Home / Additional 5-HT-Related Compounds / Methylergometrine maleate

Methylergometrine maleate

Catalog #: 0549
2 Citations Datasheet
Catalog # Availability Size / Price Qty
0549/50
0549/250
Methylergometrine maleate | CAS No. 57432-61-8 | Additional 5-HT-Related Compounds
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Description: Active metabolite of methysergide (Cat. No. 1064)
Alternative Names: Methylergonovine maleate

Chemical Name: [8β(S)]-9,10-Didehydro-N-[1-(hydroxymethyl)propyl]-6-methylergoline-8-carboxamide maleate

Purity: ≥98%

Product Details
Citations (2)
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Reviews
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

Methylergometrine maleate is an active metabolite of methysergide (Cat. No. 1064); uterotonic agent and oxytocic.

Technical Data

M.Wt:
455.51
Formula:
C20H25N3O2.C4H4O4
Solubility:
Soluble to 25 mM in water
Purity:
≥98%
Storage:
Desiccate at RT
CAS No:
57432-61-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.
    Fox JT, Sakamuru S, Huang R
    Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8.
  2. Actions of non-peptide ergot alkaloids at 5-HT1-like and 5-HT2 receptors mediating vascular smooth muscle contraction.
    MacLennan and Martin
    Naunyn Schmiedebergs Arch.Pharmacol., 1990;342:120
  3. 5-Hydroxytryptamine (5-HT) contracts the guinea-pig isolated iliac artery via 5-HT1-like and 5-HT2 receptors.
    Pertz
    Naunyn Schmiedebergs Arch.Pharmacol., 1993;348:558
  4. Methylergometrine, an active metabolite of methysergide.
    Muller-Schweinitzer and Tapparelli
    Cephalalgia, 1986;6:35

Product Datasheets

Citations for Methylergometrine maleate

The citations listed below are publications that use Tocris products. Selected citations for Methylergometrine maleate include:

2 Citations: Showing 1 - 2

  1. Ergot Alkaloids (Re)generate New Leads as Antiparasitics.
    Authors: Chan Et al.
    Cell Signal  2015;9:e0004063
  2. Polysynaptic excitatory postsynaptic potentials that trigger spasms after spinal cord injury in rats are inhibited by 5-HT1B and 5-HT1F receptors.
    Authors: Murray Et al.
    J Neurophysiol  2011;106:925

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