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Janelia Fluor® 646b, Maleimide

Catalog #: 8158 Datasheet
Catalog # Availability Size / Price Qty
8158/200U
Janelia Fluor® 646b, Maleimide | CAS No. 2634129-70-5 | Fluorescent Dyes
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Description: Blinking fluorescent dye (Reactive group: maleimide). Application: super resolution microscopy (SRM) including SMLM

Chemical Name: 3,7-Di(azetidin-1-yl)-N-(2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethyl)-5,5-dimethyl-3'H,5H-spiro[dibenzo[b,e]siline-10,1'-isobenzofuran]-6'-carboxamide

Purity: ≥90%

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Biological Activity

Spontaneously Blinking Janelia Fluor® Dyes allow facile single-molecule localization microscopy (SMLM) in cells and dense biomolecular structures, without the need for photoactivation or redox buffers. These spontaneously blinking dyes harness Janelia Fluor® technology to delivery dyes that automatically cycle between 'off' and 'on' states with an ideal duty cycle for super resolution microscopy experiments.

Key Information: Janelia Fluor® 646b, Maleimide is a spontaneously blinking fluorescent dye, supplied with a maleimide reactive group for conjugation (thiol reactivity) for the labeling of protein. Suitable to characterize the physical properties of dense biomolecule condensates and complex macromolecular assemblies.

Application: suitable for super resolution microscopy (SRM) including single-molecule localization microscopy (SMLM).

Properties and Photophysical Data: derived from Janelia Fluor® 646, Maleimide (Cat. No. 6590). Excitation and emission maxima (λ) are 662 nm and 674 nm, respectively.

Janelia Fluor is a registered trademark of Howard Hughes Medical Institute.

Optical Data for Janelia Fluor® 646b, Maleimide

Janelia Fluor<sup>®</sup> 646b, Maleimide Dye Spectra
λabs 662 nm
λem 674 nm

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Technical Data

M.Wt:
604.78
Formula:
C35H36N4O4Si
Purity:
≥90%
Storage:
Store at -20°C
CAS No:
2634129-70-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus

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