Human Nectin-4 Alexa Fluor® 647-conjugated Antibody

Applications

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Preparation and Storage

Background: Nectin-4

Nectin-4 is a type I transmembrane glycoprotein belonging to the Nectin family of Ig superfamily proteins. It is both a homophilic and heterophilic (with Nectin-1) cell adhesion molecule that is expressed in the embryo and in breast carcinoma. A soluble form of Nectin-4 is generated from the membrane protein via the action of TACE/ADAM-17. The extracellular domain of human Nectin-4 shares 90% and 92% amino acid sequence homology with the corresponding regions of mouse and rat Nectin-4, respectively.

Product Datasheets

Related Research Areas

• Cell to Cell Adhesion Disassembly During EMT
• Epithelial Cell Markers and Intracellular Molecules
• Epithelial Cell Polarity
• Infectious Diseases
• Nectin and Nectin-like Binding Receptors and Ligands
• Nectins
• Search Immune Checkpoint Targets
• Surface Ectodermal Cells