Human TGF-beta RII PE-conjugated Antibody Summary
Ile24-Asp159
Accession # P37173.2
Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Scientific Data
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Detection of TGF-beta RII in NS0 Mouse Cell Line transfected with TGF-beta RII by Flow Cytometry. NS0 mouse myeloma cell line transfected with TGF-beta RII was stained with Mouse Anti-Human TGF-beta RII PE-conjugated Monoclonal Antibody (Catalog # FAB241P, filled histogram) or isotype control antibody (Catalog # IC002P, open histo-gram). View our protocol for Staining Membrane-associated Proteins.
Preparation and Storage
- 12 months from date of receipt, 2 to 8 °C as supplied.
Background: TGF-beta RII
TGF-beta RII is a membrane bound serine/threonine kinase. Upon ligand binding, TGF-beta RII interacts with TGF-beta RI to form the heteromeric signaling complex that transduces TGF-beta signals. A splice variant of the type II receptor, TGF-beta RIIb, containing a 25 amino acid residue insertion near the N-terminus of the mature protein has also been described.
Product Datasheets
Citations for Human TGF-beta RII PE-conjugated Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
9
Citations: Showing 1 - 9
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Feline glycoprotein A repetitions predominant anchors transforming growth factor beta on the surface of activated CD4(+)CD25(+) regulatory T cells and mediates AIDS lentivirus-induced T cell immunodeficiency
Authors: Michelle M. Miller, Jonathan E. Fogle, Peter Ross, Mary B. Tompkins
AIDS Research and Human Retroviruses
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High Glucose Increases Lactate and Induces the Transforming Growth Factor Beta-Smad 1/5 Atherogenic Pathway in Primary Human Macrophages
Authors: Awad, K;Kakkola, L;Julkunen, I;
Biomedicines
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Dupuytren's Disease Is Mediated by Insufficient TGF-?1 Release and Degradation
Authors: Oezel, L;Wohltmann, M;Gondorf, N;Wille, J;Güven, I;Windolf, J;Thelen, S;Jaekel, C;Grotheer, V;
International journal of molecular sciences
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Quiescent innate and adaptive immune responses maintain the long-term integrity of corneal endothelium reconstituted through allogeneic cell injection therapy
Authors: M Toda, M Ueno, J Yamada, A Hiraga, K Asada, J Hamuro, C Sotozono, S Kinoshita
Scientific Reports, 2022-10-27;12(1):18072.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Reparative effect of mesenchymal stromal cells on endothelial cells after hypoxic and inflammatory injury
Authors: JM Sierra-Par, A Merino, M Eijken, H Leuvenink, R Ploeg, BK Møller, B Jespersen, CC Baan, MJ Hoogduijn
Stem Cell Res Ther, 2020-08-12;11(1):352.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry, Immunophenotyping -
Growth Factor-like Gene Regulation Is Separable from Survival and Maturation in Antibody-Secreting Cells
Authors: S Stephenson, MA Care, I Fan, A Zougman, DR Westhead, GM Doody, RM Tooze
J. Immunol., 2019-01-14;202(4):1287-1300.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
CD4+CD25+ T regulatory cells activated during feline immunodeficiency virus infection convert T helper cells into functional suppressors through a membrane-bound TGFbeta / GARP-mediated mechanism.
Authors: Miller M, Petty C, Tompkins M, Fogle J
Virol J, 2014-01-18;11(0):7.
Species: Feline
Sample Types: Whole Cells
Applications: Flow Cytometry -
Functional regulatory T cells accumulate in aged hosts and promote chronic infectious disease reactivation.
Authors: Lages CS, Suffia I, Velilla PA, Huang B, Warshaw G, Hildeman DA, Belkaid Y, Chougnet C
J. Immunol., 2008-08-01;181(3):1835-48.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Chronic exposure to asbestos enhances TGF-beta 1 production in the human adult T cell leukemia virus-immortalized T cell line MT-2
Authors: MEGUMI MAEDA, YING CHEN, HIROAKI HAYASHI, NAOKO KUMAGAI-TAKEI, HIDENORI MATSUZAKI, SUNI LEE et al.
International Journal of Oncology
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