Home / CXCL12/SDF-1 / Human/Mouse CXCL12/SDF-1 Antibody

Human/Mouse CXCL12/SDF-1 Antibody

Catalog #: MAB310
65 Citations Datasheet
Catalog # Availability Size / Price Qty
MAB310-SP
MAB310-100
MAB310-500
Chemotaxis Induced by CXCL12/SDF‑1 alpha and Neutral-ization by Human/Mouse CXCL12/SDF‑1 Antibody.
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Citations (65)
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Human/Mouse CXCL12/SDF-1 Antibody Summary

Species Reactivity
Human, Mouse
Specificity
Detects human and mouse CXCL12/SDF‑1 alpha and human CXCL12/SDF‑1 beta.
Source
Monoclonal Mouse IgG1 Clone # 79014
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
E. coli-derived recombinant human CXCL12/SDF‑1 alpha
Lys22-Lys89
Accession # Q6ICW0
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS and NaCl with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Endotoxin Level
<0.10 EU per 1 μg of the antibody by the LAL method.
Label
Unconjugated

Applications

Recommended Concentration
Sample
Neutralization

Measured by its ability to neutralize CXCL12/SDF‑1 alpha -induced chemotaxis in the BaF3 mouse pro‑B cell line transfected with human CXCR4. At 111 μg/mL, this antibody will neutralize > 50% of the chemotactic effect due to 2 ng/mL Recombinant Human/Feline/Rhesus Macaque CXCL12/SDF‑1 alpha.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Neutralization Chemotaxis Induced by CXCL12/SDF‑1 alpha and Neutral-ization by Human/Mouse CXCL12/SDF‑1 Antibody. View Larger

Chemotaxis Induced by CXCL12/SDF‑1 alpha and Neutral-ization by Human/Mouse CXCL12/SDF‑1 Antibody. Recombinant Human/Feline/ Rhesus Macaque CXCL12/ SDF-1a (Catalog # 350-NS) chemoattracts the BaF3 mouse pro-B cell line transfected with human CXCR4 in a dose-dependent manner (orange line). Chemotaxis elicited by Recombinant Human/Feline/ Rhesus Macaque CXCL12/ SDF-1a (2 ng/mL) is neutralized (green line) by increasing concentrations of Mouse Anti-Human/Mouse CXCL12/SDF-1 Monoclonal Antibody (Catalog # MAB310). At 111 µg/mL, this antibody will neutralize > 50% of the chemotactic effect.

In vivo assay Detection of Mouse CXCL12/SDF-1 by In vivo assay View Larger

Detection of Mouse CXCL12/SDF-1 by In vivo assay Enumeration of bone marrow and blood Lin−/Sca1+ cell numbers following stroke and SDF1-A Antibody.(A) Twenty-four hour post stroke+SDF1-A antibody mice show a marked increase in the number of Lin−/Sca1+ cells present in the bone marrow compared to controls. (B) Twenty-four hour post stroke mice showed a marked decrease in the mobilization of these cells to the blood. * P<0.05. Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/24465621), licensed under a CC-BY license. Not internally tested by R&D Systems.

In vivo assay Detection of Mouse CXCL12/SDF-1 by In vivo assay View Larger

Detection of Mouse CXCL12/SDF-1 by In vivo assay Administration of Lin−/Sca1+ cells post stroke.A. Administration of Lin−/Sca1+ cells post stroke significantly reduced infarct volume at 24 hours post stroke (*P<0.05). B. Administration of the Lin−/Sca1+ cells with an SDF1-A antibody (AB) no longer demonstrates a beneficial reduction in the infarct volume (p = NS). Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/24465621), licensed under a CC-BY license. Not internally tested by R&D Systems.

In vivo assay Detection of Mouse CXCL12/SDF-1 by In vivo assay View Larger

Detection of Mouse CXCL12/SDF-1 by In vivo assay Enumeration of bone marrow and blood Lin−/Sca1+ cell numbers following stroke and SDF1-A Antibody.(A) Twenty-four hour post stroke+SDF1-A antibody mice show a marked increase in the number of Lin−/Sca1+ cells present in the bone marrow compared to controls. (B) Twenty-four hour post stroke mice showed a marked decrease in the mobilization of these cells to the blood. * P<0.05. Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/24465621), licensed under a CC-BY license. Not internally tested by R&D Systems.

Preparation and Storage

Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS.
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Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: CXCL12/SDF-1

CXCL12, also known as SDF-1 (stromal cell-derived factor 1) and PBSF (Pre-B cell growth stimulatory factor), is a member of the CXC chemokine superfamily. Two alternatively spliced mRNAs encode CXCL12 alpha (89 aa residues) and CXCL12 beta (93 aa residues) that differ by the addition of 4 amino acids at the carboxy-terminus. Human and mouse CXCL12 are highly conserved. Mature human and mouse CXCL12 differ only by 1 amino acid.

Entrez Gene IDs
6387 (Human); 20315 (Mouse); 493806 (Feline); 574334 (Rhesus Macaque)
Alternate Names
chemokine (C-X-C motif) ligand 12; C-X-C motif chemokine 12; CXCL12; hIRH; hSDF-1; Intercrine reduced in hepatomas; IRH; PBSF; PBSFSDF-1a; Pre-B cell growth-stimulating factor; SCYB12; SDF1; SDF-1; SDF1A; SDF1B; SDF1SDF-1b; stromal cell-derived factor 1; TLSF; TLSF-a; TLSF-b; TPAR1

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Citations for Human/Mouse CXCL12/SDF-1 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

65 Citations: Showing 1 - 10
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  1. Secretion of SDF-1alpha by bone marrow-derived stromal cells enhances skin wound healing of C57BL/6 mice exposed to ionizing radiation
    Authors: Yannick Landry, Oanh Lê, Kimberly A. Mace, Terry E. Restivo, Christian M. Beauséjour
    Journal of Cellular and Molecular Medicine
  2. CREB1-driven CXCR4hi neutrophils promote skin inflammation in mouse models and human patients
    Authors: Chen, J;Bai, Y;Xue, K;Li, Z;Zhu, Z;Li, Q;Yu, C;Li, B;Shen, S;Qiao, P;Li, C;Luo, Y;Qiao, H;Dang, E;Yin, W;Gudjonsson, JE;Wang, G;Shao, S;
    Nature communications
  3. Inflammation triggers ILC3 patrolling of the intestinal barrier
    Authors: A Jarade, Z Garcia, S Marie, A Demera, I Prinz, P Bousso, JP Di Santo, N Serafini
    Nature Immunology, 2022-08-23;0(0):.
  4. Aberrant expression of selectin E, CXCL1, and CXCL13 in chronic endometritis
    Authors: Kotaro Kitaya, Tadahiro Yasuo
    Modern Pathology
  5. Endothelial‐immune crosstalk contributes to vasculopathy in nonalcoholic fatty liver disease
    Authors: Chun‐Yi Ng, Khang Leng Lee, Mark Dhinesh Muthiah, Kan Xing Wu, Florence Wen Jing Chioh, Konstanze Tan et al.
    EMBO reports
  6. Neural cell adhesion molecule is required for ventricular conduction system development
    Authors: Camila Delgado, Lei Bu, Jie Zhang, Fang-Yu Liu, Joseph Sall, Feng-Xia Liang et al.
    Development
  7. The Pivotal Role of CXCR7 in Stabilization of the Pulmonary Epithelial Barrier in Acute Pulmonary Inflammation
    Authors: Kristian-Christos Ngamsri, Anika Müller, Hans Bösmüller, Jutta Gamper-Tsigaras, Jörg Reutershan, Franziska M. Konrad
    The Journal of Immunology
  8. Stromal-derived MAOB promotes prostate cancer growth and progression
    Authors: Pu, T;Wang, J;Wei, J;Zeng, A;Zhang, J;Chen, J;Yin, L;Li, J;Lin, TP;Melamed, J;Corey, E;Gao, AC;Wu, BJ;
    Science advances
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  9. TET2-mediated mRNA demethylation regulates leukemia stem cell homing and self-renewal
    Authors: Li, Y;Xue, M;Deng, X;Dong, L;Nguyen, LXT;Ren, L;Han, L;Li, C;Xue, J;Zhao, Z;Li, W;Qing, Y;Shen, C;Tan, B;Chen, Z;Leung, K;Wang, K;Swaminathan, S;Li, L;Wunderlich, M;Mulloy, JC;Li, X;Chen, H;Zhang, B;Horne, D;Rosen, ST;Marcucci, G;Xu, M;Li, Z;Wei, M;Tian, J;Shen, B;Su, R;Chen, J;
    Cell stem cell
    Species: Transgenic Mouse
    Sample Types: Whole Cells
    Applications: Neutralization
  10. Interleukin-9 promotes mast cell progenitor proliferation and CCR2-dependent mast cell migration in allergic airway inflammation
    Authors: Pajulas, A;Fu, Y;Cheung, CCL;Chu, M;Cannon, A;Alakhras, N;Zhang, J;Ulrich, BJ;Nelson, AS;Zhou, B;Kaplan, MH;
    Mucosal immunology
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  11. CD26-negative and CD26-positive tissue-resident fibroblasts contribute to functionally distinct CAF subpopulations in breast cancer
    Authors: JM Houthuijze, R de Bruijn, E van der Bu, AP Drenth, E Wientjens, T Filipovic, E Bullock, CS Brambillas, EM Pulver, M Nieuwland, I de Rink, F van Diepen, S Klarenbeek, R Kerkhoven, VG Brunton, CLGJ Scheele, MC Boelens, J Jonkers
    Nature Communications, 2023-01-12;14(1):183.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Neutralization
  12. Tumor-infiltrated activated B cells suppress liver metastasis of colorectal cancers
    Authors: Y Xu, Z Wei, M Feng, D Zhu, S Mei, Z Wu, Q Feng, W Chang, M Ji, C Liu, Y Zhu, L Shen, F Yang, Y Chen, Y Feng, J Xu, D Zhu
    Cell Reports, 2022-08-30;40(9):111295.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  13. Engagement of the CXCL12-CXCR4 Axis in the Interaction of Endothelial Progenitor Cell and Smooth Muscle Cell to Promote Phenotype Control and Guard Vascular Homeostasis
    Authors: SF Mause, E Ritzel, A Deck, F Vogt, EA Liehn
    International Journal of Molecular Sciences, 2022-01-14;23(2):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  14. Combination of Fish Oil and Selenium Enhances Anticancer Efficacy and Targets Multiple Signaling Pathways in Anti-VEGF Agent Treated-TNBC Tumor-Bearing Mice
    Authors: CH Guo, S Hsia, CH Chung, YC Lin, MY Shih, PC Chen, GW Hsu, CT Fan, CL Peng
    Marine Drugs, 2021-03-29;19(4):.
    Species: Mouse
    Sample Types: Tissue Homogenates
    Applications: Western Blot
  15. Plasma cell dynamics in the bone marrow niche
    Authors: Z Benet, Z Jing, DR Fooksman
    Cell Reports, 2021-02-09;34(6):108733.
    Species: Mouse
    Sample Types: In Vivo, Whole Cells
    Applications: ELISA Capture, Neutralization
  16. Involvement of CXCL12/CXCR4 in the motility of human first-trimester endometrial epithelial cells through an autocrine mechanism by activating PI3K/AKT signaling
    Authors: J Zheng, D Qu, C Wang, L Ding, W Zhou
    BMC Pregnancy Childbirth, 2020-02-10;20(1):87.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  17. Reciprocal signaling and direct physical interactions between fibroblasts and breast cancer cells in a 3D environment
    Authors: DJ Wessels, N Pradhan, YN Park, MA Klepitsch, DF Lusche, KJ Daniels, KD Conway, ER Voss, SV Hegde, TP Conway, DR Soll
    PLoS ONE, 2019-06-24;14(6):e0218854.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  18. Periarteriolar Glioblastoma Stem Cell Niches Express Bone Marrow Hematopoietic Stem Cell Niche Proteins
    Authors: VVV Hira, JR Wormer, H Kakar, B Breznik, B van der Sw, R Hulsbos, W Tigchelaar, Z Tonar, M Khurshed, RJ Molenaar, CJF Van Noorde
    J. Histochem. Cytochem., 2018-01-03;0(0):2215541774917.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  19. Indian Hedgehog Suppresses a Stromal Cell-Driven Intestinal Immune Response
    Authors: BF Westendorp, NVJA Büller, ON Karpus, WA van Dop, J Koster, R Versteeg, PJ Koelink, CY Snel, S Meisner, JJTH Roelofs, A Uhmann, E Ver Loren, J Heijmans, H Hahn, V Muncan, ME Wildenberg, GR van den Br
    Cell Mol Gastroenterol Hepatol, 2017-09-05;5(1):67-82.e1.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  20. Stromal Cell-Derived Factor 1 Mediates Immune Cell Attraction upon Urinary Tract Infection
    Authors: B Isaacson, T Hadad, A Glasner, C Gur, Z Granot, G Bachrach, O Mandelboim
    Cell Rep, 2017-07-05;20(1):40-47.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Neutralization
  21. CYP4A in tumor-associated macrophages promotes pre-metastatic niche formation and metastasis
    Authors: XW Chen, TJ Yu, J Zhang, Y Li, HL Chen, GF Yang, W Yu, YZ Liu, XX Liu, CF Duan, HL Tang, M Qiu, CL Wang, H Zheng, J Yue, AM Guo, J Yang
    Oncogene, 2017-05-08;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
    Applications: Functional Assay
  22. Physiologically activated mammary fibroblasts promote postpartum mammary cancer
    Authors: Q Guo, J Minnier, J Burchard, K Chiotti, P Spellman, P Schedin
    JCI Insight, 2017-03-23;2(6):e89206.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Neutralization
  23. Cathepsin K cleavage of SDF-1? inhibits its chemotactic activity towards glioblastoma stem-like cells
    Authors: Vashendriya V V Hira
    Biochim. Biophys. Acta, 2016-12-28;0(0):.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  24. Intrafibrillar silicified collagen scaffold modulates monocyte to promote cell homing, angiogenesis and bone regeneration
    Authors: Ji-Hua Chen
    Biomaterials, 2016-10-31;113(0):203-216.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Neutralization
  25. Natural nitration of CXCL12 reduces its signaling capacity and chemotactic activity in vitro and abrogates intra-articular lymphocyte recruitment in vivo
    Authors: R Janssens, A Mortier, D Boff, V Vanheule, M Gouwy, C Franck, O Larsen, MM Rosenkilde, J Van Damme, FA Amaral, MM Teixeira, S Struyf, P Proost
    Oncotarget, 2016-09-20;7(38):62439-62459.
    Species: Mouse
    Sample Types: Cell Culture Supernates
    Applications: ELISA Development (Capture)
  26. Hepatic carcinoma-associated fibroblasts enhance immune suppression by facilitating the generation of myeloid-derived suppressor cells
    Oncogene, 2016-09-05;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  27. CXCR4+CD45- cells are niche forming for osteoclastogenesis via the SDF-1, CXCL7, and CX3CL1 signaling pathways in bone marrow
    Authors: Yoh Goto
    Stem Cells, 2016-07-08;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Neutralization
  28. Peritoneal Dissemination Requires an Sp1-Dependent CXCR4/CXCL12 Signaling Axis and Extracellular Matrix-Directed Spheroid Formation.
    Authors: Kasagi Y, Harada Y, Morodomi Y, Iwai T, Saito S, Yoshida K, Oki E, Saeki H, Ohgaki K, Sugiyama M, Onimaru M, Maehara Y, Yonemitsu Y
    Cancer Res, 2016-01-07;76(2):347-57.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Neutralization
  29. Lipopolysaccharide Promotes Choroidal Neovascularization by Up-Regulation of CXCR4 and CXCR7 Expression in Choroid Endothelial Cell.
    Authors: Feng Y, Guo H, Yuan F, Shen M
    PLoS ONE, 2015-08-19;10(8):e0136175.
    Species: Rat
    Sample Types: In Vivo
    Applications: Neutralization
  30. Mesenchymal Stem Cells Ameliorate Atherosclerotic Lesions via Restoring Endothelial Function.
    Authors: Lin Y, Yet S, Hsu Y, Wang G, Hung S
    Stem Cells Transl Med, 2014-12-10;4(1):44-55.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  31. CXCR4 and a cell-extrinsic mechanism control immature B lymphocyte egress from bone marrow.
    Authors: Beck T, Gomes A, Cyster J, Pereira J
    J Exp Med, 2014-11-17;211(13):2567-81.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Neutralization
  32. Vitamin D promotes vascular regeneration.
    Authors: Wong M, Leisegang M, Kruse C, Vogel J, Schurmann C, Dehne N, Weigert A, Herrmann E, Brune B, Shah A, Steinhilber D, Offermanns S, Carmeliet G, Badenhoop K, Schroder K, Brandes R
    Circulation, 2014-07-11;130(12):976-86.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Neutralization
  33. Platelet expression of stromal cell-derived factor-1 is associated with the degree of valvular aortic stenosis.
    Authors: Wurster T, Tegtmeyer R, Borst O, Rath D, Geisler T, Gawaz M, Bigalke B
    PLoS ONE, 2014-05-16;9(5):e97405.
    Species: Human
    Sample Types: Whole Cells
    Applications: Functional Assay
  34. An important role of the SDF-1/CXCR4 axis in chronic skin inflammation.
    Authors: Zgraggen, Silvana, Huggenberger, Reto, Kerl, Katrin, Detmar, Michael
    PLoS ONE, 2014-04-02;9(4):e93665.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Neutralization
  35. IL-17-induced CXCL12 recruits B cells and induces follicle formation in BALT in the absence of differentiated FDCs.
    Authors: Fleige H, Ravens S, Moschovakis G, Bolter J, Willenzon S, Sutter G, Haussler S, Kalinke U, Prinz I, Forster R
    J Exp Med, 2014-03-24;211(4):643-51.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Neutralization
  36. SDF1-a facilitates Lin-/Sca1+ cell homing following murine experimental cerebral ischemia.
    Authors: Mocco J, Afzal A, Ansari S, Wolfe A, Caldwell K, Connolly E, Scott E
    PLoS ONE, 2014-01-20;9(1):e85615.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Neutralization
  37. Hematopoietic stem cell cytokines and fibroblast growth factor-2 stimulate human endothelial cell-pericyte tube co-assembly in 3D fibrin matrices under serum-free defined conditions.
    Authors: Smith A, Bowers S, Stratman A, Davis G
    PLoS ONE, 2013-12-31;8(12):e85147.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  38. Inhibition of CXCR4-CXCL12 chemotaxis in melanoma by AMD11070.
    Authors: O'Boyle, G, Swidenbank, I, Marshall, H, Barker, C E, Armstrong, J, White, S A, Fricker, S P, Plummer, R, Wright, M, Lovat, P E
    Br J Cancer, 2013-03-28;108(8):1634-40.
    Species: Human
    Sample Types: Whole Cells
    Applications: IHC
  39. CXCL12-CXCR4 signaling is required for the maintenance of mouse spermatogonial stem cells.
    Authors: Yang, Qi-En, Kim, Dongwon, Kaucher, Amy, Oatley, Melissa, Oatley, Jon M
    J Cell Sci, 2012-12-13;126(0):1009-20.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Neutralization
  40. Stromal cell-derived factor-1 is essential for photoreceptor cell protection in retinal detachment.
    Authors: Otsuka H, Arimura N, Sonoda S
    Am. J. Pathol., 2010-10-01;177(5):2268-77.
    Species: Rat
    Sample Types: In Vivo
    Applications: Neutralization
  41. CXCR4 and CXCR7 regulate angiogenesis and CT26.WT tumor growth independent from SDF-1.
    Authors: Kollmar O, Rupertus K, Scheuer C, Nickels RM, Haberl GC, Tilton B, Menger MD, Schilling MK
    Int. J. Cancer, 2010-03-15;126(6):1302-15.
    Species: Mouse
    Sample Types: In Vivo, Whole Cells, Whole Tissue
    Applications: IHC-P, Neutralization
  42. Stimulation of chondrocyte hypertrophy by chemokine stromal cell-derived factor 1 in the chondro-osseous junction during endochondral bone formation.
    Authors: Wei L, Kanbe K, Lee M, Wei X, Pei M, Sun X, Terek R, Chen Q
    Dev. Biol., 2010-03-04;341(1):236-45.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  43. CXCL12 is essential for migration of activated Langerhans cells from epidermis to dermis.
    Authors: Ouwehand K, Santegoets SJ, Bruynzeel DP, Scheper RJ, de Gruijl TD, Gibbs S
    Eur. J. Immunol., 2008-11-01;38(11):3050-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  44. CXCL12 (SDF-1alpha) suppresses ongoing experimental autoimmune encephalomyelitis by selecting antigen-specific regulatory T cells.
    Authors: Meiron M, Zohar Y, Anunu R, Wildbaum G, Karin N
    J. Exp. Med., 2008-10-13;205(11):2643-55.
    Species: Mouse
    Sample Types: In Vivo, Recombinant Protein
    Applications: Neutralization, Western Blot
  45. Rapid chemotherapy-induced acute endothelial progenitor cell mobilization: implications for antiangiogenic drugs as chemosensitizing agents.
    Authors: Shaked Y, Henke E, Roodhart JM, Mancuso P, Langenberg MH, Colleoni M, Daenen LG, Man S, Xu P, Emmenegger U, Tang T, Zhu Z, Witte L, Strieter RM, Bertolini F, Voest EE, Benezra R, Kerbel RS
    Cancer Cell, 2008-09-09;14(3):263-73.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Neutralization
  46. Activation of bone marrow-derived microglia promotes photoreceptor survival in inherited retinal degeneration.
    Authors: Sasahara M, Otani A, Oishi A, Kojima H, Yodoi Y, Kameda T, Nakamura H, Yoshimura N
    Am. J. Pathol., 2008-05-15;172(6):1693-703.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Neutralization
  47. CXCL12 enhances exogenous CD4+CD25+ T cell migration and prevents embryo loss in non-obese diabetic mice.
    Authors: Lin Y, Xu L, Jin H, Zhong Y, Di J, Lin QD
    Fertil. Steril., 2008-04-02;91(6):2687-96.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  48. Cloning and expression pattern of dog SDF-1 and the implications of altered expression of SDF-1 in ischemic myocardium.
    Authors: Wei YJ, Tang Y, Li J, Cui CJ, Zhang H, Zhang XL, Zhang H, Hu SS
    Cytokine, 2007-10-01;40(1):52-9.
    Species: Canine
    Sample Types: Tissue Homogenates
    Applications: Western Blot
  49. Pulmonary stromal-derived factor-1 expression and effect on neutrophil recruitment during acute lung injury.
    Authors: Petty JM, Sueblinvong V, Lenox CC, Jones CC, Cosgrove GP, Cool CD, Rai PR, Brown KK, Weiss DJ, Poynter ME, Suratt BT
    J. Immunol., 2007-06-15;178(12):8148-57.
    Species: Mouse
    Sample Types: In Vivo, Whole Cells
    Applications: Neutralization
  50. Osteoblasts support B-lymphocyte commitment and differentiation from hematopoietic stem cells.
    Authors: Zhu J, Garrett R, Jung Y, Zhang Y, Kim N, Wang J, Joe GJ, Hexner E, Choi Y, Taichman RS, Emerson SG
    Blood, 2007-01-16;109(9):3706-12.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Neutralization
  51. SDF-1 is both necessary and sufficient to promote proliferative retinopathy.
    Authors: Butler JM, Guthrie SM, Koc M, Afzal A, Caballero S, Brooks HL, Mames RN, Segal MS, Grant MB, Scott EW
    J. Clin. Invest., 2005-01-01;115(1):86-93.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Neutralization
  52. The role of CCL21 in recruitment of T-precursor cells to fetal thymi.
    Authors: Ueno T, Kuse S, Saito F, Nitta T, Kakiuchi T, Hollander GA, Takahama Y
    Blood, 2004-09-09;105(1):31-9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Neutralization
  53. CXCR4 enhances adhesion of B16 tumor cells to endothelial cells in vitro and in vivo via beta(1) integrin.
    Authors: Cardones AR, Murakami T, Hwang ST
    Cancer Res., 2003-10-15;63(20):6751-7.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  54. Serum inactivation contributes to the failure of stromal-derived factor-1 to block HIV-I infection in vivo.
    Authors: Villalba S, Salvucci O, Aoki Y, De La Luz Sierra M, Gupta G, Davis D, Wyvill K, Little R, Yarchoan R, Tosato G
    J. Leukoc. Biol., 2003-07-22;74(5):880-8.
    Species: Human
    Sample Types: Serum, Whole Cells
    Applications: Flow Cytometry, Immunoprecipitation
  55. Activation of mTORC1 in subchondral bone preosteoblasts promotes osteoarthritis by stimulating bone sclerosis and secretion of CXCL12
    Authors: Chuangxin Lin, Liangliang Liu, Chun Zeng, Zhong-Kai Cui, Yuhui Chen, Pinling Lai et al.
    Bone Research
  56. Muscle-derived SDF-1 alpha /CXCL12 modulates endothelial cell proliferation but not exercise training-induced angiogenesis
    Authors: Mami Yamada, Chihiro Hokazono, Ken Tokizawa, Shuri Marui, Masahiro Iwata, Vitor A. Lira et al.
    American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
  57. CHEK2 represses breast stromal fibroblasts and their paracrine tumor-promoting effects through suppressing SDF-1 and IL-6
    Authors: Maha A. Al-Rakan, Siti-Faujiah Hendrayani, Abdelilah Aboussekhra
    BMC Cancer
  58. Bi-ligand surfaces with oriented and patterned protein for real-time tracking of cell migration
    Authors: Varadraj N. Vernekar, Charles S. Wallace, Mina Wu, Joshua T. Chao, Shannon K. O’Connor, Aimee Raleigh et al.
    Colloids and Surfaces B: Biointerfaces
  59. CD62Ldim Neutrophils Specifically Migrate to the Lung and Participate in the Formation of the Pre-Metastatic Niche of Breast Cancer
    Authors: Zhen Wang, Chenghui Yang, Lili Li, Zhigang Zhang, Jun Pan, Ke Su et al.
    Frontiers in Oncology
  60. A new obligate CXCL4-CXCL12 heterodimer for studying chemokine heterodimer activities and mechanisms
    Authors: KTP Nguyen, B Volkman, D Dréau, IV Nesmelova
    Scientific Reports, 2022-10-13;12(1):17204.
  61. Cytotoxic T cells swarm by homotypic chemokine signalling
    Authors: Jorge Luis Galeano Niño, Sophie V Pageon, Szun S Tay, Feyza Colakoglu, Daryan Kempe, Jack Hywood et al.
    eLife
  62. A novel CXCR4 antagonist counteracts paradoxical generation of cisplatin-induced pro-metastatic niches in lung cancer
    Authors: Giulia Bertolini, Valeria Cancila, Massimo Milione, Giuseppe Lo Russo, Orazio Fortunato, Nadia Zaffaroni et al.
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  63. ROS-Induced CXCR4 Signaling Regulates Mantle Cell Lymphoma (MCL) Cell Survival and Drug Resistance in the Bone Marrow Microenvironment via Autophagy
    Authors: Zheng Chen, Albert E. Teo, Nami McCarty
    Clinical Cancer Research
  64. Annexin 2–CXCL12 Interactions Regulate Metastatic Cell Targeting and Growth in the Bone Marrow
    Authors: Younghun Jung, Jingcheng Wang, Eunsohl Lee, Samantha McGee, Janice E. Berry, Kenji Yumoto et al.
    Molecular Cancer Research
  65. Bone Marrow Suppression by c-Kit Blockade Enhances Tumor Growth of Colorectal Metastases through the Action of Stromal Cell-Derived Factor-1
    Authors: Kathrin Rupertus, Gudrun C. Y. Haberl, Claudia Scheuer, Michael D. Menger, Martin K. Schilling, Otto Kollmar
    Journal of Oncology

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