Human/Mouse/Rat AMPK alpha 2 Alexa Fluor® 532-conjugated Antibody

Applications

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Preparation and Storage

Background: AMPK alpha 2

AMP-activated protein kinase (AMPK) is a heterotrimeric complex consisting of a catalytic alpha subunit and regulatory beta and gamma subunits. Each subunit exists as alternate isoforms ( alpha 1, alpha 2, beta 1, beta 2, gamma 1, gamma 2, gamma 3), with all 12 combinations able to form complexes. The catalytic alpha subunit of AMPK is activated allosterically by AMP, and by phosphorylation via the AMPK kinase LKB1. AMPK’s role in metabolic regulation has implicated this serine/threonine kinase as a therapeutic target in heart disease, obesity, and diabetes.

Product Datasheets

Related Research Areas

• Autophagy
• Growth Hormone/IGF-I Axis
• Intracellular Kinases
• Intracellular Kinases in the Akt Pathway
• Kinases and Phosphatases in Endothelial Cells
• Neurofibrillary Tangle Formation
• Obesity
• Search Kinases and Phosphatases