Mandi
Chemical Name: 4-Chloro-N-[2-[3-methoxy-4-(2-propyn-1-yloxy)phenyl]ethyl]-α-(2-propyn-1-yloxy)benzeneacetamide
Purity: ≥98%
Biological Activity
Mandi is a chemical inducer of proximity (CIP) in vivo and in vitro (EC50 = 0.43 μM in a luciferase gene expression assay). Mandi induces complex formation between PYR1Mandi, a mutant of Abscisic Acid (Cat. No. 6554) receptor PYR1, and Abscisic Acid insensitive (ABI). Mandi may be used to induce protein colocalization and interaction. It is non-toxic, orthogonal to mammalian processes and other CIPs, and highly cell permeable.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets
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