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Human/Mouse/Rat SOX2 Antibody

Catalog #: AF2018
369 Citations 7 Reviews Datasheet
Catalog # Availability Size / Price Qty
AF2018
AF2018-SP
Detection of Human, Mouse, and Rat SOX2 by Western Blot.
19 Images
Product Details
Citations (369)
FAQs
Supplemental Products
Reviews (7)
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Human/Mouse/Rat SOX2 Antibody Summary

Species Reactivity
Human, Mouse, Rat
Specificity
Detects human SOX2 in direct ELISAs and Western blots.
Source
Polyclonal Goat IgG
Purification
Antigen Affinity-purified
Immunogen
E. coli-derived recombinant human SOX2
Gly135-Met317
Accession # P48431
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Label
Unconjugated

Applications

Recommended Concentration
Sample
Western Blot
1 µg/mL
See below
Simple Western
5 µg/mL
See below
Immunohistochemistry
3-25 µg/mL
Immersion fixed paraffin-embedded sections of glioblastoma
Chromatin Immunoprecipitation (ChIP)
5 µg/5 x 106 cells
See below
Immunocytochemistry
5-15 µg/mL
Immersion fixed NTera-2 human testicular embryonic carcinoma cell line, BG01V human embryonic stem cells cultured on irradiated mouse embryonic fibroblasts, undifferentiated mouse cortical stem cells, undifferentiated rat cortical stem cells, ADLF1 and FAB2 induced pluripotent stem cell lines, and HepG2 human hepatocellular carcinoma cells

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Western Blot Detection of Human, Mouse, and Rat SOX2 antibody by Western Blot. View Larger

Detection of Human, Mouse, and Rat SOX2 by Western Blot. Western blot shows lysates of D3 mouse embryonic stem cell line, NTera-2 human testicular embryonic carcinoma cell line, F9 mouse teratocarcinoma stem cells, and rat cortical stem cells. PVDF membrane was probed with 1 µg/mL of Goat Anti-Human/Mouse/Rat SOX2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2018) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (HAF017). A specific band was detected for SOX2 at approximately 36 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

Chromatin Immunoprecipitation (ChIP) Detection of SOX2-regulated Genes antibody by Chromatin Immunoprecipitation. View Larger

Detection of SOX2-regulated Genes by Chromatin Immunoprecipitation. BG01V human embryonic stem cells were fixed using formaldehyde, resuspended in lysis buffer, and sonicated to shear chromatin. SOX2/DNA complexes were immunoprecipitated using 5 µg Goat Anti-Human/Mouse/Rat SOX2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2018) or control antibody (AB-108-C) for 15 minutes in an ultrasonic bath, followed by Biotinylated Anti-Goat IgG Secondary Antibody (BAF109). Immunocomplexes were captured using 50 µL of MagCellect Streptavidin Ferrofluid (MAG999) and DNA was purified using chelating resin solution. Thenanogpromoter was detected by standard PCR.

Immunocytochemistry SOX2 antibody in Mouse Cortical Stem Cells by Immunocytochemistry (ICC). View Larger

SOX2 in Mouse Cortical Stem Cells. SOX2 was detected in immersion fixed undifferentiated mouse cortical stem cells using Goat Anti-Human/Mouse/Rat SOX2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2018) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red; (NL001) and counterstained with DAPI (blue). Nestin was also detected in stem cells using Mouse Anti-Mouse/Rat Nestin Monoclonal Antibody (MAB2736) and co-stained using the NorthernLights™ 493-conjugated Anti-Mouse IgG Secondary Antibody (green; NL009). Specific staining of SOX2 was localized to nuclei. View our protocol for Fluorescent ICC Staining of Stem Cells on Coverslips.

Immunocytochemistry SOX2 antibody in Rat Cortical Stem Cells by Immunocytochemistry (ICC). View Larger

SOX2 in Rat Cortical Stem Cells. SOX2 was detected in immersion fixed undifferentiated rat cortical stem cells using Goat Anti-Human/Mouse/Rat SOX2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2018) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red; NL001) and counterstained with DAPI (blue). Nestin was also detected using Mouse Anti-Mouse/Rat Nestin Monoclonal Antibody (MAB2736) and stained using the NorthernLights™ 493-conjugated Anti-Mouse IgG Secondary Antibody (green; NL009). Specific staining of SOX2 was localized to nuclei. View our protocol for Fluorescent ICC Staining of Stem Cells on Coverslips.

Simple Western Detection of Human SOX2 antibody by Simple Western<sup>TM</sup>. View Larger

Detection of Human SOX2 by Simple WesternTM. Simple Western lane view shows lysates of BG01V human embryonic stem cells and NTera-2 human testicular embryonic carcinoma cell line, loaded at 0.2 mg/mL. A specific band was detected for SOX2 at approximately 53 kDa (as indicated) using 5 µg/mL of Goat Anti-Human/Mouse/Rat SOX2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2018) followed by 1:50 dilution of HRP-conjugated Anti-Goat IgG Secondary Antibody (HAF109). This experiment was conducted under reducing conditions and using the 12-230 kDa separation system.

Immunocytochemistry SOX2 antibody in ADLF1 and FAB2 Stem Cell Lines by Immunocytochemistry (ICC). View Larger

SOX2 in ADLF1 and FAB2 Stem Cell Lines. SOX2 was detected in immersion fixed ADLF1 (top panel) and FAB2 (bottom panel) induced pluripotent stem cell lines using Goat Anti-Human/Mouse/Rat SOX2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2018) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red; NL001) and counterstained with DAPI (blue). Specific staining was localized to nuclei. View our protocol for Fluorescent ICC Staining of Stem Cells on Coverslips.

Immunohistochemistry View Larger

Detection of SOX2 in glioblastoma. SOX2 was detected in immersion fixed paraffin-embedded sections of glioblastoma using Goat Anti-Human/Mouse/Rat SOX2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2018) at 3 µg/mL for 1 hour at room temperature followed by incubation with the Anti-Goat IgG VisUCyte™ HRP Polymer Antibody (Catalog # VC004). Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using VisUCyte Antigen Retrieval Reagent-Basic (Catalog # VCTS021). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to nuclei in cancer cells. View our protocol for IHC Staining with VisUCyte HRP Polymer Detection Reagents.

Immunocytochemistry View Larger

Detection of SOX2 in NTera‑2 cells (Positive) & HepG2 cells (Negative). SOX2 was detected in immersion fixed NTera‑2 human testicular embryonic carcinoma cells (Positive) & absent in HepG2 human hepatocellular carcinoma cells (Negative) using Goat Anti-Human/Mouse/Rat SOX2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2018) at 5 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red; Catalog # NL001) and counterstained with DAPI (blue). Specific staining was localized to Cell surface and nuclear. View our protocol for Fluorescent ICC Staining of Cells on Coverslips.

Western Blot Detection of Human SOX2 by Western Blot View Larger

Detection of Human SOX2 by Western Blot Knockdown OGT inhibits proliferation and tumorsphere formation of hepatoma cell through reducing eIF4E expression. A, Huh7 and PLC/PRF/5 cells were infected with control shRNA, OGT shRNA2 alone, or with wild‐type eIF4E lentivirus. The cell lysates were harvested for western blotting analysis using indicated antibodies. beta ‐actin expression was served as a loading control. B, Cell proliferation of Huh7 and PLC/PRF/5 cells infected with lentiviruses as in panel (A) were measured with CCK8 assay. (C‐H) Huh7 and PLC/PRF/5 cells infected with lentiviruses as in panel (A) were seeded into 96‐well plates. After 12 d, tumorsphere were counted and quantified. Representative images of sphere (scale bars, 100 μm) were shown (C, F). The diameter of sphere (D, G) and number of sphere (E, H) were count. Data represent mean ± SD of at least three independent experiments. The two‐tailed Student's t tests were used. **P < 0.01. I, Huh7 cells expressing either OGT shRNA2 alone or with wild‐type eIF4E lentivirus were incubated with PE‐labelled anti‐AC133 antibody. The percentages of CD133+ cells in graphs were analysed by flow cytometry. Black line, control IgG staining; red line, CD133 staining. J, Cell lysates were examined by western blotting with indicated antibodies. The right panel showcases relative protein amounts of different groups. Error bars represent ±SD of triplicate experiments. **P < 0.01; n.s, no significance. K, Huh7 cells were collected and subjected to immunoprecipitation with antibody against eIF4E or normal mouse IgG. Total RNAs were purified from immunocomplexes and subjected to RT‐PCR to measure Sox2, OCT4, and KLF4 mRNAs associated with eIF4E Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/30677218), licensed under a CC-BY license. Not internally tested by R&D Systems.

Immunohistochemistry Detection of Human SOX2 by Immunohistochemistry View Larger

Detection of Human SOX2 by Immunohistochemistry TP63 and SOX2 staining in cervical biopsies.Immunohistochemical staining of cervical biopsies. Bars  =  50µm.(A) normal cervix no primary control; (B) normal cervix stained with anti-SOX2; (C) Squamous cell cervical carcinoma no primary control; (D) representative TP63, and (E) representative SOX2, staining of tumour cells. For both TP63 and SOX2 staining was seen in the nucleus of positive cells (examples indicated by solid arrows); negative cells were a minority of tumour cells (examples indicated by unfilled arrows). (F) Image analysis results of % nuclear +ve tumour cells in biopsies. Parallel sections from 11 cases were stained with SOX2 and TP63. Tumour cells were evaluated for their nuclear expression of the transcription factors. There was no significant difference between the data for SOX2 and TP63 (Wilcoxon signed rank test). Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/25531390), licensed under a CC-BY license. Not internally tested by R&D Systems.

Immunohistochemistry Detection of Zebrafish SOX2 by Immunohistochemistry View Larger

Detection of Zebrafish SOX2 by Immunohistochemistry Direct effects of glucocorticoids in ependymal glia. (A–I) Zebrafish spinal cord transverse sections. (A–C) Immunostaining of wild-types for Nr3c1 (green) and Gfap (red), plus DAPI staining (blue) with Dex treatment at 24 h post sham injury (A), 24 h (B) and 48 h post SCI (C). Nuclear Nr3c1 (active) localization in Gfap-positive cells around the central canal is stimulated with Dex treatment. (D–F) Immunostaining for EGFP (pan-cytoplasmic) in the SR4G transgenic reporter line (green) and filamentous Gfap (red) at 24 h post sham injury (D) and SCI with no treatment (E) or 24 h post SCI +Dex (F). Nr3c1 signaling is constitutively active in ependymal glia in uninjured controls (D), diminished after SCI (E), and was maintained after SCI + Dex. (G–I) Immunostaining for Sox2 (green), PCNA (red) and Gfap (blue) from 48 h post sham injury (G), 48 h post SCI followed by no treatment (H), or 48 h post SCI +Dex (I). Sox2 immunoreactivity is reduced in ependymal glia and neural precursor cells after Dex treatment. Representative images from 10 spinal cords per time point in each condition. Scale bars, 20 μm (A is the same as B,C; D is the same as E,F; G is the same as H,I). ∗denotes central canal. Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/31069223), licensed under a CC-BY license. Not internally tested by R&D Systems.

Chromatin Immunoprecipitation Detection of Mouse SOX2 by Chromatin Immunoprecipitation View Larger

Detection of Mouse SOX2 by Chromatin Immunoprecipitation Epigenetic perturbation of enhancer clustering and genome-widebinding.(A) The fluctuation range (x) and amplitude (y) were obtainedby fitting the pair-correlation function of the indicated dataset with thefluctuation model. Figure 2 and Figure 2—figure supplement 1,Equations10–13. Supplementary file 1. Data from the same conditionwere grouped in separate ellipses. (B) Sox2 ChIP-exo peakdensity distribution in the wild-type and TSA treated (red dotted) cellsacross chromosome 1, 2, 3. In the upper panels, each chromosome was dividedto 500 bins. The color map correlates with the number of peaks in each bin.Top 7000 binding sites were considered in each condition. (C)Cumulative density histogram of the distances to transcription start sites(TSS's) of Sox2 ChIP-exo peaks in WT, Sox2 ChIP-exo peaks in the TSA treatedcells (red dotted), and random genomic positions (gray).DOI:https://dx.doi.org/10.7554/eLife.04236.013 Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/25537195), licensed under a CC-BY license. Not internally tested by R&D Systems.

Immunohistochemistry Detection of Human SOX2 by Immunohistochemistry View Larger

Detection of Human SOX2 by Immunohistochemistry TP63 and SOX2 staining in cervical biopsies.Immunohistochemical staining of cervical biopsies. Bars  =  50µm.(A) normal cervix no primary control; (B) normal cervix stained with anti-SOX2; (C) Squamous cell cervical carcinoma no primary control; (D) representative TP63, and (E) representative SOX2, staining of tumour cells. For both TP63 and SOX2 staining was seen in the nucleus of positive cells (examples indicated by solid arrows); negative cells were a minority of tumour cells (examples indicated by unfilled arrows). (F) Image analysis results of % nuclear +ve tumour cells in biopsies. Parallel sections from 11 cases were stained with SOX2 and TP63. Tumour cells were evaluated for their nuclear expression of the transcription factors. There was no significant difference between the data for SOX2 and TP63 (Wilcoxon signed rank test). Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/25531390), licensed under a CC-BY license. Not internally tested by R&D Systems.

Immunocytochemistry/ Immunofluorescence Detection of Human SOX2 by Immunocytochemistry/Immunofluorescence View Larger

Detection of Human SOX2 by Immunocytochemistry/Immunofluorescence Generation of KCNA5 knockout model. (A) Illustration of polycistronic self-replicating RNA used for reprogramming (Yoshioka et al., 2013). Reading frames for OCT4, KLF4, SOX2, GLIS1, and puromycin resistance are separated by 2A peptide-encoding or IRES sequences. (B) Phase contrast morphology (5 x) and alkaline phosphatase staining of the F1 wild-type hiPSC line generated using the RNA vector shown in (A). (C) Representative F1 karyogram indicating a normal male genotype. (D) The RNA vector is undetectable in established F1 hiPSCs following puromycin withdrawal, whereas freshly transfected parental fibroblasts display robust transgene expression (RT-qPCR data, n = 2). (E) Bisulfite sequencing of OCT4 and NANOG promoter regions of the indicated samples showing an hESC-like hypomethylated state in F1 cells. (F) RT-qPCR analysis of F1 hiPSCs in comparison to the original fibroblasts and a hESC control (n = 2). (G) Immunostains showing robust pluripotency factor expression in F1 hiPSCs at the protein level. (H) Illustration of the Kv1.5 channel. The voltage sensor in transmembrane helix S4 is indicated by symbols. The ion pore region is in-between segments S5 and S6. (I)KCNA5 knockout strategy based on simultaneously transfecting 4 CRISPR/Cas9 nickase vectors targeting the 5' end of the 1-exon gene body. A mutant clone generated this way displayed homozygous deletions causing a frame shift and premature stop as illustrated at the bottom. (J) PCR spanning the mutation site validates the sequencing-verified frame shift-causing deletion in KCNA5fs/fs cells at the DNA and RNA levels. Image collected and cropped by CiteAb from the following publication (https://journal.frontiersin.org/article/10.3389/fphys.2017.00469/full), licensed under a CC-BY license. Not internally tested by R&D Systems.

Western Blot Detection of Human SOX2 by Western Blot View Larger

Detection of Human SOX2 by Western Blot Construction and expression of srRNA.A: Scheme of Self-Replicating srRNA constructs. B: Expression of reprogramming factors in OKS-iM 4F-srRNA, OKS-iG 4F-srRNA, OKS-iGM 5F-srRNA, and OKS-iGML 6F-srRNA on day 2 (left) and day 10 (right). BJ cells were co-transfected with srRNAs plus B18R mRNA (1:1 srRNA:B18R mRNA), selected with puromycin and cultured in Advanced DMEM/10% FBS for 10 days. C: qRT-PCR analysis of LIN28A and NANOG from 4F-srRNA and 5F-srRNA transfected BJ cells normalized to GAPDH. Cells were selected with puromycin after the transfection, and cultured in Advanced DMEM/10% FBS (Ad) or ES medium. Cells were collected on day 2, 4, 6, 8 and 10 for 5F-srRNA, and day 10 for 4F-srRNA (OKS-iM and OKS-iG). D: Immunoblot analysis of LIN28A and NANOG in 5F-srRNA transfected BJ cells on day 6 and 10. iPSC: iPSC clone generated with 5F-srRNA from BJ cells. Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/28750082), licensed under a CC-BY license. Not internally tested by R&D Systems.

Immunocytochemistry/ Immunofluorescence Detection of Human Human/Mouse/Rat SOX2 Antibody by Immunocytochemistry/ Immunofluorescence View Larger

Detection of Human Human/Mouse/Rat SOX2 Antibody by Immunocytochemistry/ Immunofluorescence The Majority of Ferret and Human, but Not Mouse, Sox2-Positive Tbr2-Negative BPs Exhibit Nuclear YAP. (G and H) that are shown at higher magnification (F′, F″, G′, G″, H′, and H″), as indicated; selected Tbr2-positive nuclei that are YAP negative in mouse, ferret, and human are outlined by white lines.(I–K) Quantification of the percentage of Tbr2-negative nuclei in the VZ (I), Tbr2-positive nuclei in the VZ (J), and Tbr2-positive nuclei in the SVZ (K) that are YAP positive in mouse E14.5, ferret E36, and human 11 wpc neocortex. Two or three images per embryo-fetus were taken, 30 randomly picked Tbr2-negative nuclei in the VZ (I) and Tbr2-positive nuclei in the VZ (J) and SVZ (K) were scored per image, and the values obtained were averaged for each embryo-fetus. Data are the mean of three or four embryos-fetuses.(A–C and F–H) Images are 1-μm optical sections. Scale bars represent 50 μm (A–C and F–H), 10 μm (A′, B′, and C′), and 20 μm (F′, F″, G′, G″, H′, and H″).(D, E, and I–K) Error bars indicate SEM; ∗∗p < 0.01, ∗∗∗p < 0.001 (one-way ANOVA, post hoc Tukey HSD).See also Figures S1 and S2. Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/31018127), licensed under a CC-BY license. Not internally tested by R&D Systems.

Immunocytochemistry/ Immunofluorescence Detection of Human Human/Mouse/Rat SOX2 Antibody by Immunocytochemistry/ Immunofluorescence View Larger

Detection of Human Human/Mouse/Rat SOX2 Antibody by Immunocytochemistry/ Immunofluorescence The Majority of Ferret and Human, but Not Mouse, Sox2-Positive Tbr2-Negative BPs Exhibit Nuclear YAP(A–C) Double immunofluorescence for YAP (green) and Sox2 (magenta), combined with DAPI staining (white), of mouse E14.5 (A), ferret E36 (B), and human 14 wpc (C) neocortex. Boxes indicate areas in the SVZ (A) and oSVZ (B and C) that are shown at higher magnification (A′, B′, and C′); selected Sox2-positive nuclei that are YAP negative in mouse and YAP positive in ferret and human are outlined by white lines; arrowheads indicate a YAP-positive basal process of a bRG. Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/31018127), licensed under a CC-BY license. Not internally tested by R&D Systems.

Immunocytochemistry/ Immunofluorescence Detection of Mouse Human/Mouse/Rat SOX2 Antibody by Immunocytochemistry/ Immunofluorescence View Larger

Detection of Mouse Human/Mouse/Rat SOX2 Antibody by Immunocytochemistry/ Immunofluorescence The Majority of Ferret and Human, but Not Mouse, Sox2-Positive Tbr2-Negative BPs Exhibit Nuclear YAP.(F–H) Double immunofluorescence for YAP (green) and Tbr2 (magenta), combined with DAPI staining (white), of mouse E14.5 (F), ferret E36 (G), and human 11 wpc (H) neocortex. Boxes indicate areas in the VZ and SVZ (F) or iSVZ (G and H) that are shown at higher magnification (F′, F″, G′, G″, H′, and H″), as indicated; selected Tbr2-positive nuclei that are YAP negative in mouse, ferret, and human are outlined by white lines.(I–K) Quantification of the percentage of Tbr2-negative nuclei in the VZ (I), Tbr2-positive nuclei in the VZ (J), and Tbr2-positive nuclei in the SVZ (K) that are YAP positive in mouse E14.5, ferret E36, and human 11 wpc neocortex. Two or three images per embryo-fetus were taken, 30 randomly picked Tbr2-negative nuclei in the VZ (I) and Tbr2-positive nuclei in the VZ (J) and SVZ (K) were scored per image, and the values obtained were averaged for each embryo-fetus. Data are the mean of three or four embryos-fetuses.(A–C and F–H) Images are 1-μm optical sections. Scale bars represent 50 μm (A–C and F–H), 10 μm (A′, B′, and C′), and 20 μm (F′, F″, G′, G″, H′, and H″).(D, E, and I–K) Error bars indicate SEM; ∗∗p < 0.01, ∗∗∗p < 0.001 (one-way ANOVA, post hoc Tukey HSD).See also Figures S1 and S2. Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/31018127), licensed under a CC-BY license. Not internally tested by R&D Systems.

Immunocytochemistry/ Immunofluorescence Detection of Human Human/Mouse/Rat SOX2 Antibody by Immunocytochemistry/ Immunofluorescence View Larger

Detection of Human Human/Mouse/Rat SOX2 Antibody by Immunocytochemistry/ Immunofluorescence The Majority of Ferret and Human, but Not Mouse, Sox2-Positive Tbr2-Negative BPs Exhibit Nuclear YAP(A–C) Double immunofluorescence for YAP (green) and Sox2 (magenta), combined with DAPI staining (white), of mouse E14.5 (A), ferret E36 (B), and human 14 wpc (C) neocortex. Boxes indicate areas in the SVZ (A) and oSVZ (B and C) that are shown at higher magnification (A′, B′, and C′); selected Sox2-positive nuclei that are YAP negative in mouse and YAP positive in ferret and human are outlined by white lines; arrowheads indicate a YAP-positive basal process of a bRG.Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/31018127), licensed under a CC-BY license. Not internally tested by R&D Systems.

Preparation and Storage

Reconstitution
Reconstitute at 0.2 mg/mL in sterile PBS.
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Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: SOX2

SOX2 belongs to the SOX (SRY-like HMG box) family of transcription factors with diverse roles in development. SOX2 functions in specifying the first three lineages present at implantation and in regulating proliferation and differentiation in the developing peripheral nervous system (1-5).

References
  1. Graham, V. et al. (2003) Neuron 39:749.
  2. Avilion, A.A. et al. (2003) Genes Dev. 17:126.
  3. Kishi, M. et al. (2000) Development 127:791.
  4. Yuan, H. et al. (1995) Genes Dev. 9:2635.
  5. Uwanogho, D. et al. (1995) Mech. Dev. 49:23.
  6. Stevanovic, M. (2003) Mol. Biol. Rep. 30:127.
Long Name
Transcription Factor SOX2
Entrez Gene IDs
6657 (Human)
Alternate Names
ANOP3; MCOPS3; MGC2413; SOX2; SRY (sex determining region Y)-box 2; SRY-related HMG-box gene 2; transcription factor SOX2; transcription factor SOX-2

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Citations for Human/Mouse/Rat SOX2 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

369 Citations: Showing 1 - 10
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  1. Asynchronous excitatory neuron development in an isogenic cortical spheroid model of Down syndrome
    Authors: Z Li, JA Klein, S Rampam, R Kurzion, NB Campbell, Y Patel, TF Haydar, E Zeldich
    Frontiers in Neuroscience, 2022-09-07;16(0):932384.
  2. The Proliferation of Dentate Gyrus Progenitors in the Ferret Hippocampus by Neonatal Exposure to Valproic Acid
    Authors: Kazuhiko Sawada, Shiori Kamiya, Ichio Aoki
    Frontiers in Neuroscience
  3. Isogenic Pairs of Wild Type and Mutant Induced Pluripotent Stem Cell (iPSC) Lines from Rett Syndrome Patients as In Vitro Disease Model
    Authors: Gene Ananiev, Emily Cunningham Williams, Hongda Li, Qiang Chang
    PLoS ONE
  4. Intermediate Progenitors Facilitate Intracortical Progression of Thalamocortical Axons and Interneurons through CXCL12 Chemokine Signaling
    Authors: Philipp Abe, Zoltán Molnár, Yi-Shiuan Tzeng, Dar-Ming Lai, Sebastian J. Arnold, Ralf Stumm
    The Journal of Neuroscience
  5. Vascularized Tissue-Engineered Model for Studying Drug Resistance in Neuroblastoma
    Authors: A. Villasante, K. Sakaguchi, J. Kim, N.K. Cheung, M. Nakayama, H. Parsa et al.
    Theranostics
  6. Distinct functions of Sox2 control self-renewal and differentiation in the osteoblast lineage.
    Authors: Seo E, Basu-Roy U, Zavadil J et al.
    Mol Cell Biol.
  7. Sociosexual behavior requires both activating and repressive roles of Tfap2e/AP-2 epsilon in vomeronasal sensory neurons
    Authors: Jennifer M Lin, Tyler A Mitchell, Megan Rothstein, Alison Pehl, Ed Zandro M Taroc, Raghu R Katreddi et al.
    eLife
  8. In-depth comparison of Anc80L65 and AAV9 retinal targeting and characterization of cross-reactivity to multiple AAV serotypes in humans
    Authors: Maura K. Schwartz, Shibi Likhite, Tatyana A. Vetter, Megan C. Baird, Vicki McGovern, Andrea Sierra Delgado et al.
    Molecular Therapy - Methods & Clinical Development
  9. Axud1 Integrates Wnt Signaling and Transcriptional Inputs to Drive Neural Crest Formation
    Authors: Marcos Simões-Costa, Michael Stone, Marianne E. Bronner
    Developmental Cell
  10. Generation of mouse hippocampal brain organoids from primary embryonic neural stem cells
    Authors: Francesca Ciarpella, Raluca Georgiana Zamfir, Alessandra Campanelli, Giulia Pedrotti, Marzia Di Chio, Emanuela Bottani et al.
    STAR Protocols
  11. The subcommissural organ maintains features of neuroepithelial cells in the adult mouse
    Authors: Laarni Grace Corales, Hitoshi Inada, Kotaro Hiraoka, Shun Araki, Shinya Yamanaka, Takako Kikkawa et al.
    Journal of Anatomy
  12. Rewiring of human neurodevelopmental gene regulatory programs by human accelerated regions
    Authors: Girskis K, Stergachis A, DeGennaro E Et al.
    Neuron
  13. Injectable polypeptide hydrogels via methionine modification for neural stem cell delivery
    Authors: Wollenberg AL, O'Shea TM, Kim JH et al.
    Biomaterials
  14. Irx1 regulates dental outer enamel epithelial and lung alveolar type II epithelial differentiation
    Authors: Wenjie Yu, Xiao Li, Steven Eliason, Miguel Romero-Bustillos, Ryan J. Ries, Huojun Cao et al.
    Developmental Biology
  15. Loss of SRY-box2 (SOX2) expression and its impact on survival of patients with oesophageal adenocarcinoma
    Authors: F. J. C. ten Kate, S. H. van Olphen, M. J. Bruno, B. P. L. Wijnhoven, J. J. B. van Lanschot, L. H. J. Looijenga et al.
    British Journal of Surgery
  16. DOT1L activity affects neural stem cell division mode and reduces differentiation and ASNS expression
    Authors: Bismark Appiah, Camila L Fullio, Chiara Ossola, Ilaria Bertani, Elena Restelli, Arquimedes Cheffer et al.
    EMBO reports
  17. Human-specific ARHGAP11B is necessary and sufficient for human-type basal progenitor levels in primate brain organoids
    Authors: Jan Fischer, Eduardo Fernández Ortuño, Fabio Marsoner, Annasara Artioli, Jula Peters, Takashi Namba et al.
    EMBO Rep
  18. Subventricular zone/white matter microglia reconstitute the empty adult microglial niche in a dynamic wave
    Authors: Lindsay A Hohsfield, Allison R Najafi, Yasamine Ghorbanian, Neelakshi Soni, Joshua Crapser, Dario X Figueroa Velez et al.
    eLife
  19. Piezo1 forms a slowly-inactivating mechanosensory channel in mouse embryonic stem cells
    Authors: Josefina Inés del Mármol, Kouki K Touhara, Gist Croft, Roderick MacKinnon
    eLife
  20. Transplantable human motor networks as a neuron-directed strategy for spinal cord injury
    Authors: Zachary T. Olmsted, Cinzia Stigliano, Annalisa Scimemi, Tatiana Wolfe, Jose Cibelli, Philip J. Horner et al.
    iScience
  21. Directed differentiation of human pluripotent stem cells into diverse organ-specific mesenchyme of the digestive and respiratory systems
    Authors: K Kishimoto, K Iwasawa, A Sorel, C Ferran-Her, L Han, M Morimoto, JM Wells, T Takebe, AM Zorn
    Nature Protocols, 2022-08-17;0(0):.
  22. Stat1 is an inducible transcriptional repressor of neural stem cells self-renewal program during neuroinflammation
    Authors: Jaime Imitola, Ethan W. Hollingsworth, Fumihiro Watanabe, Marta Olah, Wassim Elyaman, Sarah Starossom et al.
    Frontiers in Cellular Neuroscience
  23. A hypomorphic mutation in Pold1 disrupts the coordination of embryo size expansion and morphogenesis during gastrulation
    Authors: Tingxu Chen, Heather Alcorn, Sujan Devbhandari, Dirk Remus, Elizabeth Lacy, Danwei Huangfu et al.
    Biology Open
  24. Chromatin dynamics through mouse preimplantation development revealed by single molecule localisation microscopy
    Authors: Marta Portela, Daniel Jimenez-Carretero, Veronica Labrador, Maria Jose Andreu, Elvira Arza, Valeria R. Caiolfa et al.
    Biology Open
  25. Horizontal Basal Cell-Specific Deletion of Pax6 Impedes Recovery of the Olfactory Neuroepithelium Following Severe Injury
    Authors: Jun Suzuki, Katsuyasu Sakurai, Maya Yamazaki, Manabu Abe, Hitoshi Inada, Kenji Sakimura et al.
    Stem Cells and Development
  26. Crosstalk between Glioma-Initiating Cells and Endothelial Cells Drives Tumor Progression
    Authors: Hye-Min Jeon, Sung-Hak Kim, Xun Jin, Jong Bae Park, Se Hoon Kim, Kaushal Joshi et al.
    Cancer Research
  27. Treatment and Prevention of Lung Cancer Using a Virus-Infected Reprogrammed Somatic Cell-Derived Tumor Cell Vaccination (VIReST) Regime
    Authors: Zhe Zhang, Shuangshuang Lu, Louisa S. Chard Dunmall, Zhizhong Wang, Zhenguo Cheng, Zhongxian Zhang et al.
    Frontiers in Immunology
  28. The aryl hydrocarbon receptor directs the differentiation of murine progenitor blastomeres
    Authors: Chia-I. Ko, Jacek Biesiada, Hesbon A. Zablon, Xiang Zhang, Mario Medvedovic, Alvaro Puga
    Cell Biology and Toxicology
  29. Breaking Mental Barriers Promotes Recovery After Spinal Cord Injury
    Authors: Haven I. Rodocker, Arman Bordbar, Molly J. E. Larson, Rebecca G. Biltz, Lynde Wangler, Paolo Fadda et al.
    Frontiers in Molecular Neuroscience
  30. Enhanced generation of iPSCs from older adult human cells by a synthetic five-factor self-replicative RNA
    Authors: Naohisa Yoshioka, Steven F. Dowdy
    PLOS ONE
  31. Induction of myelinating oligodendrocytes in human cortical spheroids
    Authors: M Madhavan, ZS Nevin, HE Shick, E Garrison, C Clarkson-P, M Karl, BLL Clayton, DC Factor, KC Allan, L Barbar, T Jain, P Douvaras, V Fossati, RH Miller, PJ Tesar
    Nat. Methods, 2018-07-25;0(0):.
  32. Fgf and Esrrb integrate epigenetic and transcriptional networks that regulate self-renewal of trophoblast stem cells
    Authors: Paulina A. Latos, Angela Goncalves, David Oxley, Hisham Mohammed, Ernest Turro, Myriam Hemberger
    Nature Communications
  33. A brain precursor atlas reveals the acquisition of developmental-like states in adult cerebral tumours
    Authors: Hamed AA, Kunz DJ, El-Hamamy I et al.
    Nature communications
  34. The Purinergic Receptor P2rx3 is Required for Spiral Ganglion Neuron Branch Refinement during Development
    Authors: Zhirong Wang, Johnny S. Jung, Talya C. Inbar, Katherine M. Rangoussis, Christian Faaborg-Andersen, Thomas M. Coate
    eNeuro
  35. R-SPONDIN2+ mesenchymal cells form the bud tip progenitor niche during human lung development
    Authors: Renee F.C. Hein, Joshua H. Wu, Emily M. Holloway, Tristan Frum, Ansley S. Conchola, Yu-Hwai Tsai et al.
    Developmental Cell
  36. SOX2 gene amplification and protein overexpression are associated with better outcome in squamous cell lung cancer
    Authors: Theresia Wilbertz, Patrick Wagner, Karen Petersen, Ann-Cathrin Stiedl, Veit J Scheble, Sebastian Maier et al.
    Modern Pathology
  37. Testicular somatic cell-like cells derived from embryonic stem cells induce differentiation of epiblasts into germ cells
    Authors: Rore H, Owen N, Pina-Aguilar Re Et Al.
    Communications biology
  38. Generation of esophageal organoids and organotypic raft cultures from human pluripotent stem cells
    Authors: Vered Shacham-Silverberg, James M. Wells
    Methods in Cell Biology
  39. Genomic Rewiring of SOX2 Chromatin Interaction Network during Differentiation of ESCs to Postmitotic Neurons
    Authors: Daria Bunina, Nade Abazova, Nichole Diaz, Kyung-Min Noh, Jeroen Krijgsveld, Judith B. Zaugg
    Cell Systems
  40. CRIPTO Is a Marker of Chemotherapy-Induced Stem Cell Expansion in Non-Small Cell Lung Cancer
    Authors: Federica Francescangeli, Maria Laura De Angelis, Rachele Rossi, Giovanni Sette, Adriana Eramo, Alessandra Boe et al.
    Frontiers in Oncology
  41. Sox-2 Positive Neural Progenitors in the Primate Striatum Undergo Dynamic Changes after Dopamine Denervation
    Authors: Cristina Ordoñez, Paz Moreno-Murciano, Maria Hernandez, Carla Di Caudo, Iñaki-Carril Mundiñano, Iñaki Carril-Mundiñano et al.
    PLoS ONE
  42. A combined human gastruloid model of cardiogenesis and neurogenesis
    Authors: Olmsted ZT, Paluh JL.
    iScience
  43. Patterning and gastrulation defects caused by the tw18 lethal are due to loss of Ppp2r1a
    Authors: Lisette Lange, Matthias Marks, Jinhua Liu, Lars Wittler, Hermann Bauer, Sandra Piehl et al.
    Biology Open
  44. The pathogenesis of common Gjb2 mutations associated with human hereditary deafness in mice
    Authors: Qing Li, Chong Cui, Rongyu Liao, Xidi Yin, Daqi Wang, Yanbo Cheng et al.
    Cellular and Molecular Life Sciences
  45. Optimized protocol for analysis of neural stem proliferation in human-pluripotent-stem-cell-derived cerebral organoids
    Authors: Xiao-Yan Tang, Da Wang, Xin-Yue Zhang, Min Xu, Yan Liu
    STAR Protocols
  46. The miR-200 family is required for ectodermal organ development through the regulation of the epithelial stem cell niche
    Authors: Mason Sweat, Yan Sweat, Wenjie Yu, Dan Su, Riley J. Leonard, Steven L. Eliason et al.
    Stem Cells
  47. A robust protocol for the generation of human midbrain organoids
    Authors: Alise Zagare, Matthieu Gobin, Anna S. Monzel, Jens C. Schwamborn
    STAR Protocols
  48. In vitro Differentiation of TERT-Transfected Multi-Lineage Progenitor Cells (MLPC) into Immortalized Hepatocyte-Like Cells
    Authors: Collins D, Hapke J, Aravalli R, Steer C
    HMER
  49. Isolation of Neural Stem Cells from Whole Brain Tissues of Adult Mice
    Authors: Krutika Deshpande, Behnaz Saatian, Vahan Martirosian, Michelle Lin, Alex Julian, Josh Neman
    Current Protocols in Stem Cell Biology
  50. SOX2 Drives Bronchial Dysplasia in a Novel Organotypic Model of Early Human Squamous Lung Cancer
    Authors: Lúcia L. Correia, Jo-Anne Johnson, Peter McErlean, Julien Bauer, Hassan Farah, Doris M. Rassl et al.
    American Journal of Respiratory and Critical Care Medicine
  51. Wnt Signaling Regulates the Lineage Differentiation Potential of Mouse Embryonic Stem Cells through Tcf3 Down-Regulation
    Authors: Yaser Atlasi, Rubina Noori, Claudia Gaspar, Patrick Franken, Andrea Sacchetti, Haleh Rafati et al.
    PLoS Genetics
  52. Recapitulating porcine cardiac development in vitro: from expanded potential stem cell to embryo culture models
    Authors: Hilansi Rawat, Jessica Kornherr, Dorota Zawada, Sara Bakhshiyeva, Christian Kupatt, Karl-Ludwig Laugwitz et al.
    Frontiers in Cell and Developmental Biology
  53. Neural presbycusis at ultra-high frequency in aged common marmosets and rhesus monkeys
    Authors: Sun Z, Cheng Z, Gong N et al.
    Aging (Albany NY)
  54. Characterization of Strip1 Expression in Mouse Cochlear Hair Cells
    Authors: Shasha Zhang, Ying Dong, Ruiying Qiang, Yuan Zhang, Xiaoli Zhang, Yin Chen et al.
    Frontiers in Genetics
  55. Analysis of SOX2 expression in developing human testis and germ cell neoplasia
    Authors: Si B. Sonne, Rebecca M. Perrett, John E. Nielsen, Melissa A. Baxter, David M. Kristensen, Henrik Leffers et al.
    The International Journal of Developmental Biology
  56. TFAP2C regulates transcription in human naive pluripotency by opening enhancers
    Authors: WA Pastor, W Liu, D Chen, J Ho, R Kim, TJ Hunt, A Lukianchik, X Liu, JM Polo, SE Jacobsen, AT Clark
    Nat. Cell Biol., 2018-04-25;20(5):553-564.
  57. Glucocorticoids Target Ependymal Glia and Inhibit Repair of the Injured Spinal Cord
    Authors: Craig M. Nelson, Vanda A. Lennon, Han Lee, Randall G. Krug, Aichurok Kamalova, Nicolas N. Madigan et al.
    Frontiers in Cell and Developmental Biology
  58. NF-?B Activity Initiates Human ESC-Derived Neural Progenitor Cell Differentiation by Inducing a Metabolic Maturation Program
    Authors: LM FitzPatric, KE Hawkins, JMKM Delhove, E Fernandez, C Soldati, LF Bullen, A Nohturfft, SN Waddington, DL Medina, JP Bolaños, TR McKay
    Stem Cell Reports, 2018-04-19;0(0):.
  59. Pannexin 1 Influences Lineage Specification of Human iPSCs
    Authors: Rebecca J. Noort, Grace A. Christopher, Jessica L. Esseltine
    Frontiers in Cell and Developmental Biology
  60. Single-cell atlas of early human brain development highlights heterogeneity of human neuroepithelial cells and early radial glia
    Authors: Ugomma C. Eze, Aparna Bhaduri, Maximilian Haeussler, Tomasz J. Nowakowski, Arnold R. Kriegstein
    Nature Neuroscience
  61. Comparative regenerative biology of spiny ( Acomys cahirinus) and laboratory ( Mus musculus) mouse skin
    Authors: Ting‐Xin Jiang, Hans I‐Chen Harn, Kuang‐Ling Ou, Mingxing Lei, Cheng‐Ming Chuong
    Experimental Dermatology
  62. Generation of Human iPSC-derived Neural Progenitor Cells (NPCs) as Drug Discovery Model for Neurological and Mitochondrial Disorders
    Authors: Annika Zink, Pawel Lisowski, Alessandro Prigione
    BIO-PROTOCOL
  63. Single-cell multiome sequencing clarifies enteric glial diversity and identifies an intraganglionic population poised for neurogenesis
    Authors: Richard A. Guyer, Rhian Stavely, Keiramarie Robertson, Sukhada Bhave, Jessica L. Mueller, Nicole M. Picard et al.
    Cell Reports
  64. The Pluripotency Factor-Bound Intron 1 of Xist Is Dispensable for X Chromosome Inactivation and Reactivation In Vitro and In Vivo
    Authors: Alissa Minkovsky, Tahsin Stefan Barakat, Nadia Sellami, Mark Henry Chin, Nilhan Gunhanlar, Joost Gribnau et al.
    Cell Reports
  65. Inhibiting USP16 rescues stem cell aging and memory in an Alzheimer’s model
    Authors: Felicia Reinitz, Elizabeth Y Chen, Benedetta Nicolis di Robilant, Bayarsaikhan Chuluun, Jane Antony, Robert C Jones et al.
    eLife
  66. Evolution and cell-type specificity of human-specific genes preferentially expressed in progenitors of fetal neocortex
    Authors: Marta Florio, Michael Heide, Anneline Pinson, Holger Brandl, Mareike Albert, Sylke Winkler et al.
    eLife
  67. Glycolysis-Independent Glucose Metabolism Distinguishes TE from ICM Fate during Mammalian Embryogenesis.
    Authors: Chi F, Sharpley M, Nagaraj R et al.
    Dev Cell.
  68. Müller glia-derived PRSS56 is required to sustain ocular axial growth and prevent refractive error
    Authors: Seyyedhassan Paylakhi, Cassandre Labelle-Dumais, Nicholas G Tolman, Michael A. Sellarole, Yusef Seymens, Joseph Saunders et al.
    PLOS Genetics
  69. Haemorrhage of human foetal cortex associated with SARS-CoV-2 infection
    Authors: Marco Massimo, Carlotta Barelli, Catalina Moreno, Chiara Collesi, Rebecca K Holloway, Berta Crespo et al.
    Brain
  70. A Micropatterned Human‐Specific Neuroepithelial Tissue for Modeling Gene and Drug‐Induced Neurodevelopmental Defects
    Authors: Geetika Sahni, Shu‐Yung Chang, Jeremy Teo Choon Meng, Jerome Zu Yao Tan, Jean Jacques Clement Fatien, Carine Bonnard et al.
    Advanced Science
  71. Temporal BMP4 effects on mouse embryonic and extraembryonic development
    Authors: Hadas, R;Rubinstein, H;Mittnenzweig, M;Mayshar, Y;Ben-Yair, R;Cheng, S;Aguilera-Castrejon, A;Reines, N;Orenbuch, AH;Lifshitz, A;Chen, DY;Elowitz, MB;Zernicka-Goetz, M;Hanna, JH;Tanay, A;Stelzer, Y;
    Nature
    Species: Mouse
    Sample Types: Embryo
    Applications: Immunohistochemistry
  72. Contributions of mirror-image hair cell orientation to mouse otolith organ and zebrafish neuromast function
    Authors: Ono, K;Jarysta, A;Hughes, NC;Jukic, A;Chang, HHV;Deans, MR;Eatock, RA;Cullen, KE;Kindt, K;Tarchini, B;
    bioRxiv : the preprint server for biology
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  73. Morphogenic, molecular, and cellular adaptations for unidirectional airflow in the chicken lung
    Authors: Gerner-Mauro, KN;Ellis, LV;Wang, G;Nayak, R;Lwigale, PY;Poché, RA;Chen, J;
    bioRxiv : the preprint server for biology
    Species: Chicken, Mouse
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  74. Dopaminergic progenitors generated by small molecule approach survived, integrated, and promoted functional recovery in (6-OHDA) mouse model of Parkinson's disease
    Authors: Alexanian, AR;Sorokin, A;Duersteler, M;
    Journal of the neurological sciences
    Species: Human
    Sample Types: Whole Cells
    Applications: Immunocytochemistry
  75. A multiomic atlas of the aging hippocampus reveals molecular changes in response to environmental enrichment
    Authors: Pérez, RF;Tezanos, P;Peñarroya, A;González-Ramón, A;Urdinguio, RG;Gancedo-Verdejo, J;Tejedor, JR;Santamarina-Ojeda, P;Alba-Linares, JJ;Sainz-Ledo, L;Roberti, A;López, V;Mangas, C;Moro, M;Cintado Reyes, E;Muela Martínez, P;Rodríguez-Santamaría, M;Ortea, I;Iglesias-Rey, R;Castilla-Silgado, J;Tomás-Zapico, C;Iglesias-Gutiérrez, E;Fernández-García, B;Sanchez-Mut, JV;Trejo, JL;Fernández, AF;Fraga, MF;
    Nature communications
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  76. Early human fetal lung atlas reveals the temporal dynamics of epithelial cell plasticity
    Authors: Quach, H;Farrell, S;Wu, MJM;Kanagarajah, K;Leung, JW;Xu, X;Kallurkar, P;Turinsky, AL;Bear, CE;Ratjen, F;Kalish, B;Goyal, S;Moraes, TJ;Wong, AP;
    Nature communications
    Species: Human
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  77. Impact of subthalamic nucleus deep brain stimulation at different frequencies on neurogenesis in a rat model of Parkinson's disease
    Authors: Wu, Z;Ren, Z;Gao, R;Sun, K;Sun, F;Liu, T;Zheng, S;Wang, W;Zhang, G;
    Heliyon
    Species: Rat
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  78. Translocation of telomerase reverse transcriptase coincided with ATP release in postnatal cochlear supporting cells
    Authors: Zhang, Y;Tian, K;Wei, W;Mi, W;Lu, F;Liu, Z;Zhu, Q;Zhang, X;Geng, P;Qiu, J;Song, Y;Zha, D;
    Neural regeneration research
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  79. IFI35 regulates non-canonical NF-?B signaling to maintain glioblastoma stem cells and recruit tumor-associated macrophages
    Authors: Li, D;Wang, X;Chen, K;Shan, D;Cui, G;Yuan, W;Lin, Q;Gimple, RC;Dixit, D;Lu, C;Gu, D;You, H;Gao, J;Li, Y;Kang, T;Yang, J;Yu, H;Song, K;Shi, Z;Fan, X;Wu, Q;Gao, W;Zhu, Z;Man, J;Wang, Q;Lin, F;Tao, W;Mack, SC;Chen, Y;Zhang, J;Li, C;Zhang, N;You, Y;Qian, X;Yang, K;Rich, JN;Zhang, Q;Wang, X;
    Cell death and differentiation
    Species: Xenograft
    Sample Types: Whole Cells, Whole Tissue
    Applications: Immunohistochemistry, Immunocytochemistry
  80. Rbm8a regulates neurogenesis and reduces Alzheimer's disease-associated pathology in the dentate gyrus of 5×FAD mice
    Authors: Zhu, C;Ren, X;Liu, C;Liu, Y;Wang, Y;
    Neural regeneration research
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  81. Generation of three isogenic gene-edited Huntington's disease human embryonic stem cell lines with DOX-inducible NGN2 expression cassette in the AAVS1 safe locus
    Authors: Villegas, LD;Chandrasekaran, A;Andersen, SAF;Nørremølle, A;Schmid, B;Pouladi, MA;Freude, K;
    Stem cell research
    Species: Human
    Sample Types: cell line
    Applications: Flow Cyomtetry, ICC-IF
  82. Noncanonical function of folate through folate receptor 1 during neural tube formation
    Authors: Balashova, OA;Panoutsopoulos, AA;Visina, O;Selhub, J;Knoepfler, PS;Borodinsky, LN;
    Nature communications
    Species: Xenopus, Human
    Sample Types: Embryo, Organoid
    Applications: IHC
  83. Human cerebellar organoids with functional Purkinje cells
    Authors: Atamian, A;Birtele, M;Hosseini, N;Nguyen, T;Seth, A;Del Dosso, A;Paul, S;Tedeschi, N;Taylor, R;Coba, MP;Samarasinghe, R;Lois, C;Quadrato, G;
    Cell stem cell
    Species: Human
    Sample Types: Organoid
    Applications: Immunohistochemistry
  84. Stabilization of Pin1 by USP34 promotes Ubc9 isomerization and protein sumoylation in glioma stem cells
    Authors: Zhu, Q;Liang, P;Meng, H;Li, F;Miao, W;Chu, C;Wang, W;Li, D;Chen, C;Shi, Y;Yu, X;Ping, Y;Niu, C;Wu, HB;Zhang, A;Bian, XW;Zhou, W;
    Nature communications
    Species: Human, Xenograft
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  85. Fatty acid binding protein type 7 deficiency preserves auditory function in noise-exposed mice
    Authors: Suzuki, J;Hemmi, T;Maekawa, M;Watanabe, M;Inada, H;Ikushima, H;Oishi, T;Ikeda, R;Honkura, Y;Kagawa, Y;Kawase, T;Mano, N;Owada, Y;Osumi, N;Katori, Y;
    Scientific reports
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  86. Brain-Specific Angiogenesis Inhibitor 3 Is Expressed in the Cochlea and Is Necessary for Hearing Function in Mice
    Authors: Saegusa, C;Kakegawa, W;Miura, E;Aimi, T;Mogi, S;Harada, T;Yamashita, T;Yuzaki, M;Fujioka, M;
    International journal of molecular sciences
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  87. Generation of locus coeruleus norepinephrine neurons from human pluripotent stem cells
    Authors: Tao, Y;Li, X;Dong, Q;Kong, L;Petersen, AJ;Yan, Y;Xu, K;Zima, S;Li, Y;Schmidt, DK;Ayala, M;Mathivanan, S;Sousa, AMM;Chang, Q;Zhang, SC;
    Nature biotechnology
    Species: Mouse
    Sample Types: Whole Cells, Whole Tissue
    Applications: IHC, Flow Cytometry
  88. Generation of the iPSC line FINi002-A from a male Parkinson's disease patient carrying compound heterozygous mutations in the PRKN gene
    Authors: Pavan, C;Jin, J;Jong, S;Strbenac, D;Davis, RL;Sue, CM;Johnston, J;Lynch, T;Halliday, G;Kirik, D;Parish, CL;Thompson, LH;Ovchinnikov, DA;
    Stem cell research
    Species: Human
    Sample Types: Whole Cells
    Applications: Immunocytochemistry
  89. SOX9-positive pituitary stem cells differ according to their position in the gland and maintenance of their progeny depends on context
    Authors: Rizzoti, K;Chakravarty, P;Sheridan, D;Lovell-Badge, R;
    Science advances
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  90. Wolf-Hirschhorn Syndrome Candidate 1 (Whsc1) Methyltransferase Signals Via a Pitx2-miR-23/24 Axis to Effect Tooth Development
    Authors: Su, D;Eliason, S;Sun, Z;Shao, F;Amendt, BA;
    The Journal of biological chemistry
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  91. Aberrant pace of cortical neuron development in brain organoids from patients with 22q11.2 deletion syndrome and schizophrenia
    Authors: Rao, SB;Brundu, F;Chen, Y;Sun, Y;Zhu, H;Shprintzen, RJ;Tomer, R;Rabadan, R;Leong, KW;Markx, S;Xu, B;Gogos, JA;
    bioRxiv : the preprint server for biology
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  92. The Semaphorin 3A-Neuropilin-1 Pathway Promotes Clonogenic Growth of Glioblastoma via Activation of TGF? Signaling
    Authors: Jeon, HM;Shin, YJ;Lee, J;Chang, N;Woo, DH;Lee, WJ;Nguyen, D;Kang, W;Cho, HJ;Yang, H;Lee, JK;Sa, JK;Lee, Y;Kim, D;Purow, BW;Yoon, Y;Nam, DH;Lee, J;
    JCI insight
    Species: Human
    Sample Types: Tissue Microarray
    Applications: IHC-P
  93. Crosstalk between PARN and EGFR-STAT3 Signaling Facilitates Self-Renewal and Proliferation of Glioblastoma Stem Cells
    Authors: Yin, J;Seo, Y;Rhim, J;Jin, X;Kim, TH;Kim, SS;Hong, JH;Gwak, HS;Yoo, H;Park, JB;Kim, JH;
    Cancer research
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  94. RBL2-E2F-GCN5 guide cell fate decisions during tissue specification by regulating cell-cycle-dependent fluctuations of non-cell-autonomous signaling
    Authors: Militi, S;Nibhani, R;Jalali, M;Pauklin, S;
    Cell reports
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  95. Generation of an induced pluripotent stem cell line XJHi001-A from a fibronectin glomerulopathy patient carrying a heterozygous NM_212482.2(C.5888-1G > C) mutation in the FN1 gene
    Authors: She, L;Li, X;Bai, M;
    Stem cell research
    Species: Human
    Sample Types: Transfected Whole Cells
    Applications: ICC
  96. Engineered 3D Immuno-Glial-Neurovascular Human Brain Model
    Authors: Stanton, AE;Bubnys, A;Agbas, E;James, B;Park, DS;Jiang, A;Pinals, RL;Truong, N;Loon, A;Staab, C;Liu, L;Cerit, O;Wen, HL;Kellis, M;Blanchard, JW;Langer, RS;Tsai, LH;
    bioRxiv : the preprint server for biology
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  97. CD200 in dentate gyrus improves depressive-like behaviors of mice through enhancing hippocampal neurogenesis via alleviation of microglia hyperactivation
    Authors: Chen, X;Cui, QQ;Hu, XH;Ye, J;Liu, ZC;Mei, YX;Wang, F;Hu, ZL;Chen, JG;
    Journal of neuroinflammation
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  98. Scalable projected Light Sheet Microscopy for high-resolution imaging of large samples
    Authors: Chen, Y;Gong, C;Chauhan, S;De La Cruz, ED;Datta, MS;Tomer, R;
    bioRxiv : the preprint server for biology
    Species: Human
    Sample Types: Organoid
    Applications: Immunohistochemistry
  99. Mitotic bookmarking by SWI/SNF subunits
    Authors: Zhu, Z;Chen, X;Guo, A;Manzano, T;Walsh, PJ;Wills, KM;Halliburton, R;Radko-Juettner, S;Carter, RD;Partridge, JF;Green, DR;Zhang, J;Roberts, CWM;
    Nature
    Species: Mouse
    Sample Types: Cell Lysates, Whole Cells
    Applications: Bioassay, Western Blot, ICC
  100. Zinc finger and SCAN domain-containing 18 suppresses the proliferation, self-renewal, and drug resistance of glioblastoma cells
    Authors: Wang, Y;Peng, J;Song, C;Yang, Y;Qin, T;
    Heliyon
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  101. Early radial positional information in the cochlea is optimized by a precise linear BMP gradient and enhanced by SOX2
    Authors: Thompson, MJ;Young, CA;Munnamalai, V;Umulis, DM;
    Scientific reports
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  102. Cell Specificity of Manganese-enhanced MRI Signal in the Cerebellum
    Authors: Rallapalli, H;Bayin, NS;Goldman, H;Maric, D;Nieman, BJ;Koretsky, AP;Joyner, AL;Turnbull, DH;
    NeuroImage
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  103. Integrated transcriptome and proteome analysis reveals posttranscriptional regulation of ribosomal genes in human brain organoids
    Authors: J Sidhaye, P Trepte, N Sepke, M Novatchkov, M Schutzbier, G Dürnberger, K Mechtler, JA Knoblich
    Elife, 2023-03-29;12(0):.
    Species: Human
    Sample Types: Transfected Whole Cells, Whole Tissue
    Applications: ICC, IHC
  104. H3.3 contributes to chromatin accessibility and transcription factor binding at promoter-proximal regulatory elements in embryonic stem cells
    Authors: A Tafessu, R O'Hara, S Martire, AL Dube, P Saha, VU Gant, LA Banaszynsk
    Genome Biology, 2023-02-13;24(1):25.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Binding Assay
  105. Extracellular Vesicle Treatment Alleviates Neurodevelopmental and Neurodegenerative Pathology in Cortical Spheroid Model of Down Syndrome
    Authors: NB Campbell, Y Patel, TL Moore, M Medalla, E Zeldich
    International Journal of Molecular Sciences, 2023-02-09;24(4):.
    Species: Human
    Sample Types: Spheroid
    Applications: IHC
  106. Epitranscriptomic regulation of cortical neurogenesis via Mettl8-dependent mitochondrial tRNA m3C modification
    Authors: F Zhang, K Yoon, DY Zhang, NS Kim, GL Ming, H Song
    Cell Stem Cell, 2023-02-09;0(0):.
    Species: Human
    Sample Types: Organoid
    Applications: IHC
  107. A whole-genome scan for Artemisinin cytotoxicity reveals a novel therapy for human brain tumors
    Authors: J Taubenschm, M Orthofer, A Laemmerer, C Krauditsch, M Rózsová, C Studer, D Lötsch, J Gojo, L Gabler, M Dyczynski, T Efferth, A Hagelkruys, G Widhalm, A Peyrl, S Spiegl-Kre, D Hoepfner, S Bian, W Berger, JA Knoblich, U Elling, M Horn, JM Penninger
    Embo Molecular Medicine, 2023-02-06;0(0):e16959.
    Species: Human
    Sample Types: Organoids
    Applications: IHC
  108. ZFP462 safeguards neural lineage specification by targeting G9A/GLP-mediated heterochromatin to silence enhancers
    Authors: R Yelagandul, K Stecher, M Novatchkov, L Michetti, G Michlits, J Wang, P Hofbauer, G Vainorius, C Pribitzer, L Isbel, S Mendjan, D Schübeler, U Elling, J Brennecke, O Bell
    Nature Cell Biology, 2023-01-05;0(0):.
    Species: Mouse
    Sample Types: Chromatin
    Applications: ChIP
  109. Advanced Maternal Age Differentially Affects Embryonic Tissues with the Most Severe Impact on the Developing Brain
    Authors: C Kokorudz, BN Radford, W Dean, M Hemberger
    Cells, 2022-12-24;12(1):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  110. Organoid modeling of human fetal lung alveolar development reveals mechanisms of cell fate patterning and neonatal respiratory disease
    Authors: K Lim, APA Donovan, W Tang, D Sun, P He, JP Pett, SA Teichmann, JC Marioni, KB Meyer, AH Brand, EL Rawlins
    Cell Stem Cell, 2022-12-08;30(1):20-37.e9.
    Species: Human
    Sample Types: Organoid
    Applications: IHC
  111. The oncogenic JAG1 intracellular domain is a transcriptional cofactor that acts in concert with DDX17/SMAD3/TGIF2
    Authors: EJ Kim, JY Kim, SO Kim, N Hong, SH Choi, MG Park, J Jang, SW Ham, S Seo, SY Lee, K Lee, HJ Jeong, SJ Kim, S Jeong, K Min, SC Kim, X Jin, SH Kim, SH Kim, H Kim
    Cell Reports, 2022-11-22;41(8):111626.
    Species: Transgenic Mouse
    Sample Types: Cell Lysates
    Applications: Western Blot
  112. Simultaneous depletion of RB, RBL1 and RBL2 affects endoderm differentiation of human embryonic stem cells
    Authors: S Nakanoh, J Kadiwala, L Pinte, CM Morell, AS Lenaerts, L Vallier
    PLoS ONE, 2022-11-22;17(11):e0269122.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  113. BNIP3-dependent mitophagy safeguards ESC genomic integrity via preventing oxidative stress-induced DNA damage and protecting homologous recombination
    Authors: Q Zhao, K Liu, L Zhang, Z Li, L Wang, J Cao, Y Xu, A Zheng, Q Chen, T Zhao
    Cell Death & Disease, 2022-11-19;13(11):976.
    Species: Transgenic Mouse
    Sample Types: Whole Cells
    Applications: IHC
  114. Hierarchical deployment of Tbx3 dictates the identity of hypothalamic KNDy neurons to control puberty onset
    Authors: X Shi, Y Zhuang, Z Chen, M Xu, J Kuang, XL Sun, L Gao, X Kuang, H Zhang, W Li, SZH Wong, C Liu, L Liu, D Jiang, D Pei, Y Lin, QF Wu
    Science Advances, 2022-11-16;8(46):eabq2987.
    Species: Mouse
    Sample Types: Whole Cells, Whole Tissue
    Applications: ICC, IHC
  115. Vestibular Nuclei: A New Neural Stem Cell Niche?
    Authors: G Rastoldo, I Watabe, A Lapotre, A Tonetto, A López-Juár, B Tighilet
    Cells, 2022-11-14;11(22):.
    Species: Rat
    Sample Types: Whole Tissue
    Applications: IHC
  116. A single-cell transcriptome atlas of glial diversity in the human hippocampus across the postnatal lifespan
    Authors: Y Su, Y Zhou, ML Bennett, S Li, M Carceles-C, L Lu, S Huh, D Jimenez-Cy, BC Kennedy, SK Kessler, AN Viaene, I Helbig, X Gu, JE Kleinman, TM Hyde, DR Weinberger, DW Nauen, H Song, GL Ming
    Cell Stem Cell, 2022-11-03;29(11):1594-1610.e8.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  117. Immediate protein expression from exogenous mRNAs in embryonic brain
    Authors: M Naruse, T Saito
    Scientific Reports, 2022-10-13;12(1):17145.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  118. Human PSCs determine the competency of cerebral organoid differentiation via FGF signaling and epigenetic mechanisms.
    Authors: Ideno H, Imaizumi K, Shimada H, Sanosaka T, Nemoto A, Kohyama J, Okano H
    iScience, 2022-09-16;25(10):105140.
    Species: Human
    Sample Types: Organoid
    Applications: IHC
  119. beta2-microglobulin maintains glioblastoma stem cells and induces M2-like polarization of tumor-associated macrophages
    Authors: D Li, Q Zhang, L Li, K Chen, J Yang, D Dixit, RC Gimple, S Ci, C Lu, L Hu, J Gao, D Shan, Y Li, J Zhang, ZM Shi, D Gu, W Yuan, Q Wu, K Yang, L Zhao, Z Qiu, D Lv, W Gao, H Yang, F Lin, Q Wang, J Man, C Li, W Tao, S Agnihotri, X Qian, Y Shi, Y You, N Zhang, JN Rich, X Wang
    Oncogene, 2022-09-16;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  120. Generation of a human induced pluripotent stem cell line (LZUSHi002-A) from a MADD patient with ETFDH mutation
    Authors: Y Li, Y Li, H Liu, L Cheng, H Ma, X Xu, N Zhang
    Stem Cell Research, 2022-09-14;64(0):102914.
    Species: Human
    Sample Types: Whole Cells
    Applications: IHC
  121. Progesterone Receptor Modulates Extraembryonic Mesoderm and Cardiac Progenitor Specification during Mouse Gastrulation
    Authors: AM Drozd, L Mariani, X Guo, V Goitea, NA Menezes, E Ferretti
    International Journal of Molecular Sciences, 2022-09-07;23(18):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC/IF
  122. CHD4 mediates SOX2 transcription through TRPS1 in luminal breast cancer
    Authors: J Zhang, X Lv, B Wei, X Gong, L Chen
    Cellular Signalling, 2022-09-06;100(0):110464.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  123. SOX transcription factors direct TCF-independent WNT/beta-catenin responsive transcription to govern cell fate in human pluripotent stem cells
    Authors: S Mukherjee, DM Luedeke, L McCoy, M Iwafuchi, AM Zorn
    Cell Reports, 2022-08-23;40(8):111247.
    Species: Human
    Sample Types: Whole Cells
    Applications: IF
  124. SHH and Notch regulate SOX9+ progenitors to govern arcuate POMC neurogenesis
    Authors: E Place, E Manning, DW Kim, A Kinjo, G Nakamura, K Ohyama
    Frontiers in Neuroscience, 2022-08-11;16(0):855288.
    Species: Chicken
    Sample Types: Whole Cells
    Applications: ICC/IF
  125. Lgr5+ cells are required and dynamically participate in olfactory epithelium regeneration: a revisiting shows Lgr5 expression in multiple cell lineages
    Authors: W Ren, Z Ma, L Wang, X Feng, H Yu, Y Yu
    Theranostics, 2022-07-18;12(13):5631-5644.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  126. Non-coding de novo mutations in chromatin interactions are implicated in autism spectrum disorder
    Authors: IB Kim, T Lee, J Lee, J Kim, S Lee, IG Koh, JH Kim, JY An, H Lee, WK Kim, YS Ju, Y Cho, SJ Yu, SA Kim, M Oh, DW Han, E Kim, JK Choi, HJ Yoo, JH Lee
    Oncogene, 2022-07-15;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  127. Ubiquitination and deubiquitination of 4E-T regulate neural progenitor cell maintenance and neurogenesis by controlling P-body formation
    Authors: S Kedia, MR Aghanoori, KML Burns, M Subha, L Williams, P Wen, D Kopp, SL Erickson, EM Harvey, X Chen, M Hua, JU Perez, F Ishraque, G Yang
    Oncogene, 2022-07-12;40(2):111070.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  128. A combined human gastruloid model of cardiogenesis and neurogenesis
    Authors: Olmsted ZT, Paluh JL.
    iScience
  129. Functional Deficits of 5�FAD Neural Stem Cells Are Ameliorated by Glutathione Peroxidase 4
    Authors: NJ Dar, R Na, Q Ran
    Cells, 2022-05-28;11(11):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  130. Generation of an induced pluripotent stem cell line (DHMCi008-A) from an individual with TUBA1A tubulinopathy
    Authors: J Schröter, H Syring, G Göhring, S Kölker, T Opladen, GF Hoffmann, S Syrbe, S Jung-Klawi
    Stem Cell Research, 2022-05-24;62(0):102818.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  131. Critical roles of FGF, RA, and WNT signalling in the development of the human otic placode and subsequent lineages in a dish
    Authors: T Saeki, S Yoshimatsu, M Ishikawa, CC Hon, I Koya, S Shibata, M Hosoya, C Saegusa, K Ogawa, JW Shin, M Fujioka, H Okano
    Regenerative Therapy, 2022-05-16;20(0):165-186.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  132. Cranial irradiation-induced impairment of axonal transport and sexual function in male rats and imaging of the olfactory pathway by MRI
    Authors: Q Li, H Dai, F Ran, Y Luo, J Gao, A Deng, N Xu, C Liao, J Yang
    Neurotoxicology, 2022-05-14;0(0):.
    Species: Rat
    Sample Types: Tissue Homogenates
    Applications: Western Blot
  133. Effect of DHA on the quality of In�vitro produced bovine embryos
    Authors: S Janati Idr, V Slezec-Fri, D Le Bourhis, L Le Berre, T Joly, S Buff, A Desmarchai, L Schibler, P Salvetti, S Elis
    Theriogenology, 2022-04-30;187(0):102-111.
    Species: Bovine
    Sample Types: Embryos
    Applications: IHC
  134. Neurogenesis of Subventricular Zone Progenitors in the Premature Cortex of Ferrets Facilitated by Neonatal Valproic Acid Exposure
    Authors: K Sawada
    International Journal of Molecular Sciences, 2022-04-28;23(9):.
    Species: Ferret
    Sample Types: Whole Tissue
    Applications: IHC
  135. Amniogenesis occurs in two independent waves in primates
    Authors: M Rostovskay, S Andrews, W Reik, PJ Rugg-Gunn
    Cell Stem Cell, 2022-04-18;29(5):744-759.e6.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  136. Heme Oxygenase-1 Protects Hair Cells From Gentamicin-Induced Death
    Authors: Y Yang, X Chen, K Tian, C Tian, L Chen, W Mi, Q Li, J Qiu, Y Lin, D Zha
    Frontiers in Cellular Neuroscience, 2022-04-13;16(0):783346.
    Species: Rat
    Sample Types: Whole Tissue
    Applications: IHC
  137. Human distal lung maps and lineage hierarchies reveal a bipotent progenitor
    Authors: P Kadur Laks, V Sontake, A Tata, Y Kobayashi, L Macadlo, K Okuda, AS Conchola, S Nakano, S Gregory, LA Miller, JR Spence, JF Engelhardt, RC Boucher, JR Rock, SH Randell, PR Tata
    Nature, 2022-03-30;604(7904):111-119.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  138. Generation of an integration-free induced pluripotent stem cell line (LZUSHI001-A) from an epileptic patient with DGKG mutation
    Authors: YQ Liu, TW Ling, HY Wang, YH Yang, WJ Song, TC Wang
    Stem Cell Research, 2022-03-28;61(0):102768.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  139. Retinoic acid signaling mediates peripheral cone photoreceptor survival in a mouse model of retina degeneration
    Authors: R Amamoto, GK Wallick, CL Cepko
    Elife, 2022-03-22;11(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  140. 8C-like cells capture the human zygotic genome activation program in�vitro
    Authors: J Taubenschm, M Rostovskay, F Santos, S Ljung, R Argelaguet, F Krueger, J Nichols, W Reik
    Cell Stem Cell, 2022-02-24;29(3):449-459.e6.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  141. L-Thyroxine Improves Vestibular Compensation in a Rat Model of Acute Peripheral Vestibulopathy: Cellular and Behavioral Aspects
    Authors: G Rastoldo, E Marouane, N El-Mahmoud, D Péricat, I Watabe, A Lapotre, A Tonetto, A López-Juár, A El-Ahmadi, P Caron, ME Fraysse, C Chabbert, A Zwergal, B Tighilet
    Cells, 2022-02-16;11(4):.
    Species: Rat
    Sample Types: Whole Tissue
    Applications: IHC
  142. Paraxial mesoderm organoids model development of human somites
    Authors: C Budjan, S Liu, A Ranga, S Gayen, O Pourquié, S Hormoz
    Elife, 2022-01-28;11(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC/IF
  143. Aberrant upregulation of the glycolytic enzyme PFKFB3 in CLN7 neuronal ceroid lipofuscinosis
    Authors: I Lopez-Fabu, M Garcia-Mac, C Buondelmon, O Burmistrov, N Bonora, P Alonso-Bat, B Morant-Fer, C Vicente-Gu, D Jimenez-Bl, R Quintana-C, E Fernandez, J Llop, P Ramos-Cabr, A Sharaireh, M Guevara-Fe, L Fitzpatric, CD Thompton, TR McKay, S Storch, DL Medina, SE Mole, PO Fedichev, A Almeida, JP Bolaños
    Nature Communications, 2022-01-27;13(1):536.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  144. SOX2 mediates metabolic reprogramming of prostate cancer cells
    Authors: L de Wet, A Williams, M Gillard, S Kregel, S Lamperis, LC Gutgesell, JE Vellky, R Brown, K Conger, GP Paner, H Wang, EE Platz, AM De Marzo, P Mu, JL Coloff, RZ Szmulewitz, DJ Vander Gri
    Oncogene, 2022-01-24;0(0):.
    Species: Human
    Sample Types: Cell Lysates
    Applications: ChIP
  145. A predominant enhancer co-amplified with the SOX2 oncogene is necessary and sufficient for its expression in squamous cancer
    Authors: Y Liu, Z Wu, J Zhou, DKA Ramadurai, KL Mortenson, E Aguilera-J, Y Yan, X Yang, AM Taylor, KE Varley, J Gertz, PS Choi, AD Cherniack, X Chen, AJ Bass, SD Bailey, X Zhang
    Nature Communications, 2021-12-08;12(1):7139.
    Species: Human
    Sample Types: Cell Lysates
    Applications: ChIP
  146. Functional human gastrointestinal organoids can be engineered from three primary germ layers derived separately from pluripotent stem cells
    Authors: AK Eicher, DO Kechele, N Sundaram, HM Berns, HM Poling, LE Haines, JG Sanchez, K Kishimoto, M Krishnamur, L Han, AM Zorn, MA Helmrath, JM Wells
    Cell Stem Cell, 2021-12-01;0(0):.
    Species: Human, Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  147. Andrographolide promotes hippocampal neurogenesis and spatial memory in the APPswe/PS1deltaE9 mouse model of Alzheimer's disease
    Authors: SB Arredondo, DT Reyes, A Herrera-So, MD Mardones, NC Inestrosa, L Varela-Nal
    Scientific Reports, 2021-11-25;11(1):22904.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  148. Lineage-tracing and translatomic analysis of damage-inducible mitotic cochlear progenitors identifies candidate genes regulating regeneration
    Authors: T Udagawa, PJ Atkinson, B Milon, JM Abitbol, Y Song, M Sperber, E Huarcaya N, M Scheibinge, R Elkon, R Hertzano, AG Cheng
    PloS Biology, 2021-11-10;19(11):e3001445.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  149. Fetal growth restriction impairs hippocampal neurogenesis and cognition via Tet1 in offspring
    Authors: W Chen, N Liu, S Shen, W Zhu, J Qiao, S Chang, J Dong, M Bai, L Ma, S Wang, W Jia, X Guo, A Li, J Xi, C Jiang, J Kang
    Cell Reports, 2021-11-02;37(5):109912.
    Species: Mouse
    Sample Types: Whole Cells, Whole Tissue
    Applications: ICC, IHC
  150. Differentiation of mouse fetal lung alveolar progenitors in serum-free organotypic cultures
    Authors: K Gkatzis, P Panza, S Peruzzo, DY Stainier
    Elife, 2021-09-29;10(0):.
    Species: Mouse
    Sample Types: Organoids
    Applications: IHC
  151. Generation of an induced pluripotent stem cell line (FDCHi006-A) from a 7-year-old girl with central precocious puberty
    Authors: T Fan, J He, Y Wang, J Yu, W Sun
    Stem Cell Research, 2021-09-28;56(0):102542.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry, ICC
  152. Embryonic and Neonatal Mouse Cochleae Are Susceptible to Zika Virus Infection
    Authors: V Munnamalai, NH Sammudin, CA Young, A Thawani, RJ Kuhn, DM Fekete
    Viruses, 2021-09-14;13(9):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  153. OCT4 cooperates with distinct ATP-dependent chromatin remodelers in na�ve and primed pluripotent states in human
    Authors: X Huang, KM Park, P Gontarz, B Zhang, J Pan, Z McKenzie, LA Fischer, C Dong, S Dietmann, X Xing, PV Shliaha, J Yang, D Li, J Ding, T Lungjangwa, M Mitalipova, SA Khan, S Imsoonthor, N Jensen, T Wang, C Kadoch, R Jaenisch, J Wang, TW Theunissen
    Nature Communications, 2021-08-26;12(1):5123.
    Species: Human
    Sample Types: Cell Lysates, Whole Cells
    Applications: ICC, Western Blot
  154. A human forebrain organoid model of fragile X syndrome exhibits altered neurogenesis and highlights new treatment strategies
    Authors: Y Kang, Y Zhou, Y Li, Y Han, J Xu, W Niu, Z Li, S Liu, H Feng, W Huang, R Duan, T Xu, N Raj, F Zhang, J Dou, C Xu, H Wu, GJ Bassell, ST Warren, EG Allen, P Jin, Z Wen
    Nature Neuroscience, 2021-08-19;0(0):.
    Species: Human
    Sample Types: Organoid
    Applications: ICC
  155. Selective deletion of human leukocyte antigens protects stem cell-derived islets from immune rejection
    Authors: AV Parent, G Faleo, J Chavez, M Saxton, DI Berrios, NR Kerper, Q Tang, M Hebrok
    Cell Reports, 2021-08-17;36(7):109538.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  156. Dynamic Spatiotemporal Expression Changes in Connexins of the Developing Primate's Cochlea
    Authors: M Hosoya, M Fujioka, AY Murayama, K Ogawa, H Okano, H Ozawa
    Genes, 2021-07-16;12(7):.
    Species: Marmoset
    Sample Types: Whole Tissue
    Applications: IHC
  157. Spatiotemporal dynamics of inner ear sensory and non-sensory cells revealed by single-cell transcriptomics
    Authors: TA Jan, Y Eltawil, AH Ling, L Chen, DC Ellwanger, S Heller, AG Cheng
    Cell Reports, 2021-07-13;36(2):109358.
    Species: Mouse
    Sample Types: Whole Cells, Whole Tissue
    Applications: ICC, IHC, RNAScope
  158. Global Transcriptional Analyses of the Wnt-Induced Development of Neural Stem Cells from Human Pluripotent Stem Cells
    Authors: BC Liu, FY Liu, XY Gao, YL Chen, QQ Meng, YL Song, XH Li, SQ Bao
    International Journal of Molecular Sciences, 2021-07-12;22(14):.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  159. A human three-dimensional neural-perivascular 'assembloid' promotes astrocytic development and enables modeling of SARS-CoV-2 neuropathology
    Authors: L Wang, D Sievert, AE Clark, S Lee, H Federman, BD Gastfriend, EV Shusta, SP Palecek, AF Carlin, JG Gleeson
    Nature Medicine, 2021-07-09;0(0):.
    Species: Human
    Sample Types: Organoid
    Applications: IHC
  160. Nucleocytoplasmic transport of the RNA-binding protein CELF2 regulates neural stem cell fates
    Authors: MJ MacPherson, SL Erickson, D Kopp, P Wen, MR Aghanoori, S Kedia, KML Burns, A Vitobello, F Tran Mau-T, Q Thomas, NB Gold, W Brucker, L Amlie-Wolf, KW Gripp, O Bodamer, L Faivre, M Muona, L Menzies, J Baptista, K Guegan, A Male, XC Wei, G He, Q Long, AM Innes, G Yang
    Cell Reports, 2021-06-08;35(10):109226.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: IHC
  161. Generation of excitatory and inhibitory neurons from common progenitors via Notch signaling in the cerebellum
    Authors: T Zhang, T Liu, N Mora, J Guegan, M Bertrand, X Contreras, AH Hansen, C Streicher, M Anderle, N Danda, L Tiberi, S Hippenmeye, BA Hassan
    Cell Reports, 2021-06-08;35(10):109208.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  162. Assessment of auditory and vestibular damage in a mouse model after single and triple blast exposures
    Authors: B Mao, Y Wang, T Balasubram, R Urioste, T Wafa, TS Fitzgerald, SJ Haraczy, K Edwards-Ho, ZN Sayyid, D Wilder, VSSS Sajja, Y Wei, P Arun, I Gist, AG Cheng, JB Long, MW Kelley
    Hearing research, 2021-06-07;407(0):108292.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  163. Capicua regulates the development of adult-born neurons in the hippocampus
    Authors: B Hourigan, SD Balay, G Yee, S Sharma, Q Tan
    Scientific Reports, 2021-06-03;11(1):11725.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  164. MeCP2 controls neural stem cell fate specification through miR-199a-mediated inhibition of BMP-Smad signaling
    Authors: H Nakashima, K Tsujimura, K Irie, T Imamura, CA Trujillo, M Ishizu, M Uesaka, M Pan, H Noguchi, K Okada, K Aoyagi, T Andoh-Noda, H Okano, AR Muotri, K Nakashima
    Cell Reports, 2021-05-18;35(7):109124.
    Species: Human, Mouse
    Sample Types: Whole Cells
    Applications: ICC
  165. Neural presbycusis at ultra-high frequency in aged common marmosets and rhesus monkeys
    Authors: Sun Z, Cheng Z, Gong N et al.
    Aging (Albany NY)
  166. Establishment of an induced pluripotent stem cell line from a female domestic ferret (Mustela putorius furo) with an X chromosome instability
    Authors: S Yoshimatsu, R Murakami, M Nakajima, T Sato, H Kawasaki, H Okano
    Stem Cell Research, 2021-05-11;53(0):102385.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  167. CD109-GP130 interaction drives glioblastoma stem cell plasticity and chemoresistance through STAT3 activity
    Authors: P Filppu, JT Ramanathan, KJ Granberg, E Gucciardo, H Haapasalo, K Lehti, M Nykter, V Le Joncour, P Laakkonen
    JCI Insight, 2021-05-10;6(9):.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Co-Immunoprecipitation, Western Blot
  168. Establishing an induced pluripotent stem cell line from neonatal common marmoset fibroblasts by an all-in-one episomal vector approach
    Authors: S Yoshimatsu, E Qian, T Sato, M Yamamoto, M Ishikawa, H Okano
    Stem Cell Research, 2021-04-30;53(0):102380.
    Species: Marmoset
    Sample Types: Whole Cells
    Applications: ICC
  169. Non-viral derivation of a transgene-free induced pluripotent stem cell line from a male beagle dog
    Authors: S Yoshimatsu, K Edamura, Y Yoshii, A Iguchi, H Kondo, H Shibuya, T Sato, S Shiozawa, H Okano
    Stem Cell Research, 2021-04-29;53(0):102375.
    Species: Canine
    Sample Types: Whole Cells
    Applications: ICC
  170. Principles of signaling pathway modulation for enhancing human naive pluripotency induction
    Authors: J Bayerl, M Ayyash, T Shani, YS Manor, O Gafni, R Massarwa, Y Kalma, A Aguilera-C, M Zerbib, H Amir, D Sheban, S Geula, N Mor, L Weinberger, S Naveh Tass, V Krupalnik, B Oldak, N Livnat, S Tarazi, S Tawil, E Wildschutz, S Ashouokhi, L Lasman, V Rotter, S Hanna, D Ben-Yosef, N Novershter, S Viukov, JH Hanna
    Cell Stem Cell, 2021-04-28;0(0):.
    Species: Human, Mouse
    Sample Types: Cell Lysates, Whole Tissue
    Applications: ChIP, IHC
  171. Generation of a heterozygous GAPDH-Luciferase human ESC line (HVRDe008-A-1) for in vivo monitoring of stem cells and their differentiated progeny
    Authors: D Gerace, KR Boulanger, J Hyoje-Ryu, DA Melton
    Stem Cell Research, 2021-04-27;53(0):102371.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  172. 5-hydroxymethylcytosine is dynamically regulated during forebrain organoid development and aberrantly altered in Alzheimer's disease
    Authors: JN Kuehner, J Chen, EC Bruggeman, F Wang, Y Li, C Xu, ZT McEachin, Z Li, L Chen, CM Hales, Z Wen, J Yang, B Yao
    Cell Reports, 2021-04-27;35(4):109042.
    Species: Human
    Sample Types: Cell Lysates, Whole Cells
    Applications: Dot Blot, ICC, Western Blot
  173. Cascade diversification directs generation of neuronal diversity in the hypothalamus
    Authors: YH Zhang, M Xu, X Shi, XL Sun, W Mu, H Wu, J Wang, S Li, P Su, L Gong, M He, M Yao, QF Wu
    Cell Stem Cell, 2021-04-21;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  174. Airway basal stem cells generate distinct subpopulations of PNECs
    Authors: H Mou, Y Yang, MA Riehs, J Barrios, M Shivaraju, AL Haber, DT Montoro, K Gilmore, EA Haas, B Paunovic, J Rajagopal, SO Vargas, RL Haynes, A Fine, WV Cardoso, X Ai
    Cell Reports, 2021-04-20;35(3):109011.
    Species: Human
    Sample Types: Whole Cells, Whole Tissue
    Applications: ICC, IHC
  175. Hypothalamic Rax+ tanycytes contribute to tissue repair and tumorigenesis upon oncogene activation in mice
    Authors: W Mu, S Li, J Xu, X Guo, H Wu, Z Chen, L Qiao, G Helfer, F Lu, C Liu, QF Wu
    Nature Communications, 2021-04-16;12(1):2288.
    Species: Mouse
    Sample Types: Cell Lysates, Whole Tissue
    Applications: IHC, Western Blot
  176. Organoid modeling of Zika and herpes simplex virus 1 infections reveals virus-specific responses leading to microcephaly
    Authors: V Krenn, C Bosone, TR Burkard, J Spanier, U Kalinke, A Calistri, C Salata, R Rilo Chris, P Pestana Ga, A Mirazimi, JA Knoblich
    Cell Stem Cell, 2021-04-09;0(0):.
    Species: Human
    Sample Types: Organoid
    Applications: IHC
  177. An induced pluripotent stem cell line (GZHMCi004-A) derived from a fetus with heterozygous G380R mutation in FGFR3 gene causing achondroplasia
    Authors: N Li, SM Lin, Y Li, J Sun, L Zhang, M Chen
    Stem Cell Research, 2021-04-05;53(0):102322.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry, ICC
  178. Ogt controls neural stem/progenitor cell pool and adult neurogenesis through modulating Notch signaling
    Authors: J Chen, X Dong, X Cheng, Q Zhu, J Zhang, Q Li, X Huang, M Wang, L Li, W Guo, B Sun, Q Shu, W Yi, X Li
    Cell Reports, 2021-03-30;34(13):108905.
    Species: Mouse
    Sample Types: Cell Lysates, Whole Cells, Whole Tissue
    Applications: ICC, IHC, Immunoprecipitation, Western Blot
  179. Generation of a common marmoset embryonic stem cell line CMES40-OC harboring a POU5F1 (OCT4)-2A-mCerulean3 knock-in reporter allele
    Authors: S Yoshimatsu, R Murakami, T Sato, T Saeki, M Yamamoto, E Sasaki, T Noce, H Okano
    Stem Cell Research, 2021-03-24;53(0):102308.
    Species: Primate - Callithrix jacchus (Common Marmoset)
    Sample Types: Whole Cells
    Applications: Immunocytochemistry
  180. Evaluation of UBE3A antibodies in mice and human cerebral organoids
    Authors: D Sen, Z Drobna, AJ Keung
    Scientific Reports, 2021-03-18;11(1):6323.
    Species: Mouse
    Sample Types: Cell Lysates, Whole Tissue
    Applications: IHC, Western Blot
  181. Transcriptional networks identify synaptotagmin-like 3 as a regulator of cortical neuronal migration during early neurodevelopment
    Authors: X Dong, L Yang, K Liu, X Ji, C Tang, W Li, L Ma, Y Mei, T Peng, B Feng, Z Wu, Q Tang, Y Gao, K Yan, W Zhou, M Xiong
    Cell Reports, 2021-03-02;34(9):108802.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  182. Autologous transplant therapy alleviates motor and depressive behaviors in parkinsonian monkeys
    Authors: Y Tao, SC Vermilyea, M Zammit, J Lu, M Olsen, JM Metzger, L Yao, Y Chen, S Phillips, JE Holden, V Bondarenko, WF Block, TE Barnhart, N Schultz-Da, K Brunner, H Simmons, BT Christian, ME Emborg, SC Zhang
    Nature Medicine, 2021-03-01;0(0):.
    Species: Primate - Rhesus macaque
    Sample Types: Whole Cells, Whole Tissue
    Applications: ICC, IHC
  183. Differentiated glioblastoma cells accelerate tumor progression by shaping the tumor microenvironment via CCN1-mediated macrophage infiltration
    Authors: A Uneda, K Kurozumi, A Fujimura, K Fujii, J Ishida, Y Shimazu, Y Otani, Y Tomita, Y Hattori, Y Matsumoto, N Tsuboi, K Makino, S Hirano, A Kamiya, I Date
    Acta neuropathologica communications, 2021-02-22;9(1):29.
    Species: Human, Mouse
    Sample Types: Cell Lysates, Whole Tissue
    Applications: IHC, Western Blot
  184. Generation of a gene-corrected isogenic iPSC line (AHQUi001-A-1) from a patient with familial hypertriglyceridemia (FHTG) carrying a heterozygous p.C310R (c.928�T�>�C) mutation in LPL gene using CRISPR/Cas9
    Authors: X Sun, X Zhou, B Dong, C Wang, X Xiao, Y Wang
    Stem Cell Research, 2021-02-11;52(0):102230.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry, ICC
  185. Greater epithelial ridge cells are the principal organoid-forming progenitors of the mouse cochlea
    Authors: M Kubota, M Scheibinge, TA Jan, S Heller
    Cell Reports, 2021-01-19;34(3):108646.
    Species: Mouse
    Sample Types: Organoid
    Applications: IHC
  186. An induced pluripotent stem cell line (GZHMCi003-A) derived from a fetus with exon 3 heterozygous deletion in RUNX2 gene causing cleidocranial dysplasia
    Authors: M Chen, SM Lin, N Li, Y Li, Y Li, L Zhang
    Stem Cell Research, 2021-01-09;51(0):102166.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry, ICC
  187. Generation and validation of a common marmoset embryonic stem cell line ActiCre-B1 that ubiquitously expresses a tamoxifen-inducible Cre-driver
    Authors: S Yoshimatsu, K Ohtsu, T Sato, M Yamamoto, E Sasaki, S Shiozawa, H Okano
    Stem Cell Research, 2021-01-08;51(0):102164.
    Species: Marmoset
    Sample Types: Whole Cells
    Applications: Flow Cytometry, ICC
  188. ApoE-Isoform-Dependent SARS-CoV-2 Neurotropism and Cellular Response
    Authors: C Wang, M Zhang, G Garcia, E Tian, Q Cui, X Chen, G Sun, J Wang, V Arumugaswa, Y Shi
    Cell Stem Cell, 2021-01-04;28(2):331-342.e5.
    Species: Human
    Sample Types: Organoid
    Applications: ICC
  189. Reconstruction of Alzheimer's Disease Cell Model In Vitro via Extracted Peripheral Blood Molecular Cells from a Sporadic Patient
    Authors: S Liu, Y Zhao, X Su, C Zhou, P Yang, Q Lin, S Li, H Tan, Q Wang, C Wang, Q Wu
    Stem Cells International, 2020-12-18;2020(0):8897494.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  190. WAPL maintains a cohesin loading cycle to preserve cell-type-specific distal gene regulation
    Authors: NQ Liu, M Maresca, T van den Br, L Braccioli, MMGA Schijns, H Teunissen, BG Bruneau, EP Nora, E de Wit
    Nature Genetics, 2020-12-14;0(0):.
    Species: Human
    Sample Types: Cell Lysates
    Applications: ChIP
  191. Multiscale 3D phenotyping of human cerebral organoids
    Authors: A Albanese, JM Swaney, DH Yun, NB Evans, JM Antonucci, S Velasco, CH Sohn, P Arlotta, L Gehrke, K Chung
    Scientific Reports, 2020-12-08;10(1):21487.
    Species: Aedes albopictus (mosquito)
    Sample Types: Organoid
    Applications: ICC
  192. ROBO2 signaling in lung development regulates SOX2/SOX9 balance, branching morphogenesis and is dysregulated in nitrofen-induced congenital diaphragmatic hernia
    Authors: AN Gonçalves, J Correia-Pi, C Nogueira-S
    Respir Res, 2020-11-18;21(1):302.
    Species: Rat
    Sample Types: Cell Lysates
    Applications: Western Blot
  193. SATB2 drives glioblastoma growth by recruiting CBP to promote FOXM1 expression in glioma stem cells
    Authors: W Tao, A Zhang, K Zhai, Z Huang, H Huang, W Zhou, Q Huang, X Fang, BC Prager, X Wang, Q Wu, AE Sloan, MS Ahluwalia, JD Lathia, JS Yu, JN Rich, S Bao
    EMBO Mol Med, 2020-10-30;0(0):e12291.
    Species: Human, Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  194. Human Lung Stem Cell-Based Alveolospheres Provide Insights into SARS-CoV-2-Mediated Interferon Responses and Pneumocyte Dysfunction
    Authors: H Katsura, V Sontake, A Tata, Y Kobayashi, CE Edwards, BE Heaton, A Konkimalla, T Asakura, Y Mikami, EJ Fritch, PJ Lee, NS Heaton, RC Boucher, SH Randell, RS Baric, PR Tata
    Cell Stem Cell, 2020-10-21;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  195. LRIG1-Mediated Inhibition of EGF Receptor Signaling Regulates Neural Precursor Cell Proliferation in the Neocortex
    Authors: D Jeong, D Lozano Cas, A Gengathara, K Edwards, A Saghatelya, DR Kaplan, FD Miller, SA Yuzwa
    Cell Rep, 2020-10-13;33(2):108257.
    Species: Mouse
    Sample Types: Whole Cells, Whole Tissue
    Applications: ICC, IHC
  196. TAZ Represses the Neuronal Commitment of Neural Stem Cells
    Authors: N Robledinos, M Escoll, KL Guan, A Cuadrado
    Cells, 2020-10-02;9(10):.
    Species: Mouse
    Sample Types: Cell Lysates, Whole Tissue
    Applications: IHC, Western Blot
  197. Establishment of human induced pluripotent stem cell line (CPGHi002-A) from a 10-month-old female patient with DDOD syndrome carrying a heterozygous c.1516 C�>�T mutation in ATP6V1B2
    Authors: X Gao, SW Qiu, ML Feng, SS Huang, DY Kang, MY Han, P Dai, YY Yuan
    Stem Cell Res, 2020-09-08;48(0):101986.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  198. Mapping the Effects of Genetic Variation on Chromatin State and Gene Expression Reveals Loci That Control Ground State Pluripotency
    Authors: DA Skelly, A Czechanski, C Byers, S Aydin, C Spruce, C Olivier, K Choi, DM Gatti, N Raghupathy, GR Keele, A Stanton, M Vincent, S Dion, I Greenstein, M Pankratz, DK Porter, W Martin, C O'Connor, W Qin, AH Harrill, T Choi, GA Churchill, SC Munger, CL Baker, LG Reinholdt
    Cell Stem Cell, 2020-08-13;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC, IHC
  199. Efficient in Utero Gene Transfer to the Mammalian Inner Ears by the Synthetic Adeno-Associated Viral Vector Anc80L65
    Authors: CJ Hu, YC Lu, YH Tsai, HY Cheng, H Takeda, CY Huang, R Xiao, CJ Hsu, JW Tsai, LH Vandenberg, CC Wu, YF Cheng
    Mol Ther Methods Clin Dev, 2020-06-24;18(0):493-500.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  200. Variation of Human Neural Stem Cells Generating Organizer States In�Vitro before Committing to Cortical Excitatory or Inhibitory Neuronal Fates
    Authors: N Micali, SK Kim, M Diaz-Busta, G Stein-O'Br, S Seo, JH Shin, BG Rash, S Ma, Y Wang, NA Olivares, JI Arellano, KR Maynard, EJ Fertig, AJ Cross, RW Bürli, NJ Brandon, DR Weinberger, JG Chenoweth, DJ Hoeppner, N Sestan, P Rakic, C Colantuoni, RD McKay
    Cell Rep, 2020-05-05;31(5):107599.
    Species: Human
    Sample Types:
    Applications: IF
  201. Generation of an iPSC line (CHWi001-A) from peripheral blood mononuclear cells in a patient with intellectual disability and haploinsufficiency of PLPPR4
    Authors: R Wan, Q Zhang, H Li, X Xu, S Tang
    Stem Cell Res, 2020-05-01;45(0):101811.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  202. Medulloblastoma Arises from the Persistence of a Rare and Transient Sox2+ Granule Neuron Precursor
    Authors: HJ Selvadurai, E Luis, K Desai, X Lan, MC Vladoiu, O Whitley, C Galvin, RJ Vanner, L Lee, H Whetstone, M Kushida, T Nowakowski, P Diamandis, C Hawkins, G Bader, A Kriegstein, MD Taylor, PB Dirks
    Cell Rep, 2020-04-14;31(2):107511.
    Species: Mouse
    Sample Types: Embryo
    Applications: IF
  203. Cdk4 and Cdk6 Couple the Cell-Cycle Machinery to Cell Growth via mTORC1
    Authors: J Romero-Poz, G Figlia, O Kaya, A Martin-Vil, AA Teleman
    Cell Rep, 2020-04-14;31(2):107504.
    Species: Mouse
    Sample Types: Neural Stem Cells
    Applications: IF
  204. Generation of an induced pluripotent stem cell line (DANi-011A) from a Parkinson's disease patient with a LRRK2 p.G2019S mutation
    Authors: M Chen, M Maimaitili, SH Buchholdt, UB Jensen, F Febbraro, M Denham
    Stem Cell Res, 2020-03-29;45(0):101781.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  205. Glycolysis-Independent Glucose Metabolism Distinguishes TE from ICM Fate during Mammalian Embryogenesis.
    Authors: Chi F, Sharpley M, Nagaraj R et al.
    Dev Cell.
  206. Identification of ALPPL2 as a Naive Pluripotent State-Specific Surface Protein Essential for Human Naive Pluripotency Regulation
    Authors: Y Bi, Z Tu, Y Zhang, P Yang, M Guo, X Zhu, C Zhao, J Zhou, H Wang, Y Wang, S Gao
    Cell Rep, 2020-03-17;30(11):3917-3931.e5.
    Species: Human
    Sample Types: Cell Lysates, Whole Cells
    Applications: Flow Cytometry, ICC, Western Blot
  207. Generation of an isogenic gene-corrected iPSC line (PUMCHi001-A-1) from a familial partial lipodystrophy type 2 (FPLD2) patient with a heterozygous R349W mutation in the LMNA gene
    Authors: C Xiao, M Yu, J Liu, H Wu, M Deng, Q Zhang, X Xiao
    Stem Cell Res, 2020-03-14;44(0):101753.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  208. Lysine acetyltransferase 8 is involved in cerebral development and syndromic intellectual disability
    Authors: L Li, M Ghorbani, M Weisz-Hubs, J Rousseau, I Thiffault, RE Schnur, C Breen, R Oegema, MM Weiss, Q Waisfisz, S Welner, H Kingston, JA Hills, EM Boon, L Basel-Salm, O Konen, H Goldberg-S, L Bazak, S Tzur, J Jin, X Bi, M Bruccoleri, K McWalter, MT Cho, M Scarano, GB Schaefer, SS Brooks, SS Hughes, KLI van Gassen, JM van Hagen, TK Pandita, PB Agrawal, PM Campeau, XJ Yang
    J. Clin. Invest., 2020-03-02;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  209. Generation of a male common marmoset embryonic stem cell line DSY127-BV8VT1 carrying double reporters specific for the germ cell linage using the CRISPR-Cas9 and PiggyBac transposase systems
    Authors: S Yoshimatsu, T Sato, M Yamamoto, E Sasaki, M Nakajima, M Nakamura, S Shiozawa, T Noce, H Okano
    Stem Cell Res, 2020-02-21;44(0):101740.
    Species: Callithrix jacchus (Marmoset)
    Sample Types: Whole Cells
    Applications: ICC
  210. An induced pluripotent stem cell line (SHEHi002-A (5426))from a patient of long QT syndrome type 8 with c.2573G>A mutation in the gene CACNA1C
    Authors: HM Zhou, XQ Zhou, JZ Lu, WW Jia, JH Kang
    Stem Cell Res, 2020-02-06;43(0):101731.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  211. Lumen Expansion Facilitates Epiblast-Primitive Endoderm Fate Specification during Mouse Blastocyst Formation
    Authors: Allyson Quinn Ryan, Chii Jou Chan, François Graner, Takashi Hiiragi
    Developmental Cell
  212. Lumen Expansion Facilitates Epiblast-Primitive Endoderm Fate Specification during Mouse Blastocyst Formation
    Authors: Allyson Quinn Ryan, Chii Jou Chan, François Graner, Takashi Hiiragi
    Developmental Cell
  213. Gastrointestinal transcription factors drive lineage-specific developmental programs in organ specification and cancer
    Authors: R Francis, H Guo, C Streutker, M Ahmed, T Yung, PB Dirks, HH He, TH Kim
    Sci Adv, 2019-12-11;5(12):eaax8898.
    Species: Mouse
    Sample Types: Cell Lysates
    Applications: ChIP
  214. Establishment of induced pluripotent stem cell line (GSPHi001-A) from a 6-year old female with nephrotic syndrome
    Authors: X Gao, X Gao, H Zhao, W Cui, M Tan, H Deng
    Stem Cell Res, 2019-11-15;41(0):101661.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  215. Lack of whey acidic protein four disulphide core (WFDC) 2 protease inhibitor causes neonatal death from respiratory failure in mice
    Authors: K Nakajima, M Ono, U Radovi?, S Dizdarevi?, SI Tomizawa, K Kuroha, G Naganatsu, I Hoshi, R Matsunaga, T Shirakawa, T Kurosawa, Y Miyazaki, M Seki, Y Suzuki, H Koseki, M Nakamura, T Suda, K Ohbo
    Dis Model Mech, 2019-11-12;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  216. The RNA Helicase DDX6 Controls Cellular Plasticity by Modulating P-Body Homeostasis
    Authors: B Di Stefano, EC Luo, C Haggerty, S Aigner, J Charlton, J Brumbaugh, F Ji, I Rabano Jim, KJ Clowers, AJ Huebner, K Clement, I Lipchina, MAC de Kort, A Anselmo, J Pulice, MFM Gerli, H Gu, SP Gygi, RI Sadreyev, A Meissner, GW Yeo, K Hochedling
    Cell Stem Cell, 2019-10-03;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  217. Epigenomic Profiling Discovers Trans-lineage SOX2 Partnerships Driving Tumor Heterogeneity in Lung Squamous Cell Carcinoma
    Authors: T Sato, S Yoo, R Kong, A Sinha, P Chandraman, A Patel, M Fridrikh, O Nagano, T Masuko, MB Beasley, CA Powell, J Zhu, H Watanabe
    Cancer Res., 2019-09-24;79(24):6084-6100.
    Species: Human
    Sample Types: Cell Lysates
    Applications: ChIP, Western Blot
  218. Biomanufacturing of organ-specific tissues with high cellular density and embedded vascular channels
    Authors: MA Skylar-Sco, SGM Uzel, LL Nam, JH Ahrens, RL Truby, S Damaraju, JA Lewis
    Sci Adv, 2019-09-06;5(9):eaaw2459.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  219. Single-cell analysis reveals T cell infiltration in old neurogenic niches
    Authors: BW Dulken, MT Buckley, P Navarro Ne, N Saligrama, R Cayrol, DS Leeman, BM George, SC Boutet, K Hebestreit, JV Pluvinage, T Wyss-Coray, IL Weissman, H Vogel, MM Davis, A Brunet
    Nature, 2019-07-03;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  220. Semaphorin-5B Controls Spiral Ganglion Neuron Branch Refinement During Development
    Authors: JS Jung, KD Zhang, Z Wang, M McMurray, A Tkaczuk, Y Ogawa, R Hertzano, TM Coate
    J. Neurosci., 2019-06-17;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  221. Hydraulic control of mammalian embryo size and cell fate
    Authors: CJ Chan, M Costanzo, T Ruiz-Herre, G Mönke, RJ Petrie, M Bergert, A Diz-Muñoz, L Mahadevan, T Hiiragi
    Nature, 2019-06-12;0(0):.
    Species: Mouse
    Sample Types: Embryo
    Applications: IHC
  222. Direct Reprogramming of Human Neurons Identifies MARCKSL1 as a Pathogenic Mediator of Valproic Acid-Induced Teratogenicity
    Authors: S Chanda, CE Ang, QY Lee, M Ghebrial, D Haag, Y Shibuya, M Wernig, TC Südhof
    Cell Stem Cell, 2019-05-30;25(1):103-119.e6.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  223. YAP Activity Is Necessary and Sufficient for Basal Progenitor Abundance and Proliferation in the Developing Neocortex
    Authors: M Kostic, JTML Paridaen, KR Long, N Kalebic, B Langen, N Grübling, P Wimberger, H Kawasaki, T Namba, WB Huttner
    Cell Rep, 2019-04-23;27(4):1103-1118.e6.
    Species: Ferret, Human, Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  224. Zika virus infection induces RNAi-mediated antiviral immunity in human neural progenitors and brain organoids
    Authors: YP Xu, Y Qiu, B Zhang, G Chen, Q Chen, M Wang, F Mo, J Xu, J Wu, RR Zhang, ML Cheng, NN Zhang, B Lyu, WL Zhu, MH Wu, Q Ye, D Zhang, JH Man, XF Li, J Cui, Z Xu, B Hu, X Zhou, CF Qin
    Cell Res., 2019-02-27;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  225. O-GlcNAc transferase activates stem-like cell potential in hepatocarcinoma through O-GlcNAcylation of eukaryotic initiation factor 4E
    Authors: B Cao, M Duan, Y Xing, C Liu, F Yang, Y Li, T Yang, Y Wei, Q Gao, J Jiang
    J. Cell. Mol. Med., 2019-01-24;0(0):.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  226. Chi3l3 induces oligodendrogenesis in an experimental model of autoimmune neuroinflammation
    Authors: SC Starossom, J Campo Garc, T Woelfle, S Romero-Sua, M Olah, F Watanabe, L Cao, A Yeste, JJ Tukker, FJ Quintana, J Imitola, F Witzel, D Schmitz, M Morkel, F Paul, C Infante-Du, SJ Khoury
    Nat Commun, 2019-01-15;10(1):217.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  227. The BAF and PRC2 Complex Subunits Dpf2 and Eed Antagonistically Converge on Tbx3 to Control ESC Differentiation
    Authors: W Zhang, C Chronis, X Chen, H Zhang, R Spalinskas, M Pardo, L Chen, G Wu, Z Zhu, Y Yu, L Yu, J Choudhary, J Nichols, MM Parast, B Greber, P Sahlén, K Plath
    Cell Stem Cell, 2019-01-03;24(1):138-152.e8.
    Species: Mouse
    Sample Types: Cell Lysates
    Applications: Western Blot
  228. Generation of seven induced pluripotent stem cell lines from neonates of different ethnic backgrounds
    Authors: Y Yin, AJ Petersen, C Soref, WD Richards, T Ludwig, S Taapken, E Berndt, SC Zhang, A Bhattachar
    Stem Cell Res, 2018-12-20;34(0):101365.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  229. Generation of Spinocerebellar Ataxia Type 2 induced pluripotent stem cell lines, CHOPi002-A and CHOPi003-A, from patients with abnormal CAG repeats in the coding region of the ATXN2 gene
    Authors: JA Maguire, AL Gagne, P Gonzalez-A, BL Davidson, V Shakkottai, P Gadue, DL French
    Stem Cell Res, 2018-12-10;34(0):101361.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  230. Transcriptional repressor GATA binding 1-mediated repression of SRY-box 2 expression suppresses cancer stem cell functions and tumor initiation
    Authors: X Gong, W Liu, L Wu, Z Ma, Y Wang, S Yu, J Zhang, H Xie, G Wei, F Ma, L Lu, L Chen
    J. Biol. Chem., 2018-10-12;0(0):.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  231. Treatment of Human Glioblastoma with a Live Attenuated Zika Virus Vaccine Candidate
    Authors: Q Chen, J Wu, Q Ye, F Ma, Q Zhu, Y Wu, C Shan, X Xie, D Li, X Zhan, C Li, XF Li, X Qin, T Zhao, H Wu, PY Shi, J Man, CF Qin
    MBio, 2018-09-18;9(5):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  232. Injectable polypeptide hydrogels via methionine modification for neural stem cell delivery
    Authors: Wollenberg AL, O'Shea TM, Kim JH et al.
    Biomaterials
  233. BCL11A interacts with SOX2 to control the expression of epigenetic regulators in lung squamous carcinoma
    Authors: KA Lazarus, F Hadi, E Zambon, K Bach, MF Santolla, JK Watson, LL Correia, M Das, R Ugur, S Pensa, L Becker, LS Campos, G Ladds, P Liu, GI Evan, FM McCaughan, J Le Quesne, JH Lee, D Calado, WT Khaled
    Nat Commun, 2018-08-20;9(1):3327.
    Species: Human
    Sample Types: DNA
    Applications: ChIP
  234. Selective enrichment of CD133+/SOX2+ glioblastoma stem cells via adherent culture
    Authors: K Lv, Z Chen, X Zhang, Q Zhang, L Liu
    Oncol Lett, 2018-07-17;16(4):4567-4576.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  235. Generation of a human Juvenile myelomonocytic leukemia iPSC line, CHOPi001-A, with a mutation in CBL
    Authors: AL Gagne, JA Maguire, S Gandre-Bab, ST Chou, SK Tasian, ML Loh, MJ Weiss, P Gadue, DL French
    Stem Cell Res, 2018-07-05;31(0):157-160.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  236. SNAI2 upregulation is associated with an aggressive phenotype in fulvestrant-resistant breast cancer cells and is an indicator of poor response to endocrine therapy in estrogen receptor-positive metastatic breast cancer
    Authors: CL Alves, D Elias, MB Lyng, M Bak, HJ Ditzel
    Breast Cancer Res., 2018-06-19;20(1):60.
    Species: Human
    Sample Types: Cell Lysates, Whole Cells
    Applications: ICC, Western Blot
  237. BMP and WNT signalling cooperate through LEF1 in the neuronal specification of adult hippocampal neural stem and progenitor cells
    Authors: T Armenteros, Z Andreu, R Hortigüela, DC Lie, H Mira
    Sci Rep, 2018-06-18;8(1):9241.
    Species: Rat
    Sample Types: Whole Cells
    Applications: ICC
  238. NMDA receptor signaling is important for neural tube formation and for preventing antiepileptic drug-induced neural tube defects
    Authors: EB Sequerra, R Goyal, PA Castro, JB Levin, LN Borodinsky
    J. Neurosci., 2018-04-30;0(0):.
    Species: Xenopus
    Sample Types: Whole Tissue
    Applications: IHC
  239. Submucosal Gland Myoepithelial Cells Are Reserve Stem Cells That Can Regenerate Mouse Tracheal Epithelium
    Authors: TJ Lynch, PJ Anderson, PG Rotti, SR Tyler, AK Crooke, SH Choi, DT Montoro, CL Silverman, W Shahin, R Zhao, CW Jensen-Cod, A Adamcakova, TIA Evans, W Xie, Y Zhang, H Mou, BP Herring, PS Thorne, J Rajagopal, C Yeaman, KR Parekh, JF Engelhardt
    Cell Stem Cell, 2018-04-12;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  240. Developmental History Provides a Roadmap for the Emergence of Tumor Plasticity
    Authors: PR Tata, RD Chow, SV Saladi, A Tata, A Konkimalla, A Bara, D Montoro, LP Hariri, AR Shih, M Mino-Kenud, H Mou, S Kimura, LW Ellisen, J Rajagopal
    Dev. Cell, 2018-03-26;44(6):679-693.e5.
    Species: Human, Mouse
    Sample Types: Cell Lysates, Whole Tissue
    Applications: IHC-Fr, Western Blot
  241. Complementary expression of calcium binding proteins delineates the functional organization of the locomotor network
    Authors: EM Berg, M Bertuzzi, K Ampatzis
    Brain Struct Funct, 2018-02-08;0(0):.
    Species: Zebrafish
    Sample Types: Whole Tissue
    Applications: IHC
  242. Central and Peripheral Nervous System Progenitors Derived from Human Pluripotent Stem Cells Reveal a Unique Temporal and Cell-Type Specific Expression of PMCAs
    Authors: M Chen, SH Laursen, M Habekost, CH Knudsen, SH Buchholdt, J Huang, F Xu, X Liu, L Bolund, Y Luo, P Nissen, F Febbraro, M Denham
    Front Cell Dev Biol, 2018-02-06;6(0):5.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  243. NADsupplementation normalizes key Alzheimer's features and DNA damage responses in a new AD mouse model with introduced DNA repair deficiency
    Authors: Y Hou, S Lautrup, S Cordonnier, Y Wang, DL Croteau, E Zavala, Y Zhang, K Moritoh, JF O'Connell, BA Baptiste, TV Stevnsner, MP Mattson, VA Bohr
    Proc. Natl. Acad. Sci. U.S.A., 2018-02-05;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  244. Synaptic regulator ?-synuclein in dopaminergic fibers is essentially required for the maintenance of subependymal neural stem cells
    Authors: A Perez-Vill, M Salomé Sir, G Belenguer, R Soriano-Ca, A Belén Muño, J Villadiego, D Alarcón-Ar, FN Soria, B Dehay, E Bezard, M Vila, A Bortolozzi, J José Toled, F Pérez-Sánc, I Fariñas
    J. Neurosci., 2017-12-07;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  245. Directed transdifferentiation of M�ller glial cells to photoreceptors using the sonic hedgehog signaling pathway agonist purmorphamine
    Authors: D Gu, S Wang, S Zhang, P Zhang, G Zhou
    Mol Med Rep, 2017-09-28;0(0):.
    Species: Rat
    Sample Types: Whole Cells
    Applications: ICC
  246. Peptide-Based Scaffolds Support Human Cortical Progenitor Graft Integration to Reduce Atrophy and Promote Functional Repair in a Model of Stroke
    Authors: FA Somaa, TY Wang, JC Niclis, KF Bruggeman, JA Kauhausen, H Guo, S McDougall, RJ Williams, DR Nisbet, LH Thompson, CL Parish
    Cell Rep, 2017-08-22;20(8):1964-1977.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  247. Reduced expression of the murine HLA-G homolog Qa-2 is associated with malignancy, epithelial-mesenchymal transition and stemness in breast cancer cells
    Authors: IL da Silva, L Montero-Mo, E Martín-Vil, J Martin-Pér, B Sainz, J Renart, R Toscano Si, É Soares Vel, C Salviano T, MC de Oliveir, E Ferreira, M Quintanill
    Sci Rep, 2017-07-24;7(1):6276.
    Species: Mouse
    Sample Types: Cell Lysates
    Applications: Western Blot
  248. Succession of transiently active tumor-initiating cell clones in human pancreatic cancer xenografts
    Authors: CR Ball, F Oppel, KR Ehrenberg, TD Dubash, SM Dieter, CM Hoffmann, U Abel, F Herbst, M Koch, J Werner, F Bergmann, N Ishaque, M Schmidt, C von Kalle, C Scholl, S Fröhling, B Brors, W Weichert, J Weitz, H Glimm
    EMBO Mol Med, 2017-07-01;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  249. Sin3a regulates epithelial progenitor cell fate during lung development
    Authors: C Yao, G Carraro, B Konda, X Guan, T Mizuno, N Chiba, M Kostelny, A Kurkciyan, G David, JL McQualter, BR Stripp
    Development, 2017-06-15;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  250. CryoPause: A New Method to Immediately Initiate Experiments after Cryopreservation of Pluripotent Stem Cells
    Authors: KG Wong, SD Ryan, K Ramnarine, SA Rosen, SE Mann, A Kulick, E De Stanchi, FJ Müller, TJ Kacmarczyk, C Zhang, D Betel, MJ Tomishima
    Stem Cell Reports, 2017-06-08;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  251. Colitis promotes neuronal differentiation of Sox2+ and PLP1+ enteric cells
    Authors: J Belkind-Ge, HK Graham, J Reynolds, R Hotta, N Nagy, L Cheng, M Kamionek, HN Shi, CM Aherne, AM Goldstein
    Sci Rep, 2017-05-31;7(1):2525.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  252. Sox2 regulates M�ller glia reprogramming and proliferation in the regenerating zebrafish retina via Lin28 and Ascl1a
    Authors: RA Gorsuch, M Lahne, CE Yarka, ME Petravick, J Li, DR Hyde
    Exp. Eye Res., 2017-05-31;0(0):.
    Species: Fish
    Sample Types: Whole Tissue
    Applications: IHC
  253. Generation of a multipurpose Prdm16 allele by targeted trapping
    Authors: A Strassman, F Schnütgen, Q Dai, JC Jones, AC Gomez, L Pitstick, NE Holton, R Moskal, ER Leslie, H von Melchn, DR Beier, BC Bjork
    Dis Model Mech, 2017-04-19;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  254. Folate receptor alpha is necessary for neural plate cell apical constriction during Xenopus neural tube formation
    Authors: OA Balashova, O Visina, LN Borodinsky
    Development, 2017-03-02;0(0):.
    Species: Xenopus
    Sample Types: Whole Tissue
    Applications: IHC-P
  255. Long-Distance Axonal Growth and Protracted Functional Maturation of Neurons Derived From Human Induced Pluripotent Stem Cells After Intracerebral Transplantation
    Authors: JC Niclis, C Turner, J Durnall, S McDougal, JA Kauhausen, B Leaw, M Dottori, CL Parish, LH Thompson
    Stem Cells Transl Med, 2017-02-15;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  256. Evidence of functional duplicity of Nestin expression in the adult mouse midbrain
    Authors: P Farzanehfa, SS Lu, A Dey, D Musiienko, H Baagil, MK Horne, TD Aumann
    Stem Cell Res, 2017-01-05;19(0):82-93.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  257. Human neural progenitors derived from integration-free iPSCs for SCI therapy
    Authors: Y Liu, Y Zheng, S Li, H Xue, K Schmitt, GW Hergenroed, J Wu, Y Zhang, DH Kim, Q Cao
    Stem Cell Res, 2017-01-05;19(0):55-64.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  258. Patient-Specific Screening Using High-Grade Glioma Explants to Determine Potential Radiosensitization by a TGF-? Small Molecule Inhibitor
    Neoplasia, 2016-12-01;18(12):795-805.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  259. SOX2 and PI3K Cooperate to Induce and Stabilize a Squamous-Committed Stem Cell Injury State during Lung Squamous Cell Carcinoma Pathogenesis
    PLoS Biol., 2016-11-23;14(11):e1002581.
    Species: Human
    Sample Types: Whole Cells
    Applications: IHC-P
  260. Traumatic Brain Injury Stimulates Neural Stem Cell Proliferation via Mammalian Target of Rapamycin Signaling Pathway Activation
    Authors: Jinhui Chen
    eNeuro, 2016-11-01;3(5):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  261. An essential role of SVZ progenitors in cortical folding in gyrencephalic mammals
    Sci Rep, 2016-07-12;6(0):29578.
    Species: Ferret
    Sample Types: Whole Tissue
    Applications: IHC
  262. RBPJ maintains brain tumor-initiating cells through CDK9-mediated transcriptional elongation
    Authors: Qi Xie
    J Clin Invest, 2016-06-20;126(7):2757-2772.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  263. Inversion of Sonic hedgehog action on its canonical pathway by electrical activity.
    Authors: Belgacem Y, Borodinsky L
    Proc Natl Acad Sci U S A, 2015-03-17;112(13):4140-5.
    Species: Xenopus
    Sample Types: Embryo
    Applications: IHC-P
  264. The chromatin regulator Brpf1 regulates embryo development and cell proliferation.
    Authors: You L, Yan K, Zou J, Zhao H, Bertos N, Park M, Wang E, Yang X
    J Biol Chem, 2015-03-15;290(18):11349-64.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  265. Mitochondrial control by DRP1 in brain tumor initiating cells.
    Authors: Xie Q, Wu Q, Horbinski C, Flavahan W, Yang K, Zhou W, Dombrowski S, Huang Z, Fang X, Shi Y, Ferguson A, Kashatus D, Bao S, Rich J
    Nat Neurosci, 2015-03-02;18(4):501-10.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  266. Acellular lung scaffolds direct differentiation of endoderm to functional airway epithelial cells: requirement of matrix-bound HS proteoglycans.
    Authors: Shojaie S, Ermini L, Ackerley C, Wang J, Chin S, Yeganeh B, Bilodeau M, Sambi M, Rogers I, Rossant J, Bear C, Post M
    Stem Cell Reports, 2015-02-05;4(3):419-30.
    Species: Mouse, Rat
    Sample Types: Whole Cells
    Applications: IHC
  267. Angiogenesis in the developing spinal cord: blood vessel exclusion from neural progenitor region is mediated by VEGF and its antagonists.
    Authors: Takahashi, Teruaki, Takase, Yuta, Yoshino, Takashi, Saito, Daisuke, Tadokoro, Ryosuke, Takahashi, Yoshiko
    PLoS ONE, 2015-01-13;10(1):e0116119.
    Species: Avian - Quail, Chicken
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  268. Deficiency of the chromatin regulator BRPF1 causes abnormal brain development.
    Authors: You L, Zou J, Zhao H, Bertos N, Park M, Wang E, Yang X
    J Biol Chem, 2015-01-07;290(11):7114-29.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  269. Selective lentiviral gene delivery to CD133-expressing human glioblastoma stem cells.
    Authors: Bayin, N Sumru, Modrek, Aram S, Dietrich, August, Lebowitz, Jonathan, Abel, Tobias, Song, Hae-Ri, Schober, Markus, Zagzag, David, Buchholz, Christia, Chao, Moses V, Placantonakis, Dimitris
    PLoS ONE, 2014-12-26;9(12):e116114.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  270. 3D imaging of Sox2 enhancer clusters in embryonic stem cells.
    Authors: Liu, Zhe, Legant, Wesley R, Chen, Bi-Chang, Li, Li, Grimm, Jonathan, Lavis, Luke D, Betzig, Eric, Tjian, Robert
    Elife, 2014-12-24;3(0):e04236.
    Species: Mouse
    Sample Types: Cell Lysates
    Applications: ChIP
  271. Increased cycling cell numbers and stem cell associated proteins as potential biomarkers for high grade human papillomavirus+ve pre-neoplastic cervical disease.
    Authors: Canham, Maurice, Charsou, Chara, Stewart, June, Moncur, Sharon, Hoodless, Laura, Bhatia, Ramya, Cong, Duanduan, Cubie, Heather, Busby-Earle, Camille, Williams, Alistair, McLoughlin, Victoria, Campbell, John D M, Cuschieri, Kate, Howie, Sarah
    PLoS ONE, 2014-12-22;9(12):e115379.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC-P
  272. DNMT-dependent suppression of microRNA regulates the induction of GBM tumor-propagating phenotype by Oct4 and Sox2.
    Authors: Lopez-Bertoni H, Lal B, Li A, Caplan M, Guerrero-Cazares H, Eberhart C, Quinones-Hinojosa A, Glas M, Scheffler B, Laterra J, Li Y
    Oncogene, 2014-10-20;34(30):3994-4004.
    Species: Human
    Sample Types: Cell Lysates
    Applications: ChIP
  273. In vitro generation of neuromesodermal progenitors reveals distinct roles for wnt signalling in the specification of spinal cord and paraxial mesoderm identity.
    Authors: Gouti, Mina, Tsakiridis, Anestis, Wymeersch, Filip J, Huang, Yali, Kleinjung, Jens, Wilson, Valerie, Briscoe, James
    PLoS Biol, 2014-08-26;12(8):e1001937.
    Species: Human
    Sample Types: Whole Cells
    Applications: IHC
  274. Lineage-specific splicing of a brain-enriched alternative exon promotes glioblastoma progression.
    Authors: Ferrarese R, Harsh G, Yadav A, Bug E, Maticzka D, Reichardt W, Dombrowski S, Miller T, Masilamani A, Dai F, Kim H, Hadler M, Scholtens D, Yu I, Beck J, Srinivasasainagendra V, Costa F, Baxan N, Pfeifer D, von Elverfeldt D, Backofen R, Weyerbrock A, Duarte C, He X, Prinz M, Chandler J, Vogel H, Chakravarti A, Rich J, Carro M, Bredel M
    J Clin Invest, 2014-05-27;124(7):2861-76.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  275. MOF-associated complexes ensure stem cell identity and Xist repression.
    Authors: Chelmicki T, Dundar F, Turley M, Khanam T, Aktas T, Ramirez F, Gendrel A, Wright P, Videm P, Backofen R, Heard E, Manke T, Akhtar A
    Elife, 2014-05-19;3(0):e02024.
    Species: Mouse
    Sample Types: Cell Lysates
    Applications: ChIP, Immunoprecipitation, Western Blot
  276. GATA6 levels modulate primitive endoderm cell fate choice and timing in the mouse blastocyst.
    Authors: Schrode N, Saiz N, Di Talia S, Hadjantonakis A
    Dev Cell, 2014-05-15;29(4):454-67.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  277. Neuronal activity promotes oligodendrogenesis and adaptive myelination in the mammalian brain.
    Authors: Gibson, Erin M, Purger, David, Mount, Christop, Goldstein, Andrea K, Lin, Grant L, Wood, Lauren S, Inema, Ingrid, Miller, Sarah E, Bieri, Gregor, Zuchero, J Bradle, Barres, Ben A, Woo, Pamelyn, Vogel, Hannes, Monje, Michelle
    Science, 2014-04-10;344(6183):1252304.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  278. Pharmacological inhibition of poly(ADP-ribose) polymerase-1 modulates resistance of human glioblastoma stem cells to temozolomide.
    Authors: Tentori, Lucio, Ricci-Vitiani, Lucia, Muzi, Alessia, Ciccarone, Fabio, Pelacchi, Federica, Calabrese, Roberta, Runci, Daniele, Pallini, Roberto, Caiafa, Paola, Graziani, Grazia
    BMC Cancer, 2014-03-05;14(0):151.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  279. Expression and regulation of prostate apoptosis response-4 (Par-4) in human glioma stem cells in drug-induced apoptosis.
    Authors: Jagtap, Jayashre, Dawood, Parveen, Shah, Reecha D, Chandrika, Goparaju, Natesh, Kumar, Shiras, Anjali, Hegde, Amba S, Ranade, Deepak, Shastry, Padma
    PLoS ONE, 2014-02-11;9(2):e88505.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  280. Positive feedback loop between Sox2 and Sox6 inhibits neuronal differentiation in the developing central nervous system.
    Authors: Lee, Kyung Eu, Seo, Jihae, Shin, Jiheon, Ji, Eun Hye, Roh, Jiwon, Kim, Joo Yeon, Sun, Woong, Muhr, Jonas, Lee, Sanghyuk, Kim, Jaesang
    Proc Natl Acad Sci U S A, 2014-02-05;111(7):2794-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  281. Role of SOX2 in the etiology of embryonal carcinoma, based on analysis of the NCCIT and NT2 cell lines.
    Authors: Eini, Ronak, Stoop, Hans, Gillis, Ad J M, Biermann, Katharin, Dorssers, Lambert, Looijenga, Leendert
    PLoS ONE, 2014-01-03;9(1):e83585.
    Species: Human
    Sample Types: Whole Cells
    Applications: IHC-P
  282. Otx2 cell-autonomously determines dorsal mesencephalon versus cerebellum fate independently of isthmic organizing activity.
    Authors: Di Giovannantonio, Luca G, Di Salvio, Michela, Omodei, Daniela, Prakash, Nilima, Wurst, Wolfgang, Pierani, Alessand, Acampora, Dario, Simeone, Antonio
    Development, 2013-12-11;141(2):377-88.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  283. The germinal matrices in the developing dentate gyrus are composed of neuronal progenitors at distinct differentiation stages.
    Authors: Sugiyama T, Osumi N, Katsuyama Y
    Dev Dyn, 2013-10-07;242(12):1442-53.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  284. Efficient generation of human iPSCs by a synthetic self-replicative RNA.
    Authors: Yoshioka N, Gros E, Li H, Kumar S, Deacon D, Maron C, Muotri A, Chi N, Fu X, Yu B, Dowdy S
    Cell Stem Cell, 2013-08-01;13(2):246-54.
    Species: Human
    Sample Types: Whole Cells
    Applications: IHC
  285. SOX2 expression associates with stem cell state in human ovarian carcinoma.
    Authors: Bareiss, Petra M, Paczulla, Anna, Wang, Hui, Schairer, Rebekka, Wiehr, Stefan, Kohlhofer, Ursula, Rothfuss, Oliver C, Fischer, Anna, Perner, Sven, Staebler, Annette, Wallwiener, Diethelm, Fend, Falko, Fehm, Tanja, Pichler, Bernd, Kanz, Lothar, Quintanilla-Martinez, Leticia, Schulze-Osthoff, Klaus, Essmann, Frank, Lengerke, Claudia
    Cancer Res, 2013-07-18;73(17):5544-55.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  286. Genome-wide chromatin interactions of the Nanog locus in pluripotency, differentiation, and reprogramming.
    Authors: Apostolou E, Ferrari F, Walsh R, Bar-Nur O, Stadtfeld M, Cheloufi S, Stuart H, Polo J, Ohsumi T, Borowsky M, Kharchenko P, Park P, Hochedlinger K
    Cell Stem Cell, 2013-05-09;12(6):699-712.
    Species: Mouse
    Sample Types: Cell Lysates
    Applications: ChIP, Co-Immunoprecipitation
  287. BEND6 is a nuclear antagonist of Notch signaling during self-renewal of neural stem cells.
    Authors: Dai Q, Andreu-Agullo C, Insolera R, Wong L, Shi S, Lai E
    Development, 2013-05-01;140(9):1892-902.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  288. Sex determining region Y-box 2 (SOX2) amplification is an independent indicator of disease recurrence in sinonasal cancer.
    Authors: Schrock A, Goke F, Wagner P, Bode M, Franzen A, Braun M, Huss S, Agaimy A, Ihrler S, Menon R, Kirsten R, Kristiansen G, Bootz F, Lengerke C, Perner S
    PLoS ONE, 2013-03-27;8(3):e59201.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC-P
  289. Sox2 marks epithelial competence to generate teeth in mammals and reptiles.
    Authors: Juuri, Emma, Jussila, Maria, Seidel, Kerstin, Holmes, Scott, Wu, Ping, Richman, Joy, Heikinheimo, Kristiin, Chuong, Cheng-Mi, Arnold, Katrin, Hochedlinger, Konrad, Klein, Ophir, Michon, Frederic, Thesleff, Irma
    Development, 2013-03-05;140(7):1424-32.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  290. Transcription factors FOXG1 and Groucho/TLE promote glioblastoma growth.
    Authors: Verginelli F, Perin A, Dali R, Fung K, Lo R, Longatti P, Guiot M, Del Maestro R, Rossi S, di Porzio U, Stechishin O, Weiss S, Stifani S
    Nat Commun, 2013-01-01;4(0):2956.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC-P
  291. Specific detection of OCT3/4 isoform A/B/B1 expression in solid (germ cell) tumours and cell lines: confirmation of OCT3/4 specificity for germ cell tumours.
    Authors: Rijlaarsdam MA, van Herk HA, Gillis AJ
    Br. J. Cancer, 2011-08-16;105(6):854-63.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC-P
  292. Sox2 cooperates with Chd7 to regulate genes that are mutated in human syndromes.
    Authors: Engelen E, Akinci U, Bryne JC
    Nat. Genet., 2011-05-01;43(6):607-11.
    Species: Human
    Sample Types: Cell Lysates, Whole Cells
    Applications: ChIP, ICC
  293. Sonic hedgehog signaling is decoded by calcium spike activity in the developing spinal cord.
    Authors: Belgacem YH, Borodinsky LN
    Proc. Natl. Acad. Sci. U.S.A., 2011-02-28;108(11):4482-7.
    Species: Xenopus
    Sample Types: Whole Tissue
    Applications: IHC
  294. A defined glycosaminoglycan-binding substratum for human pluripotent stem cells.
    Authors: Klim JR, Li L, Wrighton PJ
    Nat. Methods, 2010-11-14;7(12):989-94.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  295. Activity-dependent expression of Lmx1b regulates specification of serotonergic neurons modulating swimming behavior.
    Authors: Demarque M, Spitzer NC
    Neuron, 2010-07-29;67(2):321-34.
    Species: Xenopus
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  296. SIP1 mediates cell-fate decisions between neuroectoderm and mesendoderm in human pluripotent stem cells.
    Authors: Chng Z, Teo A, Pedersen RA, Vallier L
    Cell Stem Cell, 2010-01-08;6(1):59-70.
    Species: Human
    Sample Types: Cell Lysates
    Applications: ChIP
  297. Glioma stem cell lines expanded in adherent culture have tumor-specific phenotypes and are suitable for chemical and genetic screens.
    Authors: Pollard SM, Yoshikawa K, Clarke ID, Danovi D, Stricker S, Russell R, Bayani J, Head R, Lee M, Bernstein M, Squire JA, Smith A, Dirks P
    Cell Stem Cell, 2009-06-05;4(6):568-80.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  298. Hyaluronan-CD44 interaction activates stem cell marker Nanog, Stat-3-mediated MDR1 gene expression, and ankyrin-regulated multidrug efflux in breast and ovarian tumor cells.
    Authors: Bourguignon LY, Peyrollier K, Xia W, Gilad E
    J. Biol. Chem., 2008-04-25;283(25):17635-51.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  299. Regulation of self-renewal and pluripotency by Sox2 in human embryonic stem cells.
    Authors: Fong H, Hohenstein KA, Donovan PJ
    Stem Cells, 2008-04-03;26(8):1931-8.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  300. Epigenetic-mediated dysfunction of the bone morphogenetic protein pathway inhibits differentiation of glioblastoma-initiating cells.
    Authors: Lee J, Son MJ, Woolard K, Donin NM, Li A, Cheng CH, Kotliarova S, Kotliarov Y, Walling J, Ahn S, Kim M, Totonchy M, Cusack T, Ene C, Ma H, Su Q, Zenklusen JC, Zhang W, Maric D, Fine HA
    Cancer Cell, 2008-01-01;13(1):69-80.
    Species: Human, Mouse
    Sample Types: Whole Cells, Whole Tissue
    Applications: ICC, IHC
  301. Characterization of progenitor domains in the developing mouse thalamus.
    Authors: Vue TY, Aaker J, Taniguchi A
    J. Comp. Neurol., 2007-11-01;505(1):73-91.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  302. New cell lines from mouse epiblast share defining features with human embryonic stem cells.
    Authors: Tesar PJ, Chenoweth JG, Brook FA, Davies TJ, Evans EP, Mack DL, Gardner RL, McKay RD
    Nature, 2007-06-27;448(7150):196-9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  303. Microglia instruct subventricular zone neurogenesis.
    Authors: Walton NM, Sutter BM, Laywell ED, Levkoff LH, Kearns SM, Marshall GP, Scheffler B, Steindler DA
    Glia, 2006-12-01;54(8):815-25.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  304. CCDC154 Mutant Caused Abnormal Remodeling of the Otic Capsule and Hearing Loss in Mice
    Authors: Kai Xu, Xue Bai, Sen Chen, Le Xie, Yue Qiu, He Li et al.
    Frontiers in Cell and Developmental Biology
  305. SOX2 Co-Occupies Distal Enhancer Elements with Distinct POU Factors in ESCs and NPCs to Specify Cell State
    Authors: Michael A. Lodato, Christopher W. Ng, Joseph A. Wamstad, Albert W. Cheng, Kevin K. Thai, Ernest Fraenkel et al.
    PLoS Genetics
  306. Generation of highly enriched populations of optic vesicle-like retinal cells from human pluripotent stem cells.
    Authors: Ohlemacher SK, Iglesias CL, Sridhar A et al.
    Curr Protoc Stem Cell Biol
  307. Precision of tissue patterning is controlled by dynamical properties of gene regulatory networks
    Authors: Katherine Exelby, Edgar Herrera-Delgado, Lorena Garcia Perez, Ruben Perez-Carrasco, Andreas Sagner, Vicki Metzis et al.
    Development
  308. Prdm16 and Vcam1 regulate the postnatal disappearance of embryonic radial glia and the ending of cortical neurogenesis
    Authors: J Li, MI Godoy, AJ Zhang, G Diamante, IS Ahn, A Cebrian-Si, A Alvarez-Bu, X Yang, BG Novitch, Y Zhang
    bioRxiv : the preprint server for biology, 2023-02-14;0(0):.
  309. IFN-?-STAT1-mediated CD8+ T-cell-neural stem cell cross talk controls astrogliogenesis after spinal cord injury
    Authors: Wang J, Xu L, Peng D et al.
    Inflammation and regeneration
  310. An Optogenetic‐Controlled Cell Reprogramming System for Driving Cell Fate and Light‐Responsive Chimeric Mice
    Authors: Meiyan Wang, Yuanxiao Liu, Ziwei Wang, Longliang Qiao, Xiaoding Ma, Lingfeng Hu et al.
    Advanced Science
  311. Organization of self-advantageous niche by neural stem/progenitor cells during development via autocrine VEGF-A under hypoxia
    Authors: Taichi Kashiwagi, Yuuki Takazawa, Tetsushi Kagawa, Tetsuya Taga
    Inflammation and Regeneration
  312. Abundant Occurrence of Basal Radial Glia in the Subventricular Zone of Embryonic Neocortex of a Lissencephalic Primate, the Common Marmoset Callithrix jacchus
    Authors: Iva Kelava, Isabel Reillo, Ayako Y. Murayama, Alex T. Kalinka, Denise Stenzel, Pavel Tomancak et al.
    Cerebral Cortex
  313. Prospective Identification and Isolation of Enteric Nervous System Progenitors Using Sox2
    Authors: Tiffany A. Heanue, Vassilis Pachnis
    Stem Cells
  314. Veteran-derived cerebral organoids display multifaceted pathological defects in studies on Gulf War Illness
    Authors: Philip L. Yates, Kendra Case, Xiaohuan Sun, Kimberly Sullivan, Peter W. Baas, Liang Qiang
    Frontiers in Cellular Neuroscience
  315. Connexin 43 Gene Ablation Does Not Alter Human Pluripotent Stem Cell Germ Lineage Specification
    Authors: Grace A. Christopher, Rebecca J. Noort, Jessica L. Esseltine
    Biomolecules
  316. Benchmarking brain organoid recapitulation of fetal corticogenesis
    Authors: Cristina Cheroni, Sebastiano Trattaro, Nicolò Caporale, Alejandro López-Tobón, Erika Tenderini, Sara Sebastiani et al.
    Translational Psychiatry
  317. A Tug-of-War between Cell Shape and Polarity Controls Division Orientation to Ensure Robust Patterning in the Mouse Blastocyst
    Authors: Ritsuya Niwayama, Prachiti Moghe, Yan-Jun Liu, Dimitri Fabrèges, Frank Buchholz, Matthieu Piel et al.
    Developmental Cell
  318. Murine cerebral organoids develop network of functional neurons and hippocampal brain region identity
    Authors: Francesca Ciarpella, Raluca Georgiana Zamfir, Alessandra Campanelli, Elisa Ren, Giulia Pedrotti, Emanuela Bottani et al.
    iScience
  319. Generation of human elongating multi-lineage organized cardiac gastruloids
    Authors: Zachary T. Olmsted, Maria Belen Paredes-Espinosa, Janet L. Paluh
    STAR Protocols
  320. Neural-specific Sox2 input and differential Gli-binding affinity provide context and positional information in Shh-directed neural patterning
    Authors: Kevin A. Peterson, Yuichi Nishi, Wenxiu Ma, Anastasia Vedenko, Leila Shokri, Xiaoxiao Zhang et al.
    Genes & Development
  321. Glycan Epitope and Integrin Expression Dynamics Characterize Neural Crest Epithelial-to-Mesenchymal Transition (EMT) in Human Pluripotent Stem Cell Differentiation
    Authors: Ria Thomas, Vishal Menon, Rakesh Mani, Jan Pruszak
    Stem Cell Reviews and Reports
  322. Spatial and temporal expression of PORCN is highly dynamic in the developing mouse cochlea.
    Authors: Brianna L. Oliver, Caryl A. Young, Vidhya Munnamalai
    Gene Expression Patterns
  323. Intestinal microbiota shapes gut physiology and regulates enteric neurons and glia
    Authors: Fernando A. Vicentini, Catherine M. Keenan, Laurie E. Wallace, Crystal Woods, Jean-Baptiste Cavin, Amanda R. Flockton et al.
    Microbiome
  324. Sox2 Is an Oncogenic Driver of Small-Cell Lung Cancer and Promotes the Classic Neuroendocrine Subtype
    Authors: Ellen Voigt, Madeline Wallenburg, Hannah Wollenzien, Ethan Thompson, Kirtana Kumar, Joshua Feiner et al.
    Molecular Cancer Research
  325. Genetic deletion of genes in the cerebellar rhombic lip lineage can stimulate compensation through adaptive reprogramming of ventricular zone-derived progenitors
    Authors: Alexandre Wojcinski, Morgane Morabito, Andrew K. Lawton, Daniel N. Stephen, Alexandra L. Joyner
    Neural Development
  326. Follow-up study of subventricular zone progenitors with multiple rounds of cell division during sulcogyrogenesis in the ferret cerebral cortex
    Authors: Kazuhiko Sawada
    IBRO Reports
  327. Drug-Mediated Shortening of Action Potentials in LQTS2 Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes
    Authors: Gary Duncan, Karl Firth, Vinoj George, Minh Duc Hoang, Andrew Staniforth, Godfrey Smith et al.
    Stem Cells and Development
  328. Two novel DXZ4-associated long noncoding RNAs show developmental changes in expression coincident with heterochromatin formation at the human (Homo sapiens) macrosatellite repeat
    Authors: Debbie M. Figueroa, Emily M. Darrow, Brian P. Chadwick
    Chromosome Research
  329. Expression of the embryonic stem cell marker SOX2 in early-stage breast carcinoma
    Authors: Claudia Lengerke, Tanja Fehm, Ralf Kurth, Hans Neubauer, Veit Scheble, Friederike Müller et al.
    BMC Cancer
  330. The SOX2 response program in glioblastoma multiforme: an integrated ChIP-seq, expression microarray, and microRNA analysis
    Authors: Xuefeng Fang, Jae-Geun Yoon, Lisha Li, Wei Yu, Jiaofang Shao, Dasong Hua et al.
    BMC Genomics
  331. A fully automated high-throughput workflow for 3D-based chemical screening in human midbrain organoids
    Authors: Henrik Renner, Martha Grabos, Katharina J Becker, Theresa E Kagermeier, Jie Wu, Mandy Otto et al.
    eLife
  332. Nicotine Induces Progressive Properties of Lung Adenocarcinoma A549 Cells by Inhibiting Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Expression and Plasma Membrane Localization
    Authors: Hui Li, Ningxia Ma, Jing Wang, Ying Wang, Chao Yuan, Jing Wu et al.
    Technol. Cancer Res. Treat
  333. Human-specific ARHGAP11B induces hallmarks of neocortical expansion in developing ferret neocortex
    Authors: Nereo Kalebic, Carlotta Gilardi, Mareike Albert, Takashi Namba, Katherine R Long, Milos Kostic et al.
    eLife
  334. TNF alpha Induces Müller Glia to Transition From Non-proliferative Gliosis to a Regenerative Response in Mutant Zebrafish Presenting Chronic Photoreceptor Degeneration
    Authors: Maria Iribarne, David R. Hyde, Ichiro Masai
    Frontiers in Cell and Developmental Biology
  335. Zfp281 is essential for mouse epiblast maturation through transcriptional and epigenetic control of Nodal signaling
    Authors: Xin Huang, Sophie Balmer, Fan Yang, Miguel Fidalgo, Dan Li, Diana Guallar et al.
    eLife
  336. Growth factors with valproic acid restore injury-impaired hearing by promoting neuronal regeneration
    Authors: Takahiro Wakizono, Hideyuki Nakashima, Tetsuro Yasui, Teppei Noda, Kei Aoyagi, Kanako Okada et al.
    JCI Insight
  337. SOX9 maintains human foetal lung tip progenitor state by enhancing WNT and RTK signalling
    Authors: Dawei Sun, Oriol Llora Batlle, Jelle van den Ameele, John C Thomas, Peng He, Kyungtae Lim et al.
    The EMBO Journal
  338. Correction: Sox-2 Positive Neural Progenitors in the Primate Striatum Undergo Dynamic Changes after Dopamine Denervation
    Authors: Cristina Ordoñez, Paz Moreno-Murciano, Maria Hernandez, Carla Di Caudo, Iñaki-Carril Mundiñano, Nerea Vazquez et al.
    PLoS ONE
  339. Neonatal hyperoxia in mice triggers long-term cognitive deficits via impairments in cerebrovascular function and neurogenesis
    Authors: Marissa A. Lithopoulos, Xavier Toussay, Shumei Zhong, Liqun Xu, Shamimunisa B. Mustafa, Julie Ouellette et al.
    Journal of Clinical Investigation
  340. Cellular Origins of EGFR‐Driven Lung Cancer Cells Determine Sensitivity to Therapy
    Authors: Fan Chen, Jinpeng Liu, Robert M. Flight, Kassandra J. Naughton, Alexsandr Lukyanchuk, Abigail R. Edgin et al.
    Advanced Science
  341. YAP1 is involved in replenishment of granule cell precursors following injury to the neonatal cerebellum
    Authors: Zhaohui Yang, Alexandra L. Joyner
    Developmental Biology
  342. N6-methyladenine DNA Modification in Glioblastoma
    Authors: Qi Xie, Tao P. Wu, Ryan C. Gimple, Zheng Li, Briana C. Prager, Qiulian Wu et al.
    Cell
  343. Nervous System Regionalization Entails Axial Allocation before Neural Differentiation
    Authors: Vicki Metzis, Sebastian Steinhauser, Edvinas Pakanavicius, Mina Gouti, Despina Stamataki, Kenzo Ivanovitch et al.
    Cell
  344. Targeting glioma stem cells through combined BMI1 and EZH2 inhibition
    Authors: Xun Jin, Leo J. Y. Kim, Qiulian Wu, Lisa C. Wallace, Briana C. Prager, Tanwarat Sanvoranart et al.
    Nature Medicine
  345. Characterization of a novel transgenic mouse line expressing Cre recombinase under the control of the Cdx2 neural specific enhancer
    Authors: Baptiste Coutaud, Nicolas Pilon
    genesis
  346. A functional genetic toolbox for human tissue-derived organoids
    Authors: Dawei Sun, Lewis Evans, Francesca Perrone, Vanesa Sokleva, Kyungtae Lim, Saba Rezakhani et al.
    eLife
  347. Chd7 Collaborates with Sox2 to Regulate Activation of Oligodendrocyte Precursor Cells after Spinal Cord Injury
    Authors: Toru Doi, Toru Ogata, Junji Yamauchi, Yasuhiro Sawada, Sakae Tanaka, Motoshi Nagao
    The Journal of Neuroscience
  348. Three-dimensional organoid culture unveils resistance to clinical therapies in adult and pediatric glioblastoma
    Authors: SJ Sundar, S Shakya, A Barnett, LC Wallace, H Jeon, A Sloan, V Recinos, CG Hubert
    Translational Oncology, 2021-10-23;15(1):101251.
  349. Use of immunohistochemical biomarkers as independent predictor of neoplastic progression in Barrett's oesophagus surveillance: A systematic review and meta-analysis
    Authors: Vincent T. Janmaat, Sophie H. van Olphen, Katharina E. Biermann, Leendert H. J. Looijenga, Marco B. Bruno, Manon C. W. Spaander
    PLOS ONE
  350. Induced hepatic stem cells are suitable for human hepatocyte production
    Authors: Yoshiki Nakashima, Chika Miyagi-Shiohira, Issei Saitoh, Masami Watanabe, Masayuki Matsushita, Masayoshi Tsukahara et al.
    iScience
  351. EZH2 inhibition confers PIK3CA-driven lung tumors enhanced sensitivity to PI3K inhibition
    Authors: Chen F, Liu J, Song X Et al.
    Cancer Lett
  352. The Lineage-Defining Transcription Factors SOX2 and NkX2-1 Determine Lung Cancer Cell Fate and Shape the Tumor Immune Microenvironment.
    Authors: Mollaoglu G, Jones A, Wait SJ et al.
    Immunity.
  353. Hypoxia induces an early primitive streak signature, enhancing spontaneous elongation and lineage representation in gastruloids
    Authors: Natalia López-Anguita, Seher Ipek Gassaloglu, Maximilian Stötzel, Adriano Bolondi, Deniz Conkar, Marina Typou et al.
    Development
  354. Matrix-metalloproteinase expression and gelatinase activity in the avian retina and their influence on Müller glia proliferation
    Authors: Warren A. Campbell, Ameya Deshmukh, Sydney Blum, Levi Todd, Ninoshka Mendonca, Jessica Weist et al.
    Experimental Neurology
  355. Interleukin-6 requires JAK to stimulate inner cell mass expansion in bovine embryos
    Authors: Lydia K Wooldridge, Sally E Johnson, Rebecca R Cockrum, Alan D Ealy
    Reproduction
  356. Taste bud formation depends on taste nerves
    Authors: Di Fan, Zoubida Chettouh, G Giacomo Consalez, Jean-François Brunet
    eLife
  357. AMPK Signaling Regulates the Age-Related Decline of Hippocampal Neurogenesis
    Authors: Brian Z Wang, Jane J Yang, Hongxia Zhang, Charity A Smith, Kunlin Jin
    Aging and disease
  358. Cerebellar Granule Cell Replenishment Post-Injury by Adaptive Reprogramming of Nestin+ Progenitors
    Authors: Alexandre Wojcinski, Andrew K. Lawton, N Sumru. Bayin, Zhimin Lao, Daniel N. Stephen, Alexandra L. Joyner
    Nature Neuroscience
  359. Epiblast-like stem cells established by Wnt/ beta -catenin signaling manifest distinct features of formative pluripotency and germline competence
    Authors: Qing Luo, Han-pin Pui, Jiayu Chen, Leqian Yu, Paulo R. Jannig, Yu Pei et al.
    Cell Reports
  360. Modeling signaling-dependent pluripotency with Boolean logic to predict cell fate transitions
    Authors: A Yachie-Kin, K Onishi, J Ostblom, MA Langley, E Posfai, J Rossant, PW Zandstra
    Mol. Syst. Biol., 2018-01-29;14(1):e7952.
  361. Cooperative Binding of Transcription Factors Orchestrates Reprogramming
    Authors: Chronis C, Fiziev P, Papp B et al.
    Cell
  362. Structurally-discovered KLF4 variants accelerate and stabilize reprogramming to pluripotency
    Authors: Evgeniia Borisova, Ken Nishimura, Yuri An, Miho Takami, Jingyue Li, Dan Song et al.
    iScience
  363. Zika Virus Targets Glioblastoma Stem Cells through a SOX2-Integrin &alphav&beta5 Axis
    Authors: Z Zhu, P Mesci, JA Bernatchez, RC Gimple, X Wang, ST Schafer, HI Wettersten, S Beck, AE Clark, Q Wu, BC Prager, LJY Kim, R Dhanwani, S Sharma, A Garancher, SM Weis, SC Mack, PD Negraes, CA Trujillo, LO Penalva, J Feng, Z Lan, R Zhang, AW Wessel, S Dhawan, MS Diamond, CC Chen, RJ Wechsler-R, FH Gage, H Hu, JL Siqueira-N, AR Muotri, DA Cheresh, JN Rich
    Cell Stem Cell, 2020-01-16;26(2):187-204.e10.
  364. Regulation of embryonic and adult neurogenesis by Ars2
    Authors: Yang Yu, Celia Andreu-Agullo, Bing Fang Liu, Luendreo Barboza, Miklos Toth, Eric C. Lai
    Development
  365. Polysaccharides from Ganoderma lucidum Promote Cognitive Function and Neural Progenitor Proliferation in Mouse Model of Alzheimer's Disease
    Authors: Shichao Huang, Jianxin Mao, Kan Ding, Yue Zhou, Xianglu Zeng, Wenjuan Yang et al.
    Stem Cell Reports
  366. The Clinical and Molecular Characteristics of Sex-Determining Region Y-Box 2 and its Prognostic Value in Breast Cancer: A Systematic Meta-Analysis
    Authors: Gang Zhao, Xiaozhen Wang, Limei Qu, Zhu Zhu, Jinghui Hong, Haiqin Hou et al.
    Breast Care (Basel)
  367. Mutations in Spliceosomal Genes PPIL1 and PRP17 Cause Neurodegenerative Pontocerebellar Hypoplasia with Microcephaly
    Authors: Guoliang Chai, Alice Webb, Chen Li, Danny Antaki, Sangmoon Lee, Martin W. Breuss et al.
    Neuron
  368. Pitx2-Sox2-Lef-1 interactions specify progenitor oral/dental epithelial cell signaling centers
    Authors: Wenjie Yu, Zhao Sun, Yan Sweat, Mason Sweat, Shankar Rengasamy Venugopalan, Steven Eliason et al.
    Development
  369. A virus-free poly-promoter vector induces pluripotency in quiescent bovine cells under chemically defined conditions of dual kinase inhibition.
    Authors: Huang B, Li T, Alonso-Gonzalez L et al.
    PLoS One.

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Human/Mouse/Rat SOX2 Antibody
By Anonymous on 01/19/2024
Application: WB
Western Blot Human/Mouse/Rat SOX2 Antibody AF2018
Human/Mouse/Rat SOX2 Antibody
By Anonymous on 01/17/2022
Application: WB Sample Tested: Rat neurons Species: Rat
Western Blot Human/Mouse/Rat SOX2 Antibody AF2018
Human/Mouse/Rat SOX2 Antibody
By Pablo Hurtado on 10/09/2020
Application: Immunocytochemistry/Immunofluorescence Sample Tested: iPS2 human induced pluripotent stem cells Species: Human
Immunocytochemistry/Immunofluorescence Human/Mouse/Rat SOX2 Antibody AF2018
Human/Mouse/Rat SOX2 Antibody
By Anonymous on 07/31/2020
Application: Immunocytochemistry/Immunofluorescence Sample Tested: iPS cells Species: Human
Immunocytochemistry/Immunofluorescence Human/Mouse/Rat SOX2 Antibody AF2018
Human/Mouse/Rat SOX2 Antibody
By Chang Xie on 10/09/2019
Application: Immunocytochemistry/Immunofluorescence Sample Tested: Embryonic lung Species: Mouse
Immunocytochemistry/Immunofluorescence Human/Mouse/Rat SOX2 Antibody AF2018
Human/Mouse/Rat SOX2 Antibody
By Anonymous on 01/25/2018
Application: WB Sample Tested: IPS2 induced pluripotent stem cells Species: Mouse
Western Blot Human/Mouse/Rat SOX2 Antibody AF2018
Human/Mouse/Rat SOX2 Antibody
By Anonymous on 11/23/2017
Application: IHC Sample Tested: Embryonic stem cells differentiated into dopaminergic neurons Species: Human
Immunohistochemistry Human/Mouse/Rat SOX2 Antibody AF2018