Human/Mouse/Rat Rheb Alexa Fluor® 700-conjugated Antibody

Catalog #: FAB3426N Datasheet

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FAB3426N-100UG

All Rheb Antibodies

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Human/Mouse/Rat Rheb Alexa Fluor® 700-conjugated Antibody Summary

Species Reactivity

Human, Mouse, Rat

Specificity

Detects human, mouse, and rat Rheb.

Source

Monoclonal Mouse IgG2b Clone # 344912

Purification

Protein A or G purified

Immunogen

E. coli-derived recombinant human Rheb
Met1-Met184
Accession # AAH66307

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 700 (Excitation= 675-700 nm, Emission= 723 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Immunocytochemistry

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: Rheb

Ras homolog enriched in brain (Rheb) is a novel member of the Ras superfamily of GTP-binding proteins involved in cell growth and cell cycle progression. Expressed in a wide range of tissues, Rheb was initially identified from its induction in rat hippocampal granule cells by seizures and NMDA-dependent synaptic activity. A complex containing the tuberous sclerosis gene products TSC1 and TSC2 functions as a GTPase-activating protein (GAP) for Rheb.

Long Name

Ras Homolog Enriched In Brain

Entrez Gene IDs

6009 (Human); 19744 (Mouse); 26954 (Rat)

Alternate Names

GTP-binding protein Rheb; MGC111559; Ras homolog enriched in brainRHEB2Ras homolog enriched in brain 2; Rheb; Rheb2