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Human/Mouse ID1 Alexa Fluor® 350-conjugated Antibody

Catalog #: AF4377U Datasheet
Catalog # Availability Size / Price Qty
AF4377U-100UG
Product Details
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Human/Mouse ID1 Alexa Fluor® 350-conjugated Antibody Summary

Species Reactivity
Human, Mouse
Specificity
Detects human and mouse ID1 in Western blots.
Source
Polyclonal Goat IgG
Purification
Antigen Affinity-purified
Immunogen
E. coli-derived recombinant mouse ID1
Met1-Glu135
Accession # P20067
Formulation
Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide
Label
Alexa Fluor 350 (Excitation= 346 nm, Emission= 442 nm)

Applications

Recommended Concentration
Sample
Western Blot
Optimal dilution of this antibody should be experimentally determined.
 
Immunocytochemistry
Optimal dilution of this antibody should be experimentally determined.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: ID1

ID-1a is a negative regulator of helix-loop-helix (HLH) DNA binding proteins. ID-1a contains a HLH motif but no DNA binding motif, therefore, upon binding other HLH proteins, ID-1a acts a dominant negative regulator. ID-1a can be found in both cytoplasmic and nuclear cell fractions. Increased ID-1a expression is associated with cellular proliferation and cancer.

Long Name
Inhibitor of DNA Binding 1
Entrez Gene IDs
3397 (Human); 15901 (Mouse); 25261 (Rat)
Alternate Names
BHLHB24; bHLHb24DNA-binding protein inhibitor ID-1; Class B basic helix-loop-helix protein 24; dJ857M17.1.2 (inhibitor of DNA binding 1, dominant negative helix-loop-helixprotein); dJ857M17.1.2; ID; ID1; inhibitor of differentiation 1; Inhibitor of DNA binding 1; inhibitor of DNA binding 1, dominant negative helix-loop-helix protein

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