Mouse CXCL2/MIP-2 DuoSet ELISA Summary
* Provided that the recommended microplates, buffers, diluents, substrates and solutions are used, and the assay is run as summarized in the Assay Procedure provided.
This DuoSet ELISA Development kit contains the basic components required for the development of sandwich ELISAs to measure natural and recombinant mouse MIP-2. The suggested diluent is suitable for the analysis of most cell culture supernate samples. Diluents for complex matrices, such as serum and plasma, should be evaluated prior to use in this DuoSet.
Product Features
- Optimized capture and detection antibody pairings with recommended concentrations save lengthy development time
- Development protocols are provided to guide further assay optimization
- Assay can be customized to your specific needs
- Economical alternative to complete kits
Kit Content
- Capture Antibody
- Detection Antibody
- Recombinant Standard
- Streptavidin conjugated to horseradish-peroxidase (Streptavidin-HRP)
Other Reagents Required
DuoSet Ancillary Reagent Kit 2 (5 plates): (Catalog # DY008) containing 96 well microplates, plate sealers, substrate solution, stop solution, plate coating buffer (PBS), wash buffer, and Reagent Diluent Concentrate 2.
The components listed above may be purchased separately:
PBS: (Catalog # DY006), or 137 mM NaCl, 2.7 mM KCl, 8.1 mM Na2HPO4, 1.5 mM KH2PO4, pH 7.2 - 7.4, 0.2 µm filtered
Wash Buffer: (Catalog # WA126), or 0.05% Tween® 20 in PBS, pH 7.2-7.4
Reagent Diluent: (Catalog # DY995), or 1% BSA in PBS, pH 7.2-7.4, 0.2 µm filtered
Substrate Solution: 1:1 mixture of Color Reagent A (H2O2) and Color Reagent B (Tetramethylbenzidine) (Catalog # DY999)
Stop Solution: 2 N H2SO4 (Catalog # DY994)
Microplates: R&D Systems (Catalog # DY990)
Plate Sealers: ELISA Plate Sealers (Catalog # DY992)
Scientific Data
Product Datasheets
Preparation and Storage
Background: CXCL2/GRO beta/MIP-2/CINC-3
CXCL2/GRO beta, also called MIP-2 in mouse and CINC-3 in rat, is a member of the CXC chemokine family. Human CXCL2/GRO beta is 107 amino acids (aa) in length with a predicted molecular weight of 11 kDa. The mouse and rat orthologs share 70% and 71% aa sequence identity with the human protein, respectively. N-terminal aa 1-4 of CXCL2/GRO beta can be post-translationally cleaved which confers enhanced hematopoietic bioactivity. CXCL2/GRO beta is produced by a variety of cell types including monocytes and macrophages at sites of inflammation and is chemotactic for granulocytes, including neutrophils.
Assay Procedure
GENERAL ELISA PROTOCOL
Plate Preparation
- Dilute the Capture Antibody to the working concentration in PBS without carrier protein. Immediately coat a 96-well microplate with 100 μL per well of the diluted Capture Antibody. Seal the plate and incubate overnight at room temperature.
- Aspirate each well and wash with Wash Buffer, repeating the process two times for a total of three washes. Wash by filling each well with Wash Buffer (400 μL) using a squirt bottle, manifold dispenser, or autowasher. Complete removal of liquid at each step is essential for good performance. After the last wash, remove any remaining Wash Buffer by aspirating or by inverting the plate and blotting it against clean paper towels.
- Block plates by adding 300 μL Reagent Diluent to each well. Incubate at room temperature for a minimum of 1 hour.
- Repeat the aspiration/wash as in step 2. The plates are now ready for sample addition.
Assay Procedure
- Add 100 μL of sample or standards in Reagent Diluent, or an appropriate diluent, per well. Cover with an adhesive strip and incubate 2 hours at room temperature.
- Repeat the aspiration/wash as in step 2 of Plate Preparation.
- Add 100 μL of the Detection Antibody, diluted in Reagent Diluent, to each well. Cover with a new adhesive strip and incubate 2 hours at room temperature.
- Repeat the aspiration/wash as in step 2 of Plate Preparation.
- Add 100 μL of the working dilution of Streptavidin-HRP to each well. Cover the plate and incubate for 20 minutes at room temperature. Avoid placing the plate in direct light.
- Repeat the aspiration/wash as in step 2.
- Add 100 μL of Substrate Solution to each well. Incubate for 20 minutes at room temperature. Avoid placing the plate in direct light.
- Add 50 μL of Stop Solution to each well. Gently tap the plate to ensure thorough mixing.
- Determine the optical density of each well immediately, using a microplate reader set to 450 nm. If wavelength correction is available, set to 540 nm or 570 nm. If wavelength correction is not available, subtract readings at 540 nm or 570 nm from the readings at 450 nm. This subtraction will correct for optical imperfections in the plate. Readings made directly at 450 nm without correction may be higher and less accurate.
Citations for Mouse CXCL2/MIP-2 DuoSet ELISA
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Anti-Neuroinflammatory Effects of Ginkgo biloba Extract EGb 761 in LPS-Activated BV2 Microglial Cells
Authors: Sun, L;Apweiler, M;Tirkey, A;Klett, D;Normann, C;Dietz, GPH;Lehner, MD;Fiebich, BL;
International journal of molecular sciences
Species: Mouse
Sample Types: Cell Culture Supernates
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Rujin Jiedu decoction protects against influenza virus infection by modulating gut microbiota
Authors: Huang, Q;Yang, G;Tang, C;Dou, B;Hu, Y;Liu, H;Wu, X;Zhang, H;Wang, H;Xu, L;Yang, XD;Xu, Y;Zheng, Y;
Heliyon
Species: Mouse
Sample Types: Cell Culture Supernates
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Neutrophils and galectin-3 defend mice from lethal bacterial infection and humans from acute respiratory failure
Authors: Das, S;Kaminski, TW;Schlegel, BT;Bain, W;Hu, S;Patel, A;Kale, SL;Chen, K;Lee, JS;Mallampalli, RK;Kagan, VE;Rajasundaram, D;McVerry, BJ;Sundd, P;Kitsios, GD;Ray, A;Ray, P;
Nature communications
Species: Mouse
Sample Types: BALF
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Anti-Neuroinflammatory Effects of a Macrocyclic Peptide-Peptoid Hybrid in Lipopolysaccharide-Stimulated BV2 Microglial Cells
Authors: Sun, L;Wilke Saliba, S;Apweiler, M;Akmermer, K;Herlan, C;Grathwol, C;de Oliveira, ACP;Normann, C;Jung, N;Bräse, S;Fiebich, BL;
International journal of molecular sciences
Species: Mouse
Sample Types: Cell Culture Supernates
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Highly secreted tryptophanyl tRNA synthetase 1 as a potential theranostic target for hypercytokinemic severe sepsis
Authors: Kim, YT;Huh, JW;Choi, YH;Yoon, HK;Nguyen, TT;Chun, E;Jeong, G;Park, S;Ahn, S;Lee, WK;Noh, YW;Lee, KS;Ahn, HS;Lee, C;Lee, SM;Kim, KS;Suh, GJ;Jeon, K;Kim, S;Jin, M;
EMBO molecular medicine
Species: Mouse
Sample Types: Plasma, Peritoneal Lavage Fluid
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Pharmacological Inhibition and Genetic Deletion of Cystathionine Gamma-Lyase in Mice Protects against Organ Injury in Sepsis: A Key Role of Adhesion Molecules on Endothelial Cells
Authors: Manandhar, S;Chambers, S;Miller, A;Ishii, I;Bhatia, M;
International journal of molecular sciences
Species: Transgenic Mouse, Mouse
Sample Types: Tissue Homogenates
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The small non-coding RNA B11 regulates multiple facets of Mycobacterium abscessus virulence
Authors: Bar-Oz, M;Martini, MC;Alonso, MN;Meir, M;Lore, NI;Miotto, P;Riva, C;Angala, SK;Xiao, J;Masiello, CS;Misiakou, MA;Sun, H;Moy, JK;Jackson, M;Johansen, HK;Cirillo, DM;Shell, SS;Barkan, D;
PLoS pathogens
Species: Mouse
Sample Types: Tissue Homogenates
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CARD-only proteins regulate in�vivo inflammasome responses and ameliorate gout
Authors: S Devi, M Indramohan, E Jäger, J Carriere, LH Chu, L de Almeida, DR Greaves, C Stehlik, A Dorfleutne
Cell Reports, 2023-03-16;42(3):112265.
Species: Mouse
Sample Types: Cell Culture Supernates
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Tryptophan-dependent and -independent secretions of tryptophanyl- tRNA synthetase mediate innate inflammatory responses
Authors: TTT Nguyen, YH Choi, WK Lee, Y Ji, E Chun, YH Kim, JE Lee, HS Jung, JH Suh, S Kim, M Jin
Cell Reports, 2022-12-30;42(1):111905.
Species: Mouse
Sample Types: Lavage Fluid
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KDM6A Loss Recruits Tumor-Associated Neutrophils and Promotes Neutrophil Extracellular Trap Formation in Pancreatic Cancer
Authors: J Yang, L Jin, HS Kim, F Tian, Z Yi, K Bedi, M Ljungman, M Pasca di M, H Crawford, J Shi
Cancer Research, 2022-11-15;0(0):OF1-OF14.
Species: Mouse
Sample Types: Cell Culture Supernates
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AhR Mediated Activation of Pro-Inflammatory Response of RAW 264.7 Cells Modulate the Epithelial-Mesenchymal Transition
Authors: P Selvam, CM Cheng, HU Dahms, VK Ponnusamy, YY Sun
Toxics, 2022-10-27;10(11):.
Species: Mouse
Sample Types: Cell Culture Supernates
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Combinatorial microRNA Loading into Extracellular Vesicles for Increased Anti-Inflammatory Efficacy
Authors: AE Pottash, D Levy, A Jeyaram, L Kuo, SM Kronstadt, W Chao, SM Jay
Non-coding RNA, 2022-10-21;8(5):.
Species: Mouse
Sample Types: Plasma
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In vitro and in vivo Characterization of Host-Pathogen Interactions of the L3881 Candida albicans Clinical Isolate
Authors: PHF Sucupira, TR Moura, ILS Gurgel, TTP Pereira, ACB Padovan, MM Teixeira, D Bahia, FM Soriani
Frontiers in Microbiology, 2022-07-11;13(0):901442.
Species: Mouse
Sample Types: Cell Culture Supernates
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Artemisinin inhibits neutrophil and macrophage chemotaxis, cytokine production and NET release
Authors: HOJ Morad, S Luqman, LG Pinto, KP Cunningham, B Vilar, G Clayton, M Shankar-Ha, PA McNaughton
Scientific Reports, 2022-06-30;12(1):11078.
Species: Mouse
Sample Types: BALF
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The Therapeutic Treatment with the GAG-Binding Chemokine Fragment CXCL9(74-103) Attenuates Neutrophilic Inflammation and Lung Dysfunction during Klebsiella pneumoniae Infection in Mice
Authors: D Boff, RC Russo, H Crijns, VLS de Oliveir, MS Mattos, PE Marques, GB Menezes, AT Vieira, MM Teixeira, P Proost, FA Amaral
International Journal of Molecular Sciences, 2022-06-02;23(11):.
Species: Mouse
Sample Types: BALF
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Secreted NF-kappaB suppressive microbial metabolites modulate gut inflammation
Authors: R Giri, EC Hoedt, S Khushi, AA Salim, AS Bergot, V Schreiber, R Thomas, MA McGuckin, TH Florin, M Morrison, RJ Capon, P Ó Cuív, J Begun
Cell Reports, 2022-04-12;39(2):110646.
Species: Mouse
Sample Types: Cell Culture Supernates
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Effects of mango and mint pod-based e-cigarette aerosol inhalation on inflammatory states of the brain, lung, heart, and colon in mice
Authors: A Moshensky, CS Brand, H Alhaddad, J Shin, JA Masso-Silv, I Advani, D Gunge, A Sharma, S Mehta, A Jahan, S Nilaad, J Olay, W Gu, T Simonson, D Almarghala, J Pham, S Perera, K Park, R Al-Kolla, H Moon, S Das, M Byun, Z Shah, Y Sari, J Heller Bro, LE Crotty Ale
Elife, 2022-04-12;11(0):.
Species: Mouse
Sample Types: BALF
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Liposomal Dexamethasone Reduces A/H1N1 Influenza-Associated Morbidity in Mice
Authors: JW Kwon, H Quan, J Song, H Chung, D Jung, JJ Hong, YR Na, SH Seok
Frontiers in Microbiology, 2022-04-12;13(0):845795.
Species: Mouse
Sample Types: BALF
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Sevoflurane Dampens Acute Pulmonary Inflammation via the Adenosine Receptor A2B and Heme Oxygenase-1
Authors: KC Ngamsri, A Fuhr, K Schindler, M Simelitidi, M Hagen, Y Zhang, J Gamper-Tsi, FM Konrad
Cells, 2022-03-24;11(7):.
Species: Mouse
Sample Types: BALF
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The Crohn Disease-associated ATG16L1T300A polymorphism regulates inflammatory responses by modulating TLR- and NLR-mediated signaling
Authors: P Gao, H Liu, H Huang, Y Sun, B Jia, B Hou, X Zhou, W Strober, F Zhang
Autophagy, 2022-02-27;0(0):1-15.
Species: Human
Sample Types: Cell Culture Supernates
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Fibrotic lung disease inhibits innate immune responses to Staphylococcal pneumonia via impaired neutrophil and macrophage function
Authors: HI Warheit-Ni, SJ Edwards, S SenGupta, CA Parent, X Zhou, DN O'Dwyer, BB Moore
JCI Insight, 2022-02-22;0(0):.
Species: Mouse
Sample Types: Tissue Homogenates
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CXCR4 and CXCR7 Inhibition Ameliorates the Formation of Platelet-Neutrophil Complexes and Neutrophil Extracellular Traps through Adora2b Signaling
Authors: KC Ngamsri, RA Putri, C Jans, K Schindler, A Fuhr, Y Zhang, J Gamper-Tsi, S Ehnert, FM Konrad
International Journal of Molecular Sciences, 2021-12-17;22(24):.
Species: Mouse
Sample Types: Plasma
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Brain innate immune response via miRNA-TLR7 sensing in polymicrobial sepsis
Authors: L Zou, J He, L Gu, RA Shahror, Y Li, T Cao, S Wang, J Zhu, H Huang, F Chen, X Fan, J Wu, W Chao
Brain, Behavior, and Immunity, 2021-11-19;100(0):10-24.
Species: Mouse
Sample Types: Cell Culture Supernates
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PAD4 controls chemoattractant production and neutrophil trafficking in malaria
Authors: D Cela, SL Knackstedt, S Groves, CM Rice, JTW Kwon, B Mordmüller, B Amulic
Journal of leukocyte biology, 2021-11-10;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
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Signaling through Syk or CARD9 Mediates Species-Specific Anti-Candida Protection in Bone Marrow Chimeric Mice
Authors: E Zajta, K Csonka, A Tóth, L Tiszlavicz, T Németh, A Orosz, Á Novák, M Csikós, C Vágvölgyi, A Mócsai, A Gácser
MBio, 2021-08-31;12(4):e0160821.
Species: Mouse, Transgenic Mouse
Sample Types: Cell Culture Supernates
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Serum amyloid P component is an essential element of resistance against Aspergillus fumigatus
Authors: A Doni, R Parente, I Laface, E Magrini, C Cunha, FS Colombo, JF Lacerda, A Campos, SN Mapelli, F Petroni, R Porte, T Schorn, A Inforzato, T Mercier, K Lagrou, J Maertens, JD Lambris, B Bottazzi, C Garlanda, M Botto, A Carvalho, A Mantovani
Nature Communications, 2021-06-18;12(1):3739.
Species: Mouse
Sample Types: Cell Culture Supernates
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Resveratrol-Loaded Lipid-Core Nanocapsules Modulate Acute Lung Inflammation and Oxidative Imbalance Induced by LPS in Mice
Authors: MTP de Oliveir, DS Coutinho, SS Guterres, AR Pohlmann, PMRE Silva, MA Martins, A Bernardi
Pharmaceutics, 2021-05-10;13(5):.
Species: Mouse
Sample Types: Tissue Homogenates
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Oxygen conditions oscillating between hypoxia and hyperoxia induce different effects in the pulmonary endothelium compared to constant oxygen conditions
Authors: P Wohlrab, M Johann Dan, W Schaubmayr, A Tiboldi, K Krenn, K Markstalle, R Ullrich, K Ulrich Kle, V Tretter
Physiological Reports, 2021-02-01;9(3):e14590.
Species: Mouse
Sample Types: Cell Culture Supernates
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IL-10 and class 1 histone deacetylases act synergistically and independently on the secretion of proinflammatory mediators in alveolar macrophages
Authors: BA Stanfield, T Purves, S Palmer, B Sullenger, K Welty-Wolf, K Haines, S Agarwal, G Kasotakis
PLoS ONE, 2021-01-20;16(1):e0245169.
Species: Mouse
Sample Types: Cell Culture Supernates
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Repeated dermal application of the common preservative methylisothiazolinone triggers local inflammation, T cell influx, and prolonged mast cell-dependent tactile sensitivity in mice
Authors: JM Kline, E Arriaga-Go, T Yangdon, B Boo, J Landry, M Saldías-Mo, N Neamonitak, H Mengistu, S Silverio, H Zacheis, D Pasha, T Martinov, BT Fife, D Chatterjea
PLoS ONE, 2020-10-26;15(10):e0241218.
Species: Mouse
Sample Types: Cell Lysates
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Recombinant Protein-Based Nanoparticles: Elucidating their Inflammatory Effects In Vivo and their Potential as a New Therapeutic Format
Authors: L Gifre-Reno, E Ugarte-Ber, E Martens, L Boon, O Cano-Garri, E Martínez-N, T Luque, R Roca-Pinil, Ò Conchillo-, N Ferrer-Mir, A Villaverde, G Opdenakker, E Garcia-Fru, A Arís
Pharmaceutics, 2020-05-13;12(5):.
Species: Mouse
Sample Types: Complex Sample Type
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N-GSDMD trafficking to neutrophil organelles facilitates IL-1&beta release independently of plasma membrane pores and pyroptosis
Authors: M Karmakar, M Minns, EN Greenberg, J Diaz-Apont, K Pestonjama, JL Johnson, JK Rathkey, DW Abbott, K Wang, F Shao, SD Catz, GR Dubyak, E Pearlman
Nat Commun, 2020-05-05;11(1):2212.
Species: Mouse
Sample Types: Cell Culture Supernates
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Herbal Combinational Medication of Glycyrrhiza glabra, Agastache rugosa Containing Glycyrrhizic Acid, Tilianin Inhibits Neutrophilic Lung Inflammation by Affecting CXCL2, Interleukin-17/STAT3 Signal Pathways in a Murine Model of COPD
Authors: SH Kim, JH Hong, WK Yang, JH Geum, HR Kim, SY Choi, YM Kang, HJ An, YC Lee
Nutrients, 2020-03-27;12(4):.
Species: Mouse
Sample Types: BALF
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Nucleic Acid-Sensing Toll-Like Receptors Play a Dominant Role in Innate Immune Recognition of Pneumococci
Authors: A Famà, A Midiri, G Mancuso, C Biondo, G Lentini, R Galbo, MM Giardina, GV De Gaetano, L Romeo, G Teti, C Beninati
MBio, 2020-03-24;11(2):.
Species: Mouse
Sample Types: Tissue Lysates
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Allergic inflammation is initiated by IL-33-dependent crosstalk between mast cells and basophils
Authors: CL Hsu, KD Chhiba, R Krier-Burr, S Hosakoppal, S Berdnikovs, ML Miller, PJ Bryce
PLoS ONE, 2020-01-15;15(1):e0226701.
Species: Mouse
Sample Types: Cell Culture Supernates
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Evidence of CD40L/CD40 pathway involvement in experimental transfusion-related acute lung injury
Authors: S Tariket, H Hamzeh-Cog, S Laradi, CA Arthaud, MA Eyraud, T Bourlet, P Berthelot, O Garraud, F Cognasse
Sci Rep, 2019-08-29;9(1):12536.
Species: Human
Sample Types: Plasma
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The YIN and YANG of lipoproteins in developing and preventing infectious arthritis by Staphylococcus aureus
Authors: M Mohammad, MT Nguyen, C Engdahl, M Na, A Jarneborn, Z Hu, A Karlsson, R Pullerits, A Ali, F Götz, T Jin
PLoS Pathog., 2019-06-21;15(6):e1007877.
Species: Mouse
Sample Types: Tissue Homogenates
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Butyrate Protects Mice from Clostridium difficile-Induced Colitis through an HIF-1-Dependent Mechanism
Authors: JL Fachi, JS Felipe, LP Pral, BK da Silva, RO Corrêa, MCP de Andrade, DM da Fonseca, PJ Basso, NOS Câmara, ÉL de Sales E, F Dos Santos, SES Guima, AM Thomas, JC Setubal, YT Magalhães, FL Forti, T Candreva, HG Rodrigues, MB de Jesus, SR Consonni, ADS Farias, P Varga-Weis, MAR Vinolo
Cell Rep, 2019-04-16;27(3):750-761.e7.
Species: Mouse
Sample Types: Tissue Homogenates
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Macrophage-dependent neutrophil recruitment is impaired under conditions of increased intestinal permeability in JAM-A-deficient mice
Authors: AC Luissint, HC Williams, W Kim, S Flemming, V Azcutia, RS Hilgarth, MNO Leary, TL Denning, A Nusrat, CA Parkos
Mucosal Immunol, 2019-02-11;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
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Calcineurin inhibitor Tacrolimus impairs host immune response against urinary tract infection
Authors: D Emal, E Rampanelli, N Claessen, FJ Bemelman, JC Leemans, S Florquin, MC Dessing
Sci Rep, 2019-01-14;9(1):106.
Species: Mouse
Sample Types: Cell Culture Supernates
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Excessive neutrophil levels in the lung underlie the age-associated increase in influenza mortality
Authors: U Kulkarni, RL Zemans, CA Smith, SC Wood, JC Deng, DR Goldstein
Mucosal Immunol, 2019-01-07;12(2):545-554.
Species: Mouse
Sample Types: Cell Culture Supernates
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Protective Effect of Traditional Chinese Medicine Formula RP on Lung Microenvironment in Pre-Metastasis Stage of Breast Cancer
Authors: Y Ye, L Pei, C Wu, S Liu
Integr Cancer Ther, 2019-01-01;18(0):1534735419876.
Species: Mouse
Sample Types: BALF
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Role of a fluid-phase PRR in fighting an intracellular pathogen: PTX3 in Shigella infection
Authors: V Ciancarell, L Lembo-Fazi, I Paciello, AK Bruno, S Jaillon, S Berardi, M Barbagallo, S Meron-Suda, D Cohen, A Molinaro, G Rossi, C Garlanda, ML Bernardini
PLoS Pathog., 2018-12-07;14(12):e1007469.
Species: Mouse
Sample Types: Tissue Homogenates
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Intermittent Hypoxia Activates Duration-Dependent Protective and Injurious Mechanisms in Mouse Lung Endothelial Cells
Authors: P Wohlrab, L Soto-Gonza, T Benesch, MP Winter, IM Lang, K Markstalle, V Tretter, KU Klein
Front Physiol, 2018-12-06;9(0):1754.
Species: Mouse
Sample Types: Cell Culture Supernates
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Lipoteichoic acid anchor triggers Mincle to drive protective immunity against invasive group A Streptococcus infection
Authors: T Imai, T Matsumura, S Mayer-Lamb, CA Wells, E Ishikawa, SK Butcher, TC Barnett, MJ Walker, A Imamura, H Ishida, T Ikebe, T Miyamoto, M Ato, S Ohga, B Lepenies, NM van Sorge, S Yamasaki
Proc. Natl. Acad. Sci. U.S.A., 2018-10-23;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
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Extracellular ATP is a danger signal activating P2X7 receptor in a LPS mediated inflammation (ARDS/ALI)
Authors: S Cicko, TC Köhler, CK Ayata, T Müller, N Ehrat, A Meyer, M Hossfeld, A Zech, F Di Virgili, M Idzko
Oncotarget, 2018-07-17;9(55):30635-30648.
Species: Mouse
Sample Types: BALF
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Genetic ablation of histone deacetylase 2 leads to lung cellular senescence and lymphoid follicle formation in COPD/emphysema
Authors: IK Sundar, K Rashid, J Gerloff, J Rangel-Mor, D Li, I Rahman
FASEB J., 2018-04-09;0(0):fj201701518R.
Species: Mouse
Sample Types: Tissue Homogenates
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Nlrp12 Mediates Adverse Neutrophil Recruitment during Influenza Virus Infection
Authors: EE Hornick, B Banoth, AM Miller, ZR Zacharias, N Jain, ME Wilson, KN Gibson-Cor, KL Legge, GA Bishop, FS Sutterwala, SL Cassel
J. Immunol., 2017-12-27;0(0):.
Species: Mouse
Sample Types: Tissue Homogenates
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Microbiome-mediated neutrophil recruitment via CXCR2 and protection from amebic colitis
Authors: K Watanabe, CA Gilchrist, MJ Uddin, SL Burgess, MM Abhyankar, SN Moonah, Z Noor, JR Donowitz, BN Schneider, T Arju, E Ahmed, M Kabir, M Alam, R Haque, P Pramoonjag, B Mehrad, WA Petri
PLoS Pathog., 2017-08-17;13(8):e1006513.
Species: Mouse
Sample Types: Tissue Homogenates
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Acinetobacter baumannii Lipopolysaccharide Influences Adipokine Expression in 3T3-L1 Adipocytes
Authors: Y Unno, Y Sato, S Nishida, A Nakano, R Nakano, T Ubagai, Y Ono
Mediators Inflamm., 2017-07-05;2017(0):9039302.
Species: Mouse
Sample Types: Cell Culture Supernates
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?-bisabolol-loaded lipid-core nanocapsules reduce lipopolysaccharide-induced pulmonary inflammation in mice
Authors: APL D'Almeida, MT Pacheco de, ÉT de Souza, D de Sá Cout, BT Ciambarell, CR Gomes, T Terroso, SS Guterres, AR Pohlmann, PM Silva, MA Martins, A Bernardi
Int J Nanomedicine, 2017-06-19;12(0):4479-4491.
Species: Mouse
Sample Types: Tissue Homogenates
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Surface layer proteins from virulent Clostridium difficile ribotypes exhibit signatures of positive selection with consequences for innate immune response
Authors: M Lynch, TA Walsh, I Marszalows, AE Webb, M MacAogain, TR Rogers, H Windle, D Kelleher, MJ O'Connell, CE Loscher
BMC Evol. Biol, 2017-03-23;17(1):90.
Species: Mouse
Sample Types: Cell Culture Supernates
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The Carbohydrate Lectin Receptor, Dectin-1, Mediates Immune Response to Exserohilum rostratum
Infect. Immun, 2017-02-23;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
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Theranostic Nucleic Acid Binding Nanoprobe Exerts Anti-inflammatory and Cytoprotective Effects in Ischemic Injury
Authors: HH Chen, H Yuan, H Cho, Y Feng, S Ngoy, AT Kumar, R Liao, W Chao, L Josephson, DE Sosnovik
Theranostics, 2017-02-08;7(4):814-825.
Species: Mouse
Sample Types: Cell Culture Supernates
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Host-inherent variability influences the transcriptional response of Staphylococcus aureus during in vivo infection
Authors: R Th„nert, O Goldmann, A Beineke, E Medina
Nat Commun, 2017-02-03;8(0):14268.
Species: Mouse
Sample Types: Tissue Homogenates
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Chlamydial Lipoproteins Stimulate Toll-Like Receptors 1/2 Mediated Inflammatory Responses through MyD88-Dependent Pathway
Authors: Y Wang, Q Liu, D Chen, J Guan, L Ma, G Zhong, H Shu, X Wu
Front Microbiol, 2017-01-26;8(0):78.
Species: Human
Sample Types: Cell Culture Supernates
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Deletion of the Chemokine Binding Protein Gene from the Parapoxvirus Orf Virus Reduces Virulence and Pathogenesis in Sheep
Authors: SB Fleming, C McCaughan, Z Lateef, A Dunn, LM Wise, NC Real, AA Mercer
Front Microbiol, 2017-01-24;8(0):46.
Species: Mouse
Sample Types: Protein
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Anti-Inflammatory Effects of Rosiglitazone in Obesity-Impaired Wound Healing Depend on Adipocyte Differentiation
PLoS ONE, 2016-12-19;11(12):e0168562.
Species: Mouse
Sample Types: Cell Culture Supernates
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The Fli-1 transcription factor is a critical regulator for controlling the expression of chemokine C-X-C motif ligand 2 (CXCL2)
Authors: Xian K Zhang
Mol. Immunol., 2016-11-24;81(0):59-66.
Species: Mouse
Sample Types: Cell Culture Supernates
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Palmitate promotes inflammatory responses and cellular senescence in cardiac fibroblasts
Authors: Arne Yndestad
Biochim. Biophys. Acta, 2016-11-12;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
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TRAIL signaling is pro-inflammatory and pro-viral in a murine model of rhinovirus 1B infection
Authors: Joerg Mattes
Am. J. Physiol. Lung Cell Mol. Physiol., 2016-11-11;0(0):ajplung.00200.
Species: Mouse
Sample Types: Tissue Homogenates
-
Poly-N-acetyl glucosamine production by Staphylococcus epidermidis cells increases their in vivo pro-inflammatory effect
Infect Immun, 2016-09-19;0(0):.
Species: Mouse
Sample Types: Tissue Secretion
-
Klebsiella pneumoniae Siderophores Induce Inflammation, Bacterial Dissemination, and HIF-1? Stabilization during Pneumonia
MBio, 2016-09-13;7(5):.
Species: Mouse
Sample Types: Tissue Homogenates
-
NK cells regulate CXCR2+ neutrophil recruitment during acute lung injury
J Leukoc Biol, 2016-09-06;0(0):.
Species: Mouse
Sample Types: Tissue Homogenates
-
Host Inflammatory Response to Mosquito Bites Enhances the Severity of Arbovirus Infection
Authors: Marieke Pingen
Immunity, 2016-06-21;44(6):1455-69.
Species: Mouse
Sample Types: Tissue Homogenates
-
Plasminogen activator inhibitor-1 stimulates macrophage activation through Toll-like Receptor-4
Authors: Kamlesh K Gupta
Biochem Biophys Res Commun, 2016-06-15;0(0):.
Species: Mouse
Sample Types: Whole Cells
-
C1P Attenuates Lipopolysaccharide-Induced Acute Lung Injury by Preventing NF-?B Activation in Neutrophils
J Immunol, 2016-01-22;196(5):2319-26.
Species: Mouse
Sample Types: BALF
-
C1q Deficiency Promotes Pulmonary Vascular Inflammation and Enhances the Susceptibility of the Lung Endothelium to Injury.
Authors: Shah D, Romero F, Zhu Y, Duong M, Sun J, Walsh K, Summer R
J Biol Chem, 2015-10-20;290(49):29642-51.
Species: Mouse
Sample Types: BALF
-
The transcription factor ATF7 mediates lipopolysaccharide-induced epigenetic changes in macrophages involved in innate immunological memory.
Authors: Yoshida K, Maekawa T, Zhu Y, Renard-Guillet C, Chatton B, Inoue K, Uchiyama T, Ishibashi K, Yamada T, Ohno N, Shirahige K, Okada-Hatakeyama M, Ishii S
Nat Immunol, 2015-08-31;16(10):1034-43.
Species: Mouse
Sample Types: Serum
-
Influenza A virus-dependent remodeling of pulmonary clock function in a mouse model of COPD.
Authors: Sundar, Isaac K, Ahmad, Tanveer, Yao, Hongwei, Hwang, Jae-woon, Gerloff, Janice, Lawrence, B Paige, Sellix, Michael, Rahman, Irfan
Sci Rep, 2015-04-29;4(0):9927.
Species: Mouse
Sample Types: BALF
-
C-Type Lectin Receptor MCL Facilitates Mincle Expression and Signaling through Complex Formation.
Authors: Miyake Y, Masatsugu O, Yamasaki S
J Immunol, 2015-04-17;194(11):5366-74.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Mast cells play an important role in chlamydia pneumoniae lung infection by facilitating immune cell recruitment into the airway.
Authors: Chiba N, Shimada K, Chen S, Jones H, Alsabeh R, Slepenkin A, Peterson E, Crother T, Arditi M
J Immunol, 2015-03-09;194(8):3840-51.
Species: Mouse
Sample Types: BALF
-
Necroptosis suppresses inflammation via termination of TNF- or LPS-induced cytokine and chemokine production.
Authors: Kearney C, Cullen S, Tynan G, Henry C, Clancy D, Lavelle E, Martin S
Cell Death Differ, 2015-01-23;22(8):1313-27.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Vitamin D deficiency decreases survival of bacterial meningoencephalitis in mice.
Authors: Djukic M, Sostmann N, Bertsch T, Mecke M, Nessler S, Manig A, Hanisch U, Triebel J, Bollheimer L, Sieber C, Nau R
J Neuroinflammation, 2015-01-07;12(0):208.
Species: Mouse
Sample Types: Tissue Homogenates
-
A critical role for the TLR signaling adapter Mal in alveolar macrophage-mediated protection against Bordetella pertussis.
Authors: Bernard N, Finlay C, Tannahill G, Cassidy J, O'Neill L, Mills K
Mucosal Immunol, 2014-12-17;8(5):982-92.
Species: Mouse
Sample Types: Tissue Homogenates
-
No Impairment in host defense against Streptococcus pneumoniae in obese CPEfat/fat mice.
Authors: Mancuso P, O Brien E, Prano J, Goel D, Aronoff D
PLoS ONE, 2014-09-09;9(9):e106420.
Species: Mouse
Sample Types: BALF
-
Toll-like receptor 9 mediated responses in cardiac fibroblasts.
Authors: Ohm I, Alfsnes K, Belland Olsen M, Ranheim T, Sandanger O, Dahl T, Aukrust P, Finsen A, Yndestad A, Vinge L
PLoS ONE, 2014-08-15;9(8):e104398.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Chinese herbal medicine suppresses invasion-promoting capacity of cancer-associated fibroblasts in pancreatic cancer.
Authors: Chen, Lianyu, Qu, Chao, Chen, Hao, Xu, Litao, Qi, Qi, Luo, Jianmin, Wang, Kun, Meng, Zhiqiang, Chen, Zhen, Wang, Peng, Liu, Luming
PLoS ONE, 2014-04-29;9(4):e96177.
Species: Human
Sample Types: Cell Culture Supernates
-
Role of leukotriene A4 hydrolase aminopeptidase in the pathogenesis of emphysema.
Authors: Paige M, Wang K, Burdick M, Park S, Cha J, Jeffery E, Sherman N, Shim Y
J Immunol, 2014-04-25;192(11):5059-68.
Species: Mouse
Sample Types: BALF
-
Gene and protein expression in response to different growth temperatures and oxygen availability in Burkholderia thailandensis.
Authors: Peano C, Chiaramonte F, Motta S, Pietrelli A, Jaillon S, Rossi E, Consolandi C, Champion O, Michell S, Freddi L, Falciola L, Basilico F, Garlanda C, Mauri P, De Bellis G, Landini P
PLoS ONE, 2014-03-26;9(3):e93009.
Species: Mouse
Sample Types: Cell Culture Supernates, Cell Lysates
-
Hyaluronan digestion controls DC migration from the skin.
Authors: Muto, Jun, Morioka, Yasuhide, Yamasaki, Kenshi, Kim, Margaret, Garcia, Andrea, Carlin, Aaron F, Varki, Ajit, Gallo, Richard
J Clin Invest, 2014-03-01;124(3):1309-19.
Species: Mouse
Sample Types: Tissue Homogenates
-
Signaling via tumor necrosis factor receptor 1 but not Toll-like receptor 2 contributes significantly to hydrosalpinx development following Chlamydia muridarum infection.
Authors: Dong X, Liu Y, Chang X, Lei L, Zhong G
Infect Immun, 2014-02-18;82(5):1833-9.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Myeloid cell sirtuin-1 expression does not alter host immune responses to Gram-negative endotoxemia or Gram-positive bacterial infection.
Authors: Crotty Alexander, Laura E, Marsh, Brenda J, Timmer, Anjuli M, Lin, Ann E, Zainabadi, Kayvan, Czopik, Agnieszk, Guarente, Leonard, Nizet, Victor
PLoS ONE, 2013-12-26;8(12):e84481.
Species: Mouse
Sample Types: Plasma
-
The lung inflammation and skeletal muscle wasting induced by subchronic cigarette smoke exposure are not altered by a high-fat diet in mice.
Authors: Hansen, Michelle, Chen, Hui, Jones, Jessica, Langenbach, Shenna Y, Vlahos, Ross, Gualano, Rosa C, Morris, Margaret, Anderson, Gary P
PLoS ONE, 2013-11-19;8(11):e80471.
Species: Mouse
Sample Types: Tissue Homogenates
-
Milano summer particulate matter (PM10) triggers lung inflammation and extra pulmonary adverse events in mice.
Authors: Farina F, Sancini G, Battaglia C, Tinaglia V, Mantecca P, Camatini M, Palestini P
PLoS ONE, 2013-02-25;8(2):e56636.
Species: Mouse
Sample Types: BALF
-
The novel cytokine interleukin-33 activates acinar cell proinflammatory pathways and induces acute pancreatic inflammation in mice.
Authors: Kempuraj D, Twait E, Williard D, Yuan Z, Meyerholz D, Samuel I
PLoS ONE, 2013-02-13;8(2):e56866.
Species: Mouse
Sample Types: Tissue Homogenates
-
Genetic deletion of the HIF-1alpha isoform I.1 in T cells enhances antibacterial immunity and improves survival in a murine peritonitis model.
Authors: Georgiev P, Belikoff B, Hatfield S, Ohta A, Sitkovsky M, Lukashev D
Eur J Immunol, 2013-01-31;43(3):655-66.
Species: Mouse
Sample Types: Serum
-
Fecal lipocalin 2, a sensitive and broadly dynamic non-invasive biomarker for intestinal inflammation.
PLoS ONE, 2012-09-05;7(9):e44328.
Species: Mouse
Sample Types: Serum
-
Milk fat globule-epidermal growth factor-factor 8 attenuates neutrophil infiltration in acute lung injury via modulation of CXCR2.
Authors: Aziz M, Matsuda A, Yang WL, Jacob A, Wang P
J. Immunol., 2012-05-25;189(1):393-402.
Species: Mouse
Sample Types: Tissue Homogenates
-
Altered regulation of Toll-like receptor responses impairs antibacterial immunity in the allergic lung.
Authors: Habibzay, M, Saldana, J I, Goulding, J, Lloyd, C M, Hussell, T
Mucosal Immunol, 2012-05-02;5(5):524-34.
Species: Mouse
Sample Types: BALF
-
The role of alveolar epithelial cells in initiating and shaping pulmonary immune responses: communication between innate and adaptive immune systems.
Authors: Chuquimia OD, Petursdottir DH, Rahman MJ, Hartl K, Singh M, Fernandez C
PLoS ONE, 2012-02-29;7(2):e32125.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Role of Toll interleukin-1 receptor (IL-1R) 8, a negative regulator of IL-1R/Toll-like receptor signaling, in resistance to acute Pseudomonas aeruginosa lung infection.
Authors: Veliz Rodriguez T, Moalli F, Polentarutti N, Paroni M, Bonavita E, Anselmo A, Nebuloni M, Mantero S, Jaillon S, Bragonzi A, Mantovani A, Riva F, Garlanda C
Infect. Immun., 2011-10-24;80(1):100-9.
Species: Mouse
Sample Types: Serum
-
Local delivery of GM-CSF protects mice from lethal pneumococcal pneumonia.
Authors: Steinwede K, Tempelhof O, Bolte K, Maus R, Bohling J, Ueberberg B, Langer F, Christman JW, Paton JC, Ask K, Maharaj S, Kolb M, Gauldie J, Welte T, Maus UA
J. Immunol., 2011-10-14;187(10):5346-56.
Species: Mouse
Sample Types: BALF
-
Leukocyte ADAM17 Regulates Acute Pulmonary Inflammation.
Authors: Arndt PG, Strahan B, Wang Y, Long C, Horiuchi K, Walcheck B
PLoS ONE, 2011-05-16;6(5):e19938.
Species: Mouse
Sample Types: BALF
-
Lung-targeted overexpression of the NF-kappaB member RelB inhibits cigarette smoke-induced inflammation.
Authors: McMillan DH, Baglole CJ, Thatcher TH, Maggirwar S, Sime PJ, Phipps RP
Am. J. Pathol., 2011-05-05;179(1):125-33.
Species: Mouse
Sample Types: BALF
-
The Therapeutic Potential of the Humoral Pattern Recognition Molecule PTX3 in Chronic Lung Infection Caused by Pseudomonas aeruginosa.
Authors: Moalli F, Paroni M, Veliz Rodriguez T, Riva F, Polentarutti N, Bottazzi B, Valentino S, Mantero S, Nebuloni M, Mantovani A, Bragonzi A, Garlanda C
J. Immunol., 2011-03-25;186(9):5425-34.
Species: Mouse
Sample Types: Tissue Homogenates
-
Recombinant human tissue factor pathway inhibitor exerts anticoagulant, anti-inflammatory and antimicrobial effects in murine pneumococcal pneumonia.
Authors: Van Den Boogaard FE, Brands X, Schultz MJ, Levi M, Roelofs JJ, Van 't Veer C, van der Poll T
J. Thromb. Haemost., 2011-01-01;9(1):122-32.
Species: Mouse
Sample Types: BALF
-
Phosphoinositide 3-kinase gamma plays a critical role in bleomycin-induced pulmonary inflammation and fibrosis in mice.
Authors: Russo RC, Garcia CC, Barcelos LS, Rachid MA, Guabiraba R, Roffe E, Souza AL, Sousa LP, Mirolo M, Doni A, Cassali GD, Pinho V, Locati M, Teixeira MM
J. Leukoc. Biol., 2010-11-02;89(2):269-82.
Species: Mouse
Sample Types: Tissue Homogenates
-
Distinct roles of hepatocyte- and myeloid cell-derived IL-1 receptor antagonist during endotoxemia and sterile inflammation in mice.
Authors: Lamacchia C, Palmer G, Bischoff L, Rodriguez E, Talabot-Ayer D, Gabay C
J. Immunol., 2010-07-16;185(0):2516-24.
Species: Mouse
Sample Types: Serum
-
Inflammatory chemokine release of astrocytes in vitro is reduced by all-trans retinoic acid.
Authors: van Neerven S, Regen T, Wolf D, Nemes A, Johann S, Beyer C, Hanisch UK, Mey J
J. Neurochem., 2010-06-16;114(5):1511-26.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Ligands of the receptor for advanced glycation end products, including high-mobility group box 1, limit bacterial dissemination during Escherichia coli peritonitis.
Authors: van Zoelen MA, Achouiti A, Schmidt AM, Yang H, Florquin S, Tracey KJ, van der Poll T
Crit. Care Med., 2010-06-01;38(6):1414-22.
Species: Mouse
Sample Types: Peritoneal Fluid
-
Impact of adiponectin deficiency on pulmonary responses to acute ozone exposure in mice.
Authors: Zhu M, Hug C, Kasahara DI
Am. J. Respir. Cell Mol. Biol., 2009-11-13;43(4):487-97.
Species: Mouse
Sample Types: BALF
-
Spatiotemporal expression of chemokines and chemokine receptors in experimental anti-myeloperoxidase antibody-mediated glomerulonephritis.
Authors: van der Veen BS, Petersen AH, Belperio JA, Satchell SC, Mathieson PW, Molema G, Heeringa P
Clin. Exp. Immunol., 2009-10-01;158(1):143-53.
Species: Mouse
Sample Types: Tissue Homogenates
-
Role of endothelial TLR4 for neutrophil recruitment into central nervous system microvessels in systemic inflammation.
Authors: Zhou H, Andonegui G, Wong CH, Kubes P
J. Immunol., 2009-09-28;183(8):5244-50.
Species: Mouse
Sample Types: Plasma
-
TREM-1 activation alters the dynamics of pulmonary IRAK-M expression in vivo and improves host defense during pneumococcal pneumonia.
Authors: Lagler H, Sharif O, Haslinger I, Matt U, Stich K, Furtner T, Doninger B, Schmid K, Gattringer R, de Vos AF, Knapp S
J. Immunol., 2009-07-13;183(3):2027-36.
Species: Mouse
Sample Types: Tissue Homogenates
-
Expression of inflammatory mediators in the otitis media induced by Helicobacter pylori antigen in mice.
Authors: Kariya S, Okano M, Fukushima K, Nomiya S, Kataoka Y, Nomiya R, Akagi H, Nishizaki K
Clin. Exp. Immunol., 2008-08-22;154(1):134-40.
Species: Mouse
Sample Types: Middle Ear Lavage Fluid
-
The chemokine receptors CXCR1/CXCR2 modulate antigen-induced arthritis by regulating adhesion of neutrophils to the synovial microvasculature.
Authors: Coelho FM, Pinho V, Amaral FA, Sachs D, Costa VV, Rodrigues DH, Vieira AT, Silva TA, Souza DG, Bertini R, Teixeira AL, Teixeira MM
Arthritis Rheum., 2008-08-01;58(8):2329-37.
Species: Mouse
Sample Types: Tissue Homogenates
-
Neurokinin A engages neurokinin-1 receptor to induce NF-kappaB-dependent gene expression in murine macrophages: implications of ERK1/2 and PI 3-kinase/Akt pathways.
Authors: Sun J, Ramnath RD, Tamizhselvi R, Bhatia M
Am. J. Physiol., Cell Physiol., 2008-07-02;295(3):C679-91.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Administration of a synthetic TLR4 agonist protects mice from pneumonic tularemia.
Authors: Lembo A, Pelletier M, Iyer R, Timko M, Dudda JC, West TE, Wilson CB, Hajjar AM, Skerrett SJ
J. Immunol., 2008-06-01;180(11):7574-81.
Species: Mouse
Sample Types: Tissue Homogenates
-
Surfactant protein D alters allergic lung responses in mice and human subjects.
Authors: Brandt EB, Mingler MK, Stevenson MD, Wang N, Khurana Hershey GK, Whitsett JA, Rothenberg ME
J. Allergy Clin. Immunol., 2008-03-19;121(5):1140-1147.e2.
Species: Mouse
Sample Types: BALF
-
Scavenging roles of chemokine receptors: chemokine receptor deficiency is associated with increased levels of ligand in circulation and tissues.
Authors: Cardona AE, Sasse ME, Liu L, Cardona SM, Mizutani M, Savarin C, Hu T, Ransohoff RM
Blood, 2008-03-17;112(2):256-63.
Species: Mouse
Sample Types: Tissue Homogenates
-
An age-associated increase in pulmonary inflammation after burn injury is abrogated by CXCR2 inhibition.
Authors: Nomellini V, Faunce DE, Gomez CR, Kovacs EJ
J. Leukoc. Biol., 2008-03-13;83(6):1493-501.
Species: Mouse
Sample Types: Tissue Homogenates
-
Caspase-1 contributes to Chlamydia trachomatis-induced upper urogenital tract inflammatory pathologies without affecting the course of infection.
Authors: Cheng W, Shivshankar P, Li Z, Chen L, Yeh IT, Zhong G
Infect. Immun., 2007-11-19;76(2):515-22.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Involvement of vitronectin in lipopolysaccaride-induced acute lung injury.
Authors: Tsuruta Y, Park YJ, Siegal GP, Liu G, Abraham E
J. Immunol., 2007-11-15;179(10):7079-86.
Species: Mouse
Sample Types: Tissue Homogenates
-
Minocycline modulates neuroinflammation independently of its antimicrobial activity in staphylococcus aureus-induced brain abscess.
Authors: Kielian T, Esen N, Liu S, Phulwani NK, Syed MM, Phillips N, Nishina K, Cheung AL, Schwartzman JD, Ruhe JJ
Am. J. Pathol., 2007-08-23;171(4):1199-214.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Neurokinin-1 receptor antagonist treatment protects mice against lung injury in polymicrobial sepsis.
Authors: Hegde A, Zhang H, Moochhala SM, Bhatia M
J. Leukoc. Biol., 2007-06-12;82(3):678-85.
Species: Mouse
Sample Types: Plasma
-
Nod1-mediated innate immune recognition of peptidoglycan contributes to the onset of adaptive immunity.
Authors: Fritz JH, Le Bourhis L, Sellge G, Magalhaes JG, Fsihi H, Kufer TA, Collins C, Viala J, Ferrero RL, Girardin SE, Philpott DJ
Immunity, 2007-04-12;26(4):445-59.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Role of Toll-like receptor 2 in recognition of Legionella pneumophila in a murine pneumonia model.
Authors: Fuse ET, Tateda K, Kikuchi Y, Matsumoto T, Gondaira F, Azuma A, Kudoh S, Standiford TJ, Yamaguchi K
J. Med. Microbiol., 2007-03-01;56(0):305-12.
Species: Mouse
Sample Types: Tissue Homogenates
-
Role of mesothelial cell-derived granulocyte colony-stimulating factor in interleukin-17-induced neutrophil accumulation in the peritoneum.
Authors: Witowski J, Ksiazek K, Warnecke C, Kuzlan M, Korybalska K, Tayama H, Wisniewska-Elnur J, Pawlaczyk K, Trominska J, Breborowicz A, Jorres A
Kidney Int., 2007-01-17;71(6):514-25.
Species: Mouse
Sample Types: Peritoneal Lavage Fluid
-
TLR4 mediates vaccine-induced protective cellular immunity to Bordetella pertussis: role of IL-17-producing T cells.
Authors: Higgins SC, Jarnicki AG, Lavelle EC, Mills KH
J. Immunol., 2006-12-01;177(11):7980-9.
Species: Mouse
Sample Types: Tissue Homogenates
-
Effects of dexamethazone on LPS-induced activationand migration of mouse dendritic cells revealed by a genome-wide transcriptional analysis.
Authors: Vizzardelli C, Pavelka N, Luchini A, Zanoni I, Bendickson L, Pelizzola M, Beretta O, Foti M, Granucci F, Nilsen-Hamilton M, Ricciardi-Castagnoli P
Eur. J. Immunol., 2006-06-01;36(6):1504-15.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Mucosal administration of CpG oligodeoxynucleotide elicits strong CC and CXC chemokine responses in the vagina and serves as a potent Th1-tilting adjuvant for recombinant gD2 protein vaccination against genital herpes.
Authors: Tengvall S, Lundqvist A, Eisenberg RJ, Cohen GH, Harandi AM
J. Virol., 2006-06-01;80(11):5283-91.
Species: Mouse
Sample Types: Tissue Homogenates
-
Differential involvement of TLR2 and TLR4 in host survival during pulmonary infection with Chlamydia pneumoniae.
Authors: Rodriguez N, Wantia N, Fend F, Durr S, Wagner H, Miethke T
Eur. J. Immunol., 2006-05-01;36(5):1145-55.
Species: Mouse
Sample Types: Tissue Homogenates
-
The pulmonary and hepatic immune microenvironment and its contribution to the early systemic inflammation following blunt chest trauma.
Authors: Perl M, Gebhard F, Braumuller S, Tauchmann B, Bruckner UB, Kinzl L, Knoferl MW
Crit. Care Med., 2006-04-01;34(4):1152-9.
Species: Mouse
Sample Types: BALF
-
Toll-like receptor 4 signaling leads to neutrophil migration impairment in polymicrobial sepsis.
Authors: Alves-Filho JC, de Freitas A, Russo M, Cunha FQ
Crit. Care Med., 2006-02-01;34(2):461-70.
Species: Mouse
Sample Types: Tissue Homogenates
-
Increased pulmonary responses to acute ozone exposure in obese db/db mice.
Authors: Lu FL, Johnston RA, Flynt L, Theman TA, Terry RD, Schwartzman IN, Lee A, Shore SA
Am. J. Physiol. Lung Cell Mol. Physiol., 2005-12-22;290(5):L856-65.
Species: Mouse
Sample Types: Serum
-
An essential role for non-bone marrow-derived cells in control of Pseudomonas aeruginosa pneumonia.
Authors: Hajjar AM, Harowicz H, Liggitt HD, Fink PJ, Wilson CB, Skerrett SJ
Am. J. Respir. Cell Mol. Biol., 2005-08-11;33(5):470-5.
Species: Mouse
Sample Types: Tissue Homogenates
-
Tissue inhibitor of metalloproteinase-1 deficiency amplifies acute lung injury in bleomycin-exposed mice.
Authors: Kim KH, Burkhart K, Chen P, Frevert CW, Randolph-Habecker J, Hackman RC, Soloway PD, Madtes DK
Am. J. Respir. Cell Mol. Biol., 2005-06-09;33(3):271-9.
Species: Mouse
Sample Types: BALF
-
Pyocyanin production by Pseudomonas aeruginosa induces neutrophil apoptosis and impairs neutrophil-mediated host defenses in vivo.
Authors: Allen L, Dockrell DH, Pattery T, Lee DG, Cornelis P, Hellewell PG, Whyte MK
J. Immunol., 2005-03-15;174(6):3643-9.
Species: Mouse
Sample Types: BALF
-
Toll-like receptor 2 (TLR2) mediates astrocyte activation in response to the Gram-positive bacterium Staphylococcus aureus.
Authors: Esen N, Tanga FY, DeLeo JA, Kielian T
J. Neurochem., 2004-02-01;88(3):746-58.
Species: Mouse
Sample Types: Cell Culture Supernates
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