Human/Mouse/Rat PP1 Catalytic Subunit Alexa Fluor® 647-conjugated Antibody

Catalog #: FAB3000R Datasheet

Catalog #	Availability	Size / Price	Qty
FAB3000R-100UG

All PP1 Antibodies

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Human/Mouse/Rat PP1 Catalytic Subunit Alexa Fluor® 647-conjugated Antibody Summary

Species Reactivity

Human, Mouse, Rat

Specificity

Detects endogenous human, mouse and rat PP1 alpha. Based on the amino acid homologies, the antibody is expected to cross‑react with PP1 beta and PP1 gamma.

Source

Monoclonal Mouse IgG2a Clone # 319319

Purification

Protein A or G purified

Immunogen

E. coli-derived recombinant human PP1Î± catalytic subunit
Lys41-Pro298
Accession # P62136

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 647 (Excitation= 650 nm, Emission= 668 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: PP1

Protein Phosphatase 1, also known as PP1 and PPP1, is an enzyme that removes phosphate groups attached to serine or threonine residues in proteins. The holoenzyme is composed of two subunits, a catalytic subunit (PP1ca) that is highly conserved throughout evolution, and a wide variety of regulatory subunits that target the enzyme to specific subcellular compartments and proteins. The catalytic subunit is ubiquitously expressed in tissues and cell lines.

Long Name

Protein Phosphatase 1

Entrez Gene IDs

5499 (Human); 19045 (Mouse); 24668 (Rat)

Alternate Names

PP1; PP1A;PP-1A;PP1alpha;PPP1A;PPP1CA;Serine/threonine-protein phosphatase;Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

Product Datasheets

Product Datasheet

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FAQs

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