L-BMAA hydrochloride
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Description: Neurotoxic amino acid
Chemical Name: 3-(Methylamino)-L-alanine hydrochloride
Biological Activity
L-BMAA hydrochloride is a neurotoxic glutamate agonist originally isolated from Cycas circinalis. Implicated in the pathogenesis of amyotrophic lateral sclerosis-Parkinsonism-dementia complex of Guam (Guam ALS-PD).Technical Data
M.Wt:
154.6
Formula:
C4H10N2O2.HCl
Solubility:
Soluble to 60 mM in water
Storage:
Store at -20°C
CAS No:
16012-55-8
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Neurotoxicity of β-N-methylamino-L-alanine (BMAA) and β-N-oxalylamino-L-alanine (BOAA) on cultured cortical neurons.
Weiss et al.
Brain Res., 1989;497:64 -
The preparation of L- and D-α-amino-β<-methylaminopropionic acids and the identification of the compound isolated from Cycas circinalis as the L-isomer.
Vega et al.
Phytochemistry, 1968;7:1885
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