Human Leptin Quantikine ELISA Kit Summary
Sample Values
Serum - Samples from apparently healthy volunteers were evaluated for the presence of human Leptin in this assay. No medical histories were available for the donors used in this study.Sample Type | Range (pg/mL) | Mean (pg/mL) |
Male Serum (n=16) | 2205-11,419 | 4760 |
Female Serum (n=36) | 3877-77,273 | 20,676 |
Five additional male serum samples fell below the lowest standard,15.6 pg/mL, when diluted 100-fold.
Condition | Day 1(pg/mL) | Day 5 (pg/mL) |
Unstimulated | ND | ND |
Stimulated | 152 | 75.9 |
Condition | Day 1 (pg/mL) | Day 2 (pg/mL) | Day 3 (pg/mL) |
Unstimulated* | 849 | 1549 | 1667 |
2 μM forskolin* | 1231 | 1699 | 2054 |
20 μM forskolin* | 1137 | 1725 | 2747 |
Product Summary
Precision
Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma
Intra-Assay Precision | Inter-Assay Precision | |||||
---|---|---|---|---|---|---|
Sample | 1 | 2 | 3 | 1 | 2 | 3 |
n | 20 | 20 | 20 | 40 | 40 | 40 |
Mean (pg/mL) | 64.5 | 146 | 621 | 65.7 | 146 | 581 |
Standard Deviation | 2.14 | 4.32 | 20 | 3.56 | 6.17 | 20.6 |
CV% | 3.3 | 3 | 3.2 | 5.4 | 4.2 | 3.5 |
Recovery
The recovery of Leptin spiked to three different levels throughout the range of the assay in various matrices was evaluated.
Sample Type | Average % Recovery | Range % |
---|---|---|
Cell Culture Media (n=5) | 98 | 94-102 |
Citrate Plasma (n=5) | 95 | 87-105 |
EDTA Plasma (n=5) | 99 | 85-112 |
Heparin Plasma (n=5) | 90 | 81-100 |
Serum (n=5) | 95 | 89-109 |
Linearity
Scientific Data
Product Datasheets
Preparation and Storage
Background: Leptin/OB
Leptin is a product of the mouse obese gene. Mice with mutations in the obese gene that block the synthesis of leptin are obese and diabetic, and have reduced activity, metabolism, and body temperature. Rat leptin shares approximately 96% and 82% sequence identity with the mouse and human protein, respectively. The expression of leptin mRNA is restricted to adipose tissue.
Assay Procedure
Refer to the product- Prepare all reagents, standard dilutions, and samples as directed in the product insert.
- Remove excess microplate strips from the plate frame, return them to the foil pouch containing the desiccant pack, and reseal.
- Add 100 µL of Assay Diluent to each well.
- Add 100 µL of Standard, control, or sample to each well. Cover with a plate sealer, and incubate at room temperature for 2 hours.
- Aspirate each well and wash, repeating the process 3 times for a total of 4 washes.
- Add 200 µL of Conjugate to each well. Cover with a new plate sealer, and incubate at room temperature for 1 hour.
- Aspirate and wash 4 times.
- Add 200 µL Substrate Solution to each well. Incubate at room temperature for 30 minutes. PROTECT FROM LIGHT.
- Add 50 µL of Stop Solution to each well. Read at 450 nm within 30 minutes. Set wavelength correction to 540 nm or 570 nm.
Citations for Human Leptin Quantikine ELISA Kit
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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No effect of circulating leptin on energy metabolism in normal weight or overweight/obese lactating mothers: The case-control Breastmilk and the Link to Overweight/Obesity and Maternal diet (BLOOM) study
Authors: Zielinska-Pukos, MA;Kopiasz, ?;Hamulka, J;
Clinical nutrition ESPEN
Species: Human
Sample Types: Serum
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Effects of high-intensity interval training on cardiometabolic biomarkers in patients with prostate cancer undergoing active surveillance: a randomized controlled trial
Authors: Kang, DW;Field, CJ;Patel, D;Fairey, AS;Boulé, NG;Dieli-Conwright, CM;Courneya, KS;
Prostate cancer and prostatic diseases
Species: Human
Sample Types: Serum
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Total Gestational Weight Gain Is Explained by Leptin and Body Fat, Regardless of Pre-Pregnancy Body Mass Index and Other Adipokines, in Mexican Adolescents
Authors: Chico-Barba, G;Sámano, R;Martínez-Rojano, H;Morales-Hernández, RM;Barrientos-Galeana, E;Luna-Hidalgo, A;Kaufer-Horwitz, M;Obrador, GT;Villa-Romero, AR;
Nutrients
Species: Human
Sample Types: Serum
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Adipocytokines levels as potential biomarkers for discriminating patients with a diagnosis of depressive disorder from healthy controls
Authors: Ma?uj?o-Balcerska, E;Pietras, T;
Journal of psychiatric research
Species: Human
Sample Types: Serum
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Linking adipose tissue eosinophils, interleukin-4, and leptin in human obesity and insulin resistance
Authors: Hernandez, JD;Li, T;Ghannam, H;Rau, CM;Masuda, MY;Madura, JA;Jacobsen, EA;Filippis, E;
JCI insight
Species: Human
Sample Types: Serum, Plasma
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Bronchoalveolar cytokine profile differentiates Pulmonary Langerhans cell histiocytosis patients from other smoking-related interstitial lung diseases
Authors: Barril, S;Acebo, P;Millan-Billi, P;Luque, A;Sibila, O;Tarín, C;Tazi, A;Castillo, D;Hortelano, S;
Respiratory research
Species: Human
Sample Types: BALF
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Effect of acute and long-term exercise on leptin levels in depressed outpatients
Authors: Heinen, D;Heissel, A;Heinzel, S;Fydrich, T;Ströhle, A;Rapp, MA;Vogel, H;
BMC public health
Species: Human
Sample Types: Serum
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Metabolic Syndrome and Adipokines Profile in Bipolar Depression
Authors: Bilska, K;Dmitrzak-W?glarz, M;Osip, P;Pawlak, J;Paszy?ska, E;Permoda-Pachuta, A;
Nutrients
Species: Human
Sample Types: Serum
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Novel Multi-Ingredient Supplement Facilitates Weight Loss and Improves Body Composition in Overweight and Obese Individuals: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial
Authors: Nederveen, JP;Mastrolonardo, AJ;Xhuti, D;Di Carlo, A;Manta, K;Fuda, MR;Tarnopolsky, MA;
Nutrients
Species: Human
Sample Types: Plasma
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Associations of three thermogenic adipokines with metabolic syndrome in obese and non-obese populations from the China plateau: the China Multi-Ethnic Cohort
Authors: Zhao, Z;Huang, J;Zhong, D;Wang, Y;Che, Z;Xu, Y;Hong, R;Qian, Y;Meng, Q;Yin, J;
BMJ open
Species: Human
Sample Types: Plasma
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Changes in objectively measured sleep after a multidisciplinary lifestyle intervention in children with abdominal obesity: A randomized trial
Authors: Catalán-Lambán, A;Ojeda-Rodríguez, A;Marti Del Moral, A;Azcona-Sanjulian, C;
Sleep medicine
Species: Human
Sample Types: Serum
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A single nuclei atlas of aging human abdominal subcutaneous white adipose tissue
Authors: Sparks, L;Whytock, K;Divoux, A;Sun, Y;Pino, M;Yu, G;Smith, S;Walsh, M;
Research square
Species: Human
Sample Types: Cell Culture Supernates
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Association of inflammatory biomarkers and disease activity with subclinical myocardial dysfunction in psoriatic arthritis
Authors: Pletikosic, I;Marasovic Krstulovic, D;Bakovic, D;Susilovic Grabovac, Z;Tandara, L;Martinovic Kaliterna, D;
Scientific reports
Species: Human
Sample Types: Serum
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Metformin Treatment of Hidradenitis Suppurativa: Effect on Metabolic Parameters, Inflammation, Cardiovascular Risk Biomarkers, and Immune Mediators
Authors: R Hambly, N Kearney, R Hughes, JM Fletcher, B Kirby
International Journal of Molecular Sciences, 2023-04-09;24(8):.
Species: Human
Sample Types: Serum
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Comparison of Diagnostic Models to Estimate the Risk of Metabolic Syndrome in a Chilean Pediatric Population: A Cross-Sectional Study
Authors: M Solorzano, G Granfeldt, N Ulloa, G Molina-Rec, R Molina-Luq, C Aguayo, F Petermann-, M Martorell
Metabolites, 2023-02-16;13(2):.
Species: Human
Sample Types: Serum
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Postnatal Leptin Levels Correlate with Breast Milk Leptin Content in Infants Born before 32 Weeks Gestation
Authors: T Chatmethak, ML Schmelzel, KJ Johnson, JR Walker, DA Santillan, TT Colaizy, RD Roghair
Nutrients, 2022-12-08;14(24):.
Species: Human
Sample Types: Plasma
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Leptin-producing monocytes in the airway submucosa may contribute to asthma pathogenesis
Authors: K Watanabe, M Suzukawa, S Kawauchi-W, S Igarashi, I Asari, S Imoto, H Tashimo, T Fukami, A Hebisawa, S Tohma, T Nagase, K Ohta
Respiratory investigation, 2022-11-09;0(0):.
Species: Human
Sample Types: Serum
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Association of serum leptin at 24-28�weeks gestation with initiation and progression of labor in women
Authors: KKR Branham, E Sherman, M Golzy, EZ Drobnis, LC Schulz
Scientific Reports, 2022-09-26;12(1):16016.
Species: Human
Sample Types: Serum
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Inflammatory and metabolic markers in relation to outcome of in vitro fertilization in a cohort of predominantly overweight and obese women
Authors: H Svensson, S Einarsson, D Olausson, L Kluge, C Bergh, S Edén, M Lönn, A Thurin-Kje
Scientific Reports, 2022-08-03;12(1):13331.
Species: Human
Sample Types: Serum
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Serum and Adipose Dipeptidyl Peptidase 4 in Cardiovascular Surgery Patients: Influence of Dipeptidyl Peptidase 4 Inhibitors
Authors: I Shibasaki, T Nakajima, T Fukuda, T Hasegawa, H Ogawa, G Tsuchiya, Y Takei, M Tezuka, T Kato, Y Kanazawa, Y Kano, T Kuwata, M Ouchi, S Toyoda, Y Aso, H Fukuda
Journal of Clinical Medicine, 2022-07-26;11(15):.
Species: Human
Sample Types: Serum
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Influence of NAFLD and bariatric surgery on hepatic and adipose tissue mitochondrial biogenesis and respiration
Authors: JS Pedersen, MO Rygg, K Chrøis, EG Sustarsic, Z Gerhart-Hi, NJ Wever Albr, RR Serizawa, VB Kristianse, AL Basse, AEB Boilesen, BH Olsen, T Hansen, LL Gluud, S Madsbad, S Larsen, F Bendtsen, F Dela
Nature Communications, 2022-05-25;13(1):2931.
Species: Human
Sample Types: Plasma
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Plasma concentration of Bisphenol A and leptin in patients with meningioma and glioma: A pilot study
Authors: M Komarowska, R Chrzanowsk, M Tylicka, R Rutkowski, Z Mariak, B Zelazowska, T Lyson, A Hermanowic
Advances in medical sciences, 2022-05-17;67(2):229-233.
Species: Human
Sample Types: Plasma
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Relationship between metabolic syndrome and follicle-stimulating hormone in postmenopausal women
Authors: SW Lee, IS Hwang, G Jung, HJ Kang, YH Chung
Medicine, 2022-05-06;101(18):e29216.
Species: Human
Sample Types: Serum
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Preventing White Adipocyte Browning during Differentiation In Vitro: The Effect of Differentiation Protocols on Metabolic and Mitochondrial Phenotypes
Authors: E Herbers, M Patrikoski, A Wagner, R Jokinen, A Hassinen, S Heinonen, S Miettinen, H Peltoniemi, E Pirinen, KH Pietiläine
Stem Cells International, 2022-04-05;2022(0):3308194.
Species: Human
Sample Types: Cell Culture Supernates
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The beneficial effects of intradialytic parenteral nutrition in hemodialysis patients with protein energy wasting: a prospective randomized controlled trial
Authors: P Kittiskuln, A Banjongjit, K Metta, K Tiranathan, Y Avihingsan, K Praditporn, K Tungsanga, S Eiam-Ong
Scientific Reports, 2022-03-16;12(1):4529.
Species: Human
Sample Types: Plasma
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Leptin-mediated proinflammatory bone marrow environment in acquired aplastic anemia
Authors: M Gao, M Ge, J Huo, X Ren, X Li, Y Shao, J Huang, J Zhang, M Wang, N Nie, P Jin, Y Zheng
Cytokine, 2022-02-23;152(0):155829.
Species: Human
Sample Types: Cell Culture Supernates
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Changes in adipokine levels and metabolic profiles following bariatric surgery
Authors: N Šebunova, J Štšepetova, T Kullisaar, K Suija, A Rätsep, I Junkin, H Soeorg, M Lember, T Sillakivi, R Mändar
BMC endocrine disorders, 2022-02-03;22(1):33.
Species: Human
Sample Types: Serum
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Relationship between Epicardial and Coronary Adipose Tissue and the Expression of Adiponectin, Leptin, and Interleukin 6 in Patients with Coronary Artery Disease
Authors: OV Gruzdeva, YA Dyleva, EV Belik, MY Sinitsky, AN Stasev, AN Kokov, NK Brel, EO Krivkina, EE Bychkova, RS Tarasov, OL Barbarash
Journal of personalized medicine, 2022-01-19;12(2):.
Species: Human
Sample Types: Cell Culture Media
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Roles of plasma leptin and resistin in novel subgroups of type 2 diabetes driven by cluster analysis
Authors: X Peng, J Huang, H Zou, B Peng, S Xia, K Dong, N Sun, J Tao, Y Yang
Lipids in Health and Disease, 2022-01-07;21(1):7.
Species: Human
Sample Types: Plasma
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Serum Leptin Levels, Nutritional Status, and the Risk of Healthcare-Associated Infections in Hospitalized Older Adults
Authors: E Paillaud, J Poisson, C Granier, A Ginguay, A Plonquet, C Conti, A Broussier, A Raynaud-Si, S Bastuji-Ga
Nutrients, 2022-01-05;14(1):.
Species: Human
Sample Types: Serum
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The Contribution of the Hunger Hormone Leptin in the Aetiology of Postoperative Anorexia after Laparoscopic and Open Gastrectomy in Gastric Cancer Patients
Authors: T Jagric
Biomolecules, 2021-10-29;11(11):.
Species: Human
Sample Types: Serum
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Improvement of Inflammation and Pain after Three Months' Exclusion Diet in Rheumatoid Arthritis Patients
Authors: MT Guagnano, C D'Angelo, D Caniglia, P Di Giovann, E Celletti, E Sabatini, L Speranza, M Bucci, F Cipollone, R Paganelli
Nutrients, 2021-10-09;13(10):.
Species: Human
Sample Types: Serum
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Exploring the Mechanisms of Recovery in Anorexia Nervosa through a Translational Approach: From Original Ecological Measurements in Human to Brain Tissue Analyses in Mice
Authors: P Duriez, IAK Nilsson, O Le Thuc, D Alexandre, N Chartrel, C Rovere, C Chauveau, P Gorwood, V Tolle, O Viltart
Nutrients, 2021-08-13;13(8):.
Species: Human
Sample Types: Plasma
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The Role of Leptin in Childhood Immune Thrombocytopenia (ITP): An Anti-Inflammatory Agent?
Authors: I Thomas, I Panagoulia, I Aggeletopo, A Varvarigou, BE Spiliotis, A Mouzaki
International Journal of Molecular Sciences, 2021-07-16;22(14):.
Species: Mouse
Sample Types: Plasma
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Adiponectin as a novel biomarker of disease severity in alopecia areata
Authors: A Stochmal, A Wa?kiel-Bu, S Chrostowsk, M Zaremba, A Rakowska, J Czuwara, L Rudnicka
Scientific Reports, 2021-07-05;11(1):13809.
Species: Human
Sample Types: Serum
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Physical activity during pregnancy and association with changes in fat mass and adipokines in women of normal-weight or with obesity
Authors: U Andersson-, H de Maré, F Askeli, M Börjesson, A Holmäng
Scientific Reports, 2021-06-15;11(1):12549.
Species: Human
Sample Types: Serum
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High-throughput drug screening models of mature adipose tissues which replicate the physiology of patients' Body Mass Index (BMI)
Authors: F Louis, Y Sowa, S Kitano, M Matsusaki
Bioactive materials, 2021-05-30;7(0):227-241.
Species: Human
Sample Types: Cell Culture Supernates
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Biomarkers of Oncogenesis, Adipose Tissue Dysfunction and Systemic Inflammation for the Detection of Hepatocellular Carcinoma in Patients with Nonalcoholic Fatty Liver Disease
Authors: GP Caviglia, A Armandi, C Rosso, S Gaia, S Aneli, E Rolle, ML Abate, A Olivero, A Nicolosi, M Guariglia, DG Ribaldone, P Carucci, GM Saracco, E Bugianesi
Cancers, 2021-05-11;13(10):.
Species: Human
Sample Types: Plasma
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Sex differences in the relationship between body composition and biomarkers of bone and fat metabolism in obese boys and girls
Authors: R Khwanchuea, C Punsawad
Bone Reports, 2021-05-04;14(0):101087.
Species: Human
Sample Types: Serum
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AntiTNF-alpha therapy normalizes levels of lipids and adipokines in psoriatic patients in the real-life settings
Authors: I Olejniczak, J Narbutt, J Ceryn, M Skibi?ska, I Bednarski, A Wo?niacka, J Sieniawska, M Kraska-Gac, M Ci??y?ska, J ?migielski, M Noweta, M Waszczykow, W Owczarek, A Reich, A Lesiak
Scientific Reports, 2021-04-29;11(1):9289.
Species: Human
Sample Types: Serum
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Expression of adipocytokines in heart fat depots depending on the degree of coronary artery atherosclerosis in patients with coronary artery disease
Authors: OV Gruzdeva, EV Belik, YA Dyleva, DA Borodkina, MY Sinitsky, DY Naumov, EE Bychkova, EV Fanaskova, EI Palicheva, AA Kuzmina, VN Karetnikov, OL Barbarash
PLoS ONE, 2021-03-18;16(3):e0248716.
Species: Human
Sample Types: Tissue Homogenates
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Level of Adiponectin, Leptin and Selected Matrix Metalloproteinases in Female Overweight Patients with Primary Gonarthrosis
Authors: J Jarecki, T Ma?ecka-Ma, I Polkowska, B Potoczniak, E Kosior-Jar, I Szerb, E Tomaszewsk, M Gutbier, M Dobrzy?ski, T Blicharski
Journal of Clinical Medicine, 2021-03-18;10(6):.
Species: Human
Sample Types: Serum
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Adipocytokines in Untreated Newly Diagnosed Rheumatoid Arthritis: Association with Circulating Chemokines and Markers of Inflammation
Authors: GK Vasileiadi, AC Lundell, Y Zhang, K Andersson, I Gjertsson, A Rudin, C Maglio
Biomolecules, 2021-02-21;11(2):.
Species: Human
Sample Types: Plasma
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Epigenetic Regulation of Processes Related to High Level of Fibroblast Growth Factor 21 in Obese Subjects
Authors: T P?atek, A Polus, J Góralska, U Ra?ny, A Dziewo?ska, A Micek, A Dembi?ska-, B Solnica, M Malczewska
Genes, 2021-02-21;12(2):.
Species: Human
Sample Types: Serum
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Lactobacillus plantarum 299v probiotic supplementation in men with stable coronary artery disease suppresses systemic inflammation
Authors: BC Hofeld, VK Puppala, S Tyagi, KW Ahn, A Anger, S Jia, NH Salzman, MJ Hessner, ME Widlansky
Scientific Reports, 2021-02-17;11(1):3972.
Species: Human
Sample Types: Plasma
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Association of Maternal Microbiota and Diet in Cord Blood Cytokine and Immunoglobulin Profiles
Authors: K Rio-Aige, I Azagra-Bor, M Massot-Cla, M Selma-Royo, A Parra-Llor, S González, I García-Man, M Castell, MJ Rodríguez-, MC Collado, FJ Pérez Cano
International Journal of Molecular Sciences, 2021-02-10;22(4):.
Species: Human
Sample Types: Plasma
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Association of serum adiponectin and myostatin levels with skeletal muscle in patients with obesity: A cross-sectional study
Authors: S Kurose, K Onishi, N Takao, T Miyauchi, K Takahashi, Y Kimura
PLoS ONE, 2021-01-19;16(1):e0245678.
Species: Human
Sample Types: Serum
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Pain in women with knee and/or hip osteoarthritis is related to systemic inflammation and to adipose tissue dysfunction: Cross-sectional results of the KHOALA cohort
Authors: J Sellam, AC Rat, S Fellahi, JP Bastard, W Ngueyon Si, HK Ea, X Chevalier, P Richette, J Capeau, F Guillemin, F Berenbaum
Seminars in arthritis and rheumatism, 2020-12-18;51(1):129-136.
Species: Human
Sample Types: Serum
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The Link between Obesity and Inflammatory Markers in the Development of Type 2 Diabetes in Men of Black African and White European Ethnicity
Authors: O Hakim, O Bello, M Ladwa, JL Peacock, AM Umpleby, G Charles-Ed, SA Amiel, LM Goff
Nutrients, 2020-12-11;12(12):.
Species: Human
Sample Types: Plasma
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APOE-&epsilon4-related differences in left thalamic microstructure in cognitively healthy adults
Authors: JP Mole, F Fasano, J Evans, R Sims, E Kidd, JP Aggleton, C Metzler-Ba
Sci Rep, 2020-11-13;10(1):19787.
Species: Human
Sample Types: Plasma
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Influence of Short-Term Hyperenergetic, High-Fat Feeding on Appetite, Appetite-Related Hormones, and Food Reward in Healthy Men
Authors: AE Thackray, SA Willis, DJ Clayton, DR Broom, G Finlayson, FR Goltz, JA Sargeant, RM Woods, DJ Stensel, JA King
Nutrients, 2020-08-29;12(9):.
Species: Human
Sample Types: Plasma
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Monounsaturated fat rapidly induces hepatic gluconeogenesis and whole-body insulin resistance
Authors: T Sarabhai, S Kahl, J Szendroedi, DF Markgraf, OP Zaharia, C Barosa, C Herder, F Wickrath, P Bobrov, JH Hwang, JG Jones, M Roden
JCI Insight, 2020-05-21;5(10):.
Species: Human
Sample Types: Serum
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Statin therapy is associated with lower prevalence of gut microbiota dysbiosis
Authors: S Vieira-Sil, G Falony, E Belda, T Nielsen, J Aron-Wisne, R Chakaroun, SK Forslund, K Assmann, M Valles-Col, TTD Nguyen, S Proost, E Prifti, V Tremaroli, N Pons, E Le Chateli, F Andreelli, JP Bastard, LP Coelho, N Galleron, TH Hansen, JS Hulot, C Lewinter, HK Pedersen, B Quinquis, C Rouault, H Roume, JE Salem, NB Søndertoft, S Touch, ME Dumas, SD Ehrlich, P Galan, JP Gøtze, T Hansen, JJ Holst, L Køber, I Letunic, J Nielsen, JM Oppert, M Stumvoll, H Vestergaar, JD Zucker, P Bork, O Pedersen, F Bäckhed, K Clément, J Raes
Nature, 2020-05-06;581(7808):310-315.
Species: Human
Sample Types: Serum
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Chronic mirabegron treatment increases human brown fat, HDL cholesterol, and insulin sensitivity
Authors: AE O'Mara, JW Johnson, JD Linderman, RJ Brychta, S McGehee, LA Fletcher, YA Fink, D Kapuria, TM Cassimatis, N Kelsey, C Cero, Z Abdul-Sate, F Piccinini, AS Baskin, BP Leitner, H Cai, CM Millo, W Dieckmann, M Walter, NB Javitt, Y Rotman, PJ Walter, M Ader, RN Bergman, P Herscovitc, KY Chen, AM Cypess
J. Clin. Invest., 2020-05-01;0(0):.
Species: Human
Sample Types: Plasma
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SIV Infection and the HIV Proteins Tat and Nef Induce Senescence in Adipose Tissue and Human Adipose Stem Cells, Resulting in Adipocyte Dysfunction
Authors: J Gorwood, T Ejlalmanes, C Bourgeois, M Mantecon, C Rose, M Atlan, D Desjardins, R Le Grand, B Fève, O Lambotte, J Capeau, V Béréziat, C Lagathu
Cells, 2020-04-01;9(4):.
Species: Human
Sample Types: Cell Culture Supernates
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Effects of underfeeding and oral vancomycin on gut microbiome and nutrient absorption in humans
Authors: A Basolo, M Hohenadel, QY Ang, P Piaggi, S Heinitz, M Walter, P Walter, S Parrington, DD Trinidad, RJ von Schwar, PJ Turnbaugh, J Krakoff
Nat. Med., 2020-03-23;26(4):589-598.
Species: Human
Sample Types: Plasma
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Circulating leptin levels are associated with adiposity in survivors of childhood brain tumors
Authors: ED Sims, WJ Jennings, B Empringham, A Fleming, C Portwine, DL Johnston, SM Zelcer, SR Rassekh, S Burrow, L Thabane, MC Samaan
Sci Rep, 2020-03-13;10(1):4711.
Species: Human
Sample Types: Plasma
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Associations between prenatal serum levels of leptin, IGF-I, and estradiol and adolescent mothers' height gain during and after pregnancy
Authors: R Sámano, H Martínez-R, G Chico-Barb, M Hernández-, R Guzmán, G Arteaga-Tr, MA Figueroa-P, RM Morales, G Martínez
PLoS ONE, 2020-02-11;15(2):e0228706.
Species: Human
Sample Types: Serum
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Association of serum leptin and adiponectin concentrations with echocardiographic parameters and pathophysiological states in patients with cardiovascular disease receiving cardiovascular surgery
Authors: T Sawaguchi, T Nakajima, A Haruyama, T Hasegawa, I Shibasaki, T Nakajima, H Kaneda, T Arikawa, S Obi, M Sakuma, H Ogawa, Y Takei, S Toyoda, F Nakamura, S Abe, H Fukuda, T Inoue
PLoS ONE, 2019-11-08;14(11):e0225008.
Species: Human
Sample Types: Serum
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Association between genetically determined leptin and blood lipids considering alcohol consumption: a Mendelian randomisation study
Authors: L Shen, JF Cordero, JS Wang, Y Shen, S Li, L Liang, Z Zou, C Li
BMJ Open, 2019-11-07;9(11):e026860.
Species: Human
Sample Types: Serum
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Breast Milk Supply of MicroRNA Associated with Leptin and Adiponectin Is Affected by Maternal Overweight/Obesity and Influences Infancy BMI
Authors: R Zamanillo, J Sánchez, F Serra, A Palou
Nutrients, 2019-10-28;11(11):.
Species: Human
Sample Types: Milk
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Biological variation of immunological blood biomarkers in healthy individuals and quality goals for biomarker tests
Authors: N Aziz, R Detels, JJ Quint, D Gjertson, T Ryner, AW Butch
BMC Immunol., 2019-09-14;20(1):33.
Species: Human
Sample Types: Serum
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Hormonal, metabolic and inflammatory circulating biomarker profiles in obese and non-obese Brazilian middle-aged women
Authors: LV Galvão-Mor, ACB Nascimento, IMSC D'Albuquer, MAS Sousa, HO Brito, MDDSB Nascimento, MB da Costa C, LMO Brito
PLoS ONE, 2019-09-11;14(9):e0222239.
Species: Human
Sample Types: Serum
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Multilevel defects in the hematopoietic niche in essential thrombocythemia
Authors: T Sun, M Ju, X Dai, H Dong, W Gu, Y Gao, R Fu, X Liu, Y Huang, W Liu, Y Chi, W Wang, H Li, Y Zhou, L Shi, R Yang, L Zhang
Haematologica, 2019-07-09;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
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Long Pentraxin 3 as a Broader Biomarker for Multiple Risk Factors in End-Stage Renal Disease: Association with All-Cause Mortality
Authors: MJ Valente, S Rocha, S Coimbra, C Catarino, P Rocha-Pere, E Bronze-da-, JG Oliveira, J Madureira, JC Fernandes, M do Sameiro, V Miranda, L Belo, A Santos-Sil
Mediators Inflamm., 2019-06-16;2019(0):3295725.
Species: Human
Sample Types: Plasma
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Maternal pre-pregnancy weight status modifies the influence of PUFAs and inflammatory biomarkers in breastmilk on infant growth
Authors: H Nuss, A Altazan, J Zabaleta, M Sothern, L Redman
PLoS ONE, 2019-05-29;14(5):e0217085.
Species: Human
Sample Types: Serum
-
High- or moderate-intensity training promotes change in cardiorespiratory fitness, but not visceral fat, in obese men: A randomised trial of equal energy expenditure exercise
Authors: J Gerosa-Net, VLG Panissa, PA Monteiro, DS Inoue, JPJ Ribeiro, C Figueiredo, AM Zagatto, JP Little, FS Lira
Respir Physiol Neurobiol, 2019-05-21;266(0):150-155.
Species: Human
Sample Types: Serum
-
Lower levels of leptin are associated with severity parameters in visceral leishmaniasis patients
Authors: AMDC Fievez, ML Silva-Frei, AQ Sousa, JR Santos-Oli, AM Da-Cruz
PLoS ONE, 2019-03-26;14(3):e0214413.
Species: Human
Sample Types: Serum
-
The effect of resistance exercise upon age-related systemic and local skeletal muscle inflammation
Authors: AK Ziegler, SM Jensen, P Schjerling, AL Mackey, JL Andersen, M Kjaer
Exp. Gerontol., 2019-03-21;121(0):19-32.
Species: Human
Sample Types: Serum
-
Sex difference in the mediation roles of an inflammatory factor (hsCRP) and adipokines on the relationship between adiposity and blood pressure
Authors: YD Yang, CJ Zheng, YH Dong, ZY Zou, Y Lv, ZH Wang, ZG Yang, S Wang, B Dong, J Ma
Hypertens. Res., 2019-02-28;0(0):.
Species: Human
Sample Types: Serum
-
FABP4 in Gestational Diabetes-Association between Mothers and Offspring
Authors: J Patro-Ma?y, M Trojnar, ? Kimber-Tro, R Mierzy?ski, J Bartosiewi, J Oleszczuk, B Leszczy?sk
J Clin Med, 2019-02-27;8(3):.
Species: Human
Sample Types: Serum
-
Daily walnut intake improves metabolic syndrome status and increases circulating adiponectin levels: randomized controlled crossover trial
Authors: HJ Hwang, Y Liu, HS Kim, H Lee, Y Lim, H Park
Nutr Res Pract, 2019-02-11;13(2):105-114.
Species: Human
Sample Types: Serum
-
Inter-ictal assay of peripheral circulating inflammatory mediators in migraine patients under adjunctive cervical non-invasive vagus nerve stimulation (nVNS): A proof-of-concept study
Authors: SR Chaudhry, IS Lendvai, S Muhammad, P Westhofen, J Kruppenbac, L Scheef, H Boecker, D Scheele, R Hurlemann, TM Kinfe
Brain Stimul, 2019-01-19;0(0):.
Species: Human
Sample Types: Serum
-
Developmental trajectories of body mass index from childhood into late adolescence and subsequent late adolescence-young adulthood cardiometabolic risk markers
Authors: K Oluwagbemi, AE Buyken, U Alexy, M Schmid, C Herder, U Nöthlings
Cardiovasc Diabetol, 2019-01-19;18(1):9.
Species: Human
Sample Types: Plasma
-
Serum CA125 and ascites leptin level ratio predicts baseline clinical resistance to first-line platinum-based treatment and poor prognosis in patients with high grade serous ovarian cancer
Authors: I Matte, P Garde-Gran, P Bessette, A Piché
Am J Cancer Res, 2019-01-01;9(1):160-170.
Species: Human
Sample Types: Ascites Fluid
-
Fasting plasma mannose levels are associated with insulin sensitivity independent of BMI in Japanese individuals with diabetes
Authors: E Amano, S Funakoshi, K Yoshimura, S Hirano, S Ohmi, H Takata, Y Terada, S Fujimoto
Diabetol Metab Syndr, 2018-12-04;10(0):88.
Species: Human
Sample Types: Serum
-
The circulating metabolome of human starvation
Authors: ML Steinhause, BA Olenchock, J O'Keefe, M Lun, KA Pierce, H Lee, L Pantano, A Klibanski, GI Shulman, CB Clish, PK Fazeli
JCI Insight, 2018-08-23;3(16):.
Species: Human
Sample Types: Plasma
-
Differences in biochemical markers between Heart-transplanted and Left Ventricular Assist Device implanted patients, during cardiac rehabilitation
Authors: V Racca, P Castiglion, C Panzarino, M Saresella, I Marventano, A Verde, F Oliva, M Ferratini
Sci Rep, 2018-07-17;8(1):10816.
Species: Human
Sample Types: Serum
-
The impact of human breast milk components on the infant metabolism
Authors: C Hellmuth, O Uhl, H Demmelmair, M Grunewald, R Auricchio, G Castillejo, IR Korponay-S, I Polanco, M Roca, SL Vriezinga, KJ Werkstette, B Koletzko, ML Mearin, FF Kirchberg
PLoS ONE, 2018-06-01;13(6):e0197713.
Species: Human
Sample Types: Milk
-
Development of Versatile Human In Vitro Vascularized Adipose Tissue Model with Serum-Free Angiogenesis and Natural Adipogenesis Induction
Authors: O Huttala, M Palmroth, P Hemminki, T Toimela, T Heinonen, T Ylikomi, JR Sarkanen
Basic Clin. Pharmacol. Toxicol., 2018-04-27;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
Association between UCP polymorphisms and adipokines with obesity in Mexican adolescents
Authors: R Sámano, C Huesca-Góm, R López-Maru, AK Hernández-, A Rodríguez-, M Tolentino, RM Morales, R Gamboa
J. Pediatr. Endocrinol. Metab., 2018-04-25;0(0):.
Species: Human
Sample Types: Serum
-
Follicular fluid levels of anti-M�llerian hormone, insulin-like growth factor 1 and leptin in women with fertility disorders
Authors: R Kucera, V Babuska, Z Ulcova-Gal, V Kulda, O Topolcan
Syst Biol Reprod Med, 2018-03-29;0(0):1-4.
Species: Human
Sample Types: Follicular Fluid
-
Plasma leptin, but not resistin, TNF-? and adiponectin, is associated with echocardiographic parameters of cardiac remodeling in patients with coronary artery disease
Authors: AD Farca?, A Rusu, MA Stoia, LA Vida-Simit
Cytokine, 2018-01-08;103(0):46-49.
Species: Human
Sample Types: Plasma
-
Interleukin-6 and leptin levels are associated with preoperative pain severity in patients with osteoarthritis but not with acute pain after total knee arthroplasty
Authors: S Azim, J Nicholson, MJ Rebecchi, W Galbavy, T Feng, S Rizwan, RA Reinsel, M Kaczocha, H Benveniste
Knee, 2018-01-08;0(0):.
Species: Human
Sample Types: Serum
-
C-Reactive protein in relation to fecundability and anovulation among eumenorrheic women
Authors: RG Radin, LA Sjaarda, RM Silver, CJ Nobles, SL Mumford, NJ Perkins, BD Wilcox, AZ Pollack, KC Schliep, TC Plowden, EF Schisterma
Fertil. Steril., 2018-01-06;0(0):.
Species: Human
Sample Types: Serum
-
Key Clinical Factors Predicting Adipokine and Oxidative Stress Marker Concentrations among Normal, Overweight and Obese Pregnant Women Using Artificial Neural Networks
Authors: M Solis-Pare, G Estrada-Gu, O Perichart-, A Montoya-Es, M Guzmán-Hue, H Borboa-Oli, E Bravo-Flor, A Cardona-Pé, V Zaga-Clave, E Garcia-Lat, G Gonzalez-P, JA Hernández-, C Irles
Int J Mol Sci, 2017-12-28;19(1):.
Species: Human
Sample Types: Serum
-
Is There Any Relationship between Plasma 25-Hydroxyvitamin D?, Adipokine Profiles and Excessive Body Weight in Type 2 Diabetic Patients?
Authors: J Kocot, P Dziemidok, M Kie?czykow, J Kurzepa, G Szcze?niak, I Musik
Int J Environ Res Public Health, 2017-12-23;15(1):.
Species: Human
Sample Types: Plasma
-
Myostatin and adipokines: The role of the metabolically unhealthy obese phenotype in muscle function and aerobic capacity in young adults
Authors: LP Carvalho, RP Basso-Vane, L Di Thommaz, RG Mendes, MC Oliveira-J, RP Vieira, JC Bonjorno-J, CR Oliveira, R Luporini, A Borghi-Sil
Cytokine, 2017-12-13;0(0):.
Species: Human
Sample Types: Plasma
-
Plasma irisin is elevated in type 2 diabetes and is associated with increased E-selectin levels
Authors: KS Rana, C Pararasa, I Afzal, DA Nagel, EJ Hill, CJ Bailey, HR Griffiths, I Kyrou, HS Randeva, S Bellary, JE Brown
Cardiovasc Diabetol, 2017-11-09;16(1):147.
Species: Human
Sample Types: Plasma
-
Endurance exercise training decreased serum levels of surfactant protein D and improved aerobic fitness of obese women with type-2 diabetes
Authors: S Rezaei, MM Shamsi, M Mahdavi, A Jamali, J Prestes, RA Tibana, JW Navalta, FA Voltarelli
Diabetol Metab Syndr, 2017-09-25;9(0):74.
Species: Human
Sample Types: Serum
-
Serum levels of adiponectin and leptin as biomarkers of proteinuria in lupus nephritis
Authors: V Diaz-Rizo, D Bonilla-La, L Gonzalez-L, D Sanchez-Mo, NS Fajardo-Ro, EE Perez-Guer, NA Rodriguez-, AM Saldaña-Cr, ML Vazquez-Vi, E Gomez-Bañu, M Vazquez-De, EG Cardona-Mu, D Cardona-Mu, X Trujillo, M Huerta, M Salazar-Pa, JI Gamez-Nava
PLoS ONE, 2017-09-12;12(9):e0184056.
Species: Human
Sample Types: Serum
-
Inkjet-printed point-of-care immunoassay on a nanoscale polymer brush enables subpicomolar detection of analytes in blood
Authors: DY Joh, AM Hucknall, Q Wei, KA Mason, ML Lund, CM Fontes, RT Hill, R Blair, Z Zimmers, RK Achar, D Tseng, R Gordan, M Freemark, A Ozcan, A Chilkoti
Proc. Natl. Acad. Sci. U.S.A., 2017-08-07;0(0):.
Species: Human
Sample Types: Serum
-
Adipokines, C-reactive protein and Amyotrophic Lateral Sclerosis - results from a population- based ALS registry in Germany
Authors: G Nagel, RS Peter, A Rosenbohm, W Koenig, L Dupuis, D Rothenbach, AC Ludolph
Sci Rep, 2017-06-29;7(1):4374.
Species: Human
Sample Types: Serum
-
Concurrent Aerobic and Resistance Training Has Anti-Inflammatory Effects and Increases Both Plasma and Leukocyte Levels of IGF-1 in Late Middle-Aged Type 2 Diabetic Patients
Authors: G Annibalini, F Lucertini, D Agostini, L Vallorani, A Gioacchini, E Barbieri, M Guescini, L Casadei, A Passalia, M Del Sal, G Piccoli, M Andreani, A Federici, V Stocchi
Oxid Med Cell Longev, 2017-06-21;2017(0):3937842.
Species: Human
Sample Types: Plasma
-
Carbohydrates from Sources with a Higher Glycemic Index during Adolescence: Is Evening Rather than Morning Intake Relevant for Risk Markers of Type 2 Diabetes in Young Adulthood?
Authors: T Diederichs, C Herder, S Ro beta bach, M Roden, SA Wudy, U Nöthlings, U Alexy, AE Buyken
Nutrients, 2017-06-10;9(6):.
Species: Human
Sample Types: Serum
-
Reproductive hormones and metabolic syndrome in 24 testicular cancer survivors and their biological brothers
Authors: M Bandak, N Jørgensen, A Juul, J Lauritsen, MGG Kier, MS Mortensen, PS Oturai, J Mortensen, P Hojman, JW Helge, G Daugaard
Andrology, 2017-06-09;0(0):.
Species: Human
Sample Types: Serum
-
Type II Endometrial Cancer Overexpresses NILCO: A Preliminary Evaluation
Authors: D Daley-Brow, G Oprea-Iles, KT Vann, V Lanier, R Lee, PV Candelaria, A Quarshie, R Pattillo, RR Gonzalez-P
Dis. Markers, 2017-06-04;2017(0):8248175.
Species: Human
Sample Types: Tissue Homogenates
-
Class II obese and healthy pregnant controls exhibit indistinguishable pro- and anti-inflammatory immune responses to Caesarian section
Authors: C Graham, M Thorleifso, WP Stefura, DJ Funk, KT HayGlass
Immun Inflamm Dis, 2017-05-25;0(0):.
Species: Human
Sample Types: Plasma
-
Serum levels of leptin and adiponectin and clinical parameters in women with fibromyalgia and overweight/obesity
Authors: ES Paiva, A Andretta, ED Batista, MM Lobo, RC Miranda, R Nisihara, ME Schieferde, CL Boguszewsk
Arch Endocrinol Metab, 2017-02-13;0(0):0.
Species: Human
Sample Types: Serum
-
Effects of exercise training on circulating levels of Dickkpof-1 and secreted frizzled-related protein-1 in breast cancer survivors: A pilot single-blind randomized controlled trial
Authors: TH Kim, JS Chang, KS Park, J Park, N Kim, JI Lee, ID Kong
PLoS ONE, 2017-02-08;12(2):e0171771.
Species: Human
Sample Types: Serum
-
Impact of physical activity level and dietary fat content on passive overconsumption of energy in non-obese adults
Authors: K Beaulieu, M Hopkins, J Blundell, G Finlayson
Int J Behav Nutr Phys Act, 2017-02-06;14(1):14.
Species: Human
Sample Types: Plasma
-
Type 3 Deiodinase Role on Central Thyroid Hormone Action Affects the Leptin-Melanocortin System and Circadian Activity
Authors: Zhaofei Wu
Endocrinology, 2017-02-01;0(0):en20161680.
Species: Human
Sample Types: Serum
-
Relationships of insulin-like growth factor-1, its binding proteins, and cardiometabolic risk in hypertensive perimenopausal women
Authors: A Olszanecka, A Dragan, K Kawecka-Ja, D Fedak, D Czarnecka
Metab. Clin. Exp., 2017-01-12;69(0):96-106.
Species: Human
Sample Types: Plasma
-
The effect of BMI, serum leptin, and adiponectin levels on prognosis in patients with non-ischaemic dilated cardiomyopathy
Authors: C Wojciechow, W Jache?, E Romuk, E Nowalany-K, A Tomasik, L Siemi?ska
Endokrynol Pol, 2017-01-01;68(1):26-34.
Species: Human
Sample Types: Serum
-
Metabolic Syndrome and Selective Inflammatory Markers in Psoriatic Patients
Authors: S Vachatova, C Andrys, J Krejsek, M Salavec, K Ettler, V Rehacek, E Cermakova, A Malkova, Z Fiala, L Borska
J Immunol Res, 2016-12-21;2016(0):5380792.
Species: Human
Sample Types: Serum
-
Dietary patterns and cardiometabolic and endocrine plasma biomarkers in US women
Authors: Hala B AlEssa
Am. J. Clin. Nutr, 2016-12-14;0(0):.
Species: Human
Sample Types: Plasma
-
Leptin, Leptin Soluble Receptor, and the Free Leptin Index following a Diet and Physical Activity Lifestyle Intervention in Obese Males and Females
Authors: Jeffrey E Herrick
J Obes, 2016-12-06;2016(0):8375828.
Species: Human
Sample Types: Serum
-
Altered Systemic Adipokines in Patients with Chronic Urticaria
Authors: Hoang Kim Tu Trinh
Int. Arch. Allergy Immunol, 2016-12-01;171(2):102-110.
Species: Human
Sample Types: Serum
-
Effects of different degrees of insulin resistance on endothelial function in�obese�adults undergoing alternate day�fasting
Authors: Kristin K Hoddy
Nutr Healthy Aging, 2016-10-27;4(1):63-71.
Species: Human
Sample Types: Plasma
-
Ghrelin and hormonal markers under exercise training in patients with heart failure with preserved ejection fraction: results from the Ex-DHF pilot study
Authors: TD Trippel, V Holzendorf, M Halle, G Gelbrich, K Nolte, A Duvinage, S Schwarz, T Rutscher, J Wiora, R Wachter, C Herrmann-L, HD Duengen, G Hasenfu beta, B Pieske, F Edelmann
ESC Heart Fail, 2016-08-31;4(1):56-65.
Species: Human
Sample Types: Serum
-
Maternal obesity drives functional alterations in uterine NK cells
JCI Insight, 2016-07-21;1(11):e85560.
Species: Human
Sample Types: Serum
-
A Dietary Supplement Containing Cinnamon, Chromium and Carnosine Decreases Fasting Plasma Glucose and Increases Lean Mass in Overweight or Obese Pre-Diabetic Subjects: A Randomized, Placebo-Controlled Trial.
Authors: Liu Y, Cotillard A, Vatier C, Bastard J, Fellahi S, Stevant M, Allatif O, Langlois C, Bieuvelet S, Brochot A, Guilbot A, Clement K, Rizkalla S
PLoS ONE, 2015-09-25;10(9):e0138646.
Species: Human
Sample Types: Plasma
-
Circulating adipokines and insulin resistance in subjects with combined cardiac and metabolic syndrome X.
Authors: Liang K, Lee W, Lee W, Liao Y, Wang K, Lee I, Wang J, Sheu W
Diabetol Metab Syndr, 2015-09-24;7(0):83.
Species: Human
Sample Types: Serum
-
Lower Circulating C1q/TNF-Related Protein-3 (CTRP3) Levels Are Associated with Obesity: A Cross-Sectional Study.
Authors: Wolf R, Steele K, Peterson L, Magnuson T, Schweitzer M, Wong G
PLoS ONE, 2015-07-29;10(7):e0133955.
Species: Human
Sample Types: Serum
-
Inflammation-regulating factors in ascites as predictive biomarkers of drug resistance and progression-free survival in serous epithelial ovarian cancers.
Authors: Lane D, Matte I, Garde-Granger P, Laplante C, Carignan A, Rancourt C, Piche A
BMC Cancer, 2015-07-01;15(0):492.
Species: Human
Sample Types: Peritoneal Fluid
-
Cord blood adipokines, neonatal anthropometrics and postnatal growth in offspring of Hispanic and Native American women with diabetes mellitus.
Authors: Teague A, Fields D, Aston C, Short K, Lyons T, Chernausek S
Reprod Biol Endocrinol, 2015-06-26;13(0):68.
Species: Human
Sample Types: Serum
-
Additive regulation of adiponectin expression by the mediterranean diet olive oil components oleic Acid and hydroxytyrosol in human adipocytes.
Authors: Scoditti E, Massaro M, Carluccio M, Pellegrino M, Wabitsch M, Calabriso N, Storelli C, De Caterina R
PLoS ONE, 2015-06-01;10(6):e0128218.
Species: Human
Sample Types: Cell Culture Supernates
-
Leptin levels are negatively correlated with 2-arachidonoylglycerol in the cerebrospinal fluid of patients with osteoarthritis.
Authors: Nicholson J, Azim S, Rebecchi M, Galbavy W, Feng T, Reinsel R, Rizwan S, Fowler C, Benveniste H, Kaczocha M
PLoS ONE, 2015-04-02;10(4):e0123132.
Species: Human
Sample Types: Serum
-
A cross-over experiment to investigate possible mechanisms for lower BMIs in people who habitually eat breakfast.
Authors: Reeves S, Huber J, Halsey L, Villegas-Montes M, Elgumati J, Smith T
Eur J Clin Nutr, 2015-01-07;69(5):632-7.
Species: Human
Sample Types: Serum
-
Short-term intake of a Japanese-style healthy lunch menu contributes to prevention and/or improvement in metabolic syndrome among middle-aged men: a non-randomized controlled trial.
Authors: Inoue H, Sasaki R, Aiso I, Kuwano T
Lipids Health Dis, 2014-03-27;13(0):57.
Species: Human
Sample Types: Serum
-
Regional adipose tissue hormone/cytokine production before and after weight loss in abdominally obese women.
Authors: You T, Wang X, Murphy K, Lyles M, Demons J, Yang R, Gong D, Nicklas B
Obesity (Silver Spring), 2014-03-25;22(7):1679-84.
Species: Human
Sample Types: Plasma
-
Serum levels of apoptosis inhibitor of macrophage are associated with hepatic fibrosis in patients with chronic hepatitis C.
Authors: Mera K, Uto H, Mawatari S, Ido A, Yoshimine Y, Nosaki T, Oda K, Tabu K, Kumagai K, Tamai T, Moriuchi A, Oketani M, Shimada Y, Hidaka M, Eguchi S, Tsubouchi H
BMC Gastroenterol, 2014-02-13;14(0):27.
Species: Human
Sample Types: Serum
-
Leptin is associated with vascular endothelial function in overweight patients with type 2 diabetes.
Authors: Morioka T, Emoto M, Yamazaki Y, Kawano N, Imamura S, Numaguchi R, Urata H, Motoyama K, Mori K, Fukumoto S, Koyama H, Shoji T, Inaba M
Cardiovasc Diabetol, 2014-01-10;13(0):10.
Species: Human
Sample Types: Plasma
-
Adiponectin is a candidate biomarker of lower extremity bone density in men with chronic spinal cord injury.
Authors: Doherty A, Battaglino R, Donovan J, Gagnon D, Lazzari A, Garshick E, Zafonte R, Morse L
J Bone Miner Res, 2014-01-01;29(1):251-9.
Species: Human
Sample Types: Plasma
-
Association between traffic-related air pollution, subclinical inflammation and impaired glucose metabolism: results from the SALIA study.
Authors: Teichert T, Vossoughi M, Vierkotter A, Sugiri D, Schikowski T, Schulte T, Roden M, Luckhaus C, Herder C, Kramer U
PLoS ONE, 2013-12-10;8(12):e83042.
Species: Human
Sample Types: Plasma
-
Brain-derived neurotrophic factor in human subjects with function-altering melanocortin-4 receptor variants.
Authors: Hohenadel M, Thearle M, Grice B, Huang H, Dai M, Tao Y, Hunter L, Palaguachi G, Mou Z, Kim R, Tsang M, Haack K, Voruganti V, Cole S, Butte N, Comuzzie A, Muller Y, Baier L, Krakoff J, Knowler W, Yanovski J, Han J
Int J Obes (Lond), 2013-11-26;38(8):1068-74.
Species: Human
Sample Types: Serum
-
A prospective study of circulating adipokine levels and risk of multiple myeloma.
Authors: Hofmann J, Liao L, Pollak M, Wang Y, Pfeiffer R, Baris D, Andreotti G, Lan Q, Landgren O, Rothman N, Purdue M
Blood, 2012-09-24;120(22):4418-20.
Species: Human
Sample Types: Plasma
-
Alterations of leptin in the course of inflammation and severe sepsis.
BMC Infect Dis, 2012-09-14;12(0):217.
Species: Human
Sample Types: Serum
-
The type and quantity of dietary fat and carbohydrate alter faecal microbiome and short-chain fatty acid excretion in a metabolic syndrome 'at-risk' population.
Authors: Fava, F, Gitau, R, Griffin, B A, Gibson, G R, Tuohy, K M, Lovegrove, J A
Int J Obes (Lond), 2012-03-13;37(2):216-23.
Species: Human
Sample Types: Plasma
-
Adipocytokines and CD34 progenitor cells in Alzheimer's disease.
Authors: Bigalke B, Schreitmuller B, Sopova K, Paul A, Stransky E, Gawaz M, Stellos K, Laske C
PLoS ONE, 2011-05-25;6(5):e20286.
Species: Human
Sample Types: Plasma
-
Effects of dietary fat modification on insulin sensitivity and on other risk factors of the metabolic syndrome-LIPGENE: a European randomized dietary intervention study.
Authors: Tierney AC, McMonagle J, Shaw DI, Gulseth HL, Helal O, Saris WH, Paniagua JA, Golabek-Leszczynska I, Defoort C, Williams CM, Karsltrom B, Vessby B, Dembinska-Kiec A, Lopez-Miranda J, Blaak EE, Drevon CA, Gibney MJ, Lovegrove JA, Roche HM
Int J Obes (Lond), 2010-10-12;35(6):800-9.
Species: Human
Sample Types: Serum
-
Differential adaptation of human gut microbiota to bariatric surgery-induced weight loss: links with metabolic and low-grade inflammation markers.
Authors: Furet JP, Kong LC, Tap J, Poitou C, Basdevant A, Bouillot JL, Mariat D, Corthier G, Dore J, Henegar C, Rizkalla S, Clement K
Diabetes, 2010-09-28;59(12):3049-57.
Species: Human
Sample Types: Plasma
-
Leptin exacerbates sepsis-mediated morbidity and mortality.
Authors: Shapiro NI, Khankin EV, van Meurs M
J. Immunol., 2010-06-02;185(1):517-24.
Species: Human
Sample Types: Plasma
-
Exenatide affects circulating cardiovascular risk biomarkers independently of changes in body composition.
Authors: Bunck MC, Diamant M, Eliasson B, Corner A, Shaginian RM, Heine RJ, Taskinen MR, Yki-Jarvinen H, Smith U
Diabetes Care, 2010-04-27;33(8):1734-7.
Species: Human
Sample Types: Serum
-
Improvements in coronary heart disease risk indicators by alternate-day fasting involve adipose tissue modulations.
Authors: Bhutani S, Klempel MC, Berger RA, Varady KA
Obesity (Silver Spring), 2010-03-18;18(11):2152-9.
Species: Human
Sample Types: Plasma
-
Environmental tobacco smoke and cardiometabolic risk in young children: results from a survey in south-west Germany.
Authors: Nagel G, Arnold FJ, Wilhelm M, Link B, Zoellner I, Koenig W
Eur. Heart J., 2009-05-24;30(15):1885-93.
Species: Human
Sample Types: Plasma
-
HIV increases markers of cardiovascular risk: results from a randomized, treatment interruption trial.
Authors: Calmy A, Gayet-Ageron A, Montecucco F, Nguyen A, Mach F, Burger F, Ubolyam S, Carr A, Ruxungtham K, Hirschel B, Ananworanich J
AIDS, 2009-05-15;23(8):929-39.
Species: Human
Sample Types: Plasma
-
Absence of leptin resistance in platelets from morbidly obese individuals may contribute to the increased thrombosis risk in obesity.
Authors: Dellas C, Schafer K, Rohm I, Lankeit M, Ellrott T, Faustin V, Riggert J, Hasenfuss G, Konstantinides S
Thromb. Haemost., 2008-12-01;100(6):1123-9.
Species: Human
Sample Types: Plasma
-
Positive energy balance is associated with accelerated muscle atrophy and increased erythrocyte glutathione turnover during 5 wk of bed rest.
Authors: Biolo G, Agostini F, Simunic B, Sturma M, Torelli L, Preiser JC, Deby-Dupont G, Magni P, Strollo F, di Prampero P, Guarnieri G, Mekjavic IB, Pisot R, Narici MV
Am. J. Clin. Nutr., 2008-10-01;88(4):950-8.
Species: Human
Sample Types: Plasma
-
Diurnal variation of human sweet taste recognition thresholds is correlated with plasma leptin levels.
Authors: Nakamura Y, Sanematsu K, Ohta R, Shirosaki S, Koyano K, Nonaka K, Shigemura N, Ninomiya Y
Diabetes, 2008-07-15;57(10):2661-5.
Species: Human
Sample Types: Plasma
-
Gene expression profiling of human skeletal muscle in response to stabilized weight loss.
Authors: Larrouy D, Barbe P, Valle C, Dejean S, Pelloux V, Thalamas C, Bastard JP, Le Bouil A, Diquet B, Clement K, Langin D, Viguerie N
Am. J. Clin. Nutr., 2008-07-01;88(1):125-32.
Species: Human
Sample Types: Plasma
-
Retinol-binding protein 4 and lipocalin-2 in childhood and adolescent obesity: when children are not just "small adults".
Authors: Kanaka-Gantenbein C, Margeli A, Pervanidou P, Sakka S, Mastorakos G, Chrousos GP, Papassotiriou I
Clin. Chem., 2008-05-16;54(7):1176-82.
Species: Human
Sample Types: Serum
-
The levels of steroid hormones and cytokines in individual follicles are not associated with the fertilization outcome after intracytoplasmic sperm injection.
Authors: Asimakopoulos B, Abu-Hassan D, Metzen E, Al-Hasani S, Diedrich K, Nikolettos N
Fertil. Steril., 2007-11-05;90(1):60-4.
Species: Human
Sample Types: Follicular Fluid
-
Obesity, adipokines, and abdominal aortic aneurysm: Health in Men study.
Authors: Golledge J, Clancy P, Jamrozik K, Norman PE
Circulation, 2007-10-29;116(20):2275-9.
Species: Human
Sample Types: Serum
-
Nitrosative stress predicts the presence and severity of nonalcoholic fatty liver at different stages of the development of insulin resistance and metabolic syndrome: possible role of vitamin A intake.
Authors: Musso G, Gambino R, De Michieli F, Biroli G, Premoli A, Pagano G, Bo S, Durazzo M, Cassader M
Am. J. Clin. Nutr., 2007-09-01;86(3):661-71.
Species: Human
Sample Types: Serum
-
The association of gastric leptin with oesophageal inflammation and metaplasia.
Authors: Francois F, Roper J, Goodman AJ, Pei Z, Ghumman M, Mourad M, de Perez AZ, Perez-Perez GI, Tseng CH, Blaser MJ
Gut, 2007-08-30;57(1):16-24.
Species: Human
Sample Types: Serum
-
Panel of markers can accurately predict endometriosis in a subset of patients.
Authors: Seeber B, Sammel MD, Fan X, Gerton GL, Shaunik A, Chittams J, Barnhart KT
Fertil. Steril., 2007-08-13;89(5):1073-81.
Species: Human
Sample Types: Serum
-
Muscle-specific knockout of PKC-lambda impairs glucose transport and induces metabolic and diabetic syndromes.
Authors: Farese RV, Sajan MP, Yang H, Li P, Mastorides S, Gower WR, Nimal S, Choi CS, Kim S, Shulman GI, Kahn CR, Braun U, Leitges M
J. Clin. Invest., 2007-08-01;117(8):2289-301.
Species: Human
Sample Types: Serum
-
Adiponectin and leptin in maternal serum, cord blood, and breast milk.
Authors: Weyermann M, Beermann C, Brenner H, Rothenbacher D
Clin. Chem., 2006-09-21;52(11):2095-102.
Species: Human
Sample Types: Serum
-
Plasma agouti-related protein levels in women with anorexia nervosa.
Authors: Moriya J, Takimoto Y, Yoshiuchi K
Psychoneuroendocrinology, 2006-08-14;31(9):1057-61.
Species: Human
Sample Types: Plasma
-
Altered hepatic expression of SREBP-1 and PPARgamma is associated with liver injury in insulin-resistant lipodystrophic HIV-infected patients.
Authors: Lemoine M, Barbu V, Girard PM, Kim M, Bastard JP, Wendum D, Paye F, Housset C, Capeau J, Serfaty L
AIDS, 2006-02-14;20(3):387-95.
Species: Human
Sample Types: Serum
-
Genetic regulation of the variation of circulating insulin-like growth factors and leptin in human pedigrees.
Authors: Pantsulaia Ia, Pantsulaia I, Trofimov S, Kobyliansky E, Livshits G
Metab. Clin. Exp., 2005-07-01;54(7):975-81.
Species: Human
Sample Types: Plasma
-
Adiponectin and other adipocytokines as predictors of markers of triglyceride-rich lipoprotein metabolism.
Authors: Chan DC, Watts GF, Ng TW, Uchida Y, Sakai N, Yamashita S, Barrett PH
Clin. Chem., 2005-01-13;51(3):578-85.
Species: Human
Sample Types: Plasma
-
Enhanced monocyte chemoattractant protein-3/CC chemokine ligand-7 in usual interstitial pneumonia.
Authors: Choi ES, Jakubzick C, Carpenter KJ, Kunkel SL, Evanoff H, Martinez FJ, Flaherty KR, Toews GB, Colby TV, Kazerooni EA, Gross BH, Travis WD, Hogaboam CM
Am. J. Respir. Crit. Care Med., 2004-06-10;170(5):508-15.
Species: Human
Sample Types: Cell Culture Supernates
-
Determinants of plasma leptin concentration in postmenopausal women.
Authors: Brooks-Asplund EM, Tupper CE, Daun JM, Kenney WL, Cannon JG
Mech. Ageing Dev., 2004-02-01;125(2):117-9.
Species: Human
Sample Types:
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