Human Meteorin-like/METRNL Alexa Fluor® 405-conjugated Antibody

Catalog #: FAB78672V Datasheet

Recombinant Monoclonal Antibody

Catalog #	Availability	Size / Price	Qty
FAB78672V-100UG

All Meteorin-like/METRNL Antibodies

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Human Meteorin-like/METRNL Alexa Fluor® 405-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human Meteorin-like/METRNL in direct ELISAs.

Source

Monoclonal Rabbit IgG Clone # 2441D

Purification

Protein A or G purified

Immunogen

Chinese Hamster Ovary cell line, CHO-derived human Meteorin-like/METRNL
Gln46-Asp311
Accession # Q641Q3

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 405 (Excitation= 405 nm, Emission= 421 nm)

Applications

Recommended Concentration

Sample

Immunohistochemistry

Optimal dilution of this antibody should be experimentally determined.

Immunocytochemistry

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: Meteorin-like/METRNL

METRNL (Meteorin-like) is a cytoplasmic 30 kDa (predicted) member of the meteorin family of proteins. The name meteorin derives from the ability of the founding family member meteorin to transform glia into cells containing an extensive, meteor-like tail. It is expressed by neurons, and appears to function as a primer molecule that sets the stage for either cell differentiation or neurite outgrowth when it acts with Dclk1 and SerpinB1. Mature human METRNL is 266 amino acids (aa) in length (aa 46-311). It reportedly contains a signal sequence (aa 1-45), which suggests it may be secreted. Mature human and mouse METRNL share 79% aa sequence identity.

Entrez Gene IDs

284207 (Human); 210029 (Mouse); 316842 (Rat)

Alternate Names

Meteorin like; meteorin, glial cell differentiation regulator-like; meteorin-like protein; Meteorin-like; METRNL; MGC99788