Human/Rat Lyn Alexa Fluor® 750-conjugated Antibody

Catalog #: FAB3206S Datasheet

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FAB3206S-100UG

All Lyn Antibodies

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Human/Rat Lyn Alexa Fluor® 750-conjugated Antibody Summary

Species Reactivity

Human, Rat

Specificity

Detects human and rat Lyn.

Source

Monoclonal Mouse IgG2b Clone # 338716

Purification

Protein A or G purified

Immunogen

E. coli-derived recombinant human Lyn
Met1-Ile67
Accession # P07948

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 750 (Excitation= 749 nm, Emission= 775 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Immunocytochemistry

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: Lyn

The nonreceptor tyrosine kinase Lyn (lck/yes-related novel tyrosine kinase) is widely expressed, and the predominant Src family member present in B cells. Activation of Lyn occurs upon its association with cell surface receptors such as BCR and CD40. Analyses from both loss- and gain-of-function mutant mice have revealed that Lyn is an essential regulator of B cell activation, maturation, and tolerance.

Long Name

V-Yes-1 Yamaguchi Sarcoma Viral Related Oncogene Homolog

Entrez Gene IDs

4067 (Human); 17096 (Mouse); 81515 (Rat)

Alternate Names

EC 2.7.10; EC 2.7.10.2; FLJ26625; Hck-2; JTK8; Lyn; tyrosine-protein kinase Lyn; v-yes-1 Yamaguchi sarcoma viral related oncogene homolog; v-yes-1; Yamaguchi sarcoma viral (v-yes-1) related oncogene homolog

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FAQs

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