Home / LILRB4/CD85k/ILT3 / Human LILRB4/CD85k/ILT3 Alexa Fluor® 488-conjugated Antibody

Human LILRB4/CD85k/ILT3 Alexa Fluor® 488-conjugated Antibody

Catalog #: FAB2425G Datasheet
Catalog # Availability Size / Price Qty
FAB2425G-100UG
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Human LILRB4/CD85k/ILT3 Alexa Fluor® 488-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects human LILRB4/CD85k/ILT3 in direct ELISAs and Western blots. In Western blots, no cross-reactivity with recombinant human (rh) ILT2, 4, 5, 6, rhLIR6, or rhLIR8 is observed.
Source
Monoclonal Mouse IgG2a Clone # 293622
Purification
Protein A or G purified
Immunogen
Mouse myeloma cell line NS0-derived recombinant human LILRB4/CD85k/ILT3
Pro17-His257
Accession # ABM86208
Formulation
Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide
Label
Alexa Fluor 488 (Excitation= 488 nm, Emission= 515-545 nm)

Applications

Recommended Concentration
Sample
Western Blot
Optimal dilution of this antibody should be experimentally determined.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: LILRB4/CD85k/ILT3

ILT3, designated CD85k and also known as Leukocyte Immunoglobulin-Like Receptor subfamily B member 4 (LILRB4) and Leukocyte Immunoglobulin-like Receptor 5 (LIR-5), is a type I membrane protein that contains cytoplasmic ITIM motifs and is involved in the down-regulation of immune responses. Expression of ILT3 is
up-regulated on tolerogenic dendritic cells.

Long Name
Leukocyte Immunoglobulin-like Receptor, Subfamily B (with TM and ITIM Domains), Member 4
Entrez Gene IDs
11006 (Human); 14728 (Mouse); 107128256 (Cynomolgus Monkey)
Alternate Names
CD85 antigen-like family member K; CD85k antigen; CD85k; HM18; ILT3; ILT-3; ILT3CD85K; leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains); LILRB4; LIR5; LIR5LILRB5; LIR-5subfamily B, member 4; member 4

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