Mouse CD4 APC-conjugated Antibody Summary
Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Scientific Data
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Detection of CD4 in Mouse Splenocytes by Flow Cytometry. Mouse splenocytes were stained with Rat Anti-Mouse CD3 PE-conjugated Monoclonal Antibody (Catalog # FAB4841P) and either (A) Rat Anti-Mouse CD4 APC-conjugated Monoclonal Antibody (Catalog # FAB554A) or (B) Rat IgG2BAllophycocyanin Isotype Control (Catalog # IC013A). View our protocol for Staining Membrane-associated Proteins.
Preparation and Storage
- 12 months from date of receipt, 2 to 8 °C as supplied.
Background: CD4
CD4 is a type I membrane glycoprotein belonging to the immunoglobulin superfamily. It is expressed predominantly on thymocytes and a subset of mature T lymphocytes. CD4 functions in collaboration with the T cell receptor in the recognition of peptide antigens that are presented by class II major histocompatibility complexes. CD4 also has been shown to be a coreceptor of HIV entry and specifically binds gp120, the external envelope glycoprotein of HIV.
Product Datasheets
Citations for Mouse CD4 APC-conjugated Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Citations: Showing 1 - 4
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Coenzyme Q10 exhibits anti-inflammatory and immune-modulatory thereby decelerating the occurrence of experimental cerebral malaria
Authors: Nyariki, JN;Kimani, NM;Kibet, PS;Kinuthia, GK;Isaac, AO;
Molecular and biochemical parasitology
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
PD-L2 Blockade Exacerbates Liver Lesion in Mice Infected with Capillaria hepatica through Reducing Alternatively Activated Macrophages
Authors: M Huang, X Li, X Zheng, F Wang, Y Zou, L Wang
Tropical medicine and infectious disease, 2023-01-06;8(1):.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
Mitigation of Tacrolimus-Associated Nephrotoxicity by PLGA Nanoparticulate Delivery Following Multiple Dosing to Mice while Maintaining its Immunosuppressive Activity
Authors: A Alshamsan, Z Binkhathla, MA Kalam, W Qamar, H Kfouri, M Alghonaim, A Lavasanifa
Sci Rep, 2020-04-21;10(1):6675.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
Ouabain Attenuates Sepsis-Induced Immunosuppression in Mice by Activation and Anti-Apoptosis of T Cells
Authors: R Niu, H Gao, Y Zhou, J Zhang
Med. Sci. Monit., 2018-05-02;24(0):2720-2727.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry
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