Mouse FAM3B Alexa Fluor® 405-conjugated Antibody

Catalog #: AF2867V Datasheet

Catalog #	Availability	Size / Price	Qty
AF2867V-100UG

All FAM3B Antibodies

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Mouse FAM3B Alexa Fluor® 405-conjugated Antibody Summary

Species Reactivity

Mouse

Specificity

Detects mouse FAM3B in direct ELISAs and Western blots. In direct ELISAs, approximately 35% cross‑reactivity with recombinant human FAM3B is observed, approximately 5% cross-reactivity with recombinant mouse (rm) FAM3C is observed, and

Source

Polyclonal Goat IgG

Purification

Antigen Affinity-purified

Immunogen

Mouse myeloma cell line NS0-derived recombinant mouse FAM3B
Glu30-Arg235
Accession # Q9D309

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 405 (Excitation= 405 nm, Emission= 421 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: FAM3B

FAM3B, also known as Pancreatic-Derived factor (PANDER), is a secreted, monomeric, 23 kDa glycoprotein that belongs to a new family of four-helix bundle cytokines. It is highly expressed in pancreatic islet cells and reproductive epithelium. FAM3B has been shown to induce b-cell apoptosis and decrease insulin secretion. Two alternative N-termini, at Glu 30 and Ser 46, have been observed for mature FAM3B. The long version of mature mouse FAM3B shares 80%, 92%, and 75% amino acid sequence homology with the human, rat and canine mature FAM3B, respectively.

Long Name

Family With Sequence Similarity 3, Member B

Entrez Gene IDs

54097 (Human)

Alternate Names

2-21; C21orf11; C21orf76PANDER; chromosome 21 open reading frame 11; Cytokine-like protein 2-21; D21M16SJHU19e; FAM3B; family with sequence similarity 3, member B; ORF9; pancreatic derived factor; Pancreatic-derived factor; PANDER; PRED44

Product Datasheets

Product Datasheet

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