Human Phospho-VEGFR1/Flt-1 (Y1213) Alexa Fluor® 647-conjugated Antibody

Applications

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Preparation and Storage

Background: VEGFR1/Flt-1

VEGFR1, also known as Flt-1, is a receptor tyrosine kinase that contains seven Ig-like repeats in its extracellular domain, a single transmembrane region, and a kinase domain in the intracellular region. Ligand binding induces autophosphorylation on multiple intracellular tyrosine residues. Y1213 is a major binding site for PI3K, Nck, and SHP-2.

Product Datasheets

Related Research Areas

• Airway Inflammation and Remodeling
• Cancer Biomarkers
• Cytokine and Growth Factor Receptors on VSMC
• Endothelial Cell Differentiation Markers
• Endothelial Cell Markers
• Endothelial Progenitor and Endothelial Cell Markers
• HIF Transcription Factors
• Microglia Development
• Myeloid-derived Suppressor Cells (MDSC)
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• Receptor Tyrosine Kinases (RTKs)
• Receptor Tyrosine Kinases (RTKs) in the Akt Pathway
• Receptors in the Jak/STAT Pathway
• VEGF Family
• VEGF Receptors and Regulators on Endothelial Cells