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Mouse CXCL2/MIP-2 Quantikine ELISA Kit

Catalog #: MM200
176 Citations 2 Reviews Datasheet
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MM200
PMM200
SMM200
Mouse CXCL2/GRO beta/MIP-2/CINC-3 ELISA Standard Curve
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Citations (176)
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Summary Precision Recovery Linearity Data Examples Product Datasheets Preparation and Storage Background Related Research Areas

Mouse CXCL2/MIP-2 Quantikine ELISA Kit Summary

Assay Type
Solid Phase Sandwich ELISA
Format
96-well strip plate
Assay Length
4.5 hours
Sample Type & Volume Required Per Well
Cell Culture Supernates (50 uL), Serum (50 uL)
Sensitivity
1.5 pg/mL
Assay Range
7.8 - 500 pg/mL (Cell Culture Supernates, Serum)
Specificity
Natural and recombinant mouse MIP-2
Cross-reactivity
< 0.5% cross-reactivity observed with available related molecules.Cross-species reactivity not tested.
Interference
No significant interference observed with available related molecules.

Product Summary

The Quantikine Mouse MIP-2 Immunoassay is a 4.5 hour solid phase ELISA designed to measure mouse MIP-2 levels in cell culture supernates and serum. It contains E. coli-expressed recombinant mouse MIP-2 and antibodies raised against the recombinant factor. This immunoassay has been shown to quantitate the recombinant mouse MIP-2 accurately. Results obtained using natural mouse MIP-2 showed dose-response curves that were parallel to the standard curves obtained using the recombinant kit standards. These results indicate that this kit can be used to determine relative mass values for natural mouse MIP-2.

Precision

Intra-Assay Precision (Precision within an assay) Three samples of known concentration were tested on one plate to assess intra-assay precision
Inter-Assay Precision (Precision between assays) Three samples of known concentration were tested in separate assays to assess inter-assay precision

Cell Culture Supernates, Serum

Intra-Assay Precision Inter-Assay Precision
Sample 1 2 3 1 2 3
n 20 20 20 20 20 20
Mean (pg/mL) 17.7 53.9 363 16.9 52.1 346
Standard Deviation 0.5 1.3 7.3 1 2.3 15.4
CV% 2.8 2.4 2 5.9 4.4 4.5

Recovery

The recovery of mouse MIP-2 spiked to three levels throughout the range of the assay in various matrices was evaluated.

Sample Type Average % Recovery Range %
Cell Culture Supernates (n=10) 96 84-110
Serum (n=14) 100 94-116

Linearity

To assess the linearity of the assay, five or more samples containing and/or spiked with various concentrations of mouse MIP-2 in each matrix were diluted with Calibrator Diluent and then assayed.
Mouse CXCL2/GRO beta/MIP-2/CINC-3 ELISA Linearity

Scientific Data

N/A Mouse CXCL2/GRO beta/MIP-2/CINC-3 ELISA Standard Curve View Larger

Mouse CXCL2/GRO beta/MIP-2/CINC-3 ELISA Standard Curve

Product Datasheets

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Product Datasheet

Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: CXCL2/GRO beta/MIP-2/CINC-3

CXCL2/GRO beta, also called MIP-2 in mouse and CINC-3 in rat, is a member of the CXC chemokine family. Human CXCL2/GRO beta is 107 amino acids (aa) in length with a predicted molecular weight of 11 kDa. The mouse and rat orthologs share 70% and 71% aa sequence identity with the human protein, respectively. N-terminal aa 1-4 of CXCL2/GRO beta can be post-translationally cleaved which confers enhanced hematopoietic bioactivity. CXCL2/GRO beta is produced by a variety of cell types including monocytes and macrophages at sites of inflammation and is chemotactic for granulocytes, including neutrophils.

Entrez Gene IDs:
2920 (Human); 20310 (Mouse); 114105 (Rat)
Alternate Names:
chemokine (C-X-C motif) ligand 2; CINC-2a; CINC3; CINC-3; C-X-C Motif Chemokine 2; CXCL2; GRO beta; GRO2 oncogene; GRO2; GROB; Gro-beta; Growth-regulated protein beta; Macrophage inflammatory protein 2-alpha; melanoma growth stimulatory activity beta; MGSA beta; MGSA-b; MGSA-beta; MIP2; MIP-2; MIP2A; MIP-2a; MIP2-alpha; SCYB2
&#9888; WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Assay Procedure

Refer to the product for complete assay procedure.

Bring all reagents and samples to room temperature before use. It is recommended that all samples, standards, and controls be assayed in duplicate.
  1.   Prepare all reagents, standard dilutions, and samples as directed in the product insert.
  2.   Remove excess microplate strips from the plate frame, return them to the foil pouch containing the desiccant pack, and reseal.
    3. 50 µL Assay Diluent
  3.   Add 50 µL of Assay Diluent to each well.
    4. 50 µL Standard, Control, or Sample
  4.   Add 50 µL of Standard, Control, or sample to each well. Cover with a plate sealer, and incubate at room temperature for 2 hours.
  5.   Aspirate each well and wash, repeating the process 4 times for a total of 5 washes.
    6. 100 µL Conjugate
  6.   Add 100 µL of Conjugate to each well. Cover with a new plate sealer, and incubate at room temperature for 2 hours.
  7.   Aspirate and wash 5 times.
    8. 100 µL Substrate Solution
  8.   Add 100 µL Substrate Solution to each well. Incubate at room temperature for 30 minutes. PROTECT FROM LIGHT.
    9. 100 µL Stop Solution
  9.   Add 100 µL of Stop Solution to each well. Read at 450 nm within 30 minutes. Set wavelength correction to 540 nm or 570 nm.

Citations for Mouse CXCL2/MIP-2 Quantikine ELISA Kit

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

176 Citations: Showing 1 - 10
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  1. Spinal cord injury disrupts plasma extracellular vesicles cargoes leading to neuroinflammation in the brain and neurological dysfunction in aged male mice
    Authors: Lei, Z;Krishnamachary, B;Khan, NZ;Ji, Y;Li, Y;Li, H;Brunner, K;Faden, AI;Jones, JW;Wu, J;
    Brain, behavior, and immunity
    Species: Mouse
    Sample Types: Cell Culture Supernates
  2. Platelet-activating factor and protease-activated receptor 2 cooperate to promote neutrophil recruitment and lung inflammation through nuclear factor-kappa B transactivation
    Authors: Silva, IS;Almeida, AD;Lima Filho, ACM;Fernandes-Braga, W;Barra, A;Oliveira, HMC;Cassali, GD;Capettini, LSA;Menezes, GB;Alvarez-Leite, JI;Leite, MF;Klein, A;
    Scientific reports
    Species: Mouse
    Sample Types: BALF
  3. Ethanol Extracts from the Aerial Parts of Inula japonica and Potentilla chinensis Alleviate Airway Inflammation in Mice That Inhaled Particulate Matter 10 and Diesel Particulate Matter
    Authors: Jung, SH;Chung, KS;Na, CS;Ahn, HS;Shin, YK;Lee, KT;
    Nutrients
    Species: Mouse
    Sample Types: BALF
  4. Neutrophil metalloproteinase driven spleen damage hampers infection control of trypanosomiasis
    Authors: Pham, HTT;Magez, S;Choi, B;Baatar, B;Jung, J;Radwanska, M;
    Nature communications
    Species: Mouse
    Sample Types: Tissue Homogenates
  5. Naegleria fowleri Extracellular Vesicles Induce Proinflammatory Immune Responses in BV-2 Microglial Cells
    Authors: Lê, HG;Kang, JM;Võ, TC;Yoo, WG;Na, BK;
    International journal of molecular sciences
    Species: Mouse
    Sample Types: Cell Culture Supernates
  6. LHPP-mediated inorganic pyrophosphate hydrolysis-driven lysosomal acidification in astrocytes regulates adult neurogenesis
    Authors: Sha, L;Li, J;Shen, H;Wang, Q;Meng, P;Zhang, X;Deng, Y;Zhu, W;Xu, Q;
    Cell reports
    Species: Mouse
    Sample Types: Cell Culture Supernates
  7. The Scap-SREBP1-S1P/S2P lipogenesis signal orchestrates the homeostasis and spatiotemporal activation of NF-?B
    Authors: Fei, X;Huang, J;Li, F;Wang, Y;Shao, Z;Dong, L;Wu, Y;Li, B;Zhang, X;Lv, B;Zhao, Y;Weng, Q;Chen, K;Zhang, M;Yang, S;Zhang, C;Zhang, M;Li, W;Ying, S;Sun, Q;Chen, Z;Shen, H;
    Cell reports
    Species: Mouse
    Sample Types: BALF, Cell Culture Supernates
  8. Age-related changes in plasma extracellular vesicles influence neuroinflammation in the brain and neurological outcome after traumatic spinal cord injury
    Authors: Lei, Z;Krishnamachary, B;Ritzel, RM;Khan, NZ;Li, Y;Li, H;Brunner, K;Faden, AI;Wu, J;
    Research square
    Species: Mouse
    Sample Types: Cell Culture Supernates
  9. Mechanism and intervention of murine transfusion-related acute lung injury caused by anti-CD36 antibodies
    Authors: DW Chen, T Kang, XZ Xu, WJ Xia, X Ye, YB Wu, YR Xu, J Liu, H Ren, J Deng, YK Chen, HQ Ding, M Aslam, WM Zelek, BP Morgan, R Kapur, S Santoso, YS Fu
    JCI Insight, 2023-03-22;0(0):.
    Species: Mouse
    Sample Types: BALF
  10. METTL3-mediated m6A mRNA methylation regulates neutrophil activation through targeting TLR4 signaling
    Authors: S Luo, C Liao, L Zhang, C Ling, X Zhang, P Xie, G Su, Z Chen, L Zhang, T Lai, J Tang
    Cell Reports, 2023-03-14;42(3):112259.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  11. Glutamine prevents acute kidney injury by modulating oxidative stress and apoptosis in tubular epithelial cells
    Authors: K Thomas, L Zondler, N Ludwig, M Kardell, C Lüneburg, K Henke, S Mersmann, A Margraf, T Spieker, T Tekath, A Velic, R Holtmeier, J Hermann, V Jankowski, M Meersch, D Vestweber, M Westphal, J Roth, MA Schäfers, JA Kellum, CA Lowell, J Rossaint, A Zarbock
    JCI Insight, 2022-11-08;7(21):.
    Species: Mouse
    Sample Types: Urine
  12. Tubule-mitophagic secretion of SerpinG1 reprograms macrophages to instruct anti-septic acute kidney injury efficacy of high-dose ascorbate mediated by NRF2 transactivation
    Authors: Y Ni, GH Wu, JJ Cai, R Zhang, Y Zheng, JQ Liu, XH Yang, X Yang, Y Shen, JM Lai, XM Ye, SJ Mo
    International journal of biological sciences, 2022-08-08;18(13):5168-5184.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  13. Nanoparticles reduce monocytes within the lungs to improve outcomes after influenza virus infection in aged mice
    Authors: WJ Kelley, KM Wragg, J Chen, T Murthy, Q Xu, MT Boyne Ii, JR Podojil, A Elhofy, DR Goldstein
    JCI Insight, 2022-08-08;0(0):.
    Species: Mouse
    Sample Types: BALF
  14. Generation of antagonistic monoclonal antibodies against the neoepitope of active mouse interleukin (IL)-18 cleaved by inflammatory caspases
    Authors: Y Uchida, Y Nariai, E Obayashi, Y Tajima, T Koga, A Kawakami, T Urano, H Kamino
    Oncogene, 2022-06-13;727(0):109322.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  15. SGK1 negatively regulates inflammatory immune responses and protects against alveolar bone loss through modulation of TRAF3 activity
    Authors: X Han, J Ren, H Lohner, L Yakoumatos, R Liang, H Wang
    The Journal of Biological Chemistry, 2022-05-17;0(0):102036.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  16. Cytokines and Neurodegeneration in Epileptogenesis
    Authors: P Wolinski, D Ksiazek-Wi, A Glabinski
    Brain sciences, 2022-03-12;12(3):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  17. Intestinal microbe-dependent ?3 lipid metabolite alphaKetoA prevents inflammatory diseases in mice and cynomolgus macaques
    Authors: T Nagatake, S Kishino, E Urano, H Murakami, N Kitamura, K Konishi, H Ohno, P Tiwari, S Morimoto, E Node, J Adachi, Y Abe, J Isoyama, K Sawane, T Honda, A Inoue, A Uwamizu, T Matsuzaka, Y Miyamoto, SI Hirata, A Saika, Y Shibata, K Hosomi, A Matsunaga, H Shimano, M Arita, J Aoki, M Oka, A Matsutani, T Tomonaga, K Kabashima, M Miyachi, Y Yasutomi, J Ogawa, J Kunisawa
    Mucosal Immunology, 2022-01-10;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  18. Role of S100A8/A9 for Cytokine Secretion, Revealed in Neutrophils Derived from ER-Hoxb8 Progenitors
    Authors: Y Zhou, J Hann, V Schenten, S Plançon, JL Bueb, F Tolle, S Bréchard
    International Journal of Molecular Sciences, 2021-08-17;22(16):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  19. Pseudomonas aeruginosa-induced nociceptor activation increases susceptibility to infection
    Authors: T Lin, D Quellier, J Lamb, T Voisin, P Baral, F Bock, A Schönberg, R Mirchev, G Pier, I Chiu, M Gadjeva
    PloS Pathogens, 2021-05-06;17(5):e1009557.
    Species: Mouse
    Sample Types: Tissue Homogenates
  20. Phorbol 12-Myristate 13-Acetate Induced Toxicity Study and the Role of Tangeretin in Abrogating HIF-1&alpha-NF-&kappaB Crosstalk In Vitro and In Vivo
    Authors: SN Chang, DK Dey, ST Oh, WH Kong, KH Cho, EM Al-Olayan, BS Hwang, SC Kang, JG Park
    International Journal of Molecular Sciences, 2020-12-04;21(23):.
    Species: Mouse
    Sample Types: Tissue Culture Supernates
  21. The Gustatory Sensory G-Protein GNAT3 Suppresses Pancreatic Cancer Progression in Mice
    Authors: MT Hoffman, SB Kemp, DJ Salas-Esca, Y Zhang, NG Steele, S The, D Long, S Benitz, W Yan, RF Margolskee, F Bednar, M Pasca di M, HJ Wen, HC Crawford
    Cell Mol Gastroenterol Hepatol, 2020-08-31;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  22. Nintedanib Reduces Neutrophil Chemotaxis via Activating GRK2 in Bleomycin-Induced Pulmonary Fibrosis
    Authors: WC Chen, NJ Chen, HP Chen, WK Yu, VY Su, H Chen, HH Wu, KY Yang
    Int J Mol Sci, 2020-07-02;21(13):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  23. ASK1 promotes uterine inflammation leading to pathological preterm birth
    Authors: M Yoshikawa, T Iriyama, K Suzuki, S Sayama, T Tsuruga, K Kumasawa, T Nagamatsu, K Homma, I Naguro, Y Osuga, H Ichijo, T Fujii
    Sci Rep, 2020-02-05;10(1):1887.
    Species: Mouse
    Sample Types: Peritoneal Fluid
  24. Cysteine-Capped Hydrogels Incorporating Copper as Effective Antimicrobial Materials against Methicillin-Resistant Staphylococcus aureus
    Authors: JJ Yang, YC Huang, TH Chuang, DR Herr, MF Hsieh, CJ Huang, CM Huang
    Microorganisms, 2020-01-21;8(2):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  25. Lack of whey acidic protein four disulphide core (WFDC) 2 protease inhibitor causes neonatal death from respiratory failure in mice
    Authors: K Nakajima, M Ono, U Radovi?, S Dizdarevi?, SI Tomizawa, K Kuroha, G Naganatsu, I Hoshi, R Matsunaga, T Shirakawa, T Kurosawa, Y Miyazaki, M Seki, Y Suzuki, H Koseki, M Nakamura, T Suda, K Ohbo
    Dis Model Mech, 2019-11-12;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  26. Adoptive transfer of type 1 regulatory T cells suppressed the development of airway hyperresponsiveness in ovalbumin-induced airway inflammation model mice
    Authors: M Matsuda, K Doi, T Tsutsumi, M Inaba, J Hamaguchi, T Terada, R Kawata, K Kitatani, T Nabe
    J. Pharmacol. Sci., 2019-11-02;141(4):139-145.
    Species: Mouse
    Sample Types: BALF
  27. Isoflavone Aglycones Attenuate Cigarette Smoke-Induced Emphysema via Suppression of Neutrophilic Inflammation in a COPD Murine Model
    Authors: K Kojima, K Asai, H Kubo, A Sugitani, Y Kyomoto, A Okamoto, K Yamada, N Ijiri, T Watanabe, K Hirata, T Kawaguchi
    Nutrients, 2019-08-29;11(9):.
    Species: Mouse
    Sample Types: BALF
  28. Inactivation of MTOR promotes autophagy-mediated epithelial injury in particulate matter-induced airway inflammation
    Authors: YF Wu, ZY Li, LL Dong, WJ Li, YP Wu, J Wang, HP Chen, HW Liu, M Li, CL Jin, HQ Huang, SM Ying, W Li, HH Shen, ZH Chen
    Autophagy, 2019-06-16;0(0):1-16.
    Species: Mouse
    Sample Types: BALF
  29. Tofacitinib enhances delivery of antibody-based therapeutics to tumor cells through modulation of inflammatory cells
    Authors: N Simon, A Antignani, SM Hewitt, M Gadina, C Alewine, D FitzGerald
    JCI Insight, 2019-03-07;0(0):.
    Species: Mouse
    Sample Types: Serum
  30. Ovalbumin-sensitized mice have altered airway inflammation to agriculture organic dust
    Authors: KJ Warren, JD Dickinson, AJ Nelson, TA Wyatt, DJ Romberger, JA Poole
    Respir. Res., 2019-03-07;20(1):51.
    Species: Mouse
    Sample Types: BALF
  31. Induced Pluripotent Stem Cells Regulate TREM-1 Expression and the p38 MAPK Pathway in Endotoxin-Induced Acute Lung Injury
    Authors: VY Su, KY Yang, SH Chiou, NJ Chen, MH Mo, CS Lin, CT Wang
    Stem Cells, 2019-02-16;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  32. 1-Palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol (PLAG) attenuates gemcitabine-induced neutrophil extravasation
    Authors: J Jeong, YJ Kim, DY Lee, BG Moon, KY Sohn, SY Yoon, JW Kim
    Cell Biosci, 2019-01-03;9(0):4.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  33. Endothelial cell-specific anticoagulation reduces inflammation in a mouse model of acute lung injury
    Authors: J Lou, Y Hu, MD Wu, LQ Che, YF Wu, Y Zhao, BP Tian, ZQ Bao, C Zhu, YP Wu, LL He, CX Bai, J Zhou, SM Ying, W Li, ZH Chen, DX Chen, A Dorling, HH Shen
    Acta Pharmacol. Sin., 2018-11-16;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  34. Snail promotes ovarian cancer progression by recruiting myeloid-derived suppressor cells via CXCR2 ligand upregulation
    Authors: M Taki, K Abiko, T Baba, J Hamanishi, K Yamaguchi, R Murakami, K Yamanoi, N Horikawa, Y Hosoe, E Nakamura, A Sugiyama, M Mandai, I Konishi, N Matsumura
    Nat Commun, 2018-04-27;9(1):1685.
    Species: Mouse
    Sample Types: Serum
  35. TIM?4 blockade of KCs combined with exogenous TGF?β injection helps to reverse acute rejection and prolong the survival rate of mice receiving liver allografts
    Authors: H Wu, X Xu, J Li, J Gong, M Li
    Int. J. Mol. Med., 2018-03-30;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  36. MTOR Suppresses Environmental Particle-Induced Inflammatory Response in Macrophages
    Authors: Z Li, Y Wu, H Chen, C Zhu, L Dong, Y Wang, H Liu, X Xu, J Zhou, Y Wu, W Li, S Ying, H Shen, Z Chen
    J. Immunol., 2018-03-21;0(0):.
    Species: Mouse
    Sample Types: BALF
  37. Age-related decline of the acute local inflammation response: a mitigating role for the adenosine A2A receptor
    Authors: C Laflamme, GB Mailhot, M Pouliot
    Aging (Albany NY), 2017-10-18;9(10):2083-2097.
    Species: Mouse
    Sample Types: Air Pouch Exudate
  38. Two novel roles of buffalo milk lactoperoxidase, antibiofilm agent and immunomodulator against multidrug resistant Salmonella enterica serovar Typhi and Listeria monocytogenes
    Authors: L Mahdi, H Musafer, L Zwain, I Salman, I Al-Joofy, K Rasool, A Mussa, S Al-Kakei, R Al-Oqaili, S Al-Alak, A Chaloob, A Abdulkaree, B Hussein, N Mahdi, N Taher
    Microb. Pathog., 2017-06-03;0(0):.
    Species: Mouse
    Sample Types: Serum
  39. Antiinflammatory actions of inorganic nitrate stabilize the atherosclerotic plaque
    Authors: RS Khambata, SM Ghosh, KS Rathod, T Thevathasa, F Filomena, Q Xiao, A Ahluwalia
    Proc. Natl. Acad. Sci. U.S.A, 2017-01-05;0(0):.
    Species: Mouse
    Sample Types: Plasma
  40. Systemic IL-6 Effector Response in Mediating Systemic Bone Loss Following Inhalation of Organic Dust
    Authors: Jill A Poole
    J. Interferon Cytokine Res., 2016-11-22;0(0):.
    Species: Mouse
    Sample Types: BALF
  41. Targeting thrombomodulin to circulating red blood cells augments its protective effects in models of endotoxemia and ischemia-reperfusion injury
    Authors: Vladimir R Muzykantov
    FASEB J., 2016-11-11;0(0):.
    Species: Mouse
    Sample Types: Plasma
  42. Plasminogen activator inhibitor-1 does not contribute to the pulmonary pathology induced by acute exposure to ozone
    Physiol Rep, 2016-09-01;4(18):.
    Species: Mouse
    Sample Types: BALF
  43. CF Lung Infection and Inflammation: IL-17 Pathophysiology and Therapeutic Intervention
    Authors: Daniel Hsu
    Infect Immun, 2016-08-19;0(0):.
    Species: Mouse
    Sample Types: BALF
  44. Toll-Like Receptor 4 Signaling Pathway Mediates Inhalant Organic Dust-Induced Bone Loss
    PLoS ONE, 2016-08-01;11(8):e0158735.
    Species: Mouse
    Sample Types: BALF
  45. Toll-like Receptor 4 Agonistic Antibody Promotes Host Defense against Chronic Pseudomonas aeruginosa Lung Infection in Mice
    Authors: S Nakamura, N Iwanaga, M Seki, K Fukudome, K Oshima, T Miyazaki, K Izumikawa, K Yanagihara, Y Miyazaki, H Mukae, S Kohno
    Infect Immun, 2016-06-23;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  46. CD11c.DTR mice develop a fatal fulminant myocarditis after local or systemic treatment with diphtheria toxin
    Eur J Immunol, 2016-06-08;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  47. DUOX-Mediated Signaling Is Not Required for LPS-Induced Neutrophilic Response in the Airways.
    Authors: Chang S, Linderholm A, Harper R
    PLoS ONE, 2015-07-06;10(7):e0131810.
    Species: Mouse
    Sample Types: BALF
  48. Conditioned media from adipose stromal cells limit lipopolysaccharide-induced lung injury, endothelial hyperpermeability and apoptosis.
    Authors: Lu H, Poirier C, Cook T, Traktuev D, Merfeld-Clauss S, Lease B, Petrache I, March K, Bogatcheva N
    J Transl Med, 2015-02-21;13(0):67.
    Species: Mouse
    Sample Types: BALF
  49. Blau syndrome-associated Nod2 mutation alters expression of full-length NOD2 and limits responses to muramyl dipeptide in knock-in mice.
    Authors: Dugan J, Griffiths E, Snow P, Rosenzweig H, Lee E, Brown B, Carr D, Rose C, Rosenbaum J, Davey M
    J Immunol, 2014-11-26;194(1):349-57.
    Species: Mouse
    Sample Types: Serum
  50. Nuclear factor of activated T cells regulates neutrophil recruitment, systemic inflammation, and T-cell dysfunction in abdominal sepsis.
    Authors: Zhang S, Luo L, Wang Y, Gomez M, Thorlacius H
    Infect Immun, 2014-05-27;82(8):3275-88.
    Species: Mouse
    Sample Types: Tissue Homogenates
  51. Recombinant human hyaluronidase PH20 does not stimulate an acute inflammatory response and inhibits lipopolysaccharide-induced neutrophil recruitment in the air pouch model of inflammation.
    Authors: Huang Z, Zhao C, Chen Y, Cowell J, Wei G, Kultti A, Huang L, Thompson C, Rosengren S, Frost G, Shepard H
    J Immunol, 2014-04-28;192(11):5285-95.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  52. Fibrates ameliorate the course of bacterial sepsis by promoting neutrophil recruitment via CXCR2.
    Authors: Tancevski I, Nairz M, Duwensee K, Auer K, Schroll A, Heim C, Feistritzer C, Hoefer J, Gerner R, Moschen A, Heller I, Pallweber P, Li X, Theurl M, Demetz E, Wolf A, Wolf D, Eller P, Ritsch A, Weiss G
    EMBO Mol Med, 2014-04-06;6(6):810-20.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  53. Peripheral blood monocyte-derived chemokine blockade prevents murine transfusion-related acute lung injury (TRALI).
    Authors: McKenzie C, Kim M, Singh T, Milev Y, Freedman J, Semple J
    Blood, 2014-03-17;123(22):3496-503.
    Species: Mouse
    Sample Types: Serum
  54. Blockade of Fas signaling in breast cancer cells suppresses tumor growth and metastasis via disruption of Fas signaling-initiated cancer-related inflammation.
    Authors: Liu Q, Tan Q, Zheng Y, Chen K, Qian C, Li N, Wang Q, Cao X
    J Biol Chem, 2014-03-13;289(16):11522-35.
    Species: Mouse
    Sample Types: Whole Cells
  55. Pseudomonas aeruginosa MucD protease mediates keratitis by inhibiting neutrophil recruitment and promoting bacterial survival.
    Authors: Mochizuki Y, Suzuki T, Oka N, Zhang Y, Hayashi Y, Hayashi N, Gotoh N, Ohashi Y
    Invest Ophthalmol Vis Sci, 2014-01-09;55(1):240-6.
    Species: Mouse
    Sample Types: Tissue Homogenates
  56. Vascular immunotargeting to endothelial determinant ICAM-1 enables optimal partnering of recombinant scFv-thrombomodulin fusion with endogenous cofactor.
    Authors: Greineder, Colin F, Chacko, Ann-Mari, Zaytsev, Sergei, Zern, Blaine J, Carnemolla, Ronald, Hood, Elizabet, Han, Jingyan, Ding, Bi-Sen, Esmon, Charles, Muzykantov, Vladimir
    PLoS ONE, 2013-11-14;8(11):e80110.
    Species: Mouse
    Sample Types: Lavage Fluid
  57. CXCR2-mediated tumor-associated neutrophil recruitment is regulated by IFN-beta.
    Authors: Jablonska J, Wu C, Andzinski L, Leschner S, Weiss S
    Int J Cancer, 2013-10-31;134(6):1346-58.
    Species: Mouse
    Sample Types: Tissue Homogenates
  58. A novel C5a-neutralizing mirror-image (l-)aptamer prevents organ failure and improves survival in experimental sepsis.
    Authors: Hoehlig, Kai, Maasch, Christia, Shushakova, Nelli, Buchner, Klaus, Huber-Lang, Markus, Purschke, Werner G, Vater, Axel, Klussmann, Sven
    Mol Ther, 2013-07-26;21(12):2236-46.
    Species: Mouse
    Sample Types: Peritoneal Lavage Fluid
  59. Inhibition of geranylgeranyltransferase attenuates neutrophil accumulation and tissue injury in severe acute pancreatitis.
    Authors: Merza M, Wetterholm E, Zhang S, Regner S, Thorlacius H
    J Leukoc Biol, 2013-06-06;94(3):493-502.
    Species: Mouse
    Sample Types: Tissue Homogenates
  60. Characterization of a distinct host response profile to Pneumocystis murina asci during clearance of pneumocystis pneumonia.
    Authors: Linke M, Ashbaugh A, Collins M, Lynch K, Cushion M
    Infect Immun, 2013-01-14;81(3):984-95.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  61. Endothelial cell peroxisome proliferator-activated receptor gamma reduces endotoxemic pulmonary inflammation and injury.
    Authors: Reddy A, Lakshmi S, Kleinhenz J, Sutliff R, Hart C, Reddy R
    J Immunol, 2012-10-26;189(11):5411-20.
    Species: Mouse
    Sample Types: BALF
  62. Human mesenchymal stem/stromal cells cultured as spheroids are self-activated to produce prostaglandin E2 that directs stimulated macrophages into an anti-inflammatory phenotype.
    Authors: Ylostalo J, Bartosh T, Coble K, Prockop D
    Stem Cells, 2012-10-01;30(10):2283-96.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  63. CRTH2 Is A Critical Regulator of Neutrophil Migration and Resistance to Polymicrobial Sepsis.
    Authors: Ishii M, Asano K, Namkoong H, Tasaka S, Mizoguchi K, Asami T, Kamata H, Kimizuka Y, Fujiwara H, Funatsu Y, Kagawa S, Miyata J, Ishii K, Nakamura M, Hirai H, Nagata K, Kunkel SL, Hasegawa N, Betsuyaku T
    J. Immunol., 2012-04-27;188(11):5655-64.
    Species: Mouse
    Sample Types: Peritoneal Lavage Fluid
  64. Inhibiting Mer receptor tyrosine kinase suppresses STAT1, SOCS1/3, and NF-kappaB activation and enhances inflammatory responses in lipopolysaccharide-induced acute lung injury.
    J. Cell. Sci., 2012-03-16;91(6):921-32.
    Species: Mouse
    Sample Types: BALF
  65. Modelling of mouse experimental colitis by global property screens: a holistic approach to assess drug effects in inflammatory bowel disease.
    Authors: Gottfries J, Melgar S, Michaelsson E
    PLoS ONE, 2012-01-18;7(1):e30005.
    Species: Mouse
    Sample Types: Tissue Homogenates
  66. Neutrophil-derived matrix metalloproteinase-9 is a potent activator of trypsinogen in acinar cells in acute pancreatitis.
    Authors: Awla D, Abdulla A, Syk I, Jeppsson B, Regner S, Thorlacius H
    J. Leukoc. Biol., 2011-11-18;91(5):711-9.
    Species: Mouse
    Sample Types: Serum
  67. Suppression of cytokine storm with a sphingosine analog provides protection against pathogenic influenza virus.
    Authors: Walsh KB, Teijaro JR, Wilker PR
    Proc. Natl. Acad. Sci. U.S.A., 2011-06-29;108(29):12018-23.
    Species: Mouse
    Sample Types: BALF
  68. Involvement of adenosine A2A receptors in engulfment-dependent apoptotic cell suppression of inflammation.
    Authors: Koroskenyi K, Duro E, Pallai A, Sarang Z, Kloor D, Ucker DS, Beceiro S, Castrillo A, Chawla A, Ledent CA, Fésüs L, Szondy Z
    J. Immunol., 2011-05-18;186(12):7144-55.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  69. TNF-alpha promotes LPA1- and LPA3-mediated recruitment of leukocytes in vivo through CXCR2 ligand chemokines.
    Authors: Zhao C, Sardella A, Chun J, Poubelle PE, Fernandes MJ, Bourgoin SG
    J. Lipid Res., 2011-04-26;52(7):1307-18.
    Species: Mouse
    Sample Types: Air Pouch Exudate
  70. CXCL1 and its receptor, CXCR2, mediate murine sickle cell vaso-occlusion during hemolytic transfusion reactions.
    Authors: Jang JE, Hod EA, Spitalnik SL
    J. Clin. Invest., 2011-03-07;121(4):1397-401.
    Species: Mouse
    Sample Types: Plasma
  71. Overexpression of sICAM-1 in the Alveolar Epithelial Space Results in an Exaggerated Inflammatory Response and Early Death in Gram Negative Pneumonia.
    Authors: Mendez MP, Monroy YK, Du M
    Respir. Res., 2011-01-19;12(1):12.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  72. TLR4 through IFN-beta promotes low molecular mass hyaluronan-induced neutrophil apoptosis.
    Authors: Leu SW, Shi L, Xu C, Zhao Y, Liu B, Li Y, Shiedlin A, Xiang C, Shen H, Quinn DA, Hales CA, Zhao H
    J. Immunol., 2010-11-22;186(1):556-62.
    Species: Mouse
    Sample Types: BALF
  73. Priming with endotoxin increases acute lung injury in mice by enhancing the severity of lung endothelial injury.
    Authors: Lee JS, Su X, Rackley C, Matthay MA, Gupta N
    Anat Rec (Hoboken), 2010-11-16;294(1):165-72.
    Species: Mouse
    Sample Types: BALF
  74. S100A8/A9 is not involved in host defense against murine urinary tract infection.
    Authors: Dessing MC, Butter LM, Teske GJ
    PLoS ONE, 2010-10-14;5(10):e13394.
    Species: Mouse
    Sample Types: Tissue Homogenates
  75. Ability of IDO to attenuate liver injury in alpha-galactosylceramide-induced hepatitis model.
    Authors: Ito H, Hoshi M, Ohtaki H, Taguchi A, Ando K, Ishikawa T, Osawa Y, Hara A, Moriwaki H, Saito K, Seishima M
    J. Immunol., 2010-09-15;185(8):4554-60.
    Species: Mouse
    Sample Types: Serum
  76. Uropathogenic Escherichia coli modulates immune responses and its curli fimbriae interact with the antimicrobial peptide LL-37.
    Authors: Kai-Larsen Y, Luthje P, Chromek M, Peters V, Wang X, Holm A, Kadas L, Hedlund KO, Johansson J, Chapman MR, Jacobson SH, Romling U, Agerberth B, Brauner A
    PLoS Pathog., 2010-07-22;6(0):e1001010.
    Species: Mouse
    Sample Types: Urine
  77. Recipient T lymphocytes modulate the severity of antibody-mediated transfusion-related acute lung injury.
    Authors: Fung YL, Kim M, Tabuchi A
    Blood, 2010-07-08;116(16):3073-9.
    Species: Mouse
    Sample Types: Serum
  78. P2X7 receptor activation induces CXCL2 production in microglia through NFAT and PKC/MAPK pathways.
    Authors: Shiratori M, Tozaki-Saitoh H, Yoshitake M
    J. Neurochem., 2010-05-13;114(3):810-9.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  79. NOD1 contributes to mouse host defense against Helicobacter pylori via induction of type I IFN and activation of the ISGF3 signaling pathway.
    Authors: Watanabe T, Asano N, Fichtner-Feigl S, Gorelick PL, Tsuji Y, Matsumoto Y, Chiba T, Fuss IJ, Kitani A, Strober W
    J. Clin. Invest., 2010-04-12;120(5):1645-62.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  80. TLR4 is a negative regulator in noninfectious lung inflammation.
    Authors: Zhao H, Leu SW, Shi L, Dedaj R, Zhao G, Garg HG, Shen L, Lien E, Fitzgerald KA, Shiedlin A, Shen H, Quinn DA, Hales CA
    J. Immunol., 2010-03-31;184(9):5308-14.
    Species: Mouse
    Sample Types: BALF
  81. Varying susceptibility of pulmonary cytokine production to lipopolysaccharide in mice.
    Authors: Alm AS, Li K, Yang D, Andersson R, Lu Y, Wang X
    Cytokine, 2009-12-29;49(3):256-63.
    Species: Mouse
    Sample Types: BALF
  82. Absence or inhibition of matrix metalloproteinase-8 decreases ventilator-induced lung injury.
    Authors: Albaiceta GM, Gutierrez-Fernandez A, Garcia-Prieto E, Puente XS, Parra D, Astudillo A, Campestre C, Cabrera S, Gonzalez-Lopez A, Fueyo A, Taboada F, Lopez-Otin C
    Am. J. Respir. Cell Mol. Biol., 2009-12-07;43(5):555-63.
    Species: Mouse
    Sample Types: Tissue Homogenates
  83. Both FcgammaRIV and FcgammaRIII are essential receptors mediating type II and type III autoimmune responses via FcRgamma-LAT-dependent generation of C5a.
    Authors: Syed SN, Konrad S, Wiege K, Nieswandt B, Nimmerjahn F, Schmidt RE, Gessner JE
    Eur. J. Immunol., 2009-12-01;39(12):3343-56.
    Species: Mouse
    Sample Types: BALF
  84. Epithelial overexpression of SOCS-3 in transgenic mice exacerbates wound inflammation in the presence of elevated TGF-beta1.
    Authors: Linke A, Goren I, Bosl MR, Pfeilschifter J, Frank S
    J. Invest. Dermatol., 2009-11-19;130(3):866-75.
    Species: Mouse
    Sample Types: Tissue Homogenates
  85. Early protection from burn-induced acute lung injury by deletion of preprotachykinin-A gene.
    Authors: Sio SW, Moochhala S, Lu J
    Am. J. Respir. Crit. Care Med., 2009-10-01;181(1):36-46.
    Species: Mouse
    Sample Types: Tissue Homogenates
  86. Bbeta(15-42) protects against acid-induced acute lung injury and secondary pseudomonas pneumonia in vivo.
    Authors: Matt U, Warszawska JM, Bauer M, Dietl W, Mesteri I, Doninger B, Haslinger I, Schabbauer G, Perkmann T, Binder CJ, Reingruber S, Petzelbauer P, Knapp S
    Am. J. Respir. Crit. Care Med., 2009-09-17;180(12):1208-17.
    Species: Mouse
    Sample Types: BALF
  87. Enhanced production of IL-17A during zymosan-induced peritonitis in obese mice.
    Authors: Pini M, Fantuzzi G
    J. Leukoc. Biol., 2009-09-10;87(1):51-8.
    Species: Mouse
    Sample Types: Peritoneal Lavage Fluid
  88. Syndecan-1 shedding facilitates the resolution of neutrophilic inflammation by removing sequestered CXC chemokines.
    Authors: Hayashida K, Parks WC, Park PW
    Blood, 2009-07-28;114(14):3033-43.
    Species: Mouse
    Sample Types: Serum
  89. TLR9 activation coupled to IL-10 deficiency induces adverse pregnancy outcomes.
    Authors: Thaxton JE, Romero R, Sharma S
    J. Immunol., 2009-06-26;183(2):1144-54.
    Species: Mouse
    Sample Types: Serum
  90. IL-17 receptor signaling is required to control polymicrobial sepsis.
    Authors: Freitas A, Alves-Filho JC, Victoni T, Secher T, Lemos HP, Sonego F, Cunha FQ, Ryffel B
    J. Immunol., 2009-06-15;182(12):7846-54.
    Species: Mouse
    Sample Types: Tissue Secretion
  91. T cells dampen innate immune responses through inhibition of NLRP1 and NLRP3 inflammasomes.
    Authors: Guarda G, Dostert C, Staehli F, Cabalzar K, Castillo R, Tardivel A, Schneider P, Tschopp J
    Nature, 2009-06-03;460(7252):269-73.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  92. C/EBPalpha is required for pulmonary cytoprotection during hyperoxia.
    Authors: Xu Y, Saegusa C, Schehr A, Grant S, Whitsett JA, Ikegami M
    Am. J. Physiol. Lung Cell Mol. Physiol., 2009-05-22;297(2):L286-98.
    Species: Mouse
    Sample Types: Tissue Homogenates
  93. The E-selectin ligand basigin/CD147 is responsible for neutrophil recruitment in renal ischemia/reperfusion.
    Authors: Kato N, Yuzawa Y, Kosugi T
    J. Am. Soc. Nephrol., 2009-05-14;20(7):1565-76.
    Species: Mouse
    Sample Types: Tissue Homogenates
  94. Anchoring fusion thrombomodulin to the endothelial lumen protects against injury-induced lung thrombosis and inflammation.
    Authors: Ding BS, Hong N, Christofidou-Solomidou M, Gottstein C, Albelda SM, Cines DB, Fisher AB, Muzykantov VR
    Am. J. Respir. Crit. Care Med., 2009-04-02;180(3):247-56.
    Species: Mouse
    Sample Types: BALF
  95. Acute lung injury is reduced in fat-1 mice endogenously synthesizing n-3 fatty acids.
    Authors: Mayer K, Kiessling A, Ott J, Schaefer MB, Hecker M, Henneke I, Schulz R, Gunther A, Wang J, Wu L, Roth J, Seeger W, Kang JX
    Am. J. Respir. Crit. Care Med., 2009-01-08;179(6):474-83.
    Species: Mouse
    Sample Types: BALF
  96. A small molecule CRTH2 antagonist inhibits FITC-induced allergic cutaneous inflammation.
    Authors: Boehme SA, Franz-Bacon K, Chen EP, Sasik R, Sprague LJ, Ly TW, Hardiman G, Bacon KB
    Int. Immunol., 2008-12-09;21(1):81-93.
    Species: Mouse
    Sample Types: Tissue Homogenates
  97. Plasminogen activator inhibitor-1 regulates neutrophil influx during acute pyelonephritis.
    Authors: Roelofs JJ, Teske GJ, Bonta PI, de Vries CJ, Meijers JC, Weening JJ, van der Poll T, Florquin S
    Kidney Int., 2008-09-17;75(1):52-9.
    Species: Mouse
    Sample Types: Tissue Homogenates
  98. Endogenous hydrogen sulfide regulates inflammatory response by activating the ERK pathway in polymicrobial sepsis.
    Authors: Zhang H, Moochhala SM, Bhatia M
    J. Immunol., 2008-09-15;181(6):4320-31.
    Species: Mouse
    Sample Types: Tissue Homogenates
  99. TLR-2 and IL-17A in chitin-induced macrophage activation and acute inflammation.
    Authors: Da Silva CA, Hartl D, Liu W, Lee CG, Elias JA
    J. Immunol., 2008-09-15;181(6):4279-86.
    Species: Mouse
    Sample Types: BALF
  100. Particulate matter in cigarette smoke alters iron homeostasis to produce a biological effect.
    Authors: Ghio AJ, Hilborn ED, Stonehuerner JG, Dailey LA, Carter JD, Richards JH, Crissman KM, Foronjy RF, Uyeminami DL, Pinkerton KE
    Am. J. Respir. Crit. Care Med., 2008-08-21;178(11):1130-8.
    Species: Rat
    Sample Types: BALF
  101. The nuclear factor kappa-B pathway in airway epithelium regulates neutrophil recruitment and host defence following Pseudomonas aeruginosa infection.
    Authors: Chen SM, Cheng DS, Williams BJ, Sherrill TP, Han W, Chont M, Saint-Jean L, Christman JW, Sadikot RT, Yull FE, Blackwell TS
    Clin. Exp. Immunol., 2008-07-18;0(0):.
    Species: Mouse
    Sample Types: BALF
  102. Myeloid Src kinases regulate phagocytosis and oxidative burst in pneumococcal meningitis by activating NADPH oxidase.
    Authors: Paul R, Obermaier B, Van Ziffle J, Angele B, Pfister HW, Lowell CA, Koedel U
    J. Leukoc. Biol., 2008-07-14;84(4):1141-50.
    Species: Mouse
    Sample Types: Tissue Homogenates
  103. The neuropeptide substance P is a critical mediator of burn-induced acute lung injury.
    Authors: Sio SW, Puthia MK, Lu J, Moochhala S, Bhatia M
    J. Immunol., 2008-06-15;180(12):8333-41.
    Species: Mouse
    Sample Types: Tissue Homogenates
  104. Matrix metalloproteinase-8 facilitates neutrophil migration through the corneal stromal matrix by collagen degradation and production of the chemotactic peptide Pro-Gly-Pro.
    Authors: Lin M, Jackson P, Tester AM, Diaconu E, Overall CM, Blalock JE, Pearlman E
    Am. J. Pathol., 2008-06-13;173(1):144-53.
    Species: Mouse
    Sample Types: Tissue Homogenates
  105. Cytokine production by M-CSF- and GM-CSF-induced mouse bone marrow-derived macrophages upon coculturing with late apoptotic cells.
    Authors: Yamazaki T, Nagata K, Kobayashi Y
    Cell. Immunol., 2008-06-03;251(2):124-30.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  106. CD47 deficiency protects mice from lipopolysaccharide-induced acute lung injury and Escherichia coli pneumonia.
    Authors: Su X, Johansen M, Looney MR, Brown EJ, Matthay MA
    J. Immunol., 2008-05-15;180(10):6947-53.
    Species: Mouse
    Sample Types: BALF
  107. Functional Th1 cells are required for surgical adhesion formation in a murine model.
    Authors: Tzianabos AO, Holsti MA, Zheng XX, Stucchi AF, Kuchroo VK, Strom TB, Glimcher LH, Cruikshank WW
    J. Immunol., 2008-05-15;180(10):6970-6.
    Species: Mouse
    Sample Types: Peritoneal Lavage Fluid
  108. Functional roles for C5a receptors in sepsis.
    Authors: Rittirsch D, Flierl MA, Nadeau BA, Day DE, Huber-Lang M, Mackay CR, Zetoune FS, Gerard NP, Cianflone K, Kohl J, Gerard C, Sarma JV, Ward PA
    Nat. Med., 2008-05-04;14(5):551-7.
    Species: Mouse
    Sample Types: Plasma
  109. Role and regulation of adipokines during zymosan-induced peritoneal inflammation in mice.
    Authors: Pini M, Gove ME, Sennello JA, van Baal JW, Chan L, Fantuzzi G
    Endocrinology, 2008-05-01;149(8):4080-5.
    Species: Mouse
    Sample Types: Serum
  110. Neutrophil-toxin interactions promote antigen delivery and mucosal clearance of Streptococcus pneumoniae.
    Authors: Matthias KA, Roche AM, Standish AJ, Shchepetov M, Weiser JN
    J. Immunol., 2008-05-01;180(9):6246-54.
    Species: Mouse
    Sample Types: Nasal Lavage Fluid
  111. A novel mechanism for CCR4 in the regulation of macrophage activation in bleomycin-induced pulmonary fibrosis.
    Authors: Trujillo G, O'Connor EC, Kunkel SL, Hogaboam CM
    Am. J. Pathol., 2008-04-10;172(5):1209-21.
    Species: Mouse
    Sample Types: Tissue Homogenates
  112. Effects of epithelial and neutrophil CXCR2 on innate immunity and resistance to kidney infection.
    Authors: Svensson M, Irjala H, Svanborg C, Godaly G
    Kidney Int., 2008-04-09;74(1):81-90.
    Species: Mouse
    Sample Types: Urine
  113. Neutrophil chemokines KC and macrophage-inflammatory protein-2 are newly synthesized by tissue macrophages using distinct TLR signaling pathways.
    Authors: De Filippo K, Henderson RB, Laschinger M, Hogg N
    J. Immunol., 2008-03-15;180(6):4308-15.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  114. Matrix metalloproteinase-7 (matrilysin) controls neutrophil egress by generating chemokine gradients.
    Authors: Swee M, Wilson CL, Wang Y, McGuire JK, Parks WC
    J. Leukoc. Biol., 2008-03-11;83(6):1404-12.
    Species: Mouse
    Sample Types: Lavage Fluid
  115. Adverse functions of IL-17A in experimental sepsis.
    Authors: Flierl MA, Rittirsch D, Gao H, Hoesel LM, Nadeau BA, Day DE, Zetoune FS, Sarma JV, Huber-Lang MS, Ferrara JL, Ward PA
    FASEB J., 2008-02-25;22(7):2198-205.
    Species: Mouse
    Sample Types: Plasma
  116. Mouse models of rhinovirus-induced disease and exacerbation of allergic airway inflammation.
    Authors: Bartlett NW, Walton RP, Edwards MR, Aniscenko J, Caramori G, Zhu J, Glanville N, Choy KJ, Jourdan P, Burnet J, Tuthill TJ, Pedrick MS, Hurle MJ, Plumpton C, Sharp NA, Bussell JN, Swallow DM, Schwarze J, Guy B, Almond JW, Jeffery PK, Lloyd CM, Papi A, Killington RA, Rowlands DJ, Blair ED, Clarke NJ, Johnston SL
    Nat. Med., 2008-02-03;14(2):199-204.
    Species: Mouse
    Sample Types: BALF
  117. Peroxisome proliferator-activated receptor-gamma ligand, 15-deoxy-Delta12,14-prostaglandin J2, reduces neutrophil migration via a nitric oxide pathway.
    Authors: Napimoga MH, Vieira SM, Dal-Secco D, Freitas A, Souto FO, Mestriner FL, Alves-Filho JC, Grespan R, Kawai T, Ferreira SH, Cunha FQ
    J. Immunol., 2008-01-01;180(1):609-17.
    Species: Mouse
    Sample Types: Tissue Secretion
  118. Inflammasome-mediated production of IL-1beta is required for neutrophil recruitment against Staphylococcus aureus in vivo.
    Authors: Miller LS, Pietras EM, Uricchio LH, Hirano K, Rao S, Lin H, O'Connell RM, Iwakura Y, Cheung AL, Cheng G, Modlin RL
    J. Immunol., 2007-11-15;179(10):6933-42.
    Species: Mouse
    Sample Types: Tissue Homogenates
  119. IL-17 receptor signaling influences virus-induced corneal inflammation.
    Authors: Molesworth-Kenyon SJ, Yin R, Oakes JE, Lausch RN
    J. Leukoc. Biol., 2007-11-12;83(2):401-8.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  120. P-selectin glycoprotein ligand-1 regulates chemokine-dependent leukocyte recruitment in colonic ischemia-reperfusion.
    Authors: Santen S, Schramm R, Menger MD, Wang Y, Jeppsson B, Thorlacius H
    Inflamm. Res., 2007-11-01;56(11):452-8.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  121. Cathelicidin-deficient (Cnlp -/- ) mice show increased susceptibility to Pseudomonas aeruginosa keratitis.
    Authors: Huang LC, Reins RY, Gallo RL, McDermott AM
    Invest. Ophthalmol. Vis. Sci., 2007-10-01;48(10):4498-508.
    Species: Mouse
    Sample Types: Tissue Homogenates
  122. ST2 is essential for Th2 responsiveness and resistance to pseudomonas aeruginosa keratitis.
    Authors: Huang X, Du W, Barrett RP, Hazlett LD
    Invest. Ophthalmol. Vis. Sci., 2007-10-01;48(10):4626-33.
    Species: Mouse
    Sample Types: Tissue Homogenates
  123. The Duffy antigen receptor for chemokines in acute renal failure: A facilitator of renal chemokine presentation.
    Authors: Zarbock A, Schmolke M, Bockhorn SG, Scharte M, Buschmann K, Ley K, Singbartl K
    Crit. Care Med., 2007-09-01;35(9):2156-63.
    Species: Mouse
    Sample Types: Tissue Homogenates
  124. Keratinocyte growth factor protects against elastase-induced pulmonary emphysema in mice.
    Authors: Plantier L, Marchand-Adam S, Antico VG, Boyer L, De Coster C, Marchal J, Bachoual R, Mailleux A, Boczkowski J, Crestani B
    Am. J. Physiol. Lung Cell Mol. Physiol., 2007-08-31;293(5):L1230-9.
    Species: Mouse
    Sample Types: BALF
  125. Soluble vascular endothelial growth factor receptor-1 protects mice in sepsis.
    Authors: Tsao PN, Chan FT, Wei SC, Hsieh WS, Chou HC, Su YN, Chen CY, Hsu WM, Hsieh FJ, Hsu SM
    Crit. Care Med., 2007-08-01;35(8):1955-60.
    Species: Mouse
    Sample Types: Plasma
  126. Intrapulmonary delivery of bone marrow-derived mesenchymal stem cells improves survival and attenuates endotoxin-induced acute lung injury in mice.
    Authors: Gupta N, Su X, Popov B, Lee JW, Serikov V, Matthay MA
    J. Immunol., 2007-08-01;179(3):1855-63.
    Species: Mouse
    Sample Types: BALF
  127. Cannabinoid-2 receptor agonist HU-308 protects against hepatic ischemia/reperfusion injury by attenuating oxidative stress, inflammatory response, and apoptosis.
    Authors: Rajesh M, Pan H, Mukhopadhyay P, Batkai S, Osei-Hyiaman D, Hasko G, Liaudet L, Gao B, Pacher P
    J. Leukoc. Biol., 2007-07-25;82(6):1382-9.
    Species: Mouse
    Sample Types: Plasma
  128. Interleukin-1beta is the primary initiator of pulmonary inflammation following liver injury in mice.
    Authors: Glasgow SC, Ramachandran S, Blackwell TS, Mohanakumar T, Chapman WC
    Am. J. Physiol. Lung Cell Mol. Physiol., 2007-06-01;293(2):L491-6.
    Species: Mouse
    Sample Types: Serum
  129. Toll-like receptor 4 (TLR4)-dependent proinflammatory and immunomodulatory properties of the glycoinositolphospholipid (GIPL) from Trypanosoma cruzi.
    Authors: Medeiros MM, Peixoto JR, Oliveira AC, Cardilo-Reis L, Koatz VL, Van Kaer L, Previato JO, Mendonca-Previato L, Nobrega A, Bellio M
    J. Leukoc. Biol., 2007-05-31;82(3):488-96.
    Species: Mouse
    Sample Types: Peritoneal Fluid
  130. Mice lacking NKCC1 are protected from development of bacteremia and hypothermic sepsis secondary to bacterial pneumonia.
    Authors: Nguyen M, Pace AJ, Koller BH
    J. Exp. Med., 2007-05-21;204(6):1383-93.
    Species: Mouse
    Sample Types: Tissue Homogenates
  131. TLR2 is constitutively expressed within the kidney and participates in ischemic renal injury through both MyD88-dependent and -independent pathways.
    Authors: Shigeoka AA, Holscher TD, King AJ, Hall FW, Kiosses WB, Tobias PS, Mackman N, McKay DB
    J. Immunol., 2007-05-15;178(10):6252-8.
    Species: Mouse
    Sample Types: Tissue Homogenates
  132. CD44 regulates macrophage recruitment to the lung in lipopolysaccharide-induced airway disease.
    Authors: Hollingsworth JW, Li Z, Brass DM, Garantziotis S, Timberlake SH, Kim A, Hossain I, Savani RC, Schwartz DA
    Am. J. Respir. Cell Mol. Biol., 2007-04-19;37(2):248-53.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  133. Differential roles of p55 and p75 tumor necrosis factor receptors on stretch-induced pulmonary edema in mice.
    Authors: Wilson MR, Goddard ME, O&amp;apos;Dea KP, O'Dea KP, Choudhury S, Takata M
    Am. J. Physiol. Lung Cell Mol. Physiol., 2007-04-13;293(1):L60-8.
    Species: Mouse
    Sample Types: BALF
  134. Increased inflammation delays wound healing in mice deficient in collagenase-2 (MMP-8).
    Authors: Gutierrez-Fernandez A, Inada M, Balbin M, Fueyo A, Pitiot AS, Astudillo A, Hirose K, Hirata M, Shapiro SD, Noel A, Werb Z, Krane SM, Lopez-Otin C, Puente XS
    FASEB J., 2007-03-28;21(10):2580-91.
    Species: Mouse
    Sample Types: Tissue Homogenates
  135. Clostridium sordellii lethal toxin kills mice by inducing a major increase in lung vascular permeability.
    Authors: Geny B, Khun H, Fitting C, Zarantonelli L, Mazuet C, Cayet N, Szatanik M, Prevost MC, Cavaillon JM, Huerre M, Popoff MR
    Am. J. Pathol., 2007-03-01;170(3):1003-17.
    Species: Mouse
    Sample Types: Serum
  136. C3a is required for the production of CXC chemokines by tubular epithelial cells after renal ishemia/reperfusion.
    Authors: Thurman JM, Lenderink AM, Royer PA, Coleman KE, Zhou J, Lambris JD, Nemenoff RA, Quigg RJ, Holers VM
    J. Immunol., 2007-02-01;178(3):1819-28.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  137. Cathepsin-G interferes with clearance of Pseudomonas aeruginosa from mouse lungs.
    Authors: Sedor J, Hogue L, Akers K, Boslaugh S, Schreiber J, Ferkol T
    Pediatr. Res., 2007-01-01;61(1):26-31.
    Species: Mouse
    Sample Types: BALF
  138. Regulation of systemic and local neutrophil responses by G-CSF during pulmonary Pseudomonas aeruginosa infection.
    Authors: Gregory AD, Hogue LA, Ferkol TW, Link DC
    Blood, 2006-12-21;109(8):3235-43.
    Species: Mouse
    Sample Types: Epithelial Fluid
  139. A coagulation factor VII deficiency protects against acute inflammatory responses in mice.
    Authors: Xu H, Ploplis VA, Castellino FJ
    J. Pathol., 2006-12-01;210(4):488-96.
    Species: Mouse
    Sample Types: Plasma
  140. Delayed inflammatory response to primary pneumonic plague occurs in both outbred and inbred mice.
    Authors: Bubeck SS, Cantwell AM, Dube PH
    Infect. Immun., 2006-11-13;75(2):697-705.
    Species: Mouse
    Sample Types: BALF
  141. Local production of chemokines and prostaglandin E2 in the acute, chronic and recovery phase of murine experimental colitis.
    Authors: Drmotova M, Rehnstrom E, Jansson L
    Cytokine, 2006-11-07;35(5):275-83.
    Species: Mouse
    Sample Types: Tissue Homogenates
  142. Delayed inflammatory responses to endotoxin in fibrinogen-deficient mice.
    Authors: Cruz-Topete D, Iwaki T, Ploplis VA, Castellino FJ
    J. Pathol., 2006-11-01;210(3):325-33.
    Species: Mouse
    Sample Types: Plasma
  143. Src homology 2 domain-containing inositol 5-phosphatase 1 deficiency leads to a spontaneous allergic inflammation in the murine lung.
    Authors: Oh SY, Zheng T, Bailey ML, Barber DL, Schroeder JT, Kim YK, Zhu Z
    J. Allergy Clin. Immunol., 2006-10-23;119(1):123-31.
    Species: Mouse
    Sample Types: BALF
  144. The urokinase plasminogen activator receptor is crucially involved in host defense during acute pyelonephritis.
    Authors: Roelofs JJ, Rouschop KM, Teske GJ, Claessen N, Weening JJ, van der Poll T, Florquin S
    Kidney Int., 2006-10-11;70(11):1942-7.
    Species: Mouse
    Sample Types: Tissue Homogenates
  145. CD27 contributes to the early systemic immune response to Mycobacterium tuberculosis infection but does not affect outcome.
    Authors: Wieland CW, Kerver ME, Florquin S, Nolte MA, Borst J, van Lier R, van Oers MH, van der Poll T
    Int. Immunol., 2006-09-11;18(11):1531-9.
    Species: Mouse
    Sample Types: Tissue Homogenates
  146. GM-CSF and the impaired pulmonary innate immune response following hyperoxic stress.
    Authors: Baleeiro CE, Christensen PJ, Morris SB, Mendez MP, Wilcoxen SE, Paine R
    Am. J. Physiol. Lung Cell Mol. Physiol., 2006-08-04;291(6):L1246-55.
    Species: Mouse
    Sample Types: Tissue Homogenates
  147. Bone marrow-derived cells require a functional glucose 6-phosphate transporter for normal myeloid functions.
    Authors: Kim SY, Nguyen AD, Gao JL, Murphy PM, Mansfield BC, Chou JY
    J. Biol. Chem., 2006-08-04;281(39):28794-801.
    Species: Mouse
    Sample Types: Plasma
  148. The transcriptional response to lipopolysaccharide reveals a role for interferon-gamma in lung neutrophil recruitment.
    Authors: Burch LH, Yang IV, Whitehead GS, Chao FG, Berman KG, Schwartz DA
    Am. J. Physiol. Lung Cell Mol. Physiol., 2006-06-09;291(4):L677-82.
    Species: Mouse
    Sample Types: BALF
  149. The macrophage scavenger receptor SR-AI/II and lung defense against pneumococci and particles.
    Authors: Arredouani MS, Yang Z, Imrich A, Ning Y, Qin G, Kobzik L
    Am. J. Respir. Cell Mol. Biol., 2006-05-04;35(4):474-8.
    Species: Mouse
    Sample Types: BALF
  150. Adenosine A2A receptor inactivation increases survival in polymicrobial sepsis.
    Authors: Nemeth ZH, Csoka B, Wilmanski J, Xu D, Lu Q, Ledent C, Deitch EA, Pacher P, Spolarics Z, Hasko G
    J. Immunol., 2006-05-01;176(9):5616-26.
    Species: Mouse
    Sample Types: Plasma
  151. High expression of ligands for chemokine receptor CXCR2 in alveolar epithelial neoplasia induced by oncogenic kras.
    Authors: Wislez M, Fujimoto N, Izzo JG, Hanna AE, Cody DD, Langley RR, Tang H, Burdick MD, Sato M, Minna JD, Mao L, Wistuba I, Strieter RM, Kurie JM
    Cancer Res., 2006-04-15;66(8):4198-207.
    Species: Mouse
    Sample Types: Tissue Homogenates
  152. Human CXCR2 (hCXCR2) takes over functionalities of its murine homolog in hCXCR2 knockin mice.
    Authors: Mihara K, Smit MJ, Krajnc-Franken M, Gossen J, Rooseboom M, Dokter W
    Eur. J. Immunol., 2005-09-01;35(9):2573-82.
    Species: Mouse
    Sample Types: Serum
  153. Interleukin-17 as a recruitment and survival factor for airway macrophages in allergic airway inflammation.
    Authors: Sergejeva S, Ivanov S, Lotvall J, Linden A
    Am. J. Respir. Cell Mol. Biol., 2005-05-18;33(3):248-53.
    Species: Mouse
    Sample Types: BALF
  154. Endogenous interleukin-12 improves the early antimicrobial host response to murine Escherichia coli peritonitis.
    Authors: Weijer S, Florquin S, van der Poll T
    Shock, 2005-01-01;23(1):54-8.
    Species: Mouse
    Sample Types: Peritoneal Fluid
  155. The class A macrophage scavenger receptor attenuates CXC chemokine production and the early infiltration of neutrophils in sterile peritonitis.
    Authors: Cotena A, Platt N
    J. Immunol., 2004-11-15;173(10):6427-32.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  156. Regulation of Pseudomonas aeruginosa corneal infection in IL-1 beta converting enzyme (ICE, caspase-1) deficient mice.
    Authors: Thakur A, Barrett RP, McClellan S, Hazlett LD
    Curr. Eye Res., 2004-10-01;29(4):225-33.
    Species: Mouse
    Sample Types: Tissue Homogenates
  157. IL-22 increases the innate immunity of tissues.
    Authors: Wolk K, Kunz S, Witte E, Friedrich M, Asadullah K, Sabat R
    Immunity, 2004-08-01;21(2):241-54.
    Species: Mouse
    Sample Types: Plasma
  158. T cell-specific ablation of Fas leads to Fas ligand-mediated lymphocyte depletion and inflammatory pulmonary fibrosis.
    Authors: Hao Z, Hampel B, Yagita H, Rajewsky K
    J. Exp. Med., 2004-05-17;199(10):1355-65.
    Species: Mouse
    Sample Types: Serum
  159. Circulating CXC-chemokine concentrations in a murine intestinal ischemia-reperfusion model.
    Authors: Maheshwari A, Christensen RD, Calhoun DA
    Fetal Pediatr Pathol, 2004-03-01;23(2):145-57.
    Species: Mouse
    Sample Types: Serum
  160. Transcription regulation of TNF-alpha-early response genes by poly(ADP-ribose) polymerase-1 in murine heart endothelial cells.
    Authors: Carrillo A, Monreal Y, Ramirez P, Marin L, Parrilla P, Oliver FJ, Yelamos J
    Nucleic Acids Res., 2004-02-03;32(2):757-66.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  161. Chemokine and cytokine production during Orientia tsutsugamushi infection in mice.
    Authors: Koh YS, Yun JH, Seong SY, Choi MS, Kim IS
    Microb. Pathog., 2004-01-01;36(1):51-7.
    Species: Mouse
    Sample Types: Peritoneal Fluid
  162. CD40 plays a crucial role in lipopolysaccharide-induced acute lung injury.
    Authors: Hashimoto N, Kawabe T, Imaizumi K, Hara T, Okamoto M, Kojima K, Shimokata K, Hasegawa Y
    Am. J. Respir. Cell Mol. Biol., 2003-12-23;30(6):808-15.
    Species: Mouse
    Sample Types: BALF
  163. Thrombomodulin mutant mice with a strongly reduced capacity to generate activated protein C have an unaltered pulmonary immune response to respiratory pathogens and lipopolysaccharide.
    Authors: Rijneveld AW, Weijer S, Florquin S, Esmon CT, Meijers JC, Speelman P, Reitsma PH, ten Cate H, van der Poll T
    Blood, 2003-10-30;103(5):1702-9.
    Species: Mouse
    Sample Types: BALF
  164. Endogenous IL-17 as a mediator of neutrophil recruitment caused by endotoxin exposure in mouse airways.
    Authors: Miyamoto M, Prause O, Sjostrand M, Laan M, Lotvall J, Linden A
    J. Immunol., 2003-05-01;170(9):4665-72.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  165. Interleukin-10 negatively regulates local cytokine and chemokine production but does not influence antibacterial host defense during murine pneumococcal meningitis.
    Authors: Zwijnenburg PJ, van der Poll T, Florquin S, Roord JJ, van Furth AM
    Infect. Immun., 2003-04-01;71(4):2276-9.
    Species: Mouse
    Sample Types: Tissue Homogenates
  166. IL-17, produced by lymphocytes and neutrophils, is necessary for lipopolysaccharide-induced airway neutrophilia: IL-15 as a possible trigger.
    Authors: Ferretti S, Bonneau O, Dubois GR, Jones CE, Trifilieff A
    J. Immunol., 2003-02-15;170(4):2106-12.
    Species: Mouse
    Sample Types: BALF
  167. Selective I kappa B kinase expression in airway epithelium generates neutrophilic lung inflammation.
    Authors: Sadikot RT, Han W, Everhart MB, Zoia O, Peebles RS, Jansen ED, Yull FE, Christman JW, Blackwell TS
    J. Immunol., 2003-01-15;170(2):1091-8.
    Species: Mouse
    Sample Types: BALF
  168. Resident cell chemokine expression serves as the major mechanism for leukocyte recruitment during local inflammation.
    Authors: Garcia-Ramallo E, Marques T, Prats N, Beleta J, Kunkel SL, Godessart N
    J. Immunol., 2002-12-01;169(11):6467-73.
    Species: Mouse
    Sample Types: Air Pouch Exudate
  169. Cutting edge: myeloid differentiation factor 88 deficiency improves resistance against sepsis caused by polymicrobial infection.
    Authors: Weighardt H, Bê Ë„Æ%í, Kaiser-Moore S, Vabulas RM, Kirschning CJ, Wagner H, Holzmann B
    2002-09-15;169(6):2823-7.
    Species: Mouse
    Sample Types: Serum
  170. Neutrophil-mediated mycobacteriocidal immunity in the lung during Mycobacterium bovis BCG infection in C57BL/6 mice.
    Authors: Fulton SA, Reba SM, Martin TD, Boom WH
    Infect. Immun., 2002-09-01;70(9):5322-7.
    Species: Mouse
    Sample Types: BALF
  171. Overexpression of extracellular superoxide dismutase decreases lung injury after exposure to oil fly ash.
    Authors: Ghio AJ, 107303, Suliman HB, Carter JD, Abushamaa AM, Folz RJ
    MiR-99a alleviates apoptosis and extracellular matrix degradation in experimentally induced spine osteoarthritis by targeting FZD8, 2002-07-01;283(1):L211-8.
    Species: Mouse
    Sample Types: Tracheal Lavage Fluid
  172. Requirement of interleukin 17 receptor signaling for lung CXC chemokine and granulocyte colony-stimulating factor expression, neutrophil recruitment, and host defense.
    Authors: Ye P, Rodriguez FH, Kanaly S, Stocking KL, Schurr J, Schwarzenberger P, Oliver P, Huang W, Zhang P, Zhang J, Shellito JE, Bagby GJ, Nelson S, Charrier K, Peschon JJ, Kolls JK
    J. Exp. Med., 2001-08-20;194(4):519-27.
    Species: Mouse
    Sample Types: BALF
  173. The protein tyrosine kinase inhibitor AG126 prevents the massive microglial cytokine induction by pneumococcal cell walls.
    Authors: Hanisch UK, Prinz M, Angstwurm K, Hausler KG, Kann O, Kettenmann H, Weber JR
    Eur. J. Immunol., 2001-07-01;31(7):2104-15.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  174. Il-6 and its soluble receptor orchestrate a temporal switch in the pattern of leukocyte recruitment seen during acute inflammation.
    Authors: Hurst SM, Wilkinson TS, McLoughlin RM, Jones S, Horiuchi S, Yamamoto N, Rose-John S, Fuller GM, Topley N, Jones SA
    Immunity, 2001-06-01;14(6):705-14.
    Species: Mouse
    Sample Types: Peritoneal Lavage Fluid
  175. Rapid up-regulation of CXC chemokines in the airways after Ag-specific CD4+ T cell activation.
    Authors: Knott PG, Gater PR, Dunford PJ, Fuentes ME, Bertrand CP
    J. Immunol., 2001-01-15;166(2):1233-40.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  176. Inhibition of lipopolysaccharide-induced signal transduction in endotoxin-tolerized mouse macrophages: dysregulation of cytokine, chemokine, and toll-like receptor 2 and 4 gene expression.
    Authors: Medvedev AE, Kopydlowski KM, Vogel SN
    J. Immunol., 2000-06-01;164(11):5564-74.
    Species: Mouse
    Sample Types: Cell Culture Supernates

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Mouse CXCL2/MIP-2 Quantikine ELISA Kit
By Jim Hsiao on 12/04/2017
Sample Tested: Mouse lung BALF
Mouse CXCL2/MIP-2 Quantikine ELISA Kit MM200
Mouse CXCL2/MIP-2 Quantikine ELISA Kit
By Jun Xie on 08/04/2017
Sample Tested: Lung tissue