Home / PP1 alpha / Human PP1 alpha Catalytic Subunit Alexa Fluor® 750-conjugated Antibody

Human PP1 alpha Catalytic Subunit Alexa Fluor® 750-conjugated Antibody

Catalog #: FAB6105S Datasheet
Catalog # Availability Size / Price Qty
FAB6105S-100UG
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Human PP1 alpha Catalytic Subunit Alexa Fluor® 750-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects human PP1 alpha Catalytic Subunit in Western blots. In Western blots, no cross-reactivity with recombinant human (rh) PP1 beta or rhPP1 gamma is observed.
Source
Monoclonal Mouse IgG2a Clone # 490314
Purification
Protein A or G purified
Immunogen
synthetic peptide corresponding to Gly304-Arg317 of human PP1α catalytic subunit

Gly304-Arg317
Accession # P62136
Formulation
Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide
Label
Alexa Fluor 750 (Excitation= 749 nm, Emission= 775 nm)

Applications

Recommended Concentration
Sample
Western Blot
Optimal dilution of this antibody should be experimentally determined.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: PP1 alpha

Protein Phosphatase 1, also known as PP1 and PPP1, is an enzyme that removes phosphate groups attached to serine or threonine residues in proteins. The holoenzyme is composed of two subunits, a catalytic subunit that is highly conserved throughout evolution, and a wide variety of regulatory subunits that target the enzyme to specific subcellular compartments and proteins. Three isoforms of the catalytic subunit are ubiquitously expressed in tissues and cell lines: PP1 alpha, PP1 beta and PP1 gamma.

Long Name
Protein Phosphatase 1 Catalytic Subunit alpha
Entrez Gene IDs
5499 (Human); 19045 (Mouse); 24668 (Rat)
Alternate Names
EC 3.1.3.16; PP1 alpha; PP1alpha; PP-1AMGC15877; PPP1A; PPP1AMGC1674; PPP1CA; protein phosphatase 1, catalytic subunit, alpha isoform; protein phosphatase 1, catalytic subunit, alpha isozyme; serine/threonine protein phosphatase PP1-alpha 1 catalytic subunit; serine/threonine-protein phosphatase PP1-alpha catalytic subunit

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