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Methoxyluteolin

Catalog #: 7320 Datasheet
Catalog # Availability Size / Price Qty
7320/50
Methoxyluteolin | CAS No. 855-97-0 | Cytokine Compounds
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Description: Inhibitor of pro-inflammatory mediator release from mast cells

Chemical Name: 2-(3,4-Dimethoxyphenyl)-5,7-dimethoxy-4H-1-benzopyran-4-one

Purity: ≥98%

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Biological Activity

Methoxyluteolin inhibits release of pro-inflammatory mediators from mast cells and decreases gene expression and release of TNF, VEGF and IL-8/CXCL8. The product also significantly inhibits IL-33 stimulated expression and release of CCL5 and CCL2. Methoxyluteolin pretreatment of LAD2 mast cells decreases gene expression of TNF, CXCL8 and VEGF in response to neurotensin or substance P via mTOR activation.

Technical Data

M.Wt:
342.35
Formula:
C19H18O6
Solubility:
Soluble to 20 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
855-97-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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