Klotho-derived peptide 6
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Description: Wnt/β-catenin signaling inhibitor
Purity: ≥95%
Biological Activity
Klotho-derived peptide 6 is a β-catenin signaling inhibitor. Binds to and sequesters Wnt ligands in vitro; prevents expression of Wnt1-induced fibronectin and α-smooth muscle action. In an in vivo mouse model of diabetic kidney disease, Klotho-derived peptide 6 reduces kidney injury, improves survival and prevents accumulation of fibronectin and collagen IV in glomeruli.Technical Data
M.Wt:
3491.87
Formula:
C159H232N46O44
Sequence:
QPVVTLYHWDLPQRLQDAYGGWANRALADH
Solubility:
Soluble to 1 mg/ml in water
Purity:
≥95%
Storage:
Store at -20°C
CAS No:
2102414-23-1
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
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