Human NRAMP1/SLC11A1 APC-conjugated Antibody

Catalog #: FAB8400A Datasheet

Catalog #	Availability	Size / Price	Qty
FAB8400A-025

Detection of NRAMP1/SLC11A1 in HEK293 Human Cell Line Transfected with Human NRAMP1/SLC11A1 and eGFP by Flow Cytometry.

1 Image

All NRAMP1/SLC11A1 Antibodies

Product Details

FAQs

Supplemental Products

Reviews

Summary Data Examples Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human NRAMP1/SLC11A1 APC-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects HEK293 human embryonic kidney cell line transfected with human NRAMP1/SLC11A1 by Flow Cytometry. Does not detect untransfected or irrelevant transfected HEK293 cells.

Source

Monoclonal Mouse IgG_2B Clone # 910825

Purification

Protein A or G purified from hybridoma culture supernatant

Immunogen

NS0 mouse myeloma cell line transfected with human NRAMP1/SLC11A1
Met1-Gly550
Accession # NP_000569

Formulation

Supplied in a saline solution containing BSA and Sodium Azide.

Label

Allophycocyanin (Excitation= 620-650 nm, Emission= 660-670 nm)

Applications

Recommended Concentration

Sample

Flow Cytometry

10 µL/10⁶ cells

See below

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Flow Cytometry

View Larger

Detection of NRAMP1/SLC11A1 in HEK293 Human Cell Line Transfected with Human NRAMP1/SLC11A1 and eGFP by Flow Cytometry. HEK293 human embryonic kidney cell line transfected with (A) human NRAMP1/SLC11A1 or (B) irrelevant transfectants and eGFP was stained with Mouse Anti-Human NRAMP1/SLC11A1 APC-conjugated Monoclonal Antibody (Catalog # FAB8400A). Quadrant markers were set based on control antibody staining (Catalog # IC0041A). View our protocol for Staining Membrane-associated Proteins.

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze.

12 months from date of receipt, 2 to 8 °C as supplied.

Background: NRAMP1/SLC11A1

NRAMP1/SLC11A1 (Natural Resistance-Associated Macrophage Protein 1/Solute Carrier family 11, member 1) is a member of the solute carrier family of multi-pass membrane proteins. It functions as a proton-coupled divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Mutations in SLC11A1 have been associated with susceptibility to infectious diseases such as tuberculosis and leprosy, and inflammatory diseases such as rheumatoid arthritis and Crohn’s disease. Alternatively spliced variants that encode different protein isoforms have been described.

Long Name

Natural Resistance-associated Macrophage Protein 1

Entrez Gene IDs

6556 (Human); 18173 (Mouse); 316519 (Rat)

Alternate Names

natural resistance-associated macrophage protein 1; LSH; member 1; NRAMP 1; NRAMP1; NRAMP1solute carrier family 11 (sodium/phosphate symporters), member 1; NRAMPnatural resistance-associated macrophage protein 1; SLC11A1; solute carrier family 11 (proton-coupled divalent metal ion transporters)

Product Datasheets

Product Datasheet

Related Research Areas

Solute Carrier Family (SLC)

FAQs

No product specific FAQs exist for this product, however you may

View all Antibody FAQs

Reviews for Human NRAMP1/SLC11A1 APC-conjugated Antibody

There are currently no reviews for this product. Be the first to review Human NRAMP1/SLC11A1 APC-conjugated Antibody and earn rewards!

Have you used Human NRAMP1/SLC11A1 APC-conjugated Antibody?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review