Human SOX17 Antibody Summary
Asp177-Val414
Accession # Q9H6I2
Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Scientific Data
![SOX17 antibody in B16 Mouse Cell Line by Immunocytochemistry (ICC). SOX17 antibody in B16 Mouse Cell Line by Immunocytochemistry (ICC).](https://resources.rndsystems.com/images/datasheets/antibody/SOX17_MAB1924_Immunocytochemistry_10046.jpg)
SOX17 in B16 Mouse Cell Line. SOX17 was detected in immersion fixed B16 mouse melanoma cell line using Mouse Anti-Human SOX17 Monoclonal Antibody (Catalog # MAB1924) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Mouse IgG Secondary Antibody (yellow, upper panel; Catalog # NL007) and counterstained with DAPI (blue, lower panel). View our protocol for Fluorescent ICC Staining of Cells on Coverslips.
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: SOX17
SOX17 is a member of the SOX family of transcription factors that bind DNA via a high mobility group (HMG) domain. SOX17 is suggested to play an important role in endoderm development (1, 2).
- Kanai-Azuma, M. et al. (2002) Development 129:2367.
- Katoh, M. et al. (2002) Int. J. Mol. Med. 9:153.
Product Datasheets
Citations for Human SOX17 Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Citations: Showing 1 - 10
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Interplay of Oct4 with Sox2 and Sox17: a molecular switch from stem cell pluripotency to specifying a cardiac fate
Authors: Sonia Stefanovic, Nesrine Abboud, Stéphanie Désilets, David Nury, Chad Cowan, Michel Pucéat
Journal of Cell Biology
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Differentiation of immortalized human multi-lineage progenitor to alveolar type 2-like cells: angiotensin-converting enzyme 2 expression and binding of severe acute respiratory syndrome coronavirus 2 spike and spike 1 proteins
Authors: Collins DP, Osborn MJ, Steer CJ. et al.
Cytotherapy
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Generation and characterization of integration-free induced pluripotent stem cells from patients with autoimmune disease
Authors: Mi-Young Son, Mi-Ok Lee, Hyejin Jeon, Binna Seol, Jung Hwa Kim, Jae-Suk Chang et al.
Experimental & Molecular Medicine
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Transplantation of Human Embryonic Stem Cell-Derived Pancreatic Endoderm Reveals a Site-Specific Survival, Growth, and Differentiation
Authors: Lina Sui, Josué K. Mfopou, Bing Chen, Karen Sermon, Luc Bouwens
Cell Transplantation
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Transcriptomic analysis of feeder-free culture system for maintaining naïve-state pluripotency in human pluripotent stem cells
Authors: Wataru Isono, Tomoyuki Kawasaki, Justin K. Ichida, Kazunori Nagasaka, Osamu Hiraike, Akihiro Umezawa et al.
Stem Cell Investigation
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In Vitro Modeling of Alcohol-Induced Liver Injury Using Human-Induced Pluripotent Stem Cells
Authors: Lipeng Tian, Neha Prasad, Yoon-Young Jang
Methods in Molecular Biology
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Indolactam V/GLP-1-mediated differentiation of human iPS cells into glucose-responsive insulin-secreting progeny
Authors: Tayaramma Thatava, Timothy J. Nelson, Ramakrishna Edukulla, Toshie Sakuma, Seiga Ohmine, Jason M. Tonne et al.
Gene Therapy
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Depolymerizing F-actin accelerates the exit from pluripotency to enhance stem cell-derived islet differentiation
Authors: Hogrebe, NJ;Schmidt, MD;Augsornworawat, P;Gale, SE;Shunkarova, M;Millman, JR;
bioRxiv : the preprint server for biology
Species: Human
Sample Types: Whole Cells
Applications: Immunocytochemistry -
Generation of a gene-corrected human isogenic iPSC line from an Alzheimer's disease iPSC line carrying the PSEN1 H163R mutation
Authors: Hernández, D;Morgan Schlicht, S;Elli Clarke, J;Daniszewski, M;Karch, CM;Dominantly Inherited Alzheimer Network (DIAN), ;Goate, AM;Pébay, A;
Stem cell research
Species: Human
Sample Types: Whole Cells
Applications: Immunocytochemistry -
Generation of induced pluripotent stem cell lines IRMBi003-A and IRMBi003-B from a healthy donor to model Alzheimer's disease
Authors: Clua Provost, C;Auboyer, L;Rovelet-Lecrux, A;Monzo, C;Schob, E;Andreux, F;Quittet, C;Lehmann, S;Wallon, D;Crozet, C;
Stem cell research
Species: Human
Sample Types: Whole Cells
Applications: Immunocytochemistry/ Immunofluorescence -
Establishment of induced pluripotent stem cells IRMBi005-A from a patient with sporadic Alzheimer's disease
Authors: Provost, CC;Auboyer, L;Rovelet-Lecrux, A;Monzo, C;Schob, E;Lehmann, S;Wallon, D;Crozet, C;
Stem cell research
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of an induced pluripotent stem cell line XJHi001-A from a fibronectin glomerulopathy patient carrying a heterozygous NM_212482.2(C.5888-1G > C) mutation in the FN1 gene
Authors: She, L;Li, X;Bai, M;
Stem cell research
Species: Human
Sample Types: Transfected Whole Cells
Applications: ICC -
Large-scale production of human blastoids amenable to modeling blastocyst development and maternal-fetal cross talk
Authors: Yu, L;Logsdon, D;Pinzon-Arteaga, CA;Duan, J;Ezashi, T;Wei, Y;Ribeiro Orsi, AE;Oura, S;Liu, L;Wang, L;Liu, K;Ding, X;Zhan, L;Zhang, J;Nahar, A;Stobbe, C;Katz-Jaffe, M;Schoolcraft, WB;Tan, T;Hon, GC;Yuan, Y;Wu, J;
Cell stem cell
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of an induced pluripotent stem cell line (ZSZOCi001-A) from a patient with Knobloch syndrome caused by biallelic mutations in the gene COL18A1
Authors: Jiang, Z;Sun, W;Zhang, Q;Wang, P;
Stem cell research
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of a human fibroblast-derived induced pluripotent stem cell line KRIBBi009-A from a patient with breast cancer
Authors: N Son, YS Son, CR Jung, MY Son
Stem Cell Research, 2023-03-14;68(0):103060.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry, ICC -
Efficient reprogramming of human fibroblasts using RNA reprogramming with DAPT and iDOT1L under normoxia conditions
Authors: K Morita, A Nakamura, M Machida, T Kawasaki, R Nakanishi, J Ichida, T Iwata, A Umezawa, H Akutsu
Regenerative Therapy, 2022-09-19;21(0):389-397.
Species: Human
Sample Types: Organoid
Applications: IHC -
Generation of a human induced pluripotent stem cell line (LZUSHi002-A) from a MADD patient with ETFDH mutation
Authors: Y Li, Y Li, H Liu, L Cheng, H Ma, X Xu, N Zhang
Stem Cell Research, 2022-09-14;64(0):102914.
Species: Human
Sample Types: Whole Cells
Applications: IHC -
Generation of a homozygous knock-in human embryonic stem cell line expressing mEos4b-tagged CTR1
Authors: YH Chen, PS Huang, MH Wen, M Pan, DF Lee, TY Chen
Oncogene, 2022-06-14;63(0):102845.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of an integration-free induced pluripotent stem cell line (LZUSHI001-A) from an epileptic patient with DGKG mutation
Authors: YQ Liu, TW Ling, HY Wang, YH Yang, WJ Song, TC Wang
Stem Cell Research, 2022-03-28;61(0):102768.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of a gene corrected human isogenic iPSC line (CPGHi001-A-1) from a hearing loss patient with the TMC1 p.M418K mutation using CRISPR/Cas9
Authors: H Wang, Y Luo, J Li, J Guan, S Yang, Q Wang
Stem Cell Research, 2022-02-28;60(0):102736.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of an induced pluripotent stem cell line (FDCHI007-A) derived from a patient with developmental and epileptic encephalopathy Type 31 carrying heterozygous c.545C�>�A mutation in DNM1 gene
Authors: Y Xu, X Wang, T Qiu, J Wang, Y Wang, B Wu, Y Zhou
Stem Cell Research, 2022-02-12;60(0):102709.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
SOX17 and PAX8 constitute an actionable lineage-survival transcriptional complex in ovarian cancer
Authors: L Lin, K Shi, S Zhou, MC Cai, C Zhang, Y Sun, J Zang, L Cheng, K Ye, P Ma, P Shen, M Zhang, Y Cheng, C Qi, Y Li, X Yin, Y Zheng, L Tan, G Zhuang, R Zang
Oncogene, 2022-02-05;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of human induced pluripotent stem cell line, KRIBBi003-A, from urinary cells of a patient with glycogen storage disease type IXa
Authors: Y Shin, SJ Mun, J Lee, KS Chung, M Kim, C Kun Cheon, MJ Son
Stem Cell Research, 2021-10-22;57(0):102584.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry, ICC -
Generation of an induced pluripotent stem cell line (FDCHi006-A) from a 7-year-old girl with central precocious puberty
Authors: T Fan, J He, Y Wang, J Yu, W Sun
Stem Cell Research, 2021-09-28;56(0):102542.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry, ICC -
Generation of insulin-producing pancreatic beta cells from multiple human stem cell lines
Authors: NJ Hogrebe, KG Maxwell, P Augsornwor, JR Millman
Nature Protocols, 2021-08-04;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry, ICC -
Generation of human induced pluripotent stem cell lines from 2 patients with MIRAGE syndrome
Authors: I Fischer, J Küchler, C Schaar, T Fisch, J Cernoch, K Fischer, V Fernández, P Kühnen, H Stachelsch
Stem Cell Research, 2021-06-10;54(0):102417.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Generation of an iPSC line (GWCMCi002-A) from an X-linked Alport syndrome patient with a hemizygous splicing mutation (NM_000495.4, c. 1517-1 G�>�T) in the COL4A5 gene
Authors: X Gao, G Li, H Deng, W Feng, Y Li, M Liu, Y Li
Stem Cell Research, 2021-05-11;53(0):102388.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of a human induced pluripotent stem cell line (CPGHi003-A) from an auditory neuropathy patient with AIFM1 p.R422Q mutation
Authors: J Li, K Wu, J Guan, Q Wang, H Wang
Stem Cell Research, 2021-04-29;53(0):102376.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Generation of an induced pluripotent stem cell line (OGHFUi001-A) from a type 1 early infantile epileptic encephalopathy with ARX mutation
Authors: N Jia, X Gong, J Chen, T Yang, C Bao, J Shen, X Xiao
Stem Cell Research, 2021-04-27;53(0):102367.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
An induced pluripotent stem cell line (GZHMCi004-A) derived from a fetus with heterozygous G380R mutation in FGFR3 gene causing achondroplasia
Authors: N Li, SM Lin, Y Li, J Sun, L Zhang, M Chen
Stem Cell Research, 2021-04-05;53(0):102322.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry, ICC -
Generation of a gene corrected human isogenic iPSC line (CPGHi002-A-1) from a DDOD patient with heterozygous c.1516 C>T mutation in the ATP6V1B2 gene
Authors: X Gao, SW Qiu, WQ Wang, DY Kang, N Su, P Dai, YY Yuan
Stem Cell Research, 2021-02-25;53(0):102271.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Generation of a gene-corrected isogenic iPSC line (AHQUi001-A-1) from a patient with familial hypertriglyceridemia (FHTG) carrying a heterozygous p.C310R (c.928�T�>�C) mutation in LPL gene using CRISPR/Cas9
Authors: X Sun, X Zhou, B Dong, C Wang, X Xiao, Y Wang
Stem Cell Research, 2021-02-11;52(0):102230.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry, ICC -
An induced pluripotent stem cell line (GZHMCi003-A) derived from a fetus with exon 3 heterozygous deletion in RUNX2 gene causing cleidocranial dysplasia
Authors: M Chen, SM Lin, N Li, Y Li, Y Li, L Zhang
Stem Cell Research, 2021-01-09;51(0):102166.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry, ICC -
Derivation of an induced pluripotent stem cell line (GWCMCi001-A) from PBMCs of a four-year-old male patient with Immunoglobulin A nephropathy
Authors: X Gao, X Liao, J Zhang, J Lin, M Tan
Stem Cell Research, 2020-12-10;50(0):102123.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Generation of an induced pluripotent stem cell line (PUMCHi006-A) derived from a patient with pulmonary arterial hypertension carrying heterozygous c.1339 G�>�A mutation in PTGIS gene
Authors: YJ Zhu, SJ Zhang, XH Wu, TY Lian, YZ He, ZJ Zhang, D Lu, K Sun, HF Wang, ZC Jing
Stem Cell Res, 2020-11-15;49(0):102088.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of gene-corrected iPSCs line (KEIUi001-A) from a PARK8 patient iPSCs with familial Parkinson's disease carrying the I2020T mutation in LRRK2
Authors: E Ohta, T Sone, H Ukai, T Hisamatsu, T Kitagawa, M Ishikawa, M Nagai, HR Ueda, F Obata, H Okano
Stem Cell Res, 2020-11-03;49(0):102073.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Establishment of human induced pluripotent stem cell line (CPGHi002-A) from a 10-month-old female patient with DDOD syndrome carrying a heterozygous c.1516 C�>�T mutation in ATP6V1B2
Authors: X Gao, SW Qiu, ML Feng, SS Huang, DY Kang, MY Han, P Dai, YY Yuan
Stem Cell Res, 2020-09-08;48(0):101986.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
The combination of dibenzazepine and a DOT1L inhibitor enables a stable maintenance of human na�ve-state pluripotency in non-hypoxic conditions
Authors: W Isono, T Kawasaki, JK Ichida, T Ayabe, O Hiraike, A Umezawa, H Akutsu
Regenerative Therapy, 2020-09-02;15(0):161-168.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of an induced pluripotent stem cell line (CHFUi001-A) from an osteogenesis imperfecta patient with COL1A2 mutation
Authors: Z Zheng, W Lu, Z Pei, J Chen, T Yang, F Luo
Stem Cell Res, 2020-07-05;47(0):101907.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
An induced pluripotent stem cell line (SHEHi002-A (5426))from a patient of long QT syndrome type 8 with c.2573G>A mutation in the gene CACNA1C
Authors: HM Zhou, XQ Zhou, JZ Lu, WW Jia, JH Kang
Stem Cell Res, 2020-02-06;43(0):101731.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Measles vector as a multiple genes delivery platform facilitating iPSC reprogramming
Authors: Q Wang, A Vossen, Y Ikeda, P Devaux
Gene Ther., 2019-02-04;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of two human isogenic iPSC lines from fetal dermal fibroblasts
Authors: R Tandon, B Brändl, N Baryshniko, A Landshamme, L Steenpa beta, O Keminer, O Pless, FJ Müller
Stem Cell Res, 2018-10-12;33(0):120-124.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Low Cell-Matrix Adhesion Reveals Two Subtypes of Human Pluripotent Stem Cells
Authors: L Yu, J Li, J Hong, Y Takashima, N Fujimoto, M Nakajima, A Yamamoto, X Dong, Y Dang, Y Hou, W Yang, I Minami, K Okita, M Tanaka, C Luo, F Tang, Y Chen, C Tang, H Kotera, L Liu
Stem Cell Reports, 2018-06-28;11(1):142-156.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of an induced pluripotent stem cell line from a patient with adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP): HIHCNi003-A
Authors: SN Hayer, Y Schelling, P Hoeflinger, S Hauser, L Schöls
Stem Cell Res, 2018-06-20;30(0):206-209.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
PI3K/mTORC2 regulates TGF-beta/Activin signalling by modulating Smad2/3 activity via linker phosphorylation.
Authors: Yu J, Ramasamy T, Murphy N, Holt M, Czapiewski R, Wei S, Cui W
Nat Commun, 2015-05-22;6(0):7212.
Species: Human
Sample Types: Cell Lysates, Whole Cells
Applications: IHC, Western Blot -
Intrapatient variations in type 1 diabetes-specific iPS cell differentiation into insulin-producing cells.
Authors: Thatava T, Kudva Y, Edukulla R, Squillace K, De Lamo J, Khan Y, Sakuma T, Ohmine S, Terzic A, Ikeda Y
Mol Ther, 2012-11-27;21(1):228-39.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry, IHC-Fr -
FGF signaling via MAPK is required early and improves Activin A-induced definitive endoderm formation from human embryonic stem cells.
Authors: Sui L, Mfopou J, Geens M, Sermon K, Bouwens L
Biochem Biophys Res Commun, 2012-08-29;426(3):380-5.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
New cell lines from mouse epiblast share defining features with human embryonic stem cells.
Authors: Tesar PJ, Chenoweth JG, Brook FA, Davies TJ, Evans EP, Mack DL, Gardner RL, McKay RD
Nature, 2007-06-27;448(7150):196-9.
Species: Mouse
Sample Types: Whole Cells
Applications: ICC -
Conditional gene expression in human embryonic stem cells.
Authors: Vallier L, Alexander M, Pedersen R
Stem Cells, 2007-02-22;25(6):1490-7.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Neurogenic effect of vascular endothelial growth factor during germ layer formation of human embryonic stem cells.
Authors: Kim BK, Kim SE, Shim JH, Woo DH, Gil JE, Kim SK, Kim JH
FEBS Lett., 2006-10-02;580(25):5869-74.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Reprogrammed keratinocytes from elderly type 2 diabetes patients suppress senescence genes to acquire induced pluripotency
Authors: Seiga Ohmine, Karen A. Squillace, Katherine A. Hartjes, Michael C. Deeds, Adam S. Armstrong, Tayaramma Thatava et al.
Aging (Albany NY)
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Hepatic Differentiation of Marmoset Embryonic Stem Cells and Functional Characterization of ESC-Derived Hepatocyte-Like Cells
Authors: Rajagopal N Aravalli, Daniel P Collins, Joel H Hapke, Andrew T Crane, Clifford J Steer
Hepatic Medicine: Evidence and Research
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Engineering human hepato-biliary-pancreatic organoids from pluripotent stem cells
Authors: Hiroyuki Koike, Kentaro Iwasawa, Rie Ouchi, Mari Maezawa, Masaki Kimura, Asuka Kodaka et al.
Nature Protocols
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Induced pluripotent stem cells from GMP-grade hematopoietic progenitor cells and mononuclear myeloid cells
Authors: Seiga Ohmine, Allan B Dietz, Michael C Deeds, Katherine A Hartjes, David R Miller, Tayaramma Thatava et al.
Stem Cell Research & Therapy
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Effects of the Extracts from Fruit and Stem of Camellia japonica on Induced Pluripotency and Wound Healing
Authors: H Jeon, JY Kim, JK Choi, E Han, CL Song, J Lee, YS Cho
J Clin Med, 2018-11-20;7(11):.
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Changes in the hepatic differentiation potential of human mesenchymal stem cells aged in vitro
Authors: Sang Luo, Shuai Xiao, Yang Ai, Ben Wang, Yefu Wang
Annals of Translational Medicine
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Early gestation chorionic villi-derived stromal cells for fetal tissue engineering
Authors: Lee Lankford, Taryn Selby, James Becker, Volodymyr Ryzhuk, Connor Long, Diana Farmer et al.
World Journal of Stem Cells
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Intrinsic Immunity Shapes Viral Resistance of Stem Cells
Authors: Xianfang Wu, Viet Loan Dao Dao Thi, Yumin Huang, Eva Billerbeck, Debjani Saha, Hans-Heinrich Hoffmann et al.
Cell
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