;Grivennikov, S;Reis, BS;Stadtmueller, BM;Victora, GD;Mucida, D;
bioRxiv : the preprint server for biology
Species: Transgenic Mouse
Sample Types: Feces
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Prevention of Colitis-Associated Cancer via Oral Administration of M13-Loaded Lipid Nanoparticles
Authors: Long, D;Alghoul, Z;Sung, J;Yang, C;Merlin, D;
Pharmaceutics
Species: Mouse
Sample Types: Feces
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Akkermansia muciniphila exacerbates food allergy in fibre-deprived mice
Authors: Parrish, A;Boudaud, M;Grant, ET;Willieme, S;Neumann, M;Wolter, M;Craig, SZ;De Sciscio, A;Cosma, A;Hunewald, O;Ollert, M;Desai, MS;
Nature microbiology
Species: Mouse
Sample Types: Fecal Supernates
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Neutrophil metalloproteinase driven spleen damage hampers infection control of trypanosomiasis
Authors: Pham, HTT;Magez, S;Choi, B;Baatar, B;Jung, J;Radwanska, M;
Nature communications
Species: Mouse
Sample Types: Plasma, Tissue Homogenates
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Vaccination against microbiota motility protects mice from the detrimental impact of dietary emulsifier consumption
Authors: Kordahi, MC;Delaroque, C;Bredèche, MF;Gewirtz, AT;Chassaing, B;
PLoS biology
Species: Mouse
Sample Types: Feces
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Nutritional and host environments determine community ecology and keystone species in a synthetic gut bacterial community
Authors: Weiss, AS;Niedermeier, LS;von Strempel, A;Burrichter, AG;Ring, D;Meng, C;Kleigrewe, K;Lincetto, C;Hübner, J;Stecher, B;
Nature communications
Species: Mouse
Sample Types: Feces
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Bacteriophages targeting protective commensals impair resistance against Salmonella Typhimurium infection in gnotobiotic mice
Authors: von Strempel, A;Weiss, AS;Wittmann, J;Salvado Silva, M;Ring, D;Wortmann, E;Clavel, T;Debarbieux, L;Kleigrewe, K;Stecher, B;
PLoS pathogens
Species: Mouse
Sample Types: Feces
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Effects of Probiotics on Colitis-Induced Exacerbation of Alzheimer's Disease in AppNL-G-F Mice
Authors: Sahu, B;Johnson, LM;Sohrabi, M;Usatii, AA;Craig, RMJ;Kaelberer, JB;Chandrasekaran, SP;Kaur, H;Nookala, S;Combs, CK;
International journal of molecular sciences
Species: Mouse
Sample Types: Cell Culture Supernates
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Indoleamine 2,3-dioxygenase 1 regulates cell permissivity to astrovirus infection
Authors: Cortez, V;Livingston, B;Sharp, B;Hargest, V;Papizan, JB;Pedicino, N;Lanning, S;Vaughn Jordan, S;Gulman, J;Vogel, P;DuBois, RM;Chase Crawford, J;Boyd, DF;Pruett-Miller, SM;Thomas, PG;Schultz-Cherry, S;
Mucosal immunology
Species: Mouse
Sample Types: Feces
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IL-36/IL-36R Signaling Promotes CD4+ T Cell-Dependent Colitis via Pro-Inflammatory Cytokine Production
Authors: Maarouf, M;Kuczma, M;Denning, TL;
bioRxiv : the preprint server for biology
Species: Mouse
Sample Types: Fecal Supernates
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Gasdermin D independent canonical inflammasome responses cooperate with caspase-8 to establish host defense against gastrointestinal Citrobacter rodentium infection
Authors: E Eeckhout, L Hamerlinck, V Jonckheere, P Van Damme, G van Loo, A Wullaert
Cell Death & Disease, 2023-04-21;14(4):282.
Species: Mouse
Sample Types: Feces
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ATG16L1 protects from interferon-gamma-induced cell death in the small intestinal crypt
Authors: EG Foerster, DKL Tsang, S Goyal, SJ Robertson, LM Robert, H Maughan, CJ Streutker, SE Girardin, DJ Philpott
Mucosal Immunology, 2023-02-14;0(0):.
Species: Transgenic Mouse
Sample Types: Serum
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Antimicrobial overproduction sustains intestinal inflammation by inhibiting Enterococcus colonization
Authors: KK Jang, T Heaney, M London, Y Ding, F Yeung, D Ercelen, YH Chen, J Axelrad, S Gurunathan, A Marijke Ke, ME Griffin, HC Hang, K Cadwell
bioRxiv : the preprint server for biology, 2023-02-01;0(0):.
Species: Mouse
Sample Types: Stool Supernates
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Chemotaxis and autoinducer-2 signalling mediate colonization and contribute to co-existence of Escherichia coli strains in the murine gut
Authors: L Laganenka, JW Lee, L Malferthei, CL Dieterich, L Fuchs, J Piel, C von Mering, V Sourjik, WD Hardt
Nature Microbiology, 2023-01-09;0(0):.
Species: Mouse
Sample Types: Feces
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Chronic gut inflammation impairs contextual control of fear
Authors: CE Matisz, M Patel, NS Hong, RJ McDonald, AJ Gruber
Scientific Reports, 2022-11-29;12(1):20586.
Species: Mouse
Sample Types: Feces
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Impact of Dextran-Sodium-Sulfate-Induced Enteritis on Murine Cytomegalovirus Reactivation
Authors: A Jentzer, S Fauteux-Da, P Verhoeven, A Cantais, MY Novoa, F Jospin, B Chanut, N Rochereau, T Bourlet, X Roblin, B Pozzetto, S Pillet
Viruses, 2022-11-22;14(12):.
Species: Mouse
Sample Types: Fecal Supernates
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Serpin-positive Bifidobacterium breve CNCM I-5644 improves intestinal permeability in two models of irritable bowel syndrome
Authors: E Torres-Mar, S Holowacz, J Delannoy, L Lenoir, E Jacouton, S Gervason, M Meynier, AS Boucard, FA Carvalho, F Barbut, LG Bermúdez-H, P Langella, AJ Waligora-D
Scientific Reports, 2022-11-17;12(1):19776.
Species: Mouse
Sample Types: Fecal Supernates
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Agr2-associated ER stress promotes adherent-invasive E.�coli dysbiosis and triggers CD103+ dendritic cell IL-23-dependent ileocolitis
Authors: M Viladomiu, M Khounlotha, B Dogan, SF Lima, A Elsaadi, E Cardakli, JG Castellano, C Ng, J Herzog, AA Schoenborn, M Ellermann, B Liu, S Zhang, AS Gulati, RB Sartor, KW Simpson, SM Lipkin, RS Longman
Cell Reports, 2022-11-15;41(7):111637.
Species: Transgenic Mouse
Sample Types: Feces
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Variant APOL1 protein in plasma associates with larger particles in humans and mouse models of kidney injury
Authors: M Andrews, T Yoshida, CM Henderson, H Pflaum, A McGregor, JA Lieberman, IH de Boer, T Vaisar, J Himmelfarb, B Kestenbaum, JY Chung, SM Hewitt, BA Santo, B Ginley, P Sarder, AZ Rosenberg, T Murakami, JB Kopp, Z Kuklenyik, AN Hoofnagle
PLoS ONE, 2022-10-24;17(10):e0276649.
Species: Transgenic Mouse
Sample Types: Urine
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Pro-inflammatory megakaryocyte gene expression in murine models of breast cancer
Authors: HG Roweth, MW Malloy, GJ Goreczny, IC Becker, Q Guo, EA Mittendorf, JE Italiano, SS McAllister, EM Battinelli
Science Advances, 2022-10-12;8(41):eabo5224.
Species: Mouse
Sample Types: Plasma
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Anti-infective bile acids bind and inactivate a Salmonella virulence regulator
Authors: X Yang, KR Stein, HC Hang
Nature Chemical Biology, 2022-09-29;0(0):.
Species: Mouse
Sample Types: Feces
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IL-23 signaling prevents ferroptosis-driven renal immunopathology during candidiasis
Authors: N Millet, NV Solis, D Aguilar, MS Lionakis, RT Wheeler, N Jendzjowsk, M Swidergall
Nature Communications, 2022-09-22;13(1):5545.
Species: Mouse
Sample Types: Serum
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Intestinal effect of faba bean fractions in WD-fed mice treated with low dose of DSS
Authors: D Papoutsis, SDC Rocha, AM Herfindal, S Kjølsrud B, H Carlsen
PLoS ONE, 2022-08-08;17(8):e0272288.
Species: Mouse
Sample Types: Fecal Extracts
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Iron deficient diets modify the gut microbiome and reduce the severity of enteric infection in a mouse model of S. Typhimurium-induced enterocolitis
Authors: JR Ippolito, BD Piccolo, MS Robeson, DE Barney, J Ali, P Singh, SR Hennigar
The Journal of nutritional biochemistry, 2022-05-21;0(0):109065.
Species: Mouse
Sample Types: Plasma
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Aryl hydrocarbon receptor signals in epithelial cells govern the recruitment and location of Helios+ Tregs in the gut
Authors: Y Yoshimatsu, T Sujino, K Miyamoto, Y Harada, S Tanemoto, K Ono, S Umeda, K Yoshida, T Teratani, T Suzuki, Y Mikami, N Nakamoto, N Sasaki, K Takabayash, N Hosoe, H Ogata, K Sawada, T Imamura, A Yoshimura, T Kanai
Cell Reports, 2022-05-10;39(6):110773.
Species: Mouse
Sample Types:
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The expression of virulence genes increases membrane permeability and sensitivity to envelope stress in Salmonella Typhimurium
Authors: M Sobota, PN Rodilla Ra, A Cambré, A Rocker, J Mortier, T Gervais, T Haas, D Cornillet, D Chauvin, I Hug, T Julou, A Aertsen, M Diard
PloS Biology, 2022-04-07;20(4):e3001608.
Species: Mouse
Sample Types: Fecal
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Neutral ceramidase-dependent regulation of macrophage metabolism directs intestinal immune homeostasis and controls enteric infection
Authors: R Sun, X Gu, C Lei, L Chen, S Chu, G Xu, MA Doll, Y Tan, W Feng, L Siskind, CJ McClain, Z Deng
Cell Reports, 2022-03-29;38(13):110560.
Species: Mouse
Sample Types: Cell Culture Supernates
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Development of spirulina for the manufacture and oral delivery of protein therapeutics
Authors: BW Jester, H Zhao, M Gewe, T Adame, L Perruzza, DT Bolick, J Agosti, N Khuong, R Kuestner, C Gamble, K Cruickshan, J Ferrara, R Lim, T Paddock, C Brady, S Ertel, M Zhang, A Pollock, J Lee, J Xiong, M Tasch, T Saveria, D Doughty, J Marshall, D Carrieri, L Goetsch, J Dang, N Sanjaya, D Fletcher, A Martinez, B Kaldis, K Sigmar, E Afreen, T Nguyen, A Randolph, A Taber, A Krzeszowsk, B Robinett, DB Volkin, F Grassi, R Guerrant, R Takeuchi, B Finrow, C Behnke, J Roberts
Nature Biotechnology, 2022-03-21;0(0):.
Species: Mouse
Sample Types: Fecal Supernates
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Colitis-associated microbiota drives changes in behaviour in male mice in the absence of inflammation
Authors: FA Vicentini, JC Szamosi, L Rossi, L Griffin, K Nieves, D Bihan, IA Lewis, QJ Pittman, MG Swain, MG Surette, SA Hirota, KA Sharkey
Brain, Behavior, and Immunity, 2022-03-05;102(0):266-278.
Species: Mouse
Sample Types: Cell Culture Supernates
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Intestinal Epithelial AMPK Deficiency Causes Delayed Colonic Epithelial Repair in DSS-Induced Colitis
Authors: S Olivier, H Diounou, C Pochard, L Frechin, E Durieu, M Foretz, M Neunlist, M Rolli-Derk, B Viollet
Cells, 2022-02-09;11(4):.
Species: Mouse
Sample Types: Feces
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Multi-omics analyses of the ulcerative colitis gut microbiome link Bacteroides vulgatus proteases with disease severity
Authors: RH Mills, PS Dulai, Y Vázquez-Ba, C Sauceda, N Daniel, RR Gerner, LE Batachari, M Malfavon, Q Zhu, K Weldon, G Humphrey, M Carrillo-T, LD Goldasich, M Bryant, M Raffatellu, RA Quinn, AT Gewirtz, B Chassaing, H Chu, WJ Sandborn, PC Dorrestein, R Knight, DJ Gonzalez
Nature Microbiology, 2022-01-27;7(2):262-276.
Species: Mouse
Sample Types: Fecal Supernates
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Closely related Salmonella Derby strains triggered distinct gut microbiota alteration
Authors: X Yuan, H Xue, X Xu, X Jiao, Z Pan, Y Zhang
Gut pathogens, 2022-01-25;14(1):6.
Species: Mouse
Sample Types: Serum
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Kidney tubule iron loading in experimental focal segmental glomerulosclerosis
Authors: RPL van Swelm, S Beurskens, H Dijkman, ETG Wiegerinck, R Roelofs, F Thévenod, J van der Vl, JFM Wetzels, DW Swinkels, B Smeets
Scientific Reports, 2022-01-24;12(1):1199.
Species: Mouse
Sample Types: Urine
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Streptozotocin-induced hyperglycemia alters the cecal metabolome and exacerbates antibiotic-induced dysbiosis
Authors: JI Wurster, RL Peterson, CE Brown, S Penumutchu, DV Guzior, K Neugebauer, WH Sano, MM Sebastian, RA Quinn, P Belenky
Cell Reports, 2021-12-14;37(11):110113.
Species: Mouse
Sample Types: Feces
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Psychological stress impairs IL22-driven protective gut mucosal immunity against colonising pathobionts
Authors: CR Shaler, AA Parco, W Elhenawy, J Dourka, J Jury, EF Verdu, BK Coombes
Nature Communications, 2021-11-18;12(1):6664.
Species: Mouse
Sample Types: Tissue Homogenates
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Tofacitinib-Induced Modulation of Intestinal Adaptive and Innate Immunity and Factors Driving Cellular and Systemic Pharmacokinetics
Authors: B Texler, A Zollner, V Reinstadle, SJ Reider, S Macheiner, B Jelusic, A Pfister, C Watschinge, N Przysiecki, H Tilg, H Oberacher, AR Moschen
Cellular and Molecular Gastroenterology and Hepatology, 2021-10-06;0(0):.
Species: Mouse
Sample Types: Feces
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Citrobacter amalonaticus Inhibits the Growth of Citrobacter rodentium in the Gut Lumen
Authors: C Mullineaux, D Carson, EGD Hopkins, I Glegola-Ma, A Escobar-Ze, HP Browne, TD Lawley, G Frankel
MBio, 2021-10-05;12(5):e0241021.
Species: Mouse
Sample Types: Feces
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mTOR signaling mediates ILC3-driven immunopathology
Authors: C Teufel, E Horvath, A Peter, C Ercan, S Piscuoglio, MN Hall, D Finke, FM Lehmann
Mucosal Immunology, 2021-08-02;0(0):.
Species: Mouse
Sample Types: Fecal Supernates
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Geographic differences in gut microbiota composition impact susceptibility to enteric infection
Authors: AM Porras, Q Shi, H Zhou, R Callahan, G Montenegro, N Solomons, IL Brito
Cell Reports, 2021-07-27;36(4):109457.
Species: Mouse
Sample Types: Stool Supernates
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Gut microbiota signatures are associated with toxicity to combined CTLA-4 and PD-1 blockade
Authors: MC Andrews, CPM Duong, V Gopalakris, V Iebba, WS Chen, L Derosa, MAW Khan, AP Cogdill, MG White, MC Wong, G Ferrere, A Fluckiger, MP Roberti, P Opolon, MT Alou, S Yonekura, W Roh, CN Spencer, IF Curbelo, L Vence, A Reuben, S Johnson, R Arora, G Morad, M Lastrapes, EN Baruch, L Little, C Gumbs, ZA Cooper, PA Prieto, K Wani, AJ Lazar, MT Tetzlaff, CW Hudgens, MK Callahan, M Adamow, MA Postow, CE Ariyan, PO Gaudreau, L Nezi, D Raoult, C Mihalcioiu, A Elkrief, RC Pezo, LE Haydu, JM Simon, HA Tawbi, J McQuade, P Hwu, WJ Hwu, RN Amaria, EM Burton, SE Woodman, S Watowich, A Diab, SP Patel, IC Glitza, MK Wong, L Zhao, J Zhang, NJ Ajami, J Petrosino, RR Jenq, MA Davies, JE Gershenwal, PA Futreal, P Sharma, JP Allison, B Routy, L Zitvogel, JA Wargo
Nature Medicine, 2021-07-08;0(0):.
Species: Mouse
Sample Types: Fecal Supernates
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Chronic cerebral lipocalin 2 exposure elicits hippocampal neuronal dysfunction and cognitive impairment
Authors: B Olson, X Zhu, MA Norgard, P Diba, PR Levasseur, AC Buenafe, C Huisman, KG Burfeind, KA Michaelis, G Kong, T Braun, DL Marks
Brain, Behavior, and Immunity, 2021-07-08;0(0):.
Species: Mouse
Sample Types: CSF
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Heteropolysaccharides from S. cerevisiae show anti-adhesive properties against E. coli associated with Crohn's disease
Authors: A Sivignon, SY Yu, N Ballet, P Vandekerck, N Barnich, Y Guerardel
Carbohydrate polymers, 2021-07-08;271(0):118415.
Species: Mouse
Sample Types: Fecal Supernates
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NLRP3 Triggers Attenuate Lipocalin-2 Expression Independent with Inflammasome Activation
Authors: H Ahn, G Lee, J Kim, J Park, SG Kang, SI Yoon, E Lee, GS Lee
Cells, 2021-07-02;10(7):.
Species: Mouse
Sample Types: Cell Lysates
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Intestinal Inflammation and Altered Gut Microbiota Associated with Inflammatory Bowel Disease Render Mice Susceptible to Clostridioides difficile Colonization and Infection
Authors: L Abernathy-, MR Barron, JM George, MG Dieterle, KC Vendrov, IL Bergin, VB Young
MBio, 2021-06-15;0(0):e0273320.
Species: Mouse
Sample Types: Feces
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Amino Acid-Based Diet Prevents Lethal Infectious Diarrhea by Maintaining Body Water Balance in a Murine Citrobacter rodentium Infection Model
Authors: T Kimizuka, N Seki, G Yamaguchi, M Akiyama, S Higashi, K Hase, YG Kim
Nutrients, 2021-05-31;13(6):.
Species: Mouse
Sample Types: Feces
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Lipocalin 2 mediates appetite suppression during pancreatic cancer cachexia
Authors: B Olson, X Zhu, MA Norgard, PR Levasseur, JT Butler, A Buenafe, KG Burfeind, KA Michaelis, KR Pelz, H Mendez, J Edwards, SM Krasnow, AJ Grossberg, DL Marks
Nature Communications, 2021-04-06;12(1):2057.
Species: Mouse
Sample Types: Plasma
-
Western-style diet impedes colonization and clearance of Citrobacter rodentium
Authors: J An, X Zhao, Y Wang, J Noriega, AT Gewirtz, J Zou
PloS Pathogens, 2021-04-05;17(4):e1009497.
Species: Mouse
Sample Types: Fecal Supernates
-
Consumption of Select Dietary Emulsifiers Exacerbates the Development of Spontaneous Intestinal Adenoma
Authors: E Viennois, B Chassaing
International Journal of Molecular Sciences, 2021-03-05;22(5):.
Species: Mouse
Sample Types: Faecal supernates
-
Deletion of intestinal epithelial AMP-activated protein kinase alters distal colon permeability but not glucose homeostasis
Authors: S Olivier, C Pochard, H Diounou, V Castillo, J Divoux, J Alcantara, J Leclerc, S Guilmeau, C Huet, W Charifi, TV Varin, N Daniel, M Foretz, M Neunlist, BL Salomon, P Ghosh, A Marette, M Rolli-Derk, B Viollet
Molecular Metabolism, 2021-02-04;47(0):101183.
Species: Mouse
Sample Types: Fecal
-
The impact of dextran sodium sulphate and probiotic pre-treatment in a murine model of Parkinson's disease
Authors: Z Dwyer, M Chaiquin, J Landrigan, K Ayoub, P Shail, J Rocha, CL Childers, KB Storey, DJ Philpott, H Sun, S Hayley
Journal of Neuroinflammation, 2021-01-09;18(1):20.
Species: Mouse
Sample Types: Plasma
-
TNF Receptor 1 Promotes Early-Life Immunity and Protects against Colitis in Mice
Authors: CY Liu, SS Tam, Y Huang, PE Dubé, R Alhosh, N Girish, S Punit, S Nataneli, F Li, JM Bender, MK Washington, DB Polk
Cell Rep, 2020-10-20;33(3):108275.
Species: Mouse
Sample Types: Stool
-
Lipopolysaccharide O structure of adherent and invasive Escherichia coli regulates intestinal inflammation via complement C3
Authors: M Ohno, M Hasegawa, A Hayashi, G Caballero-, CJ Alteri, TD Lawley, N Kamada, G Núñez, N Inohara
PLoS Pathog, 2020-10-07;16(10):e1008928.
Species: Mouse
Sample Types: Feces
-
Dietary Emulsifiers Directly Impact Adherent-Invasive E.�coli Gene Expression to Drive Chronic Intestinal Inflammation
Authors: E Viennois, A Bretin, PE Dubé, AC Maue, CJG Dauriat, N Barnich, AT Gewirtz, B Chassaing
Cell Rep, 2020-10-06;33(1):108229.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Targeting the gut to prevent sepsis from a cutaneous burn
Authors: F Adiliaghda, P Cavallaro, V Mohad, M Almpani, F Kühn, MH Gharedaghi, M Najibi, LG Rahme, RA Hodin
JCI Insight, 2020-10-02;5(19):.
Species: Mouse
Sample Types: Feces
-
Dietary Fructose Alters the Composition, Localization and Metabolism of Gut Microbiota in Association with Worsening Colitis
Authors: DC Montrose, R Nishiguchi, S Basu, HA Staab, XK Zhou, H Wang, L Meng, M Johncilla, JR Cubillos-R, DK Morales, MT Wells, KW Simpson, S Zhang, B Dogan, C Jiao, Z Fei, A Oka, JW Herzog, RB Sartor, AJ Dannenberg
Cell Mol Gastroenterol Hepatol, 2020-09-20;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
In Vitro Characterization of Gut Microbiota-Derived Commensal Strains: Selection of Parabacteroides distasonis Strains Alleviating TNBS-Induced Colitis in Mice
Authors: B Cuffaro, ALW Assohoun, D Boutillier, L Súkeníková, J Desramaut, S Boudebbouz, S Salomé-Des, J Hrdý, AJ Waligora-D, E Maguin, C Grangette
Cells, 2020-09-16;9(9):.
Species: Mouse
Sample Types: Serum
-
Lipocalin-2 deficiency may predispose to the progression of spontaneous age-related adiposity in mice
Authors: K Meyers, M López, J Ho, S Wills, S Rayalam, S Taval
Sci Rep, 2020-09-03;10(1):14589.
Species: Mouse
Sample Types: Serum
-
Rhein modulates host purine metabolism in intestine through gut microbiota and ameliorates experimental colitis
Authors: J Wu, Z Wei, P Cheng, C Qian, F Xu, Y Yang, A Wang, W Chen, Z Sun, Y Lu
Theranostics, 2020-08-29;10(23):10665-10679.
Species: Mouse
Sample Types: Feces
-
Identification of novel loci controlling inflammatory bowel disease susceptibility utilizing the genetic diversity of wild-derived mice
Authors: KG Lahue, MK Lara, AA Linton, B Lavoie, Q Fang, MM McGill, JW Crothers, C Teuscher, GM Mawe, AL Tyler, JM Mahoney, DN Krementsov
Genes Immun., 2020-08-26;0(0):.
Species: Mouse
Sample Types: Fecal Homogenate, Feces
-
Neutrophil Extracellular Traps Impair Intestinal Barrier Function during Experimental Colitis
Authors: EY Lin, HJ Lai, YK Cheng, KQ Leong, LC Cheng, YC Chou, YC Peng, YH Hsu, HS Chiang
Biomedicines, 2020-08-05;8(8):.
Species: Mouse
Sample Types: Cell Lysates, Fecal Homogenates
-
Methyl-donor supplementation prevents intestinal colonization by Adherent-Invasive E. coli in a mouse model of Crohn's disease
Authors: E Gimier, M Chervy, A Agus, A Sivignon, E Billard, M Privat, S Viala, R Minet-Quin, A Buisson, E Vazeille, N Barnich, J Denizot
Sci Rep, 2020-07-31;10(1):12922.
Species: Mouse
Sample Types: Cell Culture Supernates, Tissue Homogenates
-
IFN-gamma promoted exosomes from mesenchymal stem cells to attenuate colitis via miR-125a and miR-125b
Authors: R Yang, H Huang, S Cui, Y Zhou, T Zhang, Y Zhou
Cell Death Dis, 2020-07-30;11(7):603.
Species: Mouse
Sample Types: Serum
-
Discovery of a Novel Multi-Strains Probiotic Formulation with Improved Efficacy toward Intestinal Inflammation
Authors: M Biagioli, A Carino, C Di Giorgio, S Marchianò, M Bordoni, R Roselli, E Distrutti, S Fiorucci
Nutrients, 2020-06-30;12(7):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Vitamin D Receptor Protects Against Dysbiosis and Tumorigenesis via the JAK/STAT Pathway in Intestine
Authors: YG Zhang, R Lu, S Wu, I Chatterjee, D Zhou, Y Xia, J Sun
Cell Mol Gastroenterol Hepatol, 2020-06-01;0(0):.
Species: Mouse
Sample Types: Fecal Homogenates
-
Post-Ischemic Renal Fibrosis Progression Is Halted by Delayed Contralateral Nephrectomy: The Involvement of Macrophage Activation
Authors: P Tod, EN Bukosza, B Róka, T Kaucsár, A Fintha, T Krenács, G Szénási, P Hamar
Int J Mol Sci, 2020-05-28;21(11):.
Species: Mouse
Sample Types: Plasma
-
Intestinal fungi are causally implicated in microbiome assembly and immune development in mice
Authors: E van Tilbur, VK Pettersen, MW Gutierrez, I Laforest-L, NG Jendzjowsk, JB Cavin, FA Vicentini, CM Keenan, HR Ramay, J Samara, WK MacNaughto, RJA Wilson, MM Kelly, KD McCoy, KA Sharkey, MC Arrieta
Nat Commun, 2020-05-22;11(1):2577.
Species: Mouse
Sample Types: Feces
-
Distinct iron homeostasis in C57BL/6 and Balb/c mouse strains
Authors: P Saha, X Xiao, Y Li, RM Golonka, AA Abokor, BS Yeoh, M Vijay-Kuma
Physiol Rep, 2020-05-01;8(9):e14441.
Species: Mouse
Sample Types: Serum
-
Gut Microbiota Modulate CD8�T Cell Responses to Influence Colitis-Associated Tumorigenesis
Authors: AI Yu, L Zhao, KA Eaton, S Ho, J Chen, S Poe, J Becker, A Gonzalez, D McKinstry, M Hasso, J Mendoza-Ca, J Whitfield, C Koumpouras, PD Schloss, EC Martens, GY Chen
Cell Rep, 2020-04-07;31(1):107471.
Species: Mouse
Sample Types: Stool Homogenate
-
Oral Administration of Heat-Treated Lactobacilli Modifies the Murine Microbiome and Reduces Citrobacter Induced Colitis
Authors: AK Warda, PH de Almeida, CM Hueston, G Di Benedet, AG Clooney, C Hill
Front Microbiol, 2020-01-30;11(0):69.
Species: Mouse
Sample Types: Feces
-
Increased intestinal permeability exacerbates sepsis through reduced hepatic SCD-1 activity and dysregulated iron recycling
Authors: M Kumar, A Leon Coria, S Cornick, B Petri, S Mayengbam, HB Jijon, F Moreau, J Shearer, K Chadee
Nat Commun, 2020-01-24;11(1):483.
Species: Mouse
Sample Types: Serum
-
Flagellin-elicited adaptive immunity suppresses flagellated microbiota and vaccinates against chronic inflammatory diseases
Authors: HQ Tran, RE Ley, AT Gewirtz, B Chassaing
Nat Commun, 2019-12-11;10(1):5650.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Chymase inhibition retards albuminuria in type 2 diabetes
Authors: BJ Bivona, S Takai, DM Seth, R Satou, LM Harrison-B
Physiol Rep, 2019-12-01;7(24):e14302.
Species: Mouse
Sample Types: Urine
-
Bacterial variability in the mammalian gut captured by a single-cell synthetic oscillator
Authors: DT Riglar, DL Richmond, L Potvin-Tro, AA Verdegaal, AD Naydich, S Bakshi, E Leoncini, LG Lyon, J Paulsson, PA Silver
Nat Commun, 2019-10-11;10(1):4665.
Species: Mouse
Sample Types: Feces
-
Std fimbriae-fucose interaction increases Salmonella-induced intestinal inflammation and prolongs colonization
Authors: A Suwandi, A Galeev, R Riedel, S Sharma, K Seeger, T Sterzenbac, L García Pas, EC Boyle, O Gal-Mor, M Hensel, J Casadesús, JF Baines, GA Grassl
PLoS Pathog., 2019-07-22;15(7):e1007915.
Species: Mouse
Sample Types: Tissue Culture Supernates
-
Secretomes from metastatic breast cancer cells, enriched for a prognostically unfavorable LCN2 axis, induce anti-inflammatory MSC actions and a tumor-supportive premetastatic lung
Authors: KJ Meade, F Sanchez, A Aguayo, N Nadales, SG Hamalian, TL Uhlendorf, LR Banner, JA Kelber
Oncotarget, 2019-04-30;10(32):3027-3039.
Species: Mouse
Sample Types: Plasma
-
Nlrp3 inflammasome activation and Gasdermin D-driven pyroptosis are immunopathogenic upon gastrointestinal norovirus infection
Authors: H Dubois, F Sorgeloos, ST Sarvestani, L Martens, Y Saeys, JM Mackenzie, M Lamkanfi, G van Loo, I Goodfellow, A Wullaert
PLoS Pathog., 2019-04-24;15(4):e1007709.
Species: Mouse
Sample Types: Feces
-
Innate lymphoid cells support regulatory T cells in the intestine through interleukin-2
Authors: L Zhou, C Chu, F Teng, NJ Bessman, J Goc, EK Santosa, GG Putzel, H Kabata, JR Kelsen, RN Baldassano, MA Shah, RE Sockolow, E Vivier, G Eberl, KA Smith, GF Sonnenberg
Nature, 2019-04-03;0(0):.
Species: Mouse
Sample Types: Feces
-
Intestinal Epithelial Cells and the Microbiome Undergo Swift Reprogramming at the Inception of Colonic Citrobacter rodentium Infection
Authors: EGD Hopkins, TI Roumelioti, C Mullineaux, JS Choudhary, G Frankel
MBio, 2019-04-02;10(2):.
Species: Mouse
Sample Types: Feces
-
Microbial Colonization Coordinates the Pathogenesis of a Klebsiella pneumoniae Infant Isolate
Authors: JL Pope, Y Yang, RC Newsome, W Sun, X Sun, M Ukhanova, J Neu, JP Issa, V Mai, C Jobin
Sci Rep, 2019-03-04;9(1):3380.
Species: Mouse
Sample Types: Feces
-
PAD4-dependent NETs generation are indispensable for intestinal clearance of Citrobacter rodentium
Authors: P Saha, BS Yeoh, X Xiao, RM Golonka, V Singh, Y Wang, M Vijay-Kuma
Mucosal Immunol, 2019-02-01;0(0):.
Species: Mouse
Sample Types: Serum
-
Disruption of Intestinal Homeostasis and Intestinal Microbiota During Experimental Autoimmune Uveitis
Authors: C Janowitz, YK Nakamura, C Metea, A Gligor, W Yu, L Karstens, JT Rosenbaum, M Asquith, P Lin
Invest. Ophthalmol. Vis. Sci., 2019-01-02;60(1):420-429.
Species: Mouse
Sample Types: Feces
-
The Citrobacter rodentium type III secretion system effector EspO affects mucosal damage repair and antimicrobial responses
Authors: CN Berger, VF Crepin, TI Roumelioti, JC Wright, N Serafini, M Pevsner-Fi, L Yu, E Elinav, JP Di Santo, JS Choudhary, G Frankel
PLoS Pathog., 2018-10-26;14(10):e1007406.
Species: Mouse
Sample Types: Feces
-
The Food Additive Maltodextrin Promotes Endoplasmic Reticulum Stress-Driven Mucus Depletion and Exacerbates Intestinal Inflammation
Authors: F Laudisi, D Di Fusco, V Dinallo, C Stolfi, A Di Grazia, I Marafini, A Colantoni, A Ortenzi, C Alteri, F Guerrieri, M Mavilio, F Ceccherini, M Federici, TT MacDonald, I Monteleone, G Monteleone
Cell Mol Gastroenterol Hepatol, 2018-09-11;7(2):457-473.
Species: Mouse
Sample Types: Feces
-
Myeloperoxidase deficiency attenuates systemic and dietary iron-induced adverse effects
Authors: X Xiao, P Saha, BS Yeoh, JA Hipp, V Singh, M Vijay-Kuma
J. Nutr. Biochem., 2018-08-21;62(0):28-34.
Species: Mouse
Sample Types: Tissue Homogenates
-
Genetic Ablation of Butyrate Utilization Attenuates Gastrointestinal Salmonella Disease
Authors: DN Bronner, F Faber, EE Olsan, MX Byndloss, NA Sayed, G Xu, W Yoo, D Kim, S Ryu, CB Lebrilla, AJ Bäumler
Cell Host Microbe, 2018-02-14;23(2):266-273.e4.
Species: Mouse
Sample Types: Feces
-
Respiratory Disease following Viral Lung Infection Alters the Murine Gut Microbiota
Authors: HT Groves, L Cuthbertso, P James, MF Moffatt, MJ Cox, JS Tregoning
Front Immunol, 2018-02-12;9(0):182.
Species: Mouse
Sample Types: Feces
-
Intergenerational transfer of antibiotic-perturbed microbiota enhances colitis in susceptible mice
Authors: AF Schulfer, T Battaglia, Y Alvarez, L Bijnens, VE Ruiz, M Ho, S Robinson, T Ward, LM Cox, AB Rogers, D Knights, RB Sartor, MJ Blaser
Nat Microbiol, 2017-11-27;0(0):.
Species: Mouse
Sample Types: Feces
-
RNA Nanotherapeutics for the Amelioration of Astroglial Reactivity
Authors: JA Smith, A Braga, J Verheyen, S Basilico, S Bandiera, C Alfaro-Cer, L Peruzzotti, D Shu, F Haque, P Guo, S Pluchino
Mol Ther Nucleic Acids, 2017-11-24;10(0):103-121.
Species: Mouse
Sample Types: Cell Culture Supernates
-
The ESRP1-GPR137 axis contributes to intestinal pathogenesis
Authors: LF Mager, VH Koelzer, R Stuber, L Thoo, I Keller, I Koeck, M Langenegge, C Simillion, SP Pfister, M Faderl, V Genitsch, I Tcymbarevi, P Juillerat, X Li, Y Xia, E Karamitopo, R Lyck, I Zlobec, S Hapfelmeie, R Bruggmann, KD McCoy, AJ Macpherson, C Müller, B Beutler, P Krebs
Elife, 2017-10-04;6(0):.
Species: Mouse
Sample Types: Feces
-
Isothiocyanate-enriched moringa seed extract alleviates ulcerative colitis symptoms in mice
Authors: Y Kim, AG Wu, A Jaja-Chime, BL Graf, C Waterman, MP Verzi, I Raskin
PLoS ONE, 2017-09-18;12(9):e0184709.
Species: Mouse
Sample Types: Feces
-
Microbiome-mediated neutrophil recruitment via CXCR2 and protection from amebic colitis
Authors: K Watanabe, CA Gilchrist, MJ Uddin, SL Burgess, MM Abhyankar, SN Moonah, Z Noor, JR Donowitz, BN Schneider, T Arju, E Ahmed, M Kabir, M Alam, R Haque, P Pramoonjag, B Mehrad, WA Petri
PLoS Pathog., 2017-08-17;13(8):e1006513.
Species: Mouse
Sample Types: Feces
-
Macrophage-derived IL-10 mediates mucosal repair by epithelial WISP-1 signaling
Authors: M Quiros, H Nishio, PA Neumann, D Siuda, JC Brazil, V Azcutia, R Hilgarth, MN O'Leary, V Garcia-Her, G Leoni, M Feng, G Bernal, H Williams, PH Dedhia, C Gerner-Smi, J Spence, CA Parkos, TL Denning, A Nusrat
J. Clin. Invest., 2017-08-07;0(0):.
Species: Mouse
Sample Types: Feces
-
Dietary Salt Exacerbates Experimental Colitis
Authors: AL Tubbs, B Liu, TD Rogers, RB Sartor, EA Miao
J. Immunol., 2017-06-21;0(0):.
Species: Mouse
Sample Types: Tissue Homogenates
-
Engineered bacteria can function in the mammalian gut long-term as live diagnostics of inflammation
Authors: DT Riglar, TW Giessen, M Baym, SJ Kerns, MJ Niederhube, RT Bronson, JW Kotula, GK Gerber, JC Way, PA Silver
Nat. Biotechnol., 2017-05-29;0(0):.
Species: Mouse
Sample Types: Tissue Homogenates
-
Chemical and pathogen-induced inflammation disrupt the murine intestinal microbiome
Authors: MA Borton, A Sabag-Daig, J Wu, LM Solden, BS O'Banion, RA Daly, RA Wolfe, JF Gonzalez, VH Wysocki, BMM Ahmer, KC Wrighton
Microbiome, 2017-04-27;5(1):47.
Species: Mouse
Sample Types: Feces
-
Bacterial Siderophores Hijack Neutrophil Functions
Authors: P Saha, BS Yeoh, RA Olvera, X Xiao, V Singh, D Awasthi, BC Subramania, Q Chen, M Dikshit, Y Wang, CA Parent, M Vijay-Kuma
J. Immunol., 2017-04-21;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Experimental atopic dermatitis depends on IL-33R signaling via MyD88 in dendritic cells
Authors: C Li, I Maillet, C Mackowiak, C Viala, F Di Padova, M Li, D Togbe, V Quesniaux, Y Lai, B Ryffel
Cell Death Dis, 2017-04-06;8(4):e2735.
Species: Mouse
Sample Types: Tissue Homogenates
-
Western diet induces colonic nitrergic myenteric neuropathy and dysmotility in mice via saturated fatty acid- and LPS-induced TLR4 signaling
Authors: François Reichardt
J. Physiol. (Lond.), 2017-02-08;0(0):.
Species: Mouse
Sample Types: Feces
-
Combination Therapy for Ulcerative Colitis: Orally Targeted Nanoparticles Prevent Mucosal Damage and Relieve Inflammation
Theranostics, 2016-09-25;6(12):2250-2266.
Species: Mouse
Sample Types: Feces
-
Microbiota-inducible Innate Immune, Siderophore Binding Protein Lipocalin 2 is Critical for Intestinal Homeostasis
Cell Mol Gastroenterol Hepatol, 2016-07-01;2(4):482-498.e6.
Species: Mouse
Sample Types: Complex Sample Type
-
Therapeutic Blockade of Immune Complex-Mediated Glomerulonephritis by Highly Selective Inhibition of Bruton's Tyrosine Kinase
Sci Rep, 2016-05-19;6(0):26164.
Species: Mouse
Sample Types: Serum
-
Pathogenic Upregulation of Glial Lipocalin-2 in the Parkinsonian Dopaminergic System
J Neurosci, 2016-05-18;36(20):5608-22.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Urine/Plasma Neutrophil Gelatinase Associated Lipocalin Ratio Is a Sensitive and Specific Marker of Subclinical Acute Kidney Injury in Mice.
Authors: Kaucsar T, Godo M, Revesz C, Kovacs M, Mocsai A, Kiss N, Albert M, Krenacs T, Szenasi G, Hamar P
PLoS ONE, 2016-01-29;11(1):e0148043.
Species: Mouse
Sample Types: Urine
-
The Effect of Cigarette Smoke Exposure on the Development of Inflammation in Lungs, Gut and Joints of TNFDeltaARE Mice.
Authors: Allais L, Kumar S, Debusschere K, Verschuere S, Maes T, De Smet R, Conickx G, De Vos M, Laukens D, Joos G, Brusselle G, Elewaut D, Cuvelier C, Bracke K
PLoS ONE, 2015-11-02;10(11):e0141570.
Species: Mouse
Sample Types: Feces
-
Low dietary iron intake restrains the intestinal inflammatory response and pathology of enteric infection by food-borne bacterial pathogens.
Authors: Kortman G, Mulder M, Richters T, Shanmugam N, Trebicka E, Boekhorst J, Timmerman H, Roelofs R, Wiegerinck E, Laarakkers C, Swinkels D, Bolhuis A, Cherayil B, Tjalsma H
Eur J Immunol, 2015-06-23;45(9):2553-67.
Species: Mouse
Sample Types: Feces
-
Dietary emulsifiers impact the mouse gut microbiota promoting colitis and metabolic syndrome.
Authors: Chassaing, Benoit, Koren, Omry, Goodrich, Julia K, Poole, Angela C, Srinivasan, Shanthi, Ley, Ruth E, Gewirtz, Andrew T
Nature, 2015-02-25;519(7541):92-6.
Species: Mouse
Sample Types: Feces
-
Annexin A1-containing extracellular vesicles and polymeric nanoparticles promote epithelial wound repair.
Authors: Leoni, Giovanna, Neumann, Philipp-, Kamaly, Nazila, Quiros, Miguel, Nishio, Hikaru, Jones, Hefin R, Sumagin, Ronen, Hilgarth, Roland S, Alam, Ashfaqul, Fredman, Gabriell, Argyris, Ioannis, Rijcken, Emile, Kusters, Dennis, Reutelingsperger, Chris, Perretti, Mauro, Parkos, Charles, Farokhzad, Omid C, Neish, Andrew S, Nusrat, Asma
J Clin Invest, 2015-02-09;125(3):1215-27.
Species: Mouse
Sample Types: Feces
-
Dendritic cell-secreted lipocalin2 induces CD8+ T-cell apoptosis, contributes to T-cell priming and leads to a TH1 phenotype.
Authors: Floderer M, Prchal-Murphy M, Vizzardelli C
PLoS ONE, 2014-07-10;9(7):e101881.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Allergic airway inflammation decreases lung bacterial burden following acute Klebsiella pneumoniae infection in a neutrophil- and CCL8-dependent manner.
Authors: Dulek D, Newcomb D, Goleniewska K, Cephus J, Zhou W, Reiss S, Toki S, Ye F, Zaynagetdinov R, Sherrill T, Blackwell T, Moore M, Boyd K, Kolls J, Peebles R
Infect Immun, 2014-06-23;82(9):3723-39.
Species: Mouse
Sample Types: Tissue Homogenates
-
Rapid renal alpha-1 antitrypsin gene induction in experimental and clinical acute kidney injury.
Authors: Zager R, Johnson A, Frostad K
PLoS ONE, 2014-05-21;9(5):e98380.
Species: Mouse
Sample Types: Urine
-
Differential role of lipocalin 2 during immune complex-mediated acute and chronic inflammation in mice.
Authors: Shashidharamurthy R, Machiah D, Aitken J, Putty K, Srinivasan G, Chassaing B, Parkos C, Selvaraj P, Vijay-Kumar M
Arthritis Rheum, 2013-04-01;65(4):1064-73.
Species: Mouse
Sample Types: Serum
-
Fecal lipocalin 2, a sensitive and broadly dynamic non-invasive biomarker for intestinal inflammation.
PLoS ONE, 2012-09-05;7(9):e44328.
Species: Mouse
Sample Types: Feces
-
Biomarkers of disease and treatment in murine and cynomolgus models of chronic asthma.
Authors: Louten J, Mattson JD, Malinao MC, Li Y, Emson C, Vega F, Wardle RL, Van Scott MR, Fick RB, McClanahan TK, de Waal Malefyt R, Beaumont M
Biomark Insights, 2012-07-10;7(0):87-104.
Species: Mouse
Sample Types: BALF
-
The receptor of advanced glycation end products plays a central role in advanced oxidation protein products-induced podocyte apoptosis.
Kidney Int, 2012-05-23;82(7):759-70.
Species: Mouse
Sample Types: Feces
-
Impaired resolution of inflammatory response in the lungs of JF1/Msf mice following carbon nanoparticle instillation.
Authors: Ganguly K, Upadhyay S, Irmler M, Takenaka S, Pukelsheim K, Beckers J, de Angelis MH, Hamelmann E, Stoeger T, Schulz H
Respir. Res., 2011-07-15;12(0):94.
Species: Mouse
Sample Types: BALF
-
Tumor microenvironment-derived proteins dominate the plasma proteome response during breast cancer induction and progression.
Authors: Pitteri SJ, Kelly-Spratt KS, Gurley KE
Cancer Res., 2011-06-08;71(15):5090-100.
Species: Mouse
Sample Types: Plasma
-
Plasma proteome profiles associated with inflammation, angiogenesis, and cancer.
Authors: Kelly-Spratt KS, Pitteri SJ, Gurley KE, Liggitt D, Chin A, Kennedy J, Wong CH, Zhang Q, Buson TB, Wang H, Hanash SM, Kemp CJ
PLoS ONE, 2011-05-12;6(5):e19721.
Species: Mouse
Sample Types: Plasma
-
Metabolic syndrome and altered gut microbiota in mice lacking Toll-like receptor 5.
Authors: Vijay-Kumar M, Aitken JD, Carvalho FA, Cullender TC, Mwangi S, Srinivasan S, Sitaraman SV, Knight R, Ley RE, Gewirtz AT
Science, 2010-03-04;328(5975):228-31.
Species: Mouse
Sample Types: Serum
-
Integrated proteomic analysis of human cancer cells and plasma from tumor bearing mice for ovarian cancer biomarker discovery.
Authors: Pitteri SJ, JeBailey L, Faca VM, Thorpe JD, Silva MA, Ireton RC, Horton MB, Wang H, Pruitt LC, Zhang Q, Cheng KH, Urban N, Hanash SM, Dinulescu DM
PLoS ONE, 2009-11-19;4(11):e7916.
Species: Mouse
Sample Types: Plasma
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